This ppt describes the difference between thermodynamic and kinetic stability of metal complexes

1. Thermodynamic and kinetic stability
of metal complexes, Part 3,
Thermodynamic vs Kinetic stability

2. Kinetically labile
Thermodynamically stable
Kinetically labile

3. [Ni(CN)4]2-, [Mn(CN)6]3-, [Cr(CN)6]3- are
thermodynamically stable but their kinetic
stability is different.
[Ni(CN)4]2- + 4 14CN- → [Ni(14CN)4]2- + 4CN- (very
fast)
Labile
[Mn(CN)6]3- + 6 14CN- → [Mn(14CN)6]3- + 6CN-
(slow)
Less labile
[Cr(CN)6]3- + 6 14CN- → [Cr(14CN)6]3- + 6CN-
(slowest)
Inert

4. The complex is kinetically inert towards substitution
Thermodynamically unstable in acid solution.
[Co(NH3)6]3+ + 6H3O+ → [Co(H2O)6]3+ + 6NH4
+

6. The thermodynamic and kinetic
terms are not related to each other