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JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
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WELCOME LETTER FROM DR.MEDICINE TEAM
Dear Readers,
We take great pleasure in welcoming you to our Dr.Medicine's
July month medical newsletter. We have created this magazine
with the intention of providing wide knowledge on different
aspects of medical field. This month we have taken notable
steps to improve the content and to add articles from different
fields of medicine such as dental, Natural medicine and
veterinary sciences.
The immediacy of e-based publication makes it possible for us
all to be fully connected to each other and to be directly
involved in ongoing knowledge construction.
We are happy to present you our Monthly magazine. We the
Dr.Medicine team members are working hard to give you the
best medical related contents, articles and health tips. We have
taken all steps to make this newsletter interesting and
informative. If you have any suggestions you are free to contact
us via Email @ drmedicineofficial@gmail.com
We are delighted that you are joining us as readers and hope
this will be very much informative.
Regards,
DR.MEDICINE TEAM
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Dr.Medicine is a non-registered and non-profit
online learning platform. This magazine is only for
educational purpose. The contents explained in
this newsletter is only a reference note. No
readers are instructed to follow the procedures
given in this newsletter. The readers are not
allowed to self-diagnose or treat diseases on their
own. Readers are hereby advised not to take any
medication or drugs without consulting a medical
practitioner or a pharmacist since the drugs may
cause side effects and may contraindicate
according to your medical conditions. Dr.Medicine
team will not be responsible for any losses or
damages in connection with the use of the
magazine.
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CONTENTS
Dr.Medicine Specials……………………………………….……04
FDA Approvals……………………………………………………..06
Vet Medicine………………………………………………………..11
First Aid………………………………………………………………..16
Ayurvedic Remedy………………………………………………..20
Elaborated Article………………………………………………...26
Random Articles……………………………………………………37
Dental Care…………………………………………………………..42
Editorial Board………………………………………………………..45
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BIRTH DEFECTS IN TWINS
Edited by, SNEHA MAVIS
Twins are more likely than singletons to experience birth
problems. Pregnancy difficulties, as well as subsequent birth
abnormalities, can impact fraternal and identical twins.
Defect in birth weight:
Twins are more likely to be underweight than new-born’s from
singleton pregnancies. This is due to the fact that they are born
prematurely. Because a foetus gains weight mostly in the last
trimester of pregnancy, preterm twins do not have the
opportunity to gain weight before birth. Those born before 32
weeks and weighing less than 3.3 pounds are at a higher risk of
long-term difficulties such as blindness, hearing loss, mental
retardation, and cerebral palsy.
Genital and urinary defects:
A study discovered that in pairs of opposite sex twins, boys had
a 29 percent higher risk of experiencing birth abnormalities.
Boys were twice as likely as girls to be born with abnormalities
affecting their genital and urinary organs. Researchers believe
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this is due to the fact that boys develop at a slower rate in the
womb than girls.
Congenital hip dislocation:
Congenital hip dislocation is a frequent birth condition in twins.
Researchers estimated that girls were ten times more likely
than boys to get congenital hip dislocation. A study also
discovered that boys were five times more likely than girls to be
born with a stomach-to-small-intestine blockage.
Twin to twin transfusion syndrome:
Monochorionic twins share a single placenta but have two
distinct amniotic sacs. The twins' blood supply is connected by
the same placenta, allowing blood to circulate between them. If
the blood flow is uneven, the twins will grow at different rates.
This leads to a condition in which the smaller twin pumps blood
to the larger twin. The condition is known as twin to twin
transfusion syndrome. The donor twin's blood supply will
gradually deteriorate, resulting in anaemia and a reduction in
amniotic fluid. The receiver twin will have an excessive blood
supply, which will result in increased urine production, amniotic
sac bloating.
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ZyCov-D, WORLDS FIRST PLASMA DNA VACCINE
Edited by, JOHN FELIX
ZyCov-D being developed by Cadila Healthcare with
support from the Biotechnology Industry Research
Assistance Council will be the world’s first DNA
vaccine against Infection with SARS-CoV-2 if approved
by the regulators.
The Zydus Cadila has applied to central Drugs Standard
Control Organisation (CDSCO), the national drugs
regulator seeking Emergency Use Authorisation for
ZyCov-D.
HOW DOES IT WORK?
This vaccine uses a genetically engineered, non-
replicative type of DNA molecule called PLASMID.
These plasmids are coded with instructions to develop
spike proteins like that of SARS-CoV-2. This vaccine
gives a code to cells in the recipient’s body.
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This results in making spiky layer of the Corona virus.
The Immune system develop antibodies against these
spike proteins in response. The ZyCov-D is
administered using a spring powered device where the
fluid penetrates the skin and avoids the use of Needles.
This vaccine will be administered in 3 doses, with
an interval of 28 days between each of the three doses.
EFFICACY:
ZyCov-D has undergone Phase 1, 2 and 3 clinical
trials involving over 28,000 Participants. Over a
thousand of these participants were of ages
between 12-18 years. According to the trial data, the
vaccine is being able to prevent Symptomatic COVID-
19 up to 67% in vaccinated individuals. The vaccine can
prevent from developing severe symptoms and can
prevent death.
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FDA APPROVES RYLAZE, IN THE CHEMOTHERAPEUTIC
REGIMEN OF LYMPHOBLASTIC CANCERS
Edited by, JASPER VICTORIA
Lymphoblastic leukaemia and lymphoblastic lymphoma
are the most common type of childhood cancer.
Asparaginase, an enzyme is a component in the
chemotherapeutic regimen for various cancers in which
they drive low the essential substances needed for the
survival of the tumour cells and hence kill them. It is
usually derived from Escherichia coli.
Since some patients are allergic to asparaginase, they
require an alternative to substitute and elicit their anti-
cancerous action.
The FDA hence approved Rylaze, a product of the Jazz
Pharmaceuticals, as an alternative to asparaginase in
the chemotherapeutic regimen of asparaginase allergic
patients having lymphoblastic leukaemia and
lymphoblastic lymphoma.
It may be used in children as well as in adults. The
safety and efficacy of Rylaze is based on a study in
which 102 asparaginase allergic cancer patients in
whom, Rylaze was administered and monitored for
activity similar to asparaginase.
94% of the enrolled patients showed similar effect with
Rylaze as in asparaginase at the therapeutic dose.
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Hypersensitivity, toxicity of the liver and pancreas,
haemorrhage and blood clots were the most common
side-effects observed during the study.
This new drug may therefore add on potential benefits
and aid in the treatment of cancers in children as well as
in adults with asparaginase allergies.
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"ARTIFICIAL PANCREAS" TREATMENT FOR TYPE 1
DIABETES
Edited by, SRIRAM
A new data suggests that Insulet's Omnipod artificial
Insulin delivery system makes better glucose control in
people with Type 1 Diabetes as young as 2 years of
age.
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The Omnipod 5 system comprises of a tubing free
Insulin filled delivery 'pod' with the Dexcom G6
continuous glucose monitor and an algorithm build into
the pod which connects the two devices through a
mobile application to semi-automatic insulin delivery.
This is currently under review by US food and Drug
Administration. The company expects to launch it in
limited release during the later end of 2021
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CANINE PARVOVIRUS INFECTION
R.A.VALARMATHI
VETERINARY COLLEGE AND RESEARCH
INSTITUTE, TIRUNELVLI
ABSTRACT:
Canine parvovirus is highly contagious disease affecting dogs.
Parvovirus is relatively a new disease appeared in the late
1970s. Two virologists Dr. Leland Carmichael and Dr. Max
Appel first isolated the parvovirus in 1978 at The Baker
institute for animal health. They also developed the first
vaccine for parvo in 1979.
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KEYWORDS: Hemorrhagic enteritis, Bloody diarrhea, CPV-2,
Myocardial form, Enteric form, Vaccination
INTRODUCTION:
There are several parvovirus that infect different animal
species worldwide. Parvovirus is a single stranded
unenveloped DNA virus, that are comparatively hardy and
survives extreme PH, temperature and even some common
disinfectants like chloroform. Two types of CPV is identified
so far, CPV 1 and CPV 2 although CPV-2 is the one commonly
affecting only dogs. This is closely related to Feline pan
leukopenia virus, mink virus and raccoon parvovirus.
ETIOLOGY: Canine parvovirus type 2
TRANSMISSION:
Canine parvovirus is transmitted directly or indirectly among
dogs. The direct transmission is by close contact with the
affected animal, and the indirect transmission is through
faeces. The virus shed in the faeces of the affected dogs and
remain alive in the environment for years. The infection is
mainly due to the ingestion of the contaminated faeces.
PARVO VIRAL INFECTION:
The disease occurs in two forms, enteric form and myocardial
form. Of both myocardial form often affects the pup less
than two weeks of age. The virus multiplies and grows only in
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actively dividing cells. In first two weeks of age, there will be
a rapid cardiac myocyte replication so after entering into the
body the virus enters cardiac fibres and replicate quickly and
causes myofibre necrosis which leads to acute myocarditis.
After 2-3 weeks, the intestinal epithelium starts replicating
actively in the pup’s body so in enteric form after the
ingestion of contaminated faeces, the virus enters the
intestinal epithelium and replicates. The virus alters the
absorbtion and increase permeability. This causes vomiting in
pups and subsequently diarrhea in older pups. Then due to
endotoxins secondary bacterial complications will occur and
death will be the sequel if untreated.
CLINICAL SIGNS:
• ENTERIC FORM: Pyrexia (104-106F), Vomition- clear to
bile coloured or blood stained, Diarrhea-greyish to
yellow grey in colour and blood streaked, dehydration,
weight loss, Mucopurulent nasal discharge.
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• MYOCARDIAC FORM: Dyspnoea, Retching, Terminal
convulsion, Cyanosis of mucosa.
DIAGNOSIS:
Diagnosis is based on the history, from the clinical signs and
age of the dog, vaccination it would be easy to diagnose the
disease. Another method is electron microscopy of negatively
stained faecal sample reveal fragments or whole CPV.
Serological tests such as immunofluorescence test of the
tissues or myocytes could be done as confirmatory tests.
HOW TO TAKE CARE OF PUP INFECTED WITH CPV?
Isolate the infected dog away from other dogs because
faeces is the source of transmission. Due to diarrhea apart
from medications provide them with cold water. Feed them
vanilla flavour ice cream and make sure to avoid chocolate
flavoured ice cream as chocolate is toxic to dogs. Also feed
them with coconut water to provide nutrients. Post infection
isolation is also compulsory to avoid spread of disease to
other dogs.
TREATMENT: There is no specific antiviral therapy so the
cases are managed by symptomatic treatment only. The
myocardial form is often cannot be treated due to its
asymptomatic condition however enteric form can be
treated. The basic is fluid therapy. Ringers lactate solution is
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given in intravenously to encounter the metabolic acidosis
due to dehydration.
Antiemetic drugs like Ondansetron ( 0.1-1.0mg/kg) is given.
Antibiotic therapy with broad spectrum antibiotics such as
Ceftriaxone (1.5-5ml/10 kg B.wt)
A proton pump inhibitor drug such as pantoprazole (1mg/kg)
is used to reduce the acid in the stomach and to reduce ulcer.
PREVENTION AND CONTROL:
Parvo viral infection is highly contagious yet preventable.
Colostrum feeding is the foremost prevention for any other
disease for neonates.
CPV infection is one hundred percent preventable with
vaccination. The commonly called puppy vaccination DHPPI is
combined vaccine for Distemper, Hepatitis, Leptospira,
Parvovirus and Parainfluenza. Annual revaccination is
recommended for dogs to lead a healthy life. The virus is
inactivated by 0.5% formalin, Hydroxylamine, Other oxidizing
agents and ultraviolet radiation.
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SNAKE BITE
Edited by, SHEDINO
A snakebite is an injury caused by the bite of a snake,
especially a venomous snake. A common sign of a bite
from a venomous snake is the presence of two puncture
wounds from the animal's fangs. Sometimes venom
injection from the bite may occur. This may result in
redness, swelling, and severe pain at the area, which
may take up to an hour to appear.
COMMON POISONOUS SNAKES:
• Cobra
• Krait
• Russell’s viper
• Saw scaled viper
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TYPES OF SNAKE BITE:
Neurotoxic Bite Vasculotoxic Bite
Neurotoxic Bite:
The venom acts on the nervous system
• Can’t feel much pain
• Causes diplopia (double vision)
• Weakness in leg, hand etc.
Vasculotoxic Bite:
The venom acts on blood vessels and vascular system
• Damages blood
• Causes more pain
• Colour changes in the bitten area
Dry
Bite
Venoumus
Bite
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What should you do now?
• If a snake bite you, don’t be nervous or scared.
• Don’t cut out or suck out the bitten part. If you do so
the risk of infection increases.
• Do not move the bitten part. The poison may spread
faster.
• Do not tie the bitten part tightly because the
chances of blood clotting is higher.
• Closely monitor airway and breathing and be ready
to resuscitate if necessary.
• Cover the wound with loose and sterile bandages.
• Do not apply ice or water.
• Take the individual to the hospital immediately.
TREATMENT:
• Antivenoms remain the only specific treatment that
can potentially prevent or reverse most of the
effects of snakebite envenoming when administered
early in an adequate therapeutic dose.
• Early access to safe, affordable and effective
antivenoms is critical for minimizing morbidity and
mortality, and improving this access is a major
component of an emerging WHO strategy to control
snakebite envenoming.
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FACTS:
• If a king cobra bites, the person can survive only
for 20-30 minutes. Death rates are higher.
• There are no widely available medications to treat
king cobra bites. They are only available in
countries like Thailand.
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AYURVEDIC REMEDIES FOR REVERSAL OF
PREMATURED GRAY HAIR
Edited by, BALA KRISHNAN
Ayurveda is one of the ancient system of medicine,
practiced mostly in India and Nepal. According to
Ayurveda, wellness of an individual is connected to
balance between body, mind and spirit. If the mind, body
& spirit are in harmony with universe, the person have
good health.
This balance can be disrupted due to birth or genetic
defects, injuries, climate change, heart breaks, emotions
and age. According to Ayurveda every person is made
of 5 basic elements of universe (pancha bhoota).
Ayurvedic sages condense these five elements into 3
doshas-
• Vata (space, air),
• pitta (fire, water),
• kapha (water, earth)
Every person in the earth are made up of combination of
these 3 doshas.one person may be pitta dominant
another person may be vata dominant and so on. There
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should be a proper balance between these 3 doshas.
Health condition or illness may be result of imbalance of
these 3 doshas
Here pitta dominant individuals are prone to develop
premature grey hair in young age
Pitta:
This is very important dosha, it controls digestion and
metabolism. Pitta can be said as fire not in literal sense
but the person with pitta dominant when there is an
imbalance they will have the following symptoms:
• There will be excess heat generation
• They may get irritated easily
• Short temper.
• Sour, acidic state in mouth
• Excess hair fall
• Insomnia
• Premature grey hair etc.
Causes for premature grey hair:
• Nutritional :
Well balanced diet is important for healthy hair. All six
tastes should be in balanced form. For pitta dominants
salt and spice should be taken in limited amount.Lack of
vitamins, iron, and calcium on diet can result in grey
hair.
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• Life style:
Excessive physical activities and excess sun
exposure can aggravate pitta. Especially summer is
pitta season, so it can aggravate pitta. Smoking and
fasting will also result in pitta aggravation. Sleeping
late at night may cause grey hair (after 10 pm)
• Psychological:
Anger, stress, grief can aggravate pitta. Acute and
chronic stress will aggravate pitta.
• Genetics:
Pitta dominant person should maintain their diet and
modify life style to maintain good health
Reversing grey hair: As we know, when a person ages
(mid 30s), production of melanin in hair follicle
decreases it can't be reversed but premature grey hair
can be reversed by pacifying pitta.
Treating premature Grey Hair:
• HAIR OILS:
1)Coconut oil with curry leaves-Natural coolant
for scalp
2)Amla oil
3)Castor oil
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Regular application of hair oils in limited amount is
good for your hair. Take oil bath twice a week to pacify
excess heat in body.
• LIFESTYLE CHANGES:
1)Since summer is the season of pitta,
excessive heat weakens digestive system.
So the person who is pitta dominant in nature
should take food that reduce heat in body.
2)It is not encouraged to do strenuous activities
like workout, playing more in sunlight. So it is
recommended to participate in lighter
physical activity like yoga or little walk.
3)Take cool water showers. Eye region should
be given extra care. Wash off with cold water
in evening.
Any Heart break or emotional stress can result in
damage to skin and hair like fine line, breakouts and
premature grey hair. So it is important to recognize and
limit emotional stress.
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• DIET:
1)Chicken, shrimp, rabbit, venison, fish
(freshwater), egg (white) and buffalo meat.
Meats to avoid: Beef, egg yolk, duck, pork,
salmon, seafood, sardines, lamb, fish
(saltwater), tuna fish and turkey.
2)Spices such as Basil, black pepper,
coriander, ginger, fennel, mint, orange peel,
saffron, peppermint, cinnamon, dill,
cardamom, parsley and vanilla can be added
to diet.
Spices to avoid: Bay leaf, garlic, mace, hing,
nutmeg, mustard seeds, salt, sage, thyme,
cloves, fenugreek, rosemary and mace.
3)Sweet, juicy fruits, especially pears, can cool
a fiery Pitta quickly. Milk, sweet rice pudding,
coconut, and coconut juice, and milkshakes
made with ripe mangoes and almonds or
dates are examples of soothing Pitta-
pacifying foods.
4)Basmati rice is excellent for balancing Pitta.
Wheat is also good- fresh flatbreads made
with whole wheat flour (called atta or chapatti
flour and available at Indian grocery stores).
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5)Oats and amaranth are other Pitta-balancing
grains.
6)Carrots, asparagus, bitter leafy greens,
fennel, cruciferous vegetables such as
broccoli, cauliflower, and Brussels sprouts,
green beans and bitter gourd (in very small
quantities) are good vegetable choices.
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SUBSTANCE USE DISORDER RECOGNIZING
SYMPTOMS
Edited by, SOWNDHARYA
Drug addiction, also called substance use disorder, is a
disease that affects a person's brain and behaviour. This
leads to an inability to control the use of a legal or illegal
drug or medication. Substances such as alcohol,
marijuana and nicotine also are considered drugs. When
a person is addicted, they may continue using the drug
despite the harm it causes.
Drug addiction can start with experimental use of a
recreational drug in social situations. For some people,
the drug use becomes more frequent. For others,
particularly with opioids, drug addiction begins with
exposure to prescribed medications, or receiving
medications from a friend or relative who has been
prescribed the medication. The risk of addiction and how
fast you become addicted varies by drug. Some drugs,
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such as opioid painkillers, have a higher risk and cause
addiction more quickly than others.
As time passes, affected person may need larger doses
of the drug to get high. Soon they may need the drug
just to feel good. As their drug use increases, they may
find that it's increasingly difficult to go without the drug.
Attempts to stop drug use may cause intense cravings
and make them feel physically ill and symptoms
manifests as withdrawal symptoms.
SYMPTOMS
Drug addiction symptoms or behaviours include, among
others:
• Feeling that you have to use the drug regularly
• Having intense urges for the drug that block out any
other thoughts
• Over time, needing more of the drug to get the
same effect
• Taking larger amounts of the drug over a longer
period of time than intended
• Making certain that they maintain a supply of the
drug
• Spending money on the drug
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• Not meeting obligations and work responsibilities, or
cutting back on social or recreational activities because
of drug use
• Driving or doing other risky activities when they are
under the influence of the drug
• Failing in their attempts to stop using the drug
• Experiencing withdrawal symptoms when they
attempt to stop taking the drug
RECOGNIZING SIGNS OF DRUG USE OR
INTOXICATION
Signs and symptoms of drug use or intoxication may
vary, depending on the type of drug. Below you'll find
several examples.
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CANNABIS CONTAINING DRUGS (MARIJUANA AND
OTHERS)
People use cannabis by smoking, eating or inhaling a
vaporized form of the drug. Cannabis often precedes or
is used along with other substances, such as alcohol or
illegal drugs, and is often the first drug tried.
Signs and symptoms of recent use can include:
• A sense of euphoria or feeling "high"
• A heightened sense of visual, auditory and taste
perception
• Increased blood pressure and heart rate
• Red eyes
• Dry mouth
• Decreased coordination
• Difficulty concentrating or remembering
• Slowed reaction time
• Anxiety or paranoid thinking
• Cannabis odour on clothes or yellow fingertips
• Exaggerated cravings for certain foods at unusual
times
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K2, SPICE AND BATH SALTS
Two groups of synthetic drugs synthetic cannabinoids
and substituted or synthetic cathinones are illegal. The
effects of these drugs can be dangerous and
unpredictable, as there is no quality control and some
ingredients may not be known.
Signs and symptoms of recent use can include:
• A sense of euphoria or feeling "high"
• Elevated mood
• An altered sense of visual, auditory and taste
perception
• Extreme anxiety or agitation
• Paranoia
• Hallucinations
• Increased heart rate and blood pressure or heart
attack
• Vomiting
• Confusion
BARBITURATES, BENZODIAZEPINES AND
HYPNOTICS
Barbiturates, benzodiazepines and hypnotics are
prescription central nervous system depressants.
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They're often used and misused in search for a sense of
relaxation or a desire to "switch off" or forget stress-
related thoughts or feelings.
• Barbiturates. Examples include phenobarbital and
secobarbital (Seconal).
• Benzodiazepines. Examples include sedatives,
such as diazepam (Valium), alprazolam (Xanax),
lorazepam (Ativan), clonazepam (Klonopin) and
chlordiazepoxide (Librium).
• Hypnotics. Examples include prescription sleeping
medications such as zolpidem (Ambien, Intermezzo,
others) and zaleplon (Sonata).
Signs and symptoms of recent use can include:
• Drowsiness
• Slurred speech
• Lack of coordination
• Irritability or changes in mood
• Problems concentrating or thinking clearly
• Memory problems
• Involuntary eye movements
• Lack of inhibition
• Slowed breathing and reduced blood pressure
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• Falls or accidents
• Dizziness
METH (METHAMHETAMINE), COCAINE AND OTHER
STIMULANTS
Stimulants include amphetamines, meth
(methamphetamine), cocaine, methylphenidate and
amphetamine-dextroamphetamine. They are often used
and misused in search of a "high," or to boost energy, to
improve performance at work or school, or to lose
weight or control appetite.
Signs and symptoms of recent use can include:
• Feeling of exhilaration and excess confidence
• Increased alertness
• Increased energy and restlessness
• Behaviour changes or aggression
• Rapid or rambling speech
• Dilated pupils
• Confusion, delusions and hallucinations
• Irritability, anxiety or paranoia
• Changes in heart rate, blood pressure and body
temperature
• Nausea or vomiting with weight loss
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• Impaired judgment
• Nasal congestion and damage to the mucous
membrane of the nose (if snorting drugs)
• Mouth sores, gum disease and tooth decay from
smoking drugs ("meth mouth")
• Insomnia
• Depression as the drug wears off
CLUB DRUGS
Club drugs are commonly used at clubs, concerts and
parties. Examples include ecstasy or molly (MDMA),
gamma-hydroxybutyric acid (GHB), flunitrazepam
(Rohypnol) and ketamine. These drugs are not all in the
same category, but they share some similar effects and
dangers, including long-term harmful effects.
Because GHB and flunitrazepam can cause sedation,
muscle relaxation, confusion and memory loss, the
potential for sexual misconduct or sexual assault is
associated with the use of these drugs.
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
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34
Signs and symptoms of use of club drugs can include:
• Hallucinations
• Paranoia
• Dilated pupils
• Chills and sweating
• Involuntary shaking (tremors)
• Behaviour changes
• Muscle cramping and teeth clenching
• Muscle relaxation, poor coordination or problems
moving
• Reduced inhibitions
• Heightened or altered sense of sight, sound and
taste
• Poor judgment
• Memory problems or loss of memory
• Reduced consciousness
• Increased or decreased heart rate and blood
pressure
OPIOID PAINKILLERS
Opioids are narcotic, painkilling drugs produced from
opium or made synthetically. This class of drugs
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
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35
includes, among others, heroin, morphine, codeine,
methadone and oxycodone.
Sometimes called the "opioid epidemic," addiction to
opioid prescription pain medications has reached an
alarming rate across the United States. Some people
who've been using opioids over a long period of time
may need physician-prescribed temporary or long-term
drug substitution during treatment.
Signs and symptoms of narcotic use and dependence
can include:
• Reduced sense of pain
• Agitation, drowsiness or sedation
• Slurred speech
• Problems with attention and memory
• Constricted pupils
• Lack of awareness or inattention to surrounding
people and things
• Problems with coordination
• Depression
• Confusion
• Constipation
• Runny nose or nose sores (if snorting drugs)
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
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36
• Needle marks (if injecting drugs)
WHEN TO SEEK EMERGENCY HELP
Seek emergency help if the person
• May have overdosed
• Shows changes in consciousness
• Has trouble breathing
• Has seizures or convulsions
• Has signs of a possible heart attack, such as chest
pain or pressure
• Has any other troublesome physical or
psychological reaction to use of the drug
STAGING AN INTERVENTION
People struggling with addiction usually deny that their
drug use is problematic and are reluctant to seek
treatment. An intervention presents a loved one with a
structured opportunity to make changes before things
get even worse and can motivate someone to seek or
accept help.
SUBSTANCE ABUSE DISORDER – CAUSES,
COMPLICATIONS AND PREVENTION OF RELAPSE
(To be continued in the next month magazine)
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
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37
WHOLE GRAINS CAN SAVE LIVES?
Written by, SANTHOSH KUMAR
According to WHO, Cardiovascular Diseases (CVD) are
'the leading cause of death globally'. Most of the CVD
conditions causing death are the stroke and heart
attack. It seems that in US, a person dies every 32
seconds from CVD.
In order to provide awareness Doctors asked the people
to stop smoking, perform exercises, be physically active,
control obesity and overweight.
And later it was said that, eating healthier foods like
fruits, vegetables, grains, fishes, and poultry can reduce
a person's risk of CVD.
Now being still more specific, they say that whole grains
consumption prevents CVD at a greater proportion than
others.
Early signs for CVD include waist circumference of a
person, blood pressure, high density lipoprotein (HDL),
blood glucose, triglycerides etc.
Researchers conducted a test within a group of people
by asking them to consume whole grains and they found
that people who consumed lesser amount of whole
grains showed 1 inch increase in their waist
circumference and an increase in systolic blood
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
38
pressure and blood sugar levels whereas those who
consumed more showed only 0.5 increase in their waist
circumference.
SIGNIFICANCE OF WHOLE GRAINS:
The presence of dietary fibres in whole grains can have
a satiating effect and magnesium, potassium and
antioxidants may contribute to lowering blood pressure.
Soluble fibre may have a beneficial effect on post meal
blood sugar spikes due to the increase in pipe colic acid
betaine.
Researchers say that this was the first time they had
observed these many betaine compounds in the human
body.
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
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39
The Greater task.
Now the much bigger task is to covert a person's diet
from refined grains to whole grains. It is much harder to
ask a person to eat whole grains besides pasta, breads
etc.
So researchers are working for a way to make people
understand in order to reduce the mortality rate due to
CVD. People understand about drinking water to
maintain hydration, avoiding junk foods and also
exercises but eating whole grains is always a question
mark in the minds of people. Let’s hope that this
situation changes too...
MONKEY POX
Edited by, VAISHNAVI
The centres for disease control and prevention (CDC)
and the Texas Department of State Health Services
confirmed and proposed on July 15, 2021 about a case
of human monkey pox in U.S. who recently travelled
from Nigeria to U.S.
The person is currently hospitalized in Dallas. CDC is
contacting airline passengers and others who may had
been in contact with the patient during the flight travel
and in airport.
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
40
Travellers on the flights were instructed to wear masks
mandatorily during their travel and also in the airports
due to risk of ongoing COVID-19 pandemic. Therefore, it
is believed that the spread of monkey pox via droplets to
others on the planes and in the airports will be reduced.
Monkey pox is a rare but potentially serious viral illness
which occurs mostly in the remote areas of Africa,
according to WHO.
The virus lives in animals, including primates and
rodents, but it can sometimes "jump" from animals to
people.
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
41
The virus spreads from person to person mainly via
respiratory droplets, which can enter the body through
mucous membranes in the eyes, mouth and nose.
Additionally, monkey pox can also be transmitted if a
person has contact with lesions or body fluids of infected
persons or indirectly from contact with contaminated
clothing.
Monkey pox typically begins with flu-like illness and
swelling of the lymph nodes and progresses to a
widespread rash on face and body. Most infections lasts
for 2-4 weeks.
Monkey pox is from the same family as small pox but it
causes a milder infection.
This infection is fatal in about 1 in 100 people. However,
rates may be higher in people with less or weakened
immunity.
SUBSCRIBE TO OUR YOUTUBE CHANNEL FOR
MORE INFORMATIVE VIDEOS. WE ARE UPLOADING
INFORMATIVE VIDEOS ABOUT DISEASES, DRUGS,
HEALTHTIPS, SOCIAL AWARENESS AND MUCH
MORE. A DEDICATED CHANNEL FOR MEDICOS.
STAY SUBSCRIBED @ DR.MEDICINE.
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
42
DENTAL CARIES
Written by, R. MOHAMED ARSHAD HUSSAIN
It is also known as cavity. It is the most important and
common disease in teeth. It is mainly caused by bacteria’s of
different species. It causes permanently damaged teeth.
Other causes are consumption of high sucrose content foods,
improper oral hygiene, and enamel loss. It may occur in any
gender at any age. It is of various types like
• Pit & fissure caries
• Occlusal caries
• Interproximal caries
• Deep caries
• Grossly decayed caries.
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
43
SYMPTOMS:
Patient’s complaints:
• Pain
• Sensitivity
Dentist’s findings:
• Inflammation of tissue
• Cavity
• Abscess (In X-ray)
• Swelling
It can be diagnosed by direct visual, physically using dental
instruments and X-rays.
Saliva act as a super barrier against caries. Fluoride content in
water also reduces caries.
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
44
TREATMENT OPTIONS & PREVENTION:
• Proper brushing & oral hygiene prevents the formation
of caries
• At initial stage without involving pulp of root caries can
be treated by removal of caries and filling the cavity
with cements like amalgam, composite, glass ionomer
cement (GIC) in pit & fissure caries, occlusal carries and
interproximal caries.
• If the caries has involved pulp then it is treated
differently in primary dentition and permanent
dentition.
• In primary dentition, if pulp is involved but the tooth is
vital, then direct pulp capping therapy, indirect pulp
capping therapy or apexogenesis can be done.
• In primary dentition, if pulp is involved but the tooth is
non-vital, then pulpectomy or apexification can be done.
• In permanent dentition, if pulp is involved and whether
the tooth is vital or non-vital, Root canal treatment
(RCT) is done.
• Deep caries is treated by removal of caries and
placement of Zinc oxide Eugenol (ZOE), Zinc phosphate
cement, Zinc polycarboxylate cement or Glass Ionomer
cement (GIC).
• If grossly decayed, then extraction of tooth is done.
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
45
EDITORIAL BOARD
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
46
Thanks to,
R.A Valarmathi, Veterinary Science
Shedino. R, MBBS student (RUSSIA)
Bala Krishnan, Doctor of Pharmacy
Mohamed Arshad Hussain, Dental intern
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
47
THANK YOU FOR READING!
Hey there! Hope Dr.Medicine’s monthly Magazine was
helpful to you. To read our daily articles, medical updates
and medical news, please do stay tuned in our website and
other social media platforms.
You may also write your articles for the Monthly Magazine.
Sent your articles to our E-Mail ID.
Read Daily articles at:
https://doctormedicinepost.blogspot.com/
YOUTUBE:
https://www.youtube.com/channel/UCEwvLaPYvU5FxpLa7bj
QWEw (SUBSCRIBE NOW)
DO FOLLOW US IN ALL OUR SOCIAL MEDIA PLATFORMS.
E-MAIL US: drmedicineofficial@gmail.com
Do sent your suggestions to our E-mail ID. We are pleased
to hear from you.
REGARDS,
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
48
CONTACT: @shadesofmedicine (Instagram)
JULY 2021 | 25-07-2021 | ISSUE NO: 02
DR.MEDICINE
Monthly medical Magazine
---------------------------------------------------------------------------------------------------------
49

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Dr.Medicine Medical Magazine. July month

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  • 2. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 1 WELCOME LETTER FROM DR.MEDICINE TEAM Dear Readers, We take great pleasure in welcoming you to our Dr.Medicine's July month medical newsletter. We have created this magazine with the intention of providing wide knowledge on different aspects of medical field. This month we have taken notable steps to improve the content and to add articles from different fields of medicine such as dental, Natural medicine and veterinary sciences. The immediacy of e-based publication makes it possible for us all to be fully connected to each other and to be directly involved in ongoing knowledge construction. We are happy to present you our Monthly magazine. We the Dr.Medicine team members are working hard to give you the best medical related contents, articles and health tips. We have taken all steps to make this newsletter interesting and informative. If you have any suggestions you are free to contact us via Email @ drmedicineofficial@gmail.com We are delighted that you are joining us as readers and hope this will be very much informative. Regards, DR.MEDICINE TEAM
  • 3. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 2 Dr.Medicine is a non-registered and non-profit online learning platform. This magazine is only for educational purpose. The contents explained in this newsletter is only a reference note. No readers are instructed to follow the procedures given in this newsletter. The readers are not allowed to self-diagnose or treat diseases on their own. Readers are hereby advised not to take any medication or drugs without consulting a medical practitioner or a pharmacist since the drugs may cause side effects and may contraindicate according to your medical conditions. Dr.Medicine team will not be responsible for any losses or damages in connection with the use of the magazine.
  • 4. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 3 CONTENTS Dr.Medicine Specials……………………………………….……04 FDA Approvals……………………………………………………..06 Vet Medicine………………………………………………………..11 First Aid………………………………………………………………..16 Ayurvedic Remedy………………………………………………..20 Elaborated Article………………………………………………...26 Random Articles……………………………………………………37 Dental Care…………………………………………………………..42 Editorial Board………………………………………………………..45
  • 5. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 4 BIRTH DEFECTS IN TWINS Edited by, SNEHA MAVIS Twins are more likely than singletons to experience birth problems. Pregnancy difficulties, as well as subsequent birth abnormalities, can impact fraternal and identical twins. Defect in birth weight: Twins are more likely to be underweight than new-born’s from singleton pregnancies. This is due to the fact that they are born prematurely. Because a foetus gains weight mostly in the last trimester of pregnancy, preterm twins do not have the opportunity to gain weight before birth. Those born before 32 weeks and weighing less than 3.3 pounds are at a higher risk of long-term difficulties such as blindness, hearing loss, mental retardation, and cerebral palsy. Genital and urinary defects: A study discovered that in pairs of opposite sex twins, boys had a 29 percent higher risk of experiencing birth abnormalities. Boys were twice as likely as girls to be born with abnormalities affecting their genital and urinary organs. Researchers believe
  • 6. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 5 this is due to the fact that boys develop at a slower rate in the womb than girls. Congenital hip dislocation: Congenital hip dislocation is a frequent birth condition in twins. Researchers estimated that girls were ten times more likely than boys to get congenital hip dislocation. A study also discovered that boys were five times more likely than girls to be born with a stomach-to-small-intestine blockage. Twin to twin transfusion syndrome: Monochorionic twins share a single placenta but have two distinct amniotic sacs. The twins' blood supply is connected by the same placenta, allowing blood to circulate between them. If the blood flow is uneven, the twins will grow at different rates. This leads to a condition in which the smaller twin pumps blood to the larger twin. The condition is known as twin to twin transfusion syndrome. The donor twin's blood supply will gradually deteriorate, resulting in anaemia and a reduction in amniotic fluid. The receiver twin will have an excessive blood supply, which will result in increased urine production, amniotic sac bloating.
  • 7. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 6 ZyCov-D, WORLDS FIRST PLASMA DNA VACCINE Edited by, JOHN FELIX ZyCov-D being developed by Cadila Healthcare with support from the Biotechnology Industry Research Assistance Council will be the world’s first DNA vaccine against Infection with SARS-CoV-2 if approved by the regulators. The Zydus Cadila has applied to central Drugs Standard Control Organisation (CDSCO), the national drugs regulator seeking Emergency Use Authorisation for ZyCov-D. HOW DOES IT WORK? This vaccine uses a genetically engineered, non- replicative type of DNA molecule called PLASMID. These plasmids are coded with instructions to develop spike proteins like that of SARS-CoV-2. This vaccine gives a code to cells in the recipient’s body.
  • 8. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 7 This results in making spiky layer of the Corona virus. The Immune system develop antibodies against these spike proteins in response. The ZyCov-D is administered using a spring powered device where the fluid penetrates the skin and avoids the use of Needles. This vaccine will be administered in 3 doses, with an interval of 28 days between each of the three doses. EFFICACY: ZyCov-D has undergone Phase 1, 2 and 3 clinical trials involving over 28,000 Participants. Over a thousand of these participants were of ages between 12-18 years. According to the trial data, the vaccine is being able to prevent Symptomatic COVID- 19 up to 67% in vaccinated individuals. The vaccine can prevent from developing severe symptoms and can prevent death.
  • 9. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 8 FDA APPROVES RYLAZE, IN THE CHEMOTHERAPEUTIC REGIMEN OF LYMPHOBLASTIC CANCERS Edited by, JASPER VICTORIA Lymphoblastic leukaemia and lymphoblastic lymphoma are the most common type of childhood cancer. Asparaginase, an enzyme is a component in the chemotherapeutic regimen for various cancers in which they drive low the essential substances needed for the survival of the tumour cells and hence kill them. It is usually derived from Escherichia coli. Since some patients are allergic to asparaginase, they require an alternative to substitute and elicit their anti- cancerous action. The FDA hence approved Rylaze, a product of the Jazz Pharmaceuticals, as an alternative to asparaginase in the chemotherapeutic regimen of asparaginase allergic patients having lymphoblastic leukaemia and lymphoblastic lymphoma. It may be used in children as well as in adults. The safety and efficacy of Rylaze is based on a study in which 102 asparaginase allergic cancer patients in whom, Rylaze was administered and monitored for activity similar to asparaginase. 94% of the enrolled patients showed similar effect with Rylaze as in asparaginase at the therapeutic dose.
  • 10. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 9 Hypersensitivity, toxicity of the liver and pancreas, haemorrhage and blood clots were the most common side-effects observed during the study. This new drug may therefore add on potential benefits and aid in the treatment of cancers in children as well as in adults with asparaginase allergies. --------------------------------------------------------------------------------------------------------------------------------- "ARTIFICIAL PANCREAS" TREATMENT FOR TYPE 1 DIABETES Edited by, SRIRAM A new data suggests that Insulet's Omnipod artificial Insulin delivery system makes better glucose control in people with Type 1 Diabetes as young as 2 years of age.
  • 11. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 10 The Omnipod 5 system comprises of a tubing free Insulin filled delivery 'pod' with the Dexcom G6 continuous glucose monitor and an algorithm build into the pod which connects the two devices through a mobile application to semi-automatic insulin delivery. This is currently under review by US food and Drug Administration. The company expects to launch it in limited release during the later end of 2021
  • 12. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 11 CANINE PARVOVIRUS INFECTION R.A.VALARMATHI VETERINARY COLLEGE AND RESEARCH INSTITUTE, TIRUNELVLI ABSTRACT: Canine parvovirus is highly contagious disease affecting dogs. Parvovirus is relatively a new disease appeared in the late 1970s. Two virologists Dr. Leland Carmichael and Dr. Max Appel first isolated the parvovirus in 1978 at The Baker institute for animal health. They also developed the first vaccine for parvo in 1979.
  • 13. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 12 KEYWORDS: Hemorrhagic enteritis, Bloody diarrhea, CPV-2, Myocardial form, Enteric form, Vaccination INTRODUCTION: There are several parvovirus that infect different animal species worldwide. Parvovirus is a single stranded unenveloped DNA virus, that are comparatively hardy and survives extreme PH, temperature and even some common disinfectants like chloroform. Two types of CPV is identified so far, CPV 1 and CPV 2 although CPV-2 is the one commonly affecting only dogs. This is closely related to Feline pan leukopenia virus, mink virus and raccoon parvovirus. ETIOLOGY: Canine parvovirus type 2 TRANSMISSION: Canine parvovirus is transmitted directly or indirectly among dogs. The direct transmission is by close contact with the affected animal, and the indirect transmission is through faeces. The virus shed in the faeces of the affected dogs and remain alive in the environment for years. The infection is mainly due to the ingestion of the contaminated faeces. PARVO VIRAL INFECTION: The disease occurs in two forms, enteric form and myocardial form. Of both myocardial form often affects the pup less than two weeks of age. The virus multiplies and grows only in
  • 14. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 13 actively dividing cells. In first two weeks of age, there will be a rapid cardiac myocyte replication so after entering into the body the virus enters cardiac fibres and replicate quickly and causes myofibre necrosis which leads to acute myocarditis. After 2-3 weeks, the intestinal epithelium starts replicating actively in the pup’s body so in enteric form after the ingestion of contaminated faeces, the virus enters the intestinal epithelium and replicates. The virus alters the absorbtion and increase permeability. This causes vomiting in pups and subsequently diarrhea in older pups. Then due to endotoxins secondary bacterial complications will occur and death will be the sequel if untreated. CLINICAL SIGNS: • ENTERIC FORM: Pyrexia (104-106F), Vomition- clear to bile coloured or blood stained, Diarrhea-greyish to yellow grey in colour and blood streaked, dehydration, weight loss, Mucopurulent nasal discharge.
  • 15. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 14 • MYOCARDIAC FORM: Dyspnoea, Retching, Terminal convulsion, Cyanosis of mucosa. DIAGNOSIS: Diagnosis is based on the history, from the clinical signs and age of the dog, vaccination it would be easy to diagnose the disease. Another method is electron microscopy of negatively stained faecal sample reveal fragments or whole CPV. Serological tests such as immunofluorescence test of the tissues or myocytes could be done as confirmatory tests. HOW TO TAKE CARE OF PUP INFECTED WITH CPV? Isolate the infected dog away from other dogs because faeces is the source of transmission. Due to diarrhea apart from medications provide them with cold water. Feed them vanilla flavour ice cream and make sure to avoid chocolate flavoured ice cream as chocolate is toxic to dogs. Also feed them with coconut water to provide nutrients. Post infection isolation is also compulsory to avoid spread of disease to other dogs. TREATMENT: There is no specific antiviral therapy so the cases are managed by symptomatic treatment only. The myocardial form is often cannot be treated due to its asymptomatic condition however enteric form can be treated. The basic is fluid therapy. Ringers lactate solution is
  • 16. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 15 given in intravenously to encounter the metabolic acidosis due to dehydration. Antiemetic drugs like Ondansetron ( 0.1-1.0mg/kg) is given. Antibiotic therapy with broad spectrum antibiotics such as Ceftriaxone (1.5-5ml/10 kg B.wt) A proton pump inhibitor drug such as pantoprazole (1mg/kg) is used to reduce the acid in the stomach and to reduce ulcer. PREVENTION AND CONTROL: Parvo viral infection is highly contagious yet preventable. Colostrum feeding is the foremost prevention for any other disease for neonates. CPV infection is one hundred percent preventable with vaccination. The commonly called puppy vaccination DHPPI is combined vaccine for Distemper, Hepatitis, Leptospira, Parvovirus and Parainfluenza. Annual revaccination is recommended for dogs to lead a healthy life. The virus is inactivated by 0.5% formalin, Hydroxylamine, Other oxidizing agents and ultraviolet radiation.
  • 17. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 16 SNAKE BITE Edited by, SHEDINO A snakebite is an injury caused by the bite of a snake, especially a venomous snake. A common sign of a bite from a venomous snake is the presence of two puncture wounds from the animal's fangs. Sometimes venom injection from the bite may occur. This may result in redness, swelling, and severe pain at the area, which may take up to an hour to appear. COMMON POISONOUS SNAKES: • Cobra • Krait • Russell’s viper • Saw scaled viper
  • 18. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 17 TYPES OF SNAKE BITE: Neurotoxic Bite Vasculotoxic Bite Neurotoxic Bite: The venom acts on the nervous system • Can’t feel much pain • Causes diplopia (double vision) • Weakness in leg, hand etc. Vasculotoxic Bite: The venom acts on blood vessels and vascular system • Damages blood • Causes more pain • Colour changes in the bitten area Dry Bite Venoumus Bite
  • 19. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 18 What should you do now? • If a snake bite you, don’t be nervous or scared. • Don’t cut out or suck out the bitten part. If you do so the risk of infection increases. • Do not move the bitten part. The poison may spread faster. • Do not tie the bitten part tightly because the chances of blood clotting is higher. • Closely monitor airway and breathing and be ready to resuscitate if necessary. • Cover the wound with loose and sterile bandages. • Do not apply ice or water. • Take the individual to the hospital immediately. TREATMENT: • Antivenoms remain the only specific treatment that can potentially prevent or reverse most of the effects of snakebite envenoming when administered early in an adequate therapeutic dose. • Early access to safe, affordable and effective antivenoms is critical for minimizing morbidity and mortality, and improving this access is a major component of an emerging WHO strategy to control snakebite envenoming.
  • 20. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 19 FACTS: • If a king cobra bites, the person can survive only for 20-30 minutes. Death rates are higher. • There are no widely available medications to treat king cobra bites. They are only available in countries like Thailand.
  • 21. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 20 AYURVEDIC REMEDIES FOR REVERSAL OF PREMATURED GRAY HAIR Edited by, BALA KRISHNAN Ayurveda is one of the ancient system of medicine, practiced mostly in India and Nepal. According to Ayurveda, wellness of an individual is connected to balance between body, mind and spirit. If the mind, body & spirit are in harmony with universe, the person have good health. This balance can be disrupted due to birth or genetic defects, injuries, climate change, heart breaks, emotions and age. According to Ayurveda every person is made of 5 basic elements of universe (pancha bhoota). Ayurvedic sages condense these five elements into 3 doshas- • Vata (space, air), • pitta (fire, water), • kapha (water, earth) Every person in the earth are made up of combination of these 3 doshas.one person may be pitta dominant another person may be vata dominant and so on. There
  • 22. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 21 should be a proper balance between these 3 doshas. Health condition or illness may be result of imbalance of these 3 doshas Here pitta dominant individuals are prone to develop premature grey hair in young age Pitta: This is very important dosha, it controls digestion and metabolism. Pitta can be said as fire not in literal sense but the person with pitta dominant when there is an imbalance they will have the following symptoms: • There will be excess heat generation • They may get irritated easily • Short temper. • Sour, acidic state in mouth • Excess hair fall • Insomnia • Premature grey hair etc. Causes for premature grey hair: • Nutritional : Well balanced diet is important for healthy hair. All six tastes should be in balanced form. For pitta dominants salt and spice should be taken in limited amount.Lack of vitamins, iron, and calcium on diet can result in grey hair.
  • 23. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 22 • Life style: Excessive physical activities and excess sun exposure can aggravate pitta. Especially summer is pitta season, so it can aggravate pitta. Smoking and fasting will also result in pitta aggravation. Sleeping late at night may cause grey hair (after 10 pm) • Psychological: Anger, stress, grief can aggravate pitta. Acute and chronic stress will aggravate pitta. • Genetics: Pitta dominant person should maintain their diet and modify life style to maintain good health Reversing grey hair: As we know, when a person ages (mid 30s), production of melanin in hair follicle decreases it can't be reversed but premature grey hair can be reversed by pacifying pitta. Treating premature Grey Hair: • HAIR OILS: 1)Coconut oil with curry leaves-Natural coolant for scalp 2)Amla oil 3)Castor oil
  • 24. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 23 Regular application of hair oils in limited amount is good for your hair. Take oil bath twice a week to pacify excess heat in body. • LIFESTYLE CHANGES: 1)Since summer is the season of pitta, excessive heat weakens digestive system. So the person who is pitta dominant in nature should take food that reduce heat in body. 2)It is not encouraged to do strenuous activities like workout, playing more in sunlight. So it is recommended to participate in lighter physical activity like yoga or little walk. 3)Take cool water showers. Eye region should be given extra care. Wash off with cold water in evening. Any Heart break or emotional stress can result in damage to skin and hair like fine line, breakouts and premature grey hair. So it is important to recognize and limit emotional stress.
  • 25. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 24 • DIET: 1)Chicken, shrimp, rabbit, venison, fish (freshwater), egg (white) and buffalo meat. Meats to avoid: Beef, egg yolk, duck, pork, salmon, seafood, sardines, lamb, fish (saltwater), tuna fish and turkey. 2)Spices such as Basil, black pepper, coriander, ginger, fennel, mint, orange peel, saffron, peppermint, cinnamon, dill, cardamom, parsley and vanilla can be added to diet. Spices to avoid: Bay leaf, garlic, mace, hing, nutmeg, mustard seeds, salt, sage, thyme, cloves, fenugreek, rosemary and mace. 3)Sweet, juicy fruits, especially pears, can cool a fiery Pitta quickly. Milk, sweet rice pudding, coconut, and coconut juice, and milkshakes made with ripe mangoes and almonds or dates are examples of soothing Pitta- pacifying foods. 4)Basmati rice is excellent for balancing Pitta. Wheat is also good- fresh flatbreads made with whole wheat flour (called atta or chapatti flour and available at Indian grocery stores).
  • 26. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 25 5)Oats and amaranth are other Pitta-balancing grains. 6)Carrots, asparagus, bitter leafy greens, fennel, cruciferous vegetables such as broccoli, cauliflower, and Brussels sprouts, green beans and bitter gourd (in very small quantities) are good vegetable choices.
  • 27. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 26 SUBSTANCE USE DISORDER RECOGNIZING SYMPTOMS Edited by, SOWNDHARYA Drug addiction, also called substance use disorder, is a disease that affects a person's brain and behaviour. This leads to an inability to control the use of a legal or illegal drug or medication. Substances such as alcohol, marijuana and nicotine also are considered drugs. When a person is addicted, they may continue using the drug despite the harm it causes. Drug addiction can start with experimental use of a recreational drug in social situations. For some people, the drug use becomes more frequent. For others, particularly with opioids, drug addiction begins with exposure to prescribed medications, or receiving medications from a friend or relative who has been prescribed the medication. The risk of addiction and how fast you become addicted varies by drug. Some drugs,
  • 28. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 27 such as opioid painkillers, have a higher risk and cause addiction more quickly than others. As time passes, affected person may need larger doses of the drug to get high. Soon they may need the drug just to feel good. As their drug use increases, they may find that it's increasingly difficult to go without the drug. Attempts to stop drug use may cause intense cravings and make them feel physically ill and symptoms manifests as withdrawal symptoms. SYMPTOMS Drug addiction symptoms or behaviours include, among others: • Feeling that you have to use the drug regularly • Having intense urges for the drug that block out any other thoughts • Over time, needing more of the drug to get the same effect • Taking larger amounts of the drug over a longer period of time than intended • Making certain that they maintain a supply of the drug • Spending money on the drug
  • 29. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 28 • Not meeting obligations and work responsibilities, or cutting back on social or recreational activities because of drug use • Driving or doing other risky activities when they are under the influence of the drug • Failing in their attempts to stop using the drug • Experiencing withdrawal symptoms when they attempt to stop taking the drug RECOGNIZING SIGNS OF DRUG USE OR INTOXICATION Signs and symptoms of drug use or intoxication may vary, depending on the type of drug. Below you'll find several examples.
  • 30. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 29 CANNABIS CONTAINING DRUGS (MARIJUANA AND OTHERS) People use cannabis by smoking, eating or inhaling a vaporized form of the drug. Cannabis often precedes or is used along with other substances, such as alcohol or illegal drugs, and is often the first drug tried. Signs and symptoms of recent use can include: • A sense of euphoria or feeling "high" • A heightened sense of visual, auditory and taste perception • Increased blood pressure and heart rate • Red eyes • Dry mouth • Decreased coordination • Difficulty concentrating or remembering • Slowed reaction time • Anxiety or paranoid thinking • Cannabis odour on clothes or yellow fingertips • Exaggerated cravings for certain foods at unusual times
  • 31. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 30 K2, SPICE AND BATH SALTS Two groups of synthetic drugs synthetic cannabinoids and substituted or synthetic cathinones are illegal. The effects of these drugs can be dangerous and unpredictable, as there is no quality control and some ingredients may not be known. Signs and symptoms of recent use can include: • A sense of euphoria or feeling "high" • Elevated mood • An altered sense of visual, auditory and taste perception • Extreme anxiety or agitation • Paranoia • Hallucinations • Increased heart rate and blood pressure or heart attack • Vomiting • Confusion BARBITURATES, BENZODIAZEPINES AND HYPNOTICS Barbiturates, benzodiazepines and hypnotics are prescription central nervous system depressants.
  • 32. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 31 They're often used and misused in search for a sense of relaxation or a desire to "switch off" or forget stress- related thoughts or feelings. • Barbiturates. Examples include phenobarbital and secobarbital (Seconal). • Benzodiazepines. Examples include sedatives, such as diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), clonazepam (Klonopin) and chlordiazepoxide (Librium). • Hypnotics. Examples include prescription sleeping medications such as zolpidem (Ambien, Intermezzo, others) and zaleplon (Sonata). Signs and symptoms of recent use can include: • Drowsiness • Slurred speech • Lack of coordination • Irritability or changes in mood • Problems concentrating or thinking clearly • Memory problems • Involuntary eye movements • Lack of inhibition • Slowed breathing and reduced blood pressure
  • 33. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 32 • Falls or accidents • Dizziness METH (METHAMHETAMINE), COCAINE AND OTHER STIMULANTS Stimulants include amphetamines, meth (methamphetamine), cocaine, methylphenidate and amphetamine-dextroamphetamine. They are often used and misused in search of a "high," or to boost energy, to improve performance at work or school, or to lose weight or control appetite. Signs and symptoms of recent use can include: • Feeling of exhilaration and excess confidence • Increased alertness • Increased energy and restlessness • Behaviour changes or aggression • Rapid or rambling speech • Dilated pupils • Confusion, delusions and hallucinations • Irritability, anxiety or paranoia • Changes in heart rate, blood pressure and body temperature • Nausea or vomiting with weight loss
  • 34. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 33 • Impaired judgment • Nasal congestion and damage to the mucous membrane of the nose (if snorting drugs) • Mouth sores, gum disease and tooth decay from smoking drugs ("meth mouth") • Insomnia • Depression as the drug wears off CLUB DRUGS Club drugs are commonly used at clubs, concerts and parties. Examples include ecstasy or molly (MDMA), gamma-hydroxybutyric acid (GHB), flunitrazepam (Rohypnol) and ketamine. These drugs are not all in the same category, but they share some similar effects and dangers, including long-term harmful effects. Because GHB and flunitrazepam can cause sedation, muscle relaxation, confusion and memory loss, the potential for sexual misconduct or sexual assault is associated with the use of these drugs.
  • 35. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 34 Signs and symptoms of use of club drugs can include: • Hallucinations • Paranoia • Dilated pupils • Chills and sweating • Involuntary shaking (tremors) • Behaviour changes • Muscle cramping and teeth clenching • Muscle relaxation, poor coordination or problems moving • Reduced inhibitions • Heightened or altered sense of sight, sound and taste • Poor judgment • Memory problems or loss of memory • Reduced consciousness • Increased or decreased heart rate and blood pressure OPIOID PAINKILLERS Opioids are narcotic, painkilling drugs produced from opium or made synthetically. This class of drugs
  • 36. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 35 includes, among others, heroin, morphine, codeine, methadone and oxycodone. Sometimes called the "opioid epidemic," addiction to opioid prescription pain medications has reached an alarming rate across the United States. Some people who've been using opioids over a long period of time may need physician-prescribed temporary or long-term drug substitution during treatment. Signs and symptoms of narcotic use and dependence can include: • Reduced sense of pain • Agitation, drowsiness or sedation • Slurred speech • Problems with attention and memory • Constricted pupils • Lack of awareness or inattention to surrounding people and things • Problems with coordination • Depression • Confusion • Constipation • Runny nose or nose sores (if snorting drugs)
  • 37. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 36 • Needle marks (if injecting drugs) WHEN TO SEEK EMERGENCY HELP Seek emergency help if the person • May have overdosed • Shows changes in consciousness • Has trouble breathing • Has seizures or convulsions • Has signs of a possible heart attack, such as chest pain or pressure • Has any other troublesome physical or psychological reaction to use of the drug STAGING AN INTERVENTION People struggling with addiction usually deny that their drug use is problematic and are reluctant to seek treatment. An intervention presents a loved one with a structured opportunity to make changes before things get even worse and can motivate someone to seek or accept help. SUBSTANCE ABUSE DISORDER – CAUSES, COMPLICATIONS AND PREVENTION OF RELAPSE (To be continued in the next month magazine)
  • 38. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 37 WHOLE GRAINS CAN SAVE LIVES? Written by, SANTHOSH KUMAR According to WHO, Cardiovascular Diseases (CVD) are 'the leading cause of death globally'. Most of the CVD conditions causing death are the stroke and heart attack. It seems that in US, a person dies every 32 seconds from CVD. In order to provide awareness Doctors asked the people to stop smoking, perform exercises, be physically active, control obesity and overweight. And later it was said that, eating healthier foods like fruits, vegetables, grains, fishes, and poultry can reduce a person's risk of CVD. Now being still more specific, they say that whole grains consumption prevents CVD at a greater proportion than others. Early signs for CVD include waist circumference of a person, blood pressure, high density lipoprotein (HDL), blood glucose, triglycerides etc. Researchers conducted a test within a group of people by asking them to consume whole grains and they found that people who consumed lesser amount of whole grains showed 1 inch increase in their waist circumference and an increase in systolic blood
  • 39. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 38 pressure and blood sugar levels whereas those who consumed more showed only 0.5 increase in their waist circumference. SIGNIFICANCE OF WHOLE GRAINS: The presence of dietary fibres in whole grains can have a satiating effect and magnesium, potassium and antioxidants may contribute to lowering blood pressure. Soluble fibre may have a beneficial effect on post meal blood sugar spikes due to the increase in pipe colic acid betaine. Researchers say that this was the first time they had observed these many betaine compounds in the human body.
  • 40. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 39 The Greater task. Now the much bigger task is to covert a person's diet from refined grains to whole grains. It is much harder to ask a person to eat whole grains besides pasta, breads etc. So researchers are working for a way to make people understand in order to reduce the mortality rate due to CVD. People understand about drinking water to maintain hydration, avoiding junk foods and also exercises but eating whole grains is always a question mark in the minds of people. Let’s hope that this situation changes too... MONKEY POX Edited by, VAISHNAVI The centres for disease control and prevention (CDC) and the Texas Department of State Health Services confirmed and proposed on July 15, 2021 about a case of human monkey pox in U.S. who recently travelled from Nigeria to U.S. The person is currently hospitalized in Dallas. CDC is contacting airline passengers and others who may had been in contact with the patient during the flight travel and in airport.
  • 41. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 40 Travellers on the flights were instructed to wear masks mandatorily during their travel and also in the airports due to risk of ongoing COVID-19 pandemic. Therefore, it is believed that the spread of monkey pox via droplets to others on the planes and in the airports will be reduced. Monkey pox is a rare but potentially serious viral illness which occurs mostly in the remote areas of Africa, according to WHO. The virus lives in animals, including primates and rodents, but it can sometimes "jump" from animals to people.
  • 42. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 41 The virus spreads from person to person mainly via respiratory droplets, which can enter the body through mucous membranes in the eyes, mouth and nose. Additionally, monkey pox can also be transmitted if a person has contact with lesions or body fluids of infected persons or indirectly from contact with contaminated clothing. Monkey pox typically begins with flu-like illness and swelling of the lymph nodes and progresses to a widespread rash on face and body. Most infections lasts for 2-4 weeks. Monkey pox is from the same family as small pox but it causes a milder infection. This infection is fatal in about 1 in 100 people. However, rates may be higher in people with less or weakened immunity. SUBSCRIBE TO OUR YOUTUBE CHANNEL FOR MORE INFORMATIVE VIDEOS. WE ARE UPLOADING INFORMATIVE VIDEOS ABOUT DISEASES, DRUGS, HEALTHTIPS, SOCIAL AWARENESS AND MUCH MORE. A DEDICATED CHANNEL FOR MEDICOS. STAY SUBSCRIBED @ DR.MEDICINE.
  • 43. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 42 DENTAL CARIES Written by, R. MOHAMED ARSHAD HUSSAIN It is also known as cavity. It is the most important and common disease in teeth. It is mainly caused by bacteria’s of different species. It causes permanently damaged teeth. Other causes are consumption of high sucrose content foods, improper oral hygiene, and enamel loss. It may occur in any gender at any age. It is of various types like • Pit & fissure caries • Occlusal caries • Interproximal caries • Deep caries • Grossly decayed caries.
  • 44. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 43 SYMPTOMS: Patient’s complaints: • Pain • Sensitivity Dentist’s findings: • Inflammation of tissue • Cavity • Abscess (In X-ray) • Swelling It can be diagnosed by direct visual, physically using dental instruments and X-rays. Saliva act as a super barrier against caries. Fluoride content in water also reduces caries.
  • 45. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 44 TREATMENT OPTIONS & PREVENTION: • Proper brushing & oral hygiene prevents the formation of caries • At initial stage without involving pulp of root caries can be treated by removal of caries and filling the cavity with cements like amalgam, composite, glass ionomer cement (GIC) in pit & fissure caries, occlusal carries and interproximal caries. • If the caries has involved pulp then it is treated differently in primary dentition and permanent dentition. • In primary dentition, if pulp is involved but the tooth is vital, then direct pulp capping therapy, indirect pulp capping therapy or apexogenesis can be done. • In primary dentition, if pulp is involved but the tooth is non-vital, then pulpectomy or apexification can be done. • In permanent dentition, if pulp is involved and whether the tooth is vital or non-vital, Root canal treatment (RCT) is done. • Deep caries is treated by removal of caries and placement of Zinc oxide Eugenol (ZOE), Zinc phosphate cement, Zinc polycarboxylate cement or Glass Ionomer cement (GIC). • If grossly decayed, then extraction of tooth is done.
  • 46. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 45 EDITORIAL BOARD
  • 47. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 46 Thanks to, R.A Valarmathi, Veterinary Science Shedino. R, MBBS student (RUSSIA) Bala Krishnan, Doctor of Pharmacy Mohamed Arshad Hussain, Dental intern
  • 48. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 47 THANK YOU FOR READING! Hey there! Hope Dr.Medicine’s monthly Magazine was helpful to you. To read our daily articles, medical updates and medical news, please do stay tuned in our website and other social media platforms. You may also write your articles for the Monthly Magazine. Sent your articles to our E-Mail ID. Read Daily articles at: https://doctormedicinepost.blogspot.com/ YOUTUBE: https://www.youtube.com/channel/UCEwvLaPYvU5FxpLa7bj QWEw (SUBSCRIBE NOW) DO FOLLOW US IN ALL OUR SOCIAL MEDIA PLATFORMS. E-MAIL US: drmedicineofficial@gmail.com Do sent your suggestions to our E-mail ID. We are pleased to hear from you. REGARDS,
  • 49. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 48 CONTACT: @shadesofmedicine (Instagram)
  • 50. JULY 2021 | 25-07-2021 | ISSUE NO: 02 DR.MEDICINE Monthly medical Magazine --------------------------------------------------------------------------------------------------------- 49