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Mitosis & Meiosis
Made By
Name: Carolyn Joseph
Reg.No: 16BCB0098
Course title: cell Biology and Biochemistry
Cell makes a copy of itself
1) Copy its DNA (part of a chromosome).
2) Copies are separated & sorted into two sides of the cell.
3) The cell then splits in two.
4) Part of each parent is carried to the two new cells.
5) Two EXACT daughter cells (same number of chromosomes)
Examples: skin, bones, internal organs
Mitosis
3/11/2018Carolyn Joseph (16BCB0098) 2
∗ Cell division that forms gametes (egg and sperm cells)
∗ GametesGametes have halfhalf the number of chromosomeschromosomes.
∗ Two divisionsTwo divisions (meiosis Imeiosis I and meiosis IImeiosis II).
∗ Part of each parent is carried to the four new cells.
∗ MeiosisMeiosis is similar to mitosismitosis with some chromosomal
differences.
Meiosis
3/11/2018Carolyn Joseph (16BCB0098) 3
Mitosis: Meiosis:
Each resulting cell still has chromosomes from parent cellsEach resulting cell still has chromosomes from parent cells
3/11/2018Carolyn Joseph (16BCB0098) 4
∗ MITosis takes one cell and Makes It Two
∗ Meiosis has to do with sex
∗ From the cell’s point of view:
∗ mITosis results in Identical Twins CELLS
∗ mEioSis results in Egg and Sperm
Tips
3/11/2018Carolyn Joseph (16BCB0098) 5
∗ Interphase I
∗ Meiosis I and Meiosis 2
∗ Similar to Mitosis EXCEPT changes in chromosomes
Cell Division in Sex Cells
3/11/2018Carolyn Joseph (16BCB0098) 6
∗ Similar to mitosismitosis interphase.
∗ ChromosomesChromosomes replicate (S phase).(S phase).
∗ Each duplicated chromosomechromosome consist of two
identical sister chromatidschromatids attached at their
centromerescentromeres.
Interphase IInterphase I
3/11/2018Carolyn Joseph (16BCB0098) 7
∗ Cell divisionCell division that reduces the chromosomechromosome
number by one-half.one-half.
∗ Four phasesFour phases:
a.a. prophase Iprophase I
b.b. metaphase Imetaphase I
c.c. anaphase Ianaphase I
d.d. telophase Itelophase I
Meiosis I (four phases)Meiosis I (four phases)
3/11/2018Carolyn Joseph (16BCB0098) 8
Prophase IProphase I
centrioles
spindle fiber
TETRAD
3/11/2018Carolyn Joseph (16BCB0098) 9
∗HHomologous chromosomesomologous chromosomes come
together to form a tetradtetrad.
∗TetradTetrad is two chromosomeschromosomes or four
chromatidschromatids (sister and nonsister
chromatids).
Prophase IProphase I
3/11/2018Carolyn Joseph (16BCB0098) 10
Homologous chromosomes
sister chromatids
paternal
sister chromatids
maternal
Tetrad
3/11/2018Carolyn Joseph (16BCB0098) 11
∗ Crossing overCrossing over: segments of nonsister chromatidschromatids break and
reattach to the other chromatidchromatid.
∗ Crossing overCrossing over causescauses variationvariation
Prophase 1 – Crossing OverProphase 1 – Crossing Over
3/11/2018Carolyn Joseph (16BCB0098) 12
Crossing Over - variationCrossing Over - variation
nonsister chromatids
chiasmata: site
of crossing over variation
Tetrad
3/11/2018Carolyn Joseph (16BCB0098) 13
∗ TetradsTetrads align on the in center of cell on spindle
∗ INDEPENDENT ASSORTMENT OCCURS:INDEPENDENT ASSORTMENT OCCURS:
1. Orientation of homologous pair to poles is random.
2. Variation
Metaphase IMetaphase I
OR
3/11/2018Carolyn Joseph (16BCB0098) 14
∗ Homologous chromosomesHomologous chromosomes separate and
move towards the poles.
∗ Sister chromatidsSister chromatids remain attached at their
centromerescentromeres.
Anaphase IAnaphase I
3/11/2018Carolyn Joseph (16BCB0098) 15
∗ Each pole now has haploidhaploid set of chromosomeschromosomes.
∗ CytokinesisCytokinesis occurs and two haploid daughter
cells are formed.
Telophase ITelophase I
3/11/2018Carolyn Joseph (16BCB0098) 16
∗ No interphase IINo interphase II
∗ Remember:Remember: Meiosis IIMeiosis II is similar to mitosismitosis
Meiosis IIMeiosis II
3/11/2018Carolyn Joseph (16BCB0098) 17
∗ same as prophaseprophase in mitosismitosis
Prophase IIProphase II
3/11/2018Carolyn Joseph (16BCB0098) 18
∗ same as metaphasemetaphase in mitosismitosis
Metaphase IIMetaphase II
3/11/2018Carolyn Joseph (16BCB0098) 19
∗ same as anaphaseanaphase in mitosismitosis
∗ sister chromatids separatesister chromatids separate
Anaphase IIAnaphase II
3/11/2018Carolyn Joseph (16BCB0098) 20
∗ Four haploid daughter cells producedFour haploid daughter cells produced
gametes = sperm or egggametes = sperm or egg
Telophase IITelophase II
3/11/2018Carolyn Joseph (16BCB0098) 21
2n
diploid
n haploid
n haploid
3/11/2018Carolyn Joseph (16BCB0098) 22

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Mitosis& meiosis

  • 1. Mitosis & Meiosis Made By Name: Carolyn Joseph Reg.No: 16BCB0098 Course title: cell Biology and Biochemistry
  • 2. Cell makes a copy of itself 1) Copy its DNA (part of a chromosome). 2) Copies are separated & sorted into two sides of the cell. 3) The cell then splits in two. 4) Part of each parent is carried to the two new cells. 5) Two EXACT daughter cells (same number of chromosomes) Examples: skin, bones, internal organs Mitosis 3/11/2018Carolyn Joseph (16BCB0098) 2
  • 3. ∗ Cell division that forms gametes (egg and sperm cells) ∗ GametesGametes have halfhalf the number of chromosomeschromosomes. ∗ Two divisionsTwo divisions (meiosis Imeiosis I and meiosis IImeiosis II). ∗ Part of each parent is carried to the four new cells. ∗ MeiosisMeiosis is similar to mitosismitosis with some chromosomal differences. Meiosis 3/11/2018Carolyn Joseph (16BCB0098) 3
  • 4. Mitosis: Meiosis: Each resulting cell still has chromosomes from parent cellsEach resulting cell still has chromosomes from parent cells 3/11/2018Carolyn Joseph (16BCB0098) 4
  • 5. ∗ MITosis takes one cell and Makes It Two ∗ Meiosis has to do with sex ∗ From the cell’s point of view: ∗ mITosis results in Identical Twins CELLS ∗ mEioSis results in Egg and Sperm Tips 3/11/2018Carolyn Joseph (16BCB0098) 5
  • 6. ∗ Interphase I ∗ Meiosis I and Meiosis 2 ∗ Similar to Mitosis EXCEPT changes in chromosomes Cell Division in Sex Cells 3/11/2018Carolyn Joseph (16BCB0098) 6
  • 7. ∗ Similar to mitosismitosis interphase. ∗ ChromosomesChromosomes replicate (S phase).(S phase). ∗ Each duplicated chromosomechromosome consist of two identical sister chromatidschromatids attached at their centromerescentromeres. Interphase IInterphase I 3/11/2018Carolyn Joseph (16BCB0098) 7
  • 8. ∗ Cell divisionCell division that reduces the chromosomechromosome number by one-half.one-half. ∗ Four phasesFour phases: a.a. prophase Iprophase I b.b. metaphase Imetaphase I c.c. anaphase Ianaphase I d.d. telophase Itelophase I Meiosis I (four phases)Meiosis I (four phases) 3/11/2018Carolyn Joseph (16BCB0098) 8
  • 9. Prophase IProphase I centrioles spindle fiber TETRAD 3/11/2018Carolyn Joseph (16BCB0098) 9
  • 10. ∗HHomologous chromosomesomologous chromosomes come together to form a tetradtetrad. ∗TetradTetrad is two chromosomeschromosomes or four chromatidschromatids (sister and nonsister chromatids). Prophase IProphase I 3/11/2018Carolyn Joseph (16BCB0098) 10
  • 11. Homologous chromosomes sister chromatids paternal sister chromatids maternal Tetrad 3/11/2018Carolyn Joseph (16BCB0098) 11
  • 12. ∗ Crossing overCrossing over: segments of nonsister chromatidschromatids break and reattach to the other chromatidchromatid. ∗ Crossing overCrossing over causescauses variationvariation Prophase 1 – Crossing OverProphase 1 – Crossing Over 3/11/2018Carolyn Joseph (16BCB0098) 12
  • 13. Crossing Over - variationCrossing Over - variation nonsister chromatids chiasmata: site of crossing over variation Tetrad 3/11/2018Carolyn Joseph (16BCB0098) 13
  • 14. ∗ TetradsTetrads align on the in center of cell on spindle ∗ INDEPENDENT ASSORTMENT OCCURS:INDEPENDENT ASSORTMENT OCCURS: 1. Orientation of homologous pair to poles is random. 2. Variation Metaphase IMetaphase I OR 3/11/2018Carolyn Joseph (16BCB0098) 14
  • 15. ∗ Homologous chromosomesHomologous chromosomes separate and move towards the poles. ∗ Sister chromatidsSister chromatids remain attached at their centromerescentromeres. Anaphase IAnaphase I 3/11/2018Carolyn Joseph (16BCB0098) 15
  • 16. ∗ Each pole now has haploidhaploid set of chromosomeschromosomes. ∗ CytokinesisCytokinesis occurs and two haploid daughter cells are formed. Telophase ITelophase I 3/11/2018Carolyn Joseph (16BCB0098) 16
  • 17. ∗ No interphase IINo interphase II ∗ Remember:Remember: Meiosis IIMeiosis II is similar to mitosismitosis Meiosis IIMeiosis II 3/11/2018Carolyn Joseph (16BCB0098) 17
  • 18. ∗ same as prophaseprophase in mitosismitosis Prophase IIProphase II 3/11/2018Carolyn Joseph (16BCB0098) 18
  • 19. ∗ same as metaphasemetaphase in mitosismitosis Metaphase IIMetaphase II 3/11/2018Carolyn Joseph (16BCB0098) 19
  • 20. ∗ same as anaphaseanaphase in mitosismitosis ∗ sister chromatids separatesister chromatids separate Anaphase IIAnaphase II 3/11/2018Carolyn Joseph (16BCB0098) 20
  • 21. ∗ Four haploid daughter cells producedFour haploid daughter cells produced gametes = sperm or egggametes = sperm or egg Telophase IITelophase II 3/11/2018Carolyn Joseph (16BCB0098) 21