Gas gangrene by Dr.AmrithaAnilkumar
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Gas gangrene is an infective gangrene caused by clostridial organisms involving mainly skeletal muscle as oedematous myonecrosis.
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Gas gangrene by Dr.AmrithaAnilkumar
- 1. en love da Homoeopathy GAS GANGRENE
- 2. GAS GANGRENE
- 3. GAS GANRENE Definition • It is an infective gangrene caused by clostridial organisms involving mainly skeletal muscle as oedematousmyonecrosis.
- 4. PREDISPOSINGFACTORS • Contaminated, manured or cultivated soil • crushwounds • road trafficaccidents • after amputations • ischaemiclimb • necrosis • Anaerobicenvironments • clostridial sepsis
- 5. ORGANISMS • ClostridiumWelchii (perfringens) • Clostridiumoedematiens. • Clostridiumsepticum. • Clostridiumhistolyticum ORGANISMPRODUCING TOXINS™ • Alpha (most common)™ • Beta ™ • Epsilon™ • Exotoxins • Lecithinase- haemolytic, membranolyticand necrotic
- 6. EFFECTSOF TOXINS • Extensive necrosis brown or black anaerobic • myositis/myonecrosis. • affects the liver— foaming liver • Limbs are commonly involved INCUBATIONPERIOD • Incubationperiod is 1–2 days. CLINICALFEATURES • Toxaemia, • Fever • Tachycardia • Pallor • Foul smelling discharge (sicklysweaty/decaying apple odour). • Khaki brown coloured skin • Crepitus • Jaundice
- 7. CLINICALTYPES Fulminanttype- causes • toxaemia, • renal failure • Liver failure • MODS • ARDS. Massive type • fully dark coloured gas filled areas. Group type • Infectionof one group of muscles Single muscle type • affecting one single muscle. Subcutaneous type • involves only subcutaneous tissue COMPLICATION™ • Septicaemia • Toxaemia • Renal failure • Liver failure. • Circulatoryfailure • DIC
- 8. INVESTIGATIONS • X-ray • Liver function tests • Blood urea • Serumcreatinine • Total count, PO2, PCO2. • Robertson’s cooked meat media is used whichcauses meat to turn pinkwithsour smell and acidreaction • ClostridiumWelchii is grownin culturemedia & In the other half part of the platewhere there is antitoxinthere is no opacity—Nagler reaction.
- 9. TREATMENT • Antibiotic& Hyperbaricoxygen is very useful. • Amputationlife-saving procedure—stump should never be closed REFERENCE 1. SRB's Manual of Surgery by SriramBhatM 2. A Manual on Clinical Surgeryby Das 3. A Concise textbookof Surgeryby Das
- 10. A Special Thanks To A Very Special Doctor