5. Amphipathic in nature (Both hydrophilic and
hydrophobic regions in the structure
All carbon atoms derived from acetyl coA
Acetyl coA provides all carbon atoms
Reducing equivalents are supplied by NADPH
ATP provides energy
6. For production of one molecule of
cholesterol, all of the following should be
available
18 moles of acetyl coA
36 moles of ATP
16 moles NADPH
7.
8. is a molecule that participates in many
biochemical reactions in protein,
carbohydrate and lipid metabolism.
Its main function is to deliver the acetyl group
to the citric acid cycle (Krebs cycle) to be
oxidized for energy production
9.
10. Major constituents of plasma membrane and
plasma lipoproteins
Precursor of bile salts
Precursor of steroid hormones
Precursor of vitamin D, cardiac glycosides
and some alkaloids
Required for nerve transmission. Widely
distributed in all cells of the body but
particularly abundant in nerve tissue
11. Too much cholesterol in blood stream which
is known as hypercholesterolemia accumulate
around the lining of arteries.
Together with other substances, it can form
plaque( thick, hard deposit that can narrow
the arteries and make them less flexible)
12. Atherosclerosis-The process of fatty
substances, cholesterol, cellular waste
products, calcium and fibrin( clotting material
in blood) building up in the inner lining of an
artery.
The build up that’s results is called plaque
13.
14. Heart disease
blood carries oxygen to our heart
Atherosclerosis reduces the amount of blood
flowing to our heart.
If blood stops flowing to the heart because of
a blockage in the arteries, a heart attack
occurs.
