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Emerging Evidence in
Infection Control Effecting
Change

Melissa D. Machan, ARNP,CRNA
Background

Nosocomial infections cost hospitals a
great deal of money every year and affect
a large amount of patients admitted to the
hospital.
Nosocomial infections could potentially
result from visible and occult blood
present on reusable anesthetic airway
equipment.
It has been established that the current
methods for sterilizing and storing
reusable laryngoscope blades are
ineffective.
Background Continued
Intubation of the trachea has been a risky
cross-contamination procedure over the past
couple of decades because no perfect
decontamination procedure exists.
Disposable laryngoscope blades have been
made available to prevent potential cross
contamination while intubation of the trachea is
being performed.
These single use disposable laryngoscope
blades have come with mixed reviews from
anesthesia providers.
Purpose of the Project
The purpose of this evidence based project is to
determine the perceptions of anesthesia
providers regarding the use of a disposable
laryngoscope blade, their frequency of use, their
evaluation of ease of use, and any complications
encountered when using the disposable blade
before and after an in-service program designed
to increase use of disposable blades.
PICO Question

In patients requiring intubation (P), how does the
use of a disposable laryngoscope blade (I)
compared with a reusable laryngoscope blade
(C) affect ease of use, complications, and cost
(O)?
Research Questions
What is the perception of anesthesia providers
regarding ease of use, complications, and cost
of disposable laryngoscope blades before and
after the in-service program?
What percent of anesthesia providers use
disposable laryngoscope blades before and
after the in-service program?
How many disposable laryngoscope blades
were used in the facility in the 3-months before
and after the in-service program?
Research Questions
What is the anesthesia providers’ evaluation of
ease of use of the disposable laryngoscope
blade?
What are the providers’ rationales for non-use
of a disposable laryngoscope blade after the in-
service-program?
What complications did anesthesia providers
encounter when using a disposable
laryngoscope blade?
Studies Investigating the
     Presence of Visible and Occult
        Blood on Laryngoscope
          Blades and Handles
Author/Date        Design          Sample            Outcome       Interventions      Results         Limitations
Williams et al. Randomized      192 specimens      Assessed for    Laryngoscope    One or more       Inadequate
(2010)          blinded Study   from 64            bacterial       handles.        species of        sensitivity of
                                laryngoscope       contamination                   bacteria          the
                                handles            and occult                      were isolated     detection of
                                deemed „ready      blood.                          from 55(86%)      blood methods
                                for patient use‟                                   of the handles.   employed.
                                in the                                             No occult         Sites B and C
                                anesthetic                                         blood             were swabbed
                                rooms                                              contamination     for microbial
                                of 32                                              was               contamination
                                operating                                          demonstrated.     prior to
                                theatres.                                                            sampling for
                                                                                                     occult blood.
Studies Investigating the
     Presence of Visible and Occult
        Blood on Laryngoscope
          Blades and Handles
Author/Date      Design          Sample       Outcome     Interventions      Results          Limitations

Phillips &    Prospective     Sixty-five    Presence of   Visible and     None of the        Contamination
Monaghan      observational   laryngoscope occult blood   occult blood    blades or          could have
(1997)        study           blades and                  on              handles            happened after
                              handles                     laryngoscope    observed had       the
                              identified as               blades and      visible blood.     sterilization
                              ready for                   handles that    Of the 65
                              patient use                 were            blades tested
                              were observed               identified as   for occult
                              for visible                 ready for       blood, 10
                              blood and                   patient use     (20%) tested
                              tested for                                  positive. Of
                              occult blood                                the 65 handles
                                                                          tested for
                                                                          occult blood,
                                                                          26 (40%)
                                                                          tested positive.
Studies Investigating the
      Presence of Visible and Occult
         Blood on Laryngoscope
Author/DateBlades and Handles
Esler et al.
                  Design
               Questionnaire
                                  Sample
                               Of the 289
                                                Outcome
                                              Cleaning
                                                          Interventions
                                                          Survey
                                                                              Results
                                                                           One third of
                                                                                              Limitations
                                                                                             Conducted
(1999)                         questionnaires methods     methods of       the units the     outside the
                               sent out, 239              laryngoscope     handle is not     United States
                               were returned.             cleaning in      cleaned at all.
                                                          units through    Only 5%
                                                          Great Britain.   routinely
                                                                           autoclave the
                                                                           handle and in
                                                                           12% of the
                                                                           units,
                                                                           disposable
                                                                           laryngoscopes
                                                                           are used. One
                                                                           third would
                                                                           not be
                                                                           prepared to
                                                                           put a cleaned
                                                                           blade into
                                                                           their mouth.
Studies Investigating the Ease
         of Use of Disposable
         Laryngoscope Blades
Author/Date      Design          Sample         Outcome     Interventions      Results        Limitations

Anderson et   Randomized      32 anesthetists Ease of use   Standard        “Easy”           Although a
al. (2006)    unblindedstud   with between                  reusable        setting:         high-fidelity
              y               11 months and                 laryngoscope    laryngoscopy     patient
                              25 years of                   blades          more difficult   simulator
                              experience                                    with the         allows for
                              using a high-                 Standard        covered blade    standardized,
                              fidelity                      reusable        ( p= 0.001)      reproducible
                              simulator                     laryngoscope    and the          intubating
                                                            blades with     disposable       conditions
                                                            disposable      blades.          there is debate
                                                            blade covers    “Difficult”      as to whether
                                                                            setting:         it is an
                                                            Disposable      laryngoscopy     adequately
                                                            laryngoscope    more difficult   validated tool
                                                            blades          with both the    for assessment
                                                                            covered          of anesthetists.
                                                                            blades (22%,
                                                                            p=0.008)and
                                                                            the disposable
                                                                            blades (69%,
                                                                            p<0.001)
Studies Investigating the Ease
         of Use of Disposable
         Laryngoscope Blades
Author/Date        Design        Sample         Outcome     Interventions      Results         Limitations


Sudhir et al.   Manikin based 11 disposable   Ease of use   Disposable      Better user       Not blinded,
(2007)          observational and standard                  and standard    satisfaction      user bias
                study         re-usable                     re-usable       with metal
                              Miller size 1                 Miller size 1   disposable
                              blades                        blades          blades
                                                                            (p<0.001).
                                                                            Greater force
                                                                            needed with
                                                                            plastic blades.
Studies Investigating the Ease
         of Use of Disposable
         Laryngoscope Blades
Author/Date         Design          Sample          Outcome       Interventions       Results       Limitations

Rassam, et al.   Observational   Fifty            Ease of         One metal re-    Ease of         Not blinded,
(2005)           study           anesthetists     attachment of   usable           attachment,     user bias
                                 were recruited   the blade to    blade, five       illumination,
                                 to use 20        the handle;     metal single-    view, clinical
                                 different        illumination;   use blades and   use, force and
                                 laryngoscope     view of the     14 plastic       duration were
                                 blades (one      larynx; and     single-use       all
                                 metal re-        satisfaction    blades.          significantly
                                 usable           for clinical                     affected by the
                                 blade, five       use. The peak                    blade used (p
                                 metal single-    force applied                    < 0.0001 for
                                 use blades and   and time to                      all six). Two
                                 14 plastic       achieve the                      plastic blades
                                 single-use       grade I                          provided a
                                 blades.          Cormack and                      poor view and
                                                  Lehane view                      increased the
                                                  were also                        duration of
                                                  measured.                        laryngoscopy.
Studies Investigating Failed
         Intubation with Disposable
            Laryngoscope Blades
Author/Date        Design          Sample        Outcome    Interventions       Results       Limitations

Amour et al.   Randomized       1,072 adult    Failed       Single-use       Significantly   Not blinded
(2010)         clinical trial   patients       Intubation   metal            more failed
                                undergoing                  laryngoscope     intubation
                                general                     blade,           with reusable
                                anesthesia                  reusable metal   blades (5.4
                                under                       laryngoscope     versus 2.8%,
                                emergency                   blade            p<0.05).
                                conditions and
                                requiring
                                rapid
                                sequence
                                induction
                                (RSI).
Studies Investigating Failed
         Intubation with Disposable
            Laryngoscope Blades
Author/Date        Design          Sample        Outcome   Interventions        Results        Limitations


Amour et al.   Cluster          284 adult      Failed      Plastic single-   Significantly    Not blinded
(2006)         Randomized       patients were Intubation   use               more failed
               clinical trial   randomly                   laryngoscope      intubations on
                                assigned on a              blades, Metal     the first
                                weekly basis               reusable          attempt with
                                to either                  laryngoscope      the plastic
                                plastic single             blades            single use
                                use or                                       laryngoscope
                                reusable metal                               blade (17%
                                blades.                                      vs. 3%,
                                                                             p<0.01).
Studies Investigating Failed
          Intubation with Disposable
             Laryngoscope Blades
Author/Date          Design          Sample        Outcome    Interventions      Results      Limitations

Galinski et al.   Prospective     119            Failed       Vital View      Of the 119     Not blinded,
(2003)            observational   intubations    Intubation   disposable      first attempts user bias
                  study           were                        laryngoscope    using the
                                  perfumed                    blades          disposable
                                  using                                       blades only 12
                                  disposable                                  blade changes
                                  blades and                                  had to be
                                  100                                         performed
                                  intubations                                 before
                                  were                                        successful
                                  performed                                   intubation
                                  using
                                  traditional
                                  metal blades
                                  on the first
                                  attempt.
Studies Investigating Failed
         Intubation with Disposable
            Laryngoscope Blades
Author/Date         Design        Sample        Outcome    Interventions      Results        Limitations

Shahriari et al. Prospective   200 patients   Failed       Disposable      The              The
(2007)           study         that were      Intubation   laryngoscope    disposable       anesthetists
                               randomly                    blade and the   laryngoscope     had different
                               divided into                reusable        blade group      levels of
                               two groups.                 laryngoscope    had a 14%        experience
                                                           blade.          incidence of
                                                                           failed
                                                                           intubation and
                                                                           21% incidence
                                                                           of prolonged
                                                                           intubation.
Studies Investigating Failed
           Intubation with Disposable
Author/Date
              Laryngoscope Blades
                  Design          Sample        Outcome    Interventions     Results       Limitations

Jabre et al.   Observational   Intubated with Failed       Metallic blade The first-       Not blinded,
(2007)         before-and-     metallic       Intubation   plastic blade  attempt         user bias
               after study     blade(594/117                              intubation
                               7) and with a                              success rate
                               plastic blade                              was higher
                               (583/1177).                                in the metallic
                                                                          blade group.
                                                                          The incidence
                                                                          of difficult
                                                                          intubation was
                                                                          lower when
                                                                          metallic
                                                                          blades were
                                                                          used. A good
                                                                          laryngeal view
                                                                          was more
                                                                          frequently
                                                                          observed with
                                                                          metallic blade
                                                                          use.
Studies Investigating Flexibility
      and Light Emission of the
      Disposable Laryngoscope
Author/Date     Blade
                  Design          Sample          Outcome      Interventions      Results       Limitations

Goodwin et al. Observational   Eleven Miller    Flexibility and Disposable     There was a     No standard
(2006)         study           1 blades. 3      light emission and re-usable   significant     set as to the
                               new samples                      Miller 1       difference in   degree of
                               of each blade.                   Blades         flexibility     flexibility that
                                                                               between metal   is acceptable.
                                                                               and plastic
                                                                               blades
                                                                               (p=0.006). An
                                                                               eightfold
                                                                               difference in
                                                                               level of
                                                                               illumination
                                                                               provided.
Studies Investigating Flexibility
      and Light Emission of the
      Disposable Laryngoscope
Author/Date     Blade
                   Design          Sample        Outcome     Interventions       Results       Limitations


Cheung et al.   Observational   Fifty-one     Illumination   New Batteries,   Fourteen        All
(2007)          study           laryngoscopes                new bulb, new    percent of      measurements
                                                             batteries and    laryngoscopes   were made
                                                             new bulb, and    (7/51)          from one
                                                             attachment of    at baseline     ambulance
                                                             a disposable     met the         base. Results
                                                             blade            minimal         may not be
                                                                              illumination    generalizable.
                                                                              criterion.
Studies Investigating Cost,
    User Satisfaction and Provider
             Preference
Author/Date      Design       Sample      Outcome      Interventions      Results       Limitations


Romig, L.     Methodical   17 studies   Disposable     Cost, user      Decision to     EMS
(2008)        Problem                   laryngoscope   satisfaction,   transition to   practitioners
              analysis                  blades or      quality         disposable
                                        reusable       management,     equipment
                                        laryngoscope   risk
                                        blades         management
Studies Investigating Cost,
    User Satisfaction and Provider
Author/Date
             Preference
                 Design          Sample          Outcome      Interventions      Results       Limitations


Rowley        Survey, focus   Eight English    Quality and    Provider        Despite
&Dingwall     group and       NHS Trusts       efficacy of    preference      reservations
(2007)        interview       covering 12      single-use                     about induced
              methodologies   hospital sites   laryngoscope                   harm and the
              .               was selected.    blades                         unknown risk
                              Twenty-three                                    of an
                              interviews                                      iatrogenic
                              were                                            disease, most
                              completed.                                      clinicians
                                                                              would want
                                                                              single-use
                                                                              devices used
                                                                              on themselves
                                                                              and their
                                                                              family if they
                                                                              were patients.
Emerging Evidence on Disposable Laryngoscope Blades

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Emerging Evidence on Disposable Laryngoscope Blades

  • 1. Emerging Evidence in Infection Control Effecting Change Melissa D. Machan, ARNP,CRNA
  • 2. Background Nosocomial infections cost hospitals a great deal of money every year and affect a large amount of patients admitted to the hospital. Nosocomial infections could potentially result from visible and occult blood present on reusable anesthetic airway equipment. It has been established that the current methods for sterilizing and storing reusable laryngoscope blades are ineffective.
  • 3. Background Continued Intubation of the trachea has been a risky cross-contamination procedure over the past couple of decades because no perfect decontamination procedure exists. Disposable laryngoscope blades have been made available to prevent potential cross contamination while intubation of the trachea is being performed. These single use disposable laryngoscope blades have come with mixed reviews from anesthesia providers.
  • 4. Purpose of the Project The purpose of this evidence based project is to determine the perceptions of anesthesia providers regarding the use of a disposable laryngoscope blade, their frequency of use, their evaluation of ease of use, and any complications encountered when using the disposable blade before and after an in-service program designed to increase use of disposable blades.
  • 5. PICO Question In patients requiring intubation (P), how does the use of a disposable laryngoscope blade (I) compared with a reusable laryngoscope blade (C) affect ease of use, complications, and cost (O)?
  • 6. Research Questions What is the perception of anesthesia providers regarding ease of use, complications, and cost of disposable laryngoscope blades before and after the in-service program? What percent of anesthesia providers use disposable laryngoscope blades before and after the in-service program? How many disposable laryngoscope blades were used in the facility in the 3-months before and after the in-service program?
  • 7. Research Questions What is the anesthesia providers’ evaluation of ease of use of the disposable laryngoscope blade? What are the providers’ rationales for non-use of a disposable laryngoscope blade after the in- service-program? What complications did anesthesia providers encounter when using a disposable laryngoscope blade?
  • 8. Studies Investigating the Presence of Visible and Occult Blood on Laryngoscope Blades and Handles Author/Date Design Sample Outcome Interventions Results Limitations Williams et al. Randomized 192 specimens Assessed for Laryngoscope One or more Inadequate (2010) blinded Study from 64 bacterial handles. species of sensitivity of laryngoscope contamination bacteria the handles and occult were isolated detection of deemed „ready blood. from 55(86%) blood methods for patient use‟ of the handles. employed. in the No occult Sites B and C anesthetic blood were swabbed rooms contamination for microbial of 32 was contamination operating demonstrated. prior to theatres. sampling for occult blood.
  • 9. Studies Investigating the Presence of Visible and Occult Blood on Laryngoscope Blades and Handles Author/Date Design Sample Outcome Interventions Results Limitations Phillips & Prospective Sixty-five Presence of Visible and None of the Contamination Monaghan observational laryngoscope occult blood occult blood blades or could have (1997) study blades and on handles happened after handles laryngoscope observed had the identified as blades and visible blood. sterilization ready for handles that Of the 65 patient use were blades tested were observed identified as for occult for visible ready for blood, 10 blood and patient use (20%) tested tested for positive. Of occult blood the 65 handles tested for occult blood, 26 (40%) tested positive.
  • 10. Studies Investigating the Presence of Visible and Occult Blood on Laryngoscope Author/DateBlades and Handles Esler et al. Design Questionnaire Sample Of the 289 Outcome Cleaning Interventions Survey Results One third of Limitations Conducted (1999) questionnaires methods methods of the units the outside the sent out, 239 laryngoscope handle is not United States were returned. cleaning in cleaned at all. units through Only 5% Great Britain. routinely autoclave the handle and in 12% of the units, disposable laryngoscopes are used. One third would not be prepared to put a cleaned blade into their mouth.
  • 11. Studies Investigating the Ease of Use of Disposable Laryngoscope Blades Author/Date Design Sample Outcome Interventions Results Limitations Anderson et Randomized 32 anesthetists Ease of use Standard “Easy” Although a al. (2006) unblindedstud with between reusable setting: high-fidelity y 11 months and laryngoscope laryngoscopy patient 25 years of blades more difficult simulator experience with the allows for using a high- Standard covered blade standardized, fidelity reusable ( p= 0.001) reproducible simulator laryngoscope and the intubating blades with disposable conditions disposable blades. there is debate blade covers “Difficult” as to whether setting: it is an Disposable laryngoscopy adequately laryngoscope more difficult validated tool blades with both the for assessment covered of anesthetists. blades (22%, p=0.008)and the disposable blades (69%, p<0.001)
  • 12. Studies Investigating the Ease of Use of Disposable Laryngoscope Blades Author/Date Design Sample Outcome Interventions Results Limitations Sudhir et al. Manikin based 11 disposable Ease of use Disposable Better user Not blinded, (2007) observational and standard and standard satisfaction user bias study re-usable re-usable with metal Miller size 1 Miller size 1 disposable blades blades blades (p<0.001). Greater force needed with plastic blades.
  • 13. Studies Investigating the Ease of Use of Disposable Laryngoscope Blades Author/Date Design Sample Outcome Interventions Results Limitations Rassam, et al. Observational Fifty Ease of One metal re- Ease of Not blinded, (2005) study anesthetists attachment of usable attachment, user bias were recruited the blade to blade, five illumination, to use 20 the handle; metal single- view, clinical different illumination; use blades and use, force and laryngoscope view of the 14 plastic duration were blades (one larynx; and single-use all metal re- satisfaction blades. significantly usable for clinical affected by the blade, five use. The peak blade used (p metal single- force applied < 0.0001 for use blades and and time to all six). Two 14 plastic achieve the plastic blades single-use grade I provided a blades. Cormack and poor view and Lehane view increased the were also duration of measured. laryngoscopy.
  • 14. Studies Investigating Failed Intubation with Disposable Laryngoscope Blades Author/Date Design Sample Outcome Interventions Results Limitations Amour et al. Randomized 1,072 adult Failed Single-use Significantly Not blinded (2010) clinical trial patients Intubation metal more failed undergoing laryngoscope intubation general blade, with reusable anesthesia reusable metal blades (5.4 under laryngoscope versus 2.8%, emergency blade p<0.05). conditions and requiring rapid sequence induction (RSI).
  • 15. Studies Investigating Failed Intubation with Disposable Laryngoscope Blades Author/Date Design Sample Outcome Interventions Results Limitations Amour et al. Cluster 284 adult Failed Plastic single- Significantly Not blinded (2006) Randomized patients were Intubation use more failed clinical trial randomly laryngoscope intubations on assigned on a blades, Metal the first weekly basis reusable attempt with to either laryngoscope the plastic plastic single blades single use use or laryngoscope reusable metal blade (17% blades. vs. 3%, p<0.01).
  • 16. Studies Investigating Failed Intubation with Disposable Laryngoscope Blades Author/Date Design Sample Outcome Interventions Results Limitations Galinski et al. Prospective 119 Failed Vital View Of the 119 Not blinded, (2003) observational intubations Intubation disposable first attempts user bias study were laryngoscope using the perfumed blades disposable using blades only 12 disposable blade changes blades and had to be 100 performed intubations before were successful performed intubation using traditional metal blades on the first attempt.
  • 17. Studies Investigating Failed Intubation with Disposable Laryngoscope Blades Author/Date Design Sample Outcome Interventions Results Limitations Shahriari et al. Prospective 200 patients Failed Disposable The The (2007) study that were Intubation laryngoscope disposable anesthetists randomly blade and the laryngoscope had different divided into reusable blade group levels of two groups. laryngoscope had a 14% experience blade. incidence of failed intubation and 21% incidence of prolonged intubation.
  • 18. Studies Investigating Failed Intubation with Disposable Author/Date Laryngoscope Blades Design Sample Outcome Interventions Results Limitations Jabre et al. Observational Intubated with Failed Metallic blade The first- Not blinded, (2007) before-and- metallic Intubation plastic blade attempt user bias after study blade(594/117 intubation 7) and with a success rate plastic blade was higher (583/1177). in the metallic blade group. The incidence of difficult intubation was lower when metallic blades were used. A good laryngeal view was more frequently observed with metallic blade use.
  • 19. Studies Investigating Flexibility and Light Emission of the Disposable Laryngoscope Author/Date Blade Design Sample Outcome Interventions Results Limitations Goodwin et al. Observational Eleven Miller Flexibility and Disposable There was a No standard (2006) study 1 blades. 3 light emission and re-usable significant set as to the new samples Miller 1 difference in degree of of each blade. Blades flexibility flexibility that between metal is acceptable. and plastic blades (p=0.006). An eightfold difference in level of illumination provided.
  • 20. Studies Investigating Flexibility and Light Emission of the Disposable Laryngoscope Author/Date Blade Design Sample Outcome Interventions Results Limitations Cheung et al. Observational Fifty-one Illumination New Batteries, Fourteen All (2007) study laryngoscopes new bulb, new percent of measurements batteries and laryngoscopes were made new bulb, and (7/51) from one attachment of at baseline ambulance a disposable met the base. Results blade minimal may not be illumination generalizable. criterion.
  • 21. Studies Investigating Cost, User Satisfaction and Provider Preference Author/Date Design Sample Outcome Interventions Results Limitations Romig, L. Methodical 17 studies Disposable Cost, user Decision to EMS (2008) Problem laryngoscope satisfaction, transition to practitioners analysis blades or quality disposable reusable management, equipment laryngoscope risk blades management
  • 22. Studies Investigating Cost, User Satisfaction and Provider Author/Date Preference Design Sample Outcome Interventions Results Limitations Rowley Survey, focus Eight English Quality and Provider Despite &Dingwall group and NHS Trusts efficacy of preference reservations (2007) interview covering 12 single-use about induced methodologies hospital sites laryngoscope harm and the . was selected. blades unknown risk Twenty-three of an interviews iatrogenic were disease, most completed. clinicians would want single-use devices used on themselves and their family if they were patients.