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MID BRAIN :PART 2
( Anatomy of internal features of Midbrain at
the level of superior colliculi)
Dr Pooja Dhabhai
(Assistant Professor Anatomy
R.N.T. Medical College, Udaipur)
• Cut section of midbrain
,central grey matter
along with cerebral
aqueduct
• Substantia nigra, this
feature remain
common at both the
levels
• Crus cerebri remain
same at both the levels
TRANSVERSE SECTION OF MIDBRAIN AT
LEVEL OF SUPERIOR COLLICULI
Oculomotor nerve nuclear complex
• This section is at the level of superior colliculus
• Nuclei closely related with central grey matter
• There will be presence of Oculomotor nerve
nuclear complex , there are verious subdivisions,
each individual right and left side divided into
subdivisions .
• subdivision of oculomotor nerve complex are
1. Inferolateral nuclei: will supply fibers to inferior
rectus muscle
2. Ventromedial nucleus: it will supply fibres to
medial rectus muscle
3. Intermediate nucleus: it will supply fibres to
inferior oblique muscle
4. Caudal central nucleus: it will supply fibres to
levator palpebri superioris muscle
5. Median raphe nucleus: will supply the fibers to
superior rectus muscle
So here only two extraocular muscles are left
beyond oculomotor nucleus those are
Lateral rectus muscle supplied by abducent
nerve, superior oblique muscle supplied by
trochlear nerve
Oculomotor nerve complex will supply the
somatic efferent functional componant
(therefore they will supply these extraocular
muscles which are derived from somite)
Edinger westphal nucleus
Exactly cranial to oculomotor
nerve nucleus complex is
presence of
 Edinger westphal nucleus:
• it is a parasympathetic
component of oculomotor
nerve nuclear complex only
• but it will carry general visceral
efferent functional component
• it will supply parasympathetic
secretomotor fibers through
ciliary ganglion which will help
in constriction of pupil (it will
supply sphinctor pupile muscle),
it will supply one more muscle
called ciliaris muscle( it will do
accomodation for the near
vision)
 Mesencephalic nucleus
Red nucleus( main component of this
section)
 Red nucleus : present dorsal
to medial part of substantia
nigra
• In freshly cut sections it will
appear pink in colour because
of abundance of iron pigment
• It will be extending from the
level of superior colliculi till
almost the subthalamic nucleus
• This is a main component of
identification of midbrain at the
level of superior colliculus
• This Red nucleus will have
Ventral tegmental decussation
of forel: rubro spinal tract
Connections of Red Nucleus
Afferent:
1. cerebelorubral fibres( contralateral
half of cerebellum)(dentate
,emboliform ,globose)
A. emboliform ,globose connected to
Magnocelular portion of red
nucleus(older portion)
B. Dentate fibers connected to
parvocelular portion of red
nucleus(newer portion)
2. Cerebral hemisphere (ipsilateral)
Efferent: ( outgoing channel)
1. Rubrospinal tract
2. Rubrobulbar tract will supply efferent
fibers from red nucleus to motor nu
of trigeminal nerve and facial nerve
3. Rubroreticular tract
4. Rubrolivary tract
Dorsal tegmental decussation of meynert
Dorsal tegmental
decussation of meynert
(tectospinal
tract):efferent fibres
coming from superior
colliculi give crossing
and form this
decussation
Lamniscus (only three)
• Medial lamniscus
• Trigeminal lamniscus
• Spinal lamniscus
• These lamnisci are commen
with that of cross section at
the level of inferior colliculus
Lateral lamniscus is auditory
pathway ,it will submerged
with inferior colliculus so there
is no lateral lamniscus at this
level
 pretectal nucleus: present
anterolateral to superior
colliculi ,will directly supply
fibers to edinger westphal
nucelus (concerned with
pupillary light reflex)
Superior colliculi: ovoid mass present at the tectum
connections
• Afferent: fibers coming from
• Retinotectal: from Retina
• Corticotectal fibres: visual area 17,18,19
• Spinotectal fibres : will carry sensations in form
of cutaneous receptors (cutaneous sensations
from spinal cord to superior colliculus)
• Ipsilateral inferior colliculi: auditory impulses
are coordinated with visual impulses
• Efferent
Tectospinal tract ,
Tectobulbar: superior colliculi will send the fibres to
cranial nerve nuclei 3,4,6 nerves which is
required for the movement of head and neck,
movement of eye towards the source of sound
These two tracts are involved in
1. movement of eyes and h& n towards auditory
stimuli
2. movement of eyes and h& n towards cutaneous
stimulation
3. tight closure of eyelids when exposed to bright
light
4. scanning movements of the
objects(whenever your eyes are scanning the
objects which are moving to and frow) this
movement controlled by tectospinal as well
as tectobulbar tract
5. Moving the head and neck towards the
TRANSVERSE SECTION OF MIDBRAIN
AT LEVEL OF SUPERIOR COLLICULI
Clinical Anatomy at the level of
midbrain
WEBER’S SYNDROME
1. There may be Occlution of
oculomotor nerve
because of this there will
be Unilateral paralysis of
a)levator palpabre
superioris: therewill be
unilateral ptosis( drooping)
of eye lid
b)loss of sphinctor pupillae
and ciliaris muscle: pupil
will remain dilated and fix
c)Lateral sqint/lateral
statismus (lateral rectus is
normal)
2. Involvement of Pyramidal
tract: upper motor neuron
type of paralysis in opposite
side of body
BENEDIKT’S SYNDROME
• Lesion of red
nucleus:functions of red
nucleus also will lost
• Medial lamniscus is
involved : consious
muscle joint sensation
along with
touch,pressure,lost(contr
alateral half)
• Oculomotor nerve lesion
:symptoms of webers
syndrome
• Superior cerebellar
peduncle
PARINAUD’S SYNDROME
• Compression of
the tectum
region(by penial
gland)in the
area of superior
colliculi: it will
produce
upward gaze
syndrome
PARINAUD’S SYNDROME
A QUICK REVISION
TRANSVERSE SECTION OF MIDBRAIN
AT LEVEL OF SUPERIOR COLLICULI
THANK YOU

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Mid brain part 2

  • 1. MID BRAIN :PART 2 ( Anatomy of internal features of Midbrain at the level of superior colliculi) Dr Pooja Dhabhai (Assistant Professor Anatomy R.N.T. Medical College, Udaipur)
  • 2. • Cut section of midbrain ,central grey matter along with cerebral aqueduct • Substantia nigra, this feature remain common at both the levels • Crus cerebri remain same at both the levels
  • 3. TRANSVERSE SECTION OF MIDBRAIN AT LEVEL OF SUPERIOR COLLICULI
  • 4. Oculomotor nerve nuclear complex • This section is at the level of superior colliculus • Nuclei closely related with central grey matter • There will be presence of Oculomotor nerve nuclear complex , there are verious subdivisions, each individual right and left side divided into subdivisions . • subdivision of oculomotor nerve complex are 1. Inferolateral nuclei: will supply fibers to inferior rectus muscle 2. Ventromedial nucleus: it will supply fibres to medial rectus muscle 3. Intermediate nucleus: it will supply fibres to inferior oblique muscle 4. Caudal central nucleus: it will supply fibres to levator palpebri superioris muscle 5. Median raphe nucleus: will supply the fibers to superior rectus muscle So here only two extraocular muscles are left beyond oculomotor nucleus those are Lateral rectus muscle supplied by abducent nerve, superior oblique muscle supplied by trochlear nerve Oculomotor nerve complex will supply the somatic efferent functional componant (therefore they will supply these extraocular muscles which are derived from somite)
  • 5. Edinger westphal nucleus Exactly cranial to oculomotor nerve nucleus complex is presence of  Edinger westphal nucleus: • it is a parasympathetic component of oculomotor nerve nuclear complex only • but it will carry general visceral efferent functional component • it will supply parasympathetic secretomotor fibers through ciliary ganglion which will help in constriction of pupil (it will supply sphinctor pupile muscle), it will supply one more muscle called ciliaris muscle( it will do accomodation for the near vision)  Mesencephalic nucleus
  • 6. Red nucleus( main component of this section)  Red nucleus : present dorsal to medial part of substantia nigra • In freshly cut sections it will appear pink in colour because of abundance of iron pigment • It will be extending from the level of superior colliculi till almost the subthalamic nucleus • This is a main component of identification of midbrain at the level of superior colliculus • This Red nucleus will have Ventral tegmental decussation of forel: rubro spinal tract
  • 7. Connections of Red Nucleus Afferent: 1. cerebelorubral fibres( contralateral half of cerebellum)(dentate ,emboliform ,globose) A. emboliform ,globose connected to Magnocelular portion of red nucleus(older portion) B. Dentate fibers connected to parvocelular portion of red nucleus(newer portion) 2. Cerebral hemisphere (ipsilateral) Efferent: ( outgoing channel) 1. Rubrospinal tract 2. Rubrobulbar tract will supply efferent fibers from red nucleus to motor nu of trigeminal nerve and facial nerve 3. Rubroreticular tract 4. Rubrolivary tract
  • 8. Dorsal tegmental decussation of meynert Dorsal tegmental decussation of meynert (tectospinal tract):efferent fibres coming from superior colliculi give crossing and form this decussation
  • 9. Lamniscus (only three) • Medial lamniscus • Trigeminal lamniscus • Spinal lamniscus • These lamnisci are commen with that of cross section at the level of inferior colliculus Lateral lamniscus is auditory pathway ,it will submerged with inferior colliculus so there is no lateral lamniscus at this level  pretectal nucleus: present anterolateral to superior colliculi ,will directly supply fibers to edinger westphal nucelus (concerned with pupillary light reflex)
  • 10. Superior colliculi: ovoid mass present at the tectum connections • Afferent: fibers coming from • Retinotectal: from Retina • Corticotectal fibres: visual area 17,18,19 • Spinotectal fibres : will carry sensations in form of cutaneous receptors (cutaneous sensations from spinal cord to superior colliculus) • Ipsilateral inferior colliculi: auditory impulses are coordinated with visual impulses • Efferent Tectospinal tract , Tectobulbar: superior colliculi will send the fibres to cranial nerve nuclei 3,4,6 nerves which is required for the movement of head and neck, movement of eye towards the source of sound These two tracts are involved in 1. movement of eyes and h& n towards auditory stimuli 2. movement of eyes and h& n towards cutaneous stimulation 3. tight closure of eyelids when exposed to bright light 4. scanning movements of the objects(whenever your eyes are scanning the objects which are moving to and frow) this movement controlled by tectospinal as well as tectobulbar tract 5. Moving the head and neck towards the
  • 11. TRANSVERSE SECTION OF MIDBRAIN AT LEVEL OF SUPERIOR COLLICULI
  • 12. Clinical Anatomy at the level of midbrain
  • 13. WEBER’S SYNDROME 1. There may be Occlution of oculomotor nerve because of this there will be Unilateral paralysis of a)levator palpabre superioris: therewill be unilateral ptosis( drooping) of eye lid b)loss of sphinctor pupillae and ciliaris muscle: pupil will remain dilated and fix c)Lateral sqint/lateral statismus (lateral rectus is normal) 2. Involvement of Pyramidal tract: upper motor neuron type of paralysis in opposite side of body
  • 14. BENEDIKT’S SYNDROME • Lesion of red nucleus:functions of red nucleus also will lost • Medial lamniscus is involved : consious muscle joint sensation along with touch,pressure,lost(contr alateral half) • Oculomotor nerve lesion :symptoms of webers syndrome • Superior cerebellar peduncle
  • 15. PARINAUD’S SYNDROME • Compression of the tectum region(by penial gland)in the area of superior colliculi: it will produce upward gaze syndrome
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  • 22. TRANSVERSE SECTION OF MIDBRAIN AT LEVEL OF SUPERIOR COLLICULI
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