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FUNCTIONAL ANATOMY
OF EYE;OPTICS OF EYE
& REFRACTIVE ERRORS
DR.K.AMUDHA LAKSHMI M.B.B.S.,D.O.,M.D
SYNOPSIS
 INTRODUCTION
 HISTORY
 STRUCTURE OF EYEBALL
OPTICS OF EYE
REFRACTIVE ERRORS
 APPLIED ASPECTS
INTRODUCTION
 Vision- important special sense
 Performed by eye balls
 Situated in a quadrilateral pyramid shaped bony
cavity- orbit
 Well protected by eyelids and extraocular
muscles
There are some species in animal
kingdom which doesn’t have eyes to see
SEA URCHINS
MEXICAN TETRA FISH
HISTORY
A.D. Galen – Retina
 Euclid – Geometrical optics
 Benjamin Franklin – Spectacles
 Leonardo Da Vinci – Lens
 Thomas Young, Von Helmholtz - Color vision
STRUCTURE OF EYEBALL
EYE DEVELOPMENT
Begins at 3 weeks & continues upto 10 weeks.
 Derived from neuroepithelium, surface
ectoderm, neural crest and mesoderm.
Neuroepithelium - retina, ciliary body, iris,
optic nerve.
Surface ectoderm- lens, corneal epithelium,
eyelid.
Extra cellular mesenchyme- sclera, cornea,
blood vessels, muscles, and vitreous.
STRUCTURE OF EYEBALL
 The anteroposterior diameter- 24 mm
 Volume : 6.5 ml
 Weight : 7 g
Shape- oblate spheroid
 It has 3 layers :
Outer- fibrous sclera and cornea
Middle- uveal tract- vascular and
pigmented
Inner – retina- nervous coat
APPENDAGES OF EYE
Limbus
Sclerocorneal junction
Anterior chamber
2.5 mm deep
0.25 ml of aqueous humor
Posterior chamber
0.06 ml of aqueous humor
Posterior cavity
Vitreous humor
Sclera
Avascular fibrous coat
Gives protection for eyeball contents
Bulbar conjunctiva
Palpebral conjunctiva
Conjunctivitis
Cornea
Avascular
Transparent
More convex
Trigerminal nerve
The average diameter 11 – 12 mm
Thickness center 0.52 mm
periphery 0.67 mm
Has 5 layers
Epithelium
Stratified squamous
Highly proliferative
Regenerate & heal rapidly
Bowman’s membrane
Heals with a scar
Stroma
Collagen fibrils
90% of thickness
Descemet’s membrane
Resistant to infection
Can regenerate
Endothelium
Prevents excess hydration of cornea
Keratitis
Corneal abrasion
Corneal ulcer
Corneal transplant-most successful one
Lacrimal gland
Secretes tear
Keeps cornea moistened
Contain lysozymes, antibodies
Blinking- spread tears
Basal secretion-1ml in 24 hrs
Regulation of stromal water-
clarity of vision
Choroid
Lines the inner aspect of sclera
Provide nourishment to eye structures
Membrane of bruch- inner side
Supra choroidal space-b/w choroid & sclera
Chromatophores
Albinism
Choroiditis
Choroidal detachment
Ciliary body
Ciliary muscle & ciliary processes
Ciliary muscle-meridional,radial & circular
Ciliary body attaches to suspensory
ligaments
Ciliary processes secrete aqueous humor
Cyclitis
Iris
Characteristic colour to eye
Central aperture- Pupil
Highly vascular
Circular & radial muscles
Myosis-circular muscle- sphincter pupillae-
parasympathetic-occulomotor nerve
Mydriasis-radial muscle- dilator pupillae-
sympathetic- cervical sympathetic chain
remember- MaRS
Intrinsic muscles of
eye
Ciliary & iris muscles
Aqueous humor
Protein free clear fluid
Source-ciliary process
Ultrafiltration, diffusion,
active transport
Nutrient for lens & cornea
Rich in ascorbic acid
Formed in posterior
chamber poured into
anterior chamber
through pupil
Maintains IOP
Absorbed by trabecular
meshwork & drained into
schlemn canal
Open angle glaucoma
Closed angle glaucoma
Lens
Biconvex
Avascular
Highly elastic-collagen
fibrils
Converge light rays &
focus on retina
Protein- alpha crystalline
At rest- lens ligaments
stretched- anterior
surface is less convex
Opacity of lens- cataract-
immature /mature
Absence of lens- aphakia
Vitreous humor
Gelatinous
Transparent avascular
Protein- vitrein
Old age & high myopia-
liquefied
Persistent hyaloid artery
Retina
Very thin- 200 μm
10 layers, from outer to inner
1.Layer of pigment epithelium
2. Layer of rods and cones
3. External limiting membrane
4. Outer nuclear layer
5. Outer plexiform layer
6. Inner nuclear layer
7. Inner plexiform layer
8. Layer of ganglion cells
9. Layer of nerve fibers
10. Internal limiting membrane.
Surrounds the vitreous
Terminates at ora serrata
Pigment epithelium
Rich in melanocytes
Prevents scattering of light
Phagocytosis
Store vitamin A
Albinism- lack of melanin
Nystagmus, photophobia, defective vision
Cells in retina
Rods- 120 million
Cones- 6 million
Ganglion cells- 1 million
Horizontal cells- connect rods & cones
Bipolar cells-connects photoreceptors &
ganglion cells
Amacrine cells- connects bipolar cells &
ganglion cells
Retinal glial cells/ Muller cells- supporting
cells
Diabetic retinopathy
Retinal detachment
Retrolental fibroplasia/ Retinopathy of Prematurity
(ROP)
Macula lutea
Yellow spot
1-2 mm
Fovea centralis
0.4 mm
Only cones
Maximum visual acuity
Ratio of ganglion to cone cell 1:1
Optic disc
3mm medial to & above
posterior pole
No photoreceptors
Blind spot- at temporal
visual field
White in colour-
myelinated nerves
Fundus
Red background
Arteries readily visible
Diagnosing
HT,DM,atherosclerosis
IOP
10-20 mm Hg
Maintains shape of eyeball
Tonometry
Glaucoma
Extraocular muscles (LR 6 SO 4 O 3)
OPTICS OF EYE
PRINCIPLE OF REFRACTION
OPTICS OF EYE
Image formed on retina by
Refraction of light rays by
cornea and lens
Ciliary muscle activity-
accommodation of lens
Change in pupil size by iris
muscles
Principal axis of the lens
The line joining the centers of the two lens
surfaces
Optical center/ Nodal point of lens
Point on the principal axis through which
light rays pass without being deviated.
7 mm behind anterior surface of cornea
Principal focus
When parallel rays
of light strike the surface
of the lens, they
converge to meet at a
point behind the lens
Focal distance
The distance
between the optical
center of a lens and the
principal focus
The refractive power of lens
It is the reciprocal of the focal distance
of a lens in meters.
expressed in diopters (D)
greater the lens curvature, greater the
refractive power
Refraction takes place at
cornea
both surfaces of the lens
Total refractive power of eye = 60 D
43 D by cornea
17 D by lens
When the head is immersed in water, the
refractive power by cornea= zero, since water
has the same refractive index as cornea.
Schematic eye/reduced eye
Nodal point 7mm
Eyeball length=24 mm
Focal length=24-7
=17
Refractive power of lens= 1
Focal length( in metres)
=1000
17
=59 D
On retina
real
Inverted
Small image
Left to right reversal of image
In brain
Neural processing helps the brain to
perceive visual images in upright position.
ACCOMMODATION
Accommodation
Cornea-fixed structure
Normal resting eye- ciliary muscle relaxed
During accommodation
Ciliary muscle contracts
Suspensory ligaments relax
Lens becomes more convex
Visual axis converges
Pupil constricts
To focus an object present within 6
m, the eye has to increase its refractive
power, a process called accommodation,
in which the curvature of the lens is
increased.
Near point- The nearest point to the eye, at
which an object can be clearly seen
The maximum accommodation ability
of the eye decreases throughout life
lens-harder, progressive loss of
elasticity.
Chromatic aberrations
Long wavelength(red)-refracted
more
Short wavelength(violet)-refracted
less
Lights of different colours focussed
at different points on retina
Spherical aberrations
Non uniform refractive index of lens
Periphery-refraction more
Size of pupil
decreases chromatic and spherical
aberration by eliminating the peripheral
rays
increases the depth of focus
Bright light-pupil constricts-2 mm
Dark- pupil dilates- 8 mm
ERRORS OF REFRACTION
Emmetropia
The refractive condition of a normal
eye, in which the parallel rays of light from
a distant object are focused on the retina
without accommodation
Emmetropic eye
Ametropia
If the refractive state differs from the
normal, in which parallel rays are focused
in front or behind the retina resulting in a
blurred image.
Amblyopia ex anopsia
Occurs in children, one of the image is
suppressed, causing loss of vision in one
eye.
STRABISMUS/ SQUINT
Ametropia is of three types
Myopia
Hypermetropia
Astigmatism
May be due to abnormality in
Axial length of the eye
Refractive power − Curvature of the
surface of the cornea or the lens
Refractive indices of the media
Position of the lens
Myopia/ Short sightedness
A refractive error in which parallel rays of light
from a distant object are brought into a focus in
front of the retina when the accommodation is at
rest
Causes
Genetic
Acquired
More close work
AP diameter of eye increased
Correction
Biconcave lens- minus lens
Hypermetropia (Far-sightedness)
A refractive error in which parallel rays
of light from a distant object are brought into a
focus behind the retina when the
accommodation is at rest
Decreased anteroposterior diameter of
the eye
Correction
Biconvex lens- plus lens
Astigmatism
A refractive error in
which parallel rays of light
from a distant object
cannot converge to a
point focus on the retina
due to unequal
refraction at different
meridians.
Causes
Corneal surface is not perfectly
spherical, the curvature of one meridian
differs from the other.
Light rays are focused at different
points on the retina causing blurring of
image.
Lens curvature- not uniform or lens-
pushed out of alignment.
Correction- Cylindrical lens.
Presbyopia
Near point of vision recedes beyond the normal
reading or working distance due to progressive loss
of plasticity of the lens
Physiological phenomenon
Above 40 years
Normal Near point of accommodation 25-33 cm
Correction
Convex lens-plus lens
For both distant & near vision
Bifocal lens
SUMMARY
EYE ANATOMY
Anatomy, optics & refractive errors of eye

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Anatomy, optics & refractive errors of eye

  • 1. FUNCTIONAL ANATOMY OF EYE;OPTICS OF EYE & REFRACTIVE ERRORS DR.K.AMUDHA LAKSHMI M.B.B.S.,D.O.,M.D
  • 2. SYNOPSIS  INTRODUCTION  HISTORY  STRUCTURE OF EYEBALL OPTICS OF EYE REFRACTIVE ERRORS  APPLIED ASPECTS
  • 3. INTRODUCTION  Vision- important special sense  Performed by eye balls  Situated in a quadrilateral pyramid shaped bony cavity- orbit  Well protected by eyelids and extraocular muscles
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  • 5. There are some species in animal kingdom which doesn’t have eyes to see
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  • 10. HISTORY A.D. Galen – Retina  Euclid – Geometrical optics  Benjamin Franklin – Spectacles  Leonardo Da Vinci – Lens  Thomas Young, Von Helmholtz - Color vision
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  • 16. EYE DEVELOPMENT Begins at 3 weeks & continues upto 10 weeks.  Derived from neuroepithelium, surface ectoderm, neural crest and mesoderm. Neuroepithelium - retina, ciliary body, iris, optic nerve. Surface ectoderm- lens, corneal epithelium, eyelid. Extra cellular mesenchyme- sclera, cornea, blood vessels, muscles, and vitreous.
  • 17. STRUCTURE OF EYEBALL  The anteroposterior diameter- 24 mm  Volume : 6.5 ml  Weight : 7 g Shape- oblate spheroid  It has 3 layers : Outer- fibrous sclera and cornea Middle- uveal tract- vascular and pigmented Inner – retina- nervous coat
  • 19. Limbus Sclerocorneal junction Anterior chamber 2.5 mm deep 0.25 ml of aqueous humor Posterior chamber 0.06 ml of aqueous humor Posterior cavity Vitreous humor
  • 20. Sclera Avascular fibrous coat Gives protection for eyeball contents Bulbar conjunctiva Palpebral conjunctiva Conjunctivitis Cornea Avascular Transparent More convex Trigerminal nerve
  • 21.
  • 22. The average diameter 11 – 12 mm Thickness center 0.52 mm periphery 0.67 mm Has 5 layers Epithelium Stratified squamous Highly proliferative Regenerate & heal rapidly Bowman’s membrane Heals with a scar Stroma Collagen fibrils 90% of thickness
  • 23. Descemet’s membrane Resistant to infection Can regenerate Endothelium Prevents excess hydration of cornea Keratitis Corneal abrasion Corneal ulcer Corneal transplant-most successful one
  • 24. Lacrimal gland Secretes tear Keeps cornea moistened Contain lysozymes, antibodies Blinking- spread tears Basal secretion-1ml in 24 hrs Regulation of stromal water- clarity of vision
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  • 26. Choroid Lines the inner aspect of sclera Provide nourishment to eye structures Membrane of bruch- inner side Supra choroidal space-b/w choroid & sclera Chromatophores Albinism Choroiditis Choroidal detachment
  • 27. Ciliary body Ciliary muscle & ciliary processes Ciliary muscle-meridional,radial & circular Ciliary body attaches to suspensory ligaments Ciliary processes secrete aqueous humor Cyclitis
  • 28. Iris Characteristic colour to eye Central aperture- Pupil Highly vascular Circular & radial muscles Myosis-circular muscle- sphincter pupillae- parasympathetic-occulomotor nerve Mydriasis-radial muscle- dilator pupillae- sympathetic- cervical sympathetic chain remember- MaRS
  • 30. Aqueous humor Protein free clear fluid Source-ciliary process Ultrafiltration, diffusion, active transport Nutrient for lens & cornea Rich in ascorbic acid Formed in posterior chamber poured into anterior chamber through pupil
  • 31. Maintains IOP Absorbed by trabecular meshwork & drained into schlemn canal Open angle glaucoma Closed angle glaucoma Lens Biconvex Avascular Highly elastic-collagen fibrils Converge light rays & focus on retina
  • 32. Protein- alpha crystalline At rest- lens ligaments stretched- anterior surface is less convex Opacity of lens- cataract- immature /mature Absence of lens- aphakia
  • 33. Vitreous humor Gelatinous Transparent avascular Protein- vitrein Old age & high myopia- liquefied Persistent hyaloid artery
  • 34. Retina Very thin- 200 μm 10 layers, from outer to inner 1.Layer of pigment epithelium 2. Layer of rods and cones 3. External limiting membrane 4. Outer nuclear layer 5. Outer plexiform layer 6. Inner nuclear layer 7. Inner plexiform layer 8. Layer of ganglion cells 9. Layer of nerve fibers 10. Internal limiting membrane.
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  • 36. Surrounds the vitreous Terminates at ora serrata Pigment epithelium Rich in melanocytes Prevents scattering of light Phagocytosis Store vitamin A Albinism- lack of melanin Nystagmus, photophobia, defective vision
  • 37. Cells in retina Rods- 120 million Cones- 6 million Ganglion cells- 1 million Horizontal cells- connect rods & cones Bipolar cells-connects photoreceptors & ganglion cells Amacrine cells- connects bipolar cells & ganglion cells Retinal glial cells/ Muller cells- supporting cells
  • 38. Diabetic retinopathy Retinal detachment Retrolental fibroplasia/ Retinopathy of Prematurity (ROP) Macula lutea Yellow spot 1-2 mm Fovea centralis 0.4 mm Only cones Maximum visual acuity Ratio of ganglion to cone cell 1:1
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  • 40. Optic disc 3mm medial to & above posterior pole No photoreceptors Blind spot- at temporal visual field White in colour- myelinated nerves Fundus Red background Arteries readily visible Diagnosing HT,DM,atherosclerosis
  • 41. IOP 10-20 mm Hg Maintains shape of eyeball Tonometry Glaucoma
  • 42. Extraocular muscles (LR 6 SO 4 O 3)
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  • 51. OPTICS OF EYE Image formed on retina by Refraction of light rays by cornea and lens Ciliary muscle activity- accommodation of lens Change in pupil size by iris muscles
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  • 54. Principal axis of the lens The line joining the centers of the two lens surfaces Optical center/ Nodal point of lens Point on the principal axis through which light rays pass without being deviated. 7 mm behind anterior surface of cornea
  • 55. Principal focus When parallel rays of light strike the surface of the lens, they converge to meet at a point behind the lens Focal distance The distance between the optical center of a lens and the principal focus
  • 56. The refractive power of lens It is the reciprocal of the focal distance of a lens in meters. expressed in diopters (D) greater the lens curvature, greater the refractive power Refraction takes place at cornea both surfaces of the lens Total refractive power of eye = 60 D 43 D by cornea 17 D by lens
  • 57. When the head is immersed in water, the refractive power by cornea= zero, since water has the same refractive index as cornea. Schematic eye/reduced eye Nodal point 7mm Eyeball length=24 mm Focal length=24-7 =17 Refractive power of lens= 1 Focal length( in metres) =1000 17 =59 D
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  • 59. On retina real Inverted Small image Left to right reversal of image In brain Neural processing helps the brain to perceive visual images in upright position.
  • 61. Accommodation Cornea-fixed structure Normal resting eye- ciliary muscle relaxed During accommodation Ciliary muscle contracts Suspensory ligaments relax Lens becomes more convex Visual axis converges Pupil constricts
  • 62. To focus an object present within 6 m, the eye has to increase its refractive power, a process called accommodation, in which the curvature of the lens is increased. Near point- The nearest point to the eye, at which an object can be clearly seen The maximum accommodation ability of the eye decreases throughout life lens-harder, progressive loss of elasticity.
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  • 65. Chromatic aberrations Long wavelength(red)-refracted more Short wavelength(violet)-refracted less Lights of different colours focussed at different points on retina Spherical aberrations Non uniform refractive index of lens Periphery-refraction more
  • 66. Size of pupil decreases chromatic and spherical aberration by eliminating the peripheral rays increases the depth of focus Bright light-pupil constricts-2 mm Dark- pupil dilates- 8 mm
  • 67. ERRORS OF REFRACTION Emmetropia The refractive condition of a normal eye, in which the parallel rays of light from a distant object are focused on the retina without accommodation Emmetropic eye Ametropia If the refractive state differs from the normal, in which parallel rays are focused in front or behind the retina resulting in a blurred image.
  • 68. Amblyopia ex anopsia Occurs in children, one of the image is suppressed, causing loss of vision in one eye. STRABISMUS/ SQUINT
  • 69. Ametropia is of three types Myopia Hypermetropia Astigmatism May be due to abnormality in Axial length of the eye Refractive power − Curvature of the surface of the cornea or the lens Refractive indices of the media Position of the lens
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  • 71. Myopia/ Short sightedness A refractive error in which parallel rays of light from a distant object are brought into a focus in front of the retina when the accommodation is at rest Causes Genetic Acquired More close work AP diameter of eye increased Correction Biconcave lens- minus lens
  • 72. Hypermetropia (Far-sightedness) A refractive error in which parallel rays of light from a distant object are brought into a focus behind the retina when the accommodation is at rest Decreased anteroposterior diameter of the eye Correction Biconvex lens- plus lens
  • 73. Astigmatism A refractive error in which parallel rays of light from a distant object cannot converge to a point focus on the retina due to unequal refraction at different meridians.
  • 74.
  • 75. Causes Corneal surface is not perfectly spherical, the curvature of one meridian differs from the other. Light rays are focused at different points on the retina causing blurring of image. Lens curvature- not uniform or lens- pushed out of alignment. Correction- Cylindrical lens.
  • 76. Presbyopia Near point of vision recedes beyond the normal reading or working distance due to progressive loss of plasticity of the lens Physiological phenomenon Above 40 years Normal Near point of accommodation 25-33 cm Correction Convex lens-plus lens For both distant & near vision Bifocal lens
  • 77.