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Submitted by-
Ajay Kumar Yadav
MSc Previous(zoology)
Submitted to-
Mr.rajneesh mishra
HOD ZOOLOGY
STEM CELL
 CONCEPT
 Major types of stem cell.
 Source of mature stem cells.
 Characterstics
 History of stem cell.
 Therapies
 Advantages
 Disadvantages
 Reference
 A Stem cell is an
undifferentiated
dividing cell that
gives rise to
daughter cell like
itself and a daughter
cell that becomes a
specialized cell type.
 Unspecialized cells.
 Give rise to more
than 225
specialized cells in
the body.
 Serve as the body`s
repair system.
-Renew itself
- Replenish other
cells.
Mature stem cells
 Adult cells includes
umbillical cord &
placenta.
 Cells obtained from
specific mature body
tissues, umbilical cord,
placenta.
 Multipotent- Give rise to
multiple but limited cell
types.
 Embryonic; includes
blastocystic.
 Cells obtained from
inner cell mass of a
blastocyst.
 Pluripotent- Flexible,
give rise to any cell type
in the body.
Early stem cells
MatureBody tissues
 who did it first?
 - In 1998, U.
Wisconsin
research team
isolates stem cells
from IVF-
blastocysts.
 Early stem cells
are pluripotent.
 Retain the special
ability to develop
into nearly any
cell type.
 Teratoma
 1998- James Thomson`s lab isolates the first human
embryonic stem cells.
 1999- First successful human transplant of insulin
making cells from cadavers.
 2000- president Bill Clinton allowed funding of
reasearch on cells derived from aborted human
fetuses, but not from embryonic cells.
 2001- President bush restricts federal funding for
embryonic stem cell research.
 2004- ballot measures for $3 billion bond for stem
cells.
 STEM CELL therapy is the use of stem cell to
treat or prevent a disease or condition. Bone
marrow transplant is a form of stem cell
therapy that has been used for many years
because it has proven to be effective in clinical
trails.
 Stem cell implantation may help in
strengthening the left ventricle of the heart, as
well as retaining the heart tissues to patients
who have suffered from heart attacks in the
past.
 Stem cell treatment may lower the symptoms
of the disease or condition that is being
treated.
 The lowering of symptoms may allow patients
to reduce the drug intake of the disease or
condition.
 Stem cell treatment may also provide
knowledge for society to further stem cell
understanding and future treatments.
 Ome may prevent the danger of surgical
interventions using stem cell.
 STEM CELL treatment may require
immunosuppression because of a requirement for
radiation before the transplant to remove the person`s
previous cells.
 Stem cell could also form tumors after transplantation.
 Harvesting cells from blastocyst result in death of the
blastocyst.
 Pluripotency in certain cells could also make it difficult
to obtain the exact cell type needed.
 TEXTBOOK
 WWW.SLIDESHARE.COM
 WIKIPEDIA
AJAY YADAV ppt of stem cell.pptx

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AJAY YADAV ppt of stem cell.pptx

  • 1. Submitted by- Ajay Kumar Yadav MSc Previous(zoology) Submitted to- Mr.rajneesh mishra HOD ZOOLOGY STEM CELL
  • 2.  CONCEPT  Major types of stem cell.  Source of mature stem cells.  Characterstics  History of stem cell.  Therapies  Advantages  Disadvantages  Reference
  • 3.  A Stem cell is an undifferentiated dividing cell that gives rise to daughter cell like itself and a daughter cell that becomes a specialized cell type.
  • 4.  Unspecialized cells.  Give rise to more than 225 specialized cells in the body.  Serve as the body`s repair system. -Renew itself - Replenish other cells.
  • 5. Mature stem cells  Adult cells includes umbillical cord & placenta.  Cells obtained from specific mature body tissues, umbilical cord, placenta.  Multipotent- Give rise to multiple but limited cell types.  Embryonic; includes blastocystic.  Cells obtained from inner cell mass of a blastocyst.  Pluripotent- Flexible, give rise to any cell type in the body. Early stem cells
  • 7.
  • 8.  who did it first?  - In 1998, U. Wisconsin research team isolates stem cells from IVF- blastocysts.
  • 9.
  • 10.  Early stem cells are pluripotent.  Retain the special ability to develop into nearly any cell type.  Teratoma
  • 11.  1998- James Thomson`s lab isolates the first human embryonic stem cells.  1999- First successful human transplant of insulin making cells from cadavers.  2000- president Bill Clinton allowed funding of reasearch on cells derived from aborted human fetuses, but not from embryonic cells.  2001- President bush restricts federal funding for embryonic stem cell research.  2004- ballot measures for $3 billion bond for stem cells.
  • 12.  STEM CELL therapy is the use of stem cell to treat or prevent a disease or condition. Bone marrow transplant is a form of stem cell therapy that has been used for many years because it has proven to be effective in clinical trails.  Stem cell implantation may help in strengthening the left ventricle of the heart, as well as retaining the heart tissues to patients who have suffered from heart attacks in the past.
  • 13.  Stem cell treatment may lower the symptoms of the disease or condition that is being treated.  The lowering of symptoms may allow patients to reduce the drug intake of the disease or condition.  Stem cell treatment may also provide knowledge for society to further stem cell understanding and future treatments.  Ome may prevent the danger of surgical interventions using stem cell.
  • 14.  STEM CELL treatment may require immunosuppression because of a requirement for radiation before the transplant to remove the person`s previous cells.  Stem cell could also form tumors after transplantation.  Harvesting cells from blastocyst result in death of the blastocyst.  Pluripotency in certain cells could also make it difficult to obtain the exact cell type needed.