1. Engineering to sustain

2. Clostridia and n-butanol - Multi-market
platforms for profitable introduction of
commodity scale renewable chemicals

3. Mission and History
Elcriton is inventing and commercializing technologies to
supplant fossil fuel consumption, reduce green house gas
emissions, and accelerate the expansion of cleantech
industries.
History:
•Evolved out of the academic laboratory of Professor Terry
Papoutsakis University of Delaware in 2009 - Bryan Tracy named
CEO is PI on research grants that seeded company
•2011 – license technology to the world’s largest biobutanol
producer
•2012 – Will sign a strategic partnership for development and
integration of hydrolysis technology and potentially for novel
separation technology

4. Mission and History
All non-dilutive funding and profitable by
the end of 2011.
History:
•Evolved out of the academic laboratory of Professor Terry
Papoutsakis University of Delaware in 2009 - Bryan Tracy named
CEO is PI on research grants that seeded company
•2011 – license technology to the world’s largest biobutanol
producer
•2012 – Will sign a strategic partnership for development and
integration of hydrolysis technology and potentially for novel
separation technology

5. Two platforms, numerous
markets
HO • Specialty chemical
• Biofuel (i.e., gasoline
n-butanol alternative and Jet A or JP-8)
• Chemical production
• Waste stream remediation &
upgrading
• Exotic applications - CDEPT
Clostridia genetic
engineering & bioprocessing

6. Specialty chemical market
>$5 (USD) billion/year n-butanol market
Chemical feedstock
•Glycol ethers (17%)
•Butyl acetate (21%)
•Butyl acrylate (39%)
Uses
Product formulations
•Paints/Primers
•Cosmetics
•Lubricating oils
•Etc.

7. Market need for sustainable solutions
Need  Driver
• Cost  increased propylene costs*
• Secured supply chains  unstable propylene supply
• Increasing demand (11.9% CAGR)  emerging markets
• Green solutions  Preferred buyer opportunities
• New & MUCH BIGGER market opportunities  gasoline
alternatives & jet fuel

8. Case for a biofuel - >$100B market
Compared to ethanol:
2. High energy content Butanol
3. Higher air to fuel ratio
Better MPG
4. Lower heat of vaporization
5. Less hygroscopic
6. Less corrosive to gasoline FLEXFUEL
infrastructure
7. Blending synergies with
ethanol

9. Elcriton niche in the butanol value chain
Feedstock Manufacture Distribution
or
Off-take
Mechanical Hydrolysis Separation/
prep. Purification
Pretreat- Fermentation ethanol/
ment acetone
butanol
heat/
energy
HO
enzyme
clostridia gas
Pretreatment & Conversion the Separations
Hydrolysis Elcriton way

10. Sugar to n-butanol technology
5-carbons
(xylose)
6-carbons
(glucose)
+
starch
hemicellulose
Metabolic Engineering
Considerations: Molecular-scale solutions to
•What’s it eating? multi-million dollar
•How fast should they grow?
•Can I reduce byproduct production?
bioprocessing impediments
•Can I integrate with purification?
•Can they tolerate hydrolysis byproducts?
•Can I shift production to another feedstock?

11. Clostridia bioprocessing platform
Strain development in clostridia and related species
• Genetic engineering technologies
• Opportunities for related, desirable species
Synthetic biology
• Novel pathways for new chemicals
• Opportunities in chemolithotrophic clostridia
Bioprocess development & integration
• Concurrent strain and bioreactor development
• Bioreactor and purification integration

12. Advantages of the multi-market,
platform approach
• Flexibility in business model development
• Early revenue generation (e.g., licensing)
• Demonstration of commercial credibility = de-risking
larger market opportunities
• Opportunities for Non-recurring revenues (NRR)
• Bootstrapping opportunities
• Reduce dilution in early rounds of fund raising
• Increase value proposition
• Expand options of later stage financing (e.g., debt
financing)

13. Clostridia bioprocessing platform
Green – Black processing
• Remediation and upgrading of industrial waste
• Glycerol, flue gases, methane and ag wastes
Gaseous fermentations
• Chemolithotropic fermentations
• Ideally CO2 to specialty chemicals – H2?
Renewable H2 production
• Photosynthetic & CO2 sequestration
• Algal photobioreactor & dewatering systems – DOE and
ARPA-E

14. For questions please contact:
Bryan P. Tracy, PhD
15 Reads Way Suite 106
New Castle, DE 19720
BryanTracy@elcriton.com
302-220-4760
864-921-5146