This document summarizes a webinar on the changing face of canine pyoderma (bacterial skin infections in dogs) and strategies for control. It discusses why dogs are prone to pyoderma due to defective natural defenses. It also covers classification of pyoderma, clinical signs, diagnosis, treatment including antibiotics and alternatives, and problems with antibiotic resistance. The webinar aims to educate veterinarians on pyoderma identification, treatment, and prevention of further resistance issues.
5. What we are covering this afternoon
• Why is the dog a pyoderma waiting to happen?
• Classification of pyoderma
• Clinical signs
• Diagnosis of pyoderma- ddx
• Treatment
• Problems with resistance
8. A Pathogenic Staphylococcus
• S pseudintermedius
• Bacteria produces a variety of substances including
enterotoxins, toxic shock protein, protein A and haemolysins
• Increase adhesion to keratinocytes
• Act as superantigens and upregulate the immunological
responses
• Some strains produce slime which encapsulate the bacteria
and inhibit phagocytosis whilst increasing its ability to adhere
36. Cefovecin
• Can increase compliance
• But sub-optimal levels of antibiotic after the 2 weeks
• Is a 3rd generation cephalosporin
37. Staphage lysate
• Stimulates both humoral and cellular immunity
• 1 study showed 77% of dogs had significant
benefits
38. Autogenous vaccines
• Prepared individually for each dog from a culture
• Given with antibiotics and then weaned off
antibiotics
• Speak to RVC
• Particularly useful in cases of recurrent idiopathic
pyoderma
51. MRSA and MRSP
How often have you seen a resistant case this year
• 0
• 1-2
• 3-5
• 6-10
• More than 10
52. Methicillin resistance
• First reported in 1960s
• Due to a mecA gene encoding an altered PBP
• S aureus human pathogen
• S pseudintermedius companion animal pathogen
• More of a problem in USA and Europe but coming
53. How can we prevent
• Better hygiene in the practice.
• Use less antibiotics where possible.
• Higher doses and for longer times.
• Use appropriate antibiotic for pyoderma.
• Teach compliance.
• Don’t use corticosteroids at the same time
54. Do you use something milky for your cat speys?
• Yes
• No
55. Thanks
• David Lloyd
• Tony Liepman at Animalcare
• You for listening