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MANAGEMENT OF OPEN
FRACTURES
Dr Abhishek Pathak
Asso Prof
Orthopaedics
GMC Bhopal
OPEN FRACTURES
• Fracture- Discontinuity of
bone
• An open fracture is one in
which break in the skin
and underlying soft tissue
leads to communication
of fracture hematoma to
external environment.
• Open fractures are also
known as compound
fracture
ETIOLOGY
HIGH ENERGY TRAUMA
• Caused by high energy
trauma most commonly
from direct blow by road
traffic accident or fall
from hieght.
• These fractures can be
caused by high energy
twisting injuries.
CRUSH INJURY
• a force is applied to an immobilized portion of
the body.
• Causes Muscle ischaemia due to occlusion of
blood vessels by pressure
• When blood flow is restored causes
reperfusion injury – due to circulation of
myoglobin –can damage kidney, brain & lung
function
• CRUSH Syndrome
Gun Shot injury
• Effectiveness depends
on dissipation of energy
to local soft tiisue
• Most of time extent of
soft tissue damage
more than size of
wound
Blast Injury
• Supersonic shock wave
causing extensive
damage
• Higher severity score
• Shear forces ripping
muscle tendon nerves
vessels apart
Epidemiology
• Usually diaphyseal
• Tibia commonest
Etiology
• High energy trauma so
– Severe bony and soft tissue involvement
– Decreased blood supply
– Contamination
– Degloving
Open Fractures
Treatment = amputation
Mortality 75%
Function in “survivors” poor
Prognosis
• Outcome is improved
– Intensive care management
– Availablity of powerful antibiotics
– Radical debridement
– Immidiate bony stablisation
– Early soft tissue involvement
CLASSIFICATION
The classification of open fractures is most reliably done in
the operating room at the completion of primary wound
care and debridement.
Gustilo and Anderson classification
• relatively simple
• It has been validated with regard to time to
union, incidence of nonunion, and the need
for bone grafting.
major disadvantage
• not accurate
• Subjective nature of injury description
resulting in high interobserver variability
Gustilo and Anderson classification
Grade 1 < 1 cm clean wound, with a
simple fracture pattern.
Grade 2. > 1 cm wound and a low
energy fracture pattern
Grade 3 high-energy or crush injuries
with extensive muscle
damage.
Gustilo and Anderson classification
Grade 3A
.
has adequate bone coverage
by local soft tissues.
Grade 3B has soft-tissue loss over the
bone with some contamination
or periosteal stripping, which
requires a local or free tissue
transfer.
Grade 3C is an arterial injury, requiring
repair, associated with any
fracture pattern
Goals in the treatment of open fractures
• The treatment of high-energy injuries aims at
preserving life, limb, and function, in that
order of priority.
• The intermediate objectives are:
• Prevention of infection
• Fracture stabilization
• Soft-tissue coverage
• Evaluation entire patient
– injury protocols (ATLS)
• Evaluation limb
– complete evaluation (as possible)
– wound covered & limb splinted- “one look”
– antibiotics
– tetanus “prophylaxis”
ANALGESIA
• Preoperative planning
Stages of care
Initial assessment
• Important components in assessing traumatized
extremity
1. History and mechanism of injury
2. Neurovascular status
3. Size of skin wound
4. Muscle crush or loss
5. Periosteal stripping or bone loss
6. Fracture pattern, fragmentation
7. Contamination
8. Compartment syndrome
Primary surgery
Irrigation
• Supplements systemic debridement in
removing foreign material and decreasing
bacterial load.
Fracture type Vol of fluid used for irrigation
Type I 3 L
Type 2 6L
Type 3 9L
Irrigation
2 adages….
• If a little does some good, a lot will do a great
deal more
• solution to pollution is dilution
Irrigation
• NS normally used for
irrigation.
• Antibiotic solution is no
better than soap for open
fracture irrigation
• Antiseptic solutions have
been not shown to decrease
infection rates.
• Surfactant(non sterile soap)
same effectiveness, less
tissue damage n more
economical.
Timing of debridement and irrigation
• Most guidelines recommend debridement
within 6 hrs.
• Scientific evidence for 6 hour rule is lacking
and a little delay for better team coordination
improves results
• Serial debridement may be necessary every
24-48hrs until the wound viability is ensured
extent of wound & degree of contamination
injury environment
practice protocols
cephalosporin
+ aminoglycoside (or alternative gram (-) coverage for gross soft tissue damage
+ metronidazole (farm/soil/ischemia)
Antibiotics
Antibiotics
• Early administration of antibiotics is
associated with improved outcome (<3 Hrs)
• Antibiotics should be continued for atleast 24
hours after primary wound closure in type I
and II fracture and 72 hours in type III
fractures.
Tetanus prophylaxis
• Tetanus Toxoid(TT), dose is 0.5ml i.m.
regardless of age
• Immunoglobulin
• 75IU <5yrs of age
• 125IU 5-10yrs
• 250IU >10yrs
RE-prep & drape between 1, 2, 3
Stages of surgical treatment—the plan
• gross decontamination
• irrigation & debridement
• stabilization of fracture
• final inspection wound culture ??
• initial wound coverage
Operative treatment: “extend the
wound"
• zone of injury
• may need atypical incisions
• consider
– fracture treatment options
– soft tissue coverage & reconstruction options
• REMEMBER— I & D is 1st priority
Zone of injury
• Wound is merely a window through which a
wound communicates with exterior
• Zone of injury may be much larger
Systematic wound debridement
• remove debris
• remove non-viable soft tissues
• layer by layer
• tourniquet used only if major bleeding
• Experienced surgeon!
• inexperience  under-debridement
• The initial surgical management should be
performed by an experienced surgeon:
inadequate initial debridement has been
shown to contribute to poor outcomes
following open fractures.
Bone debridement
• Remove avascular, contaminated fragments
• Protect soft tissue attachments
• Retain key bone fragments ?
– articular surface
• Re-evaluate “crucial tissues” at 2nd debridement
Gravity Irrigation
Minimum six liters
Choice of fluid is probably
irrelevant
The solution to pollution is
dilution
Operative treatment: irrigation
Initial fracture stabilization
• Choice of stabilization technique depends on
many factors
– anatomic site of injury
– degree of contamination
– status of the wound and soft tissue(s)
– other associated injuries & treatment
– experience of surgeon & surgical team
– implant availability
Fracture stabilization—external fixation
Allows easy access to soft tissues but may
interfere with subsequent flap placement
Safest option in cases with severe
contamination or when there is a delay in
presentation
Fast application allows speedy vascular injury
repair
Speed of application is advantageous in
cases of poly-trauma
Goal of external fixation
• definitive fracture treatment ?
• temporary?
– until soft-tissue stabilization
– then change to another fixation method
Fracture stabilization - Intramedullary fixation
• Literature
– supports use in open shaft fractures
– IM “better” than ex fix for definitive
treatment
– timing
– reamed vs unreamed—no clear evidence
– Do NOT treat with immediate ORIF
unless you are sure of adequate debridement
and you are SURE of getting definitive
soft tissue cover with 72 hours
antibiotic bead pouch
VAC dressing
Initial wound management
• Goal: cover nerves, vessels, tendons, bone
• Avoid: dead tissues & space, wound tension
Antibiotic bead pouch
• Antibiotic-PMMA beads
• Occlusive dressing
• Useful in large wounds
– dead space control
– high local antibiotic concentration
– seal wound from external contamination
Closed system
Ongoing debridement
wound size
 tissue edema
Excellent for staged coverage
VAC Dressing
Mangled Extremity
Second stage management
• antibiotics 24–48 hrs
• repeat debridement 48–72 hrs as needed
Open fracture with arterial injury
• The factors that are important in the decision
making include:
• General condition of the patient (the presence of
shock)
• Warm ischemia time (more than 6 hours)
• Age of the patient (older than 30 years)
• Cut to crush ratio (blunt injuries have a large zone
of crush)
Open fracture with arterial injury
• Fasciotomy is usually mandatory following an
arterial repair, as reperfusion will result in
swelling and can cause a compartment
syndrome. Fasciotomy early in the procedure
is recommended as this facilitates surgical
exposure of vessels and bone.
Summary: open fractures
• Evaluation of patient and injury
• Initial debridement!
• Soft tissue management!
• Fracture stabilization
• Early soft-tissue closure/coverage
• Bone & soft tissue reconstruction PRN
• Rehabilitation
THANKS

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Management of open fractures final

  • 1. MANAGEMENT OF OPEN FRACTURES Dr Abhishek Pathak Asso Prof Orthopaedics GMC Bhopal
  • 2. OPEN FRACTURES • Fracture- Discontinuity of bone • An open fracture is one in which break in the skin and underlying soft tissue leads to communication of fracture hematoma to external environment. • Open fractures are also known as compound fracture
  • 4. HIGH ENERGY TRAUMA • Caused by high energy trauma most commonly from direct blow by road traffic accident or fall from hieght. • These fractures can be caused by high energy twisting injuries.
  • 5. CRUSH INJURY • a force is applied to an immobilized portion of the body. • Causes Muscle ischaemia due to occlusion of blood vessels by pressure • When blood flow is restored causes reperfusion injury – due to circulation of myoglobin –can damage kidney, brain & lung function • CRUSH Syndrome
  • 6. Gun Shot injury • Effectiveness depends on dissipation of energy to local soft tiisue • Most of time extent of soft tissue damage more than size of wound
  • 7. Blast Injury • Supersonic shock wave causing extensive damage • Higher severity score • Shear forces ripping muscle tendon nerves vessels apart
  • 9. Etiology • High energy trauma so – Severe bony and soft tissue involvement – Decreased blood supply – Contamination – Degloving
  • 10. Open Fractures Treatment = amputation Mortality 75% Function in “survivors” poor
  • 11. Prognosis • Outcome is improved – Intensive care management – Availablity of powerful antibiotics – Radical debridement – Immidiate bony stablisation – Early soft tissue involvement
  • 12. CLASSIFICATION The classification of open fractures is most reliably done in the operating room at the completion of primary wound care and debridement.
  • 13. Gustilo and Anderson classification • relatively simple • It has been validated with regard to time to union, incidence of nonunion, and the need for bone grafting. major disadvantage • not accurate • Subjective nature of injury description resulting in high interobserver variability
  • 14. Gustilo and Anderson classification Grade 1 < 1 cm clean wound, with a simple fracture pattern. Grade 2. > 1 cm wound and a low energy fracture pattern Grade 3 high-energy or crush injuries with extensive muscle damage.
  • 15. Gustilo and Anderson classification Grade 3A . has adequate bone coverage by local soft tissues. Grade 3B has soft-tissue loss over the bone with some contamination or periosteal stripping, which requires a local or free tissue transfer. Grade 3C is an arterial injury, requiring repair, associated with any fracture pattern
  • 16. Goals in the treatment of open fractures • The treatment of high-energy injuries aims at preserving life, limb, and function, in that order of priority. • The intermediate objectives are: • Prevention of infection • Fracture stabilization • Soft-tissue coverage
  • 17. • Evaluation entire patient – injury protocols (ATLS) • Evaluation limb – complete evaluation (as possible) – wound covered & limb splinted- “one look” – antibiotics – tetanus “prophylaxis” ANALGESIA • Preoperative planning
  • 19. Initial assessment • Important components in assessing traumatized extremity 1. History and mechanism of injury 2. Neurovascular status 3. Size of skin wound 4. Muscle crush or loss 5. Periosteal stripping or bone loss 6. Fracture pattern, fragmentation 7. Contamination 8. Compartment syndrome
  • 21.
  • 22. Irrigation • Supplements systemic debridement in removing foreign material and decreasing bacterial load. Fracture type Vol of fluid used for irrigation Type I 3 L Type 2 6L Type 3 9L
  • 23. Irrigation 2 adages…. • If a little does some good, a lot will do a great deal more • solution to pollution is dilution
  • 24. Irrigation • NS normally used for irrigation. • Antibiotic solution is no better than soap for open fracture irrigation • Antiseptic solutions have been not shown to decrease infection rates. • Surfactant(non sterile soap) same effectiveness, less tissue damage n more economical.
  • 25.
  • 26.
  • 27.
  • 28. Timing of debridement and irrigation • Most guidelines recommend debridement within 6 hrs. • Scientific evidence for 6 hour rule is lacking and a little delay for better team coordination improves results • Serial debridement may be necessary every 24-48hrs until the wound viability is ensured
  • 29.
  • 30.
  • 31. extent of wound & degree of contamination injury environment practice protocols cephalosporin + aminoglycoside (or alternative gram (-) coverage for gross soft tissue damage + metronidazole (farm/soil/ischemia) Antibiotics
  • 32. Antibiotics • Early administration of antibiotics is associated with improved outcome (<3 Hrs) • Antibiotics should be continued for atleast 24 hours after primary wound closure in type I and II fracture and 72 hours in type III fractures.
  • 33. Tetanus prophylaxis • Tetanus Toxoid(TT), dose is 0.5ml i.m. regardless of age • Immunoglobulin • 75IU <5yrs of age • 125IU 5-10yrs • 250IU >10yrs
  • 34. RE-prep & drape between 1, 2, 3 Stages of surgical treatment—the plan • gross decontamination • irrigation & debridement • stabilization of fracture • final inspection wound culture ?? • initial wound coverage
  • 35. Operative treatment: “extend the wound" • zone of injury • may need atypical incisions • consider – fracture treatment options – soft tissue coverage & reconstruction options • REMEMBER— I & D is 1st priority
  • 36. Zone of injury • Wound is merely a window through which a wound communicates with exterior • Zone of injury may be much larger
  • 37. Systematic wound debridement • remove debris • remove non-viable soft tissues • layer by layer • tourniquet used only if major bleeding • Experienced surgeon! • inexperience  under-debridement
  • 38. • The initial surgical management should be performed by an experienced surgeon: inadequate initial debridement has been shown to contribute to poor outcomes following open fractures.
  • 39. Bone debridement • Remove avascular, contaminated fragments • Protect soft tissue attachments • Retain key bone fragments ? – articular surface • Re-evaluate “crucial tissues” at 2nd debridement
  • 40. Gravity Irrigation Minimum six liters Choice of fluid is probably irrelevant The solution to pollution is dilution Operative treatment: irrigation
  • 41. Initial fracture stabilization • Choice of stabilization technique depends on many factors – anatomic site of injury – degree of contamination – status of the wound and soft tissue(s) – other associated injuries & treatment – experience of surgeon & surgical team – implant availability
  • 42. Fracture stabilization—external fixation Allows easy access to soft tissues but may interfere with subsequent flap placement Safest option in cases with severe contamination or when there is a delay in presentation Fast application allows speedy vascular injury repair Speed of application is advantageous in cases of poly-trauma
  • 43. Goal of external fixation • definitive fracture treatment ? • temporary? – until soft-tissue stabilization – then change to another fixation method
  • 44. Fracture stabilization - Intramedullary fixation • Literature – supports use in open shaft fractures – IM “better” than ex fix for definitive treatment – timing – reamed vs unreamed—no clear evidence – Do NOT treat with immediate ORIF unless you are sure of adequate debridement and you are SURE of getting definitive soft tissue cover with 72 hours
  • 45. antibiotic bead pouch VAC dressing Initial wound management • Goal: cover nerves, vessels, tendons, bone • Avoid: dead tissues & space, wound tension
  • 46. Antibiotic bead pouch • Antibiotic-PMMA beads • Occlusive dressing • Useful in large wounds – dead space control – high local antibiotic concentration – seal wound from external contamination
  • 47. Closed system Ongoing debridement wound size  tissue edema Excellent for staged coverage VAC Dressing
  • 49.
  • 50. Second stage management • antibiotics 24–48 hrs • repeat debridement 48–72 hrs as needed
  • 51. Open fracture with arterial injury • The factors that are important in the decision making include: • General condition of the patient (the presence of shock) • Warm ischemia time (more than 6 hours) • Age of the patient (older than 30 years) • Cut to crush ratio (blunt injuries have a large zone of crush)
  • 52. Open fracture with arterial injury • Fasciotomy is usually mandatory following an arterial repair, as reperfusion will result in swelling and can cause a compartment syndrome. Fasciotomy early in the procedure is recommended as this facilitates surgical exposure of vessels and bone.
  • 53. Summary: open fractures • Evaluation of patient and injury • Initial debridement! • Soft tissue management! • Fracture stabilization • Early soft-tissue closure/coverage • Bone & soft tissue reconstruction PRN • Rehabilitation