Heavy metals are naturally occurring elements that have a high atomic weight and a density at least 5 times greater than that of water. Their multiple industrial, domestic, agricultural, medical and technological applications have led to their wide distribution in the environment; raising concerns over their potential effects on human health and the environment. Their toxicity depends on several factors including the dose, route of exposure, and chemical species, as well as the age, gender, genetics, and nutritional status of exposed individuals. Because of their high degree of toxicity, arsenic, cadmium, chromium, lead, and mercury rank among the priority metals that are of public health significance. Genetic Engineering is one of the best technique for the remediation of heavy metals.

2. •Introduction
•Reasons for Metal Remediation
•Advantages
•Genetically Engineered E.coli
•Poplar Plant Transformation
•Test of heavy metal resistance
•Conclusion

3. The introduction of desired gene
from another specie for desired trait
is called genetic engineering.

5. •To enhance the remediation process
•Safe way
•Cheap
•More Effective

6. Introduction of nix A gene from
Helicobacter pylori
E.coli

8. When grown in agar media
containing 0.1 and 0.3 mM of
CdCl2, the poplar plants which
express YCF1 grew much better than
the wild type plants did.

9. We continue to search for new genes with
different functions and stack them
introducing many genes into the same
line of plants or microbes, which will
hopefully further improve the plants or
microbs capacity to clean up the
environment.

10. Thank You