6. Types of Study Design
األبحاث وتصنيف أنوع
Study Designs
وصفية بحوث
Descriptive studies
مسحية دراسات
Surveys
Case report-
study
خاصة حالة دراسة
Case series
حاالت دراسة
تطبيقية
وتحليلية Analytical
-
المالحظة
-
وصفي
Observational
Ecological Cross-sectional
study -
مقطعية
Cohort study-
مستقبلية دراسة
Case-control- دراسة
للوراء رجعية
تجريبيه Experimental
Controlled Trials
Randomized Non-randomized
Uncontrolled
(no comparison
gp)
7. Meta-analysis and systematic
reviews of RCTs
Randomized controlled Trial
study (RCTs)
RCTs followed by
non-randomized CTs
Cohort studies
Case-control studies
Cross-sectional Studies
Ecologic Studies
Case-series / Case-reports
Sources:
Murad MH, Asi N, Alsawas M, Alahdab F. New evidence pyramid. Evid Based Med 2016; 21(4): 125-7
Kunzli et al. The Semi-individual Study in Air Pollution Epidemiology; A Valid Design as Compared to
Ecologic Studies. EHP 1997, 105 (10).
Hierarchy of Evidence
10. What editors look for in
a good manuscript ?
•Quality البحث جودة
• good science: well, planned, well executed study
• good presentation – Abstract ??
•Significance and originality البحث وتأصيل أهمية
•Consistent with scope of journal بالمجلة عالقتة
•Demonstrated broad interest to readership
•Will it cite?
•Well written ‘story’ الكتابة طريقة فن
•Author enthusiasm والبحث للفكرة المؤلف حماس
11. Attracting the editor/reader
• There are lots of opportunities for rejection!
• Remember: your paper is competing with many
others for the attention of editors and readers
• Title
– Brief, interesting, accurate and Attractive .
• Abstract
– Attract readers to your paper
– Aim for 4 sections: why, how, what and implications
– Include important keywords for searching
– Make it clear and easy to read
12. What constitutes a good journal?
Impact factor – (web of Science) العلوم شبكة ISI
average number of times published papers are cited up to two
years after publication.
( االخيرة سنتين خالل البحث بهذا األستشهادات عدد) المجلة قوة لقياس
Immediacy Index –
average number of times published papers are cited during year of
publication.
( االخيرة سنة خالل البحث بهذا األستشهادات عدد)
H-index- هيرسك مؤشر- Scopus
بينهم والمفاضلة الباحثين قوة مقياس
(
األخرين قبل من الباحث ببحوث األستشهاد مرات عدد
نفسها البيانات بقاعدة مفهرسة علمية مجالت في
.
Google Scholar ( google scholar Metrics )
13. The Editor’s Decision
• Based on the peer reviewers’ advice, the
editor’s own evaluation, the amount of space
in the journal, other factors
• Options:
– Accept as is (rare)
– Accept if suitably revised
– Reconsider if revised
– Reject ( more in good journals)
17. (Our Objectives in this presentation )
To Know and to Discuss What is the :
1. Research Ethics?
2. What are the most important Principles of
research ethics ?
3. Scientific Misconduct ( سوء
السلوك
-
السرقات )
4. Guidelines of research ethics.
5. Ethics committees in research( IRB or REC).
18.
19. Top ten “POOR” behaviors
► 1. Falsifying or ‘cooking’ research data
► 2. Ignoring major aspects of human-subject requirements
► 3. Not properly disclosing involvement in firms whose
products are based on one‘s own research
► 4. Relationships with students, research subjects or clients
that may be interpreted as questionable
► 5. Using another’s ideas without obtaining permission or
giving due credit (plagiarism)
► 6. Unauthorized use of confidential information in
connection with one’s own research
► 7. Failing to present data that contradict one’s own
previous research ????
► 8. Circumventing certain minor aspects of human-subject
requirements
20. Top ten behaviors
(continued)
► 9. Overlooking others' use of wrong or unpropertied data
or questionable
interpretation of data
► 10. Changing the design, methodology or results of a study in
response to pressure from a funding source (falsification)
► Other behaviors
► 11. Publishing the same data or results in two or more
publications
► 12. Inappropriately assigning authorship credit
► 13. Withholding details of methodology or results in papers or
proposals
► 14. Using inadequate or inappropriate research designs
► 15. Dropping observations or data points from analyses based
on a gut feeling that they were inaccurate
► 16. Inadequate record keeping related to research projects
21. Privacy vs. Confidentiality
Privacy
About people
Sense of being in
control of access
that others have to
ourselves
A Right to be
Protected
Confidentiality
Extension of privacy
About identifiable data
an Agreement about
maintenance and who
has access to
identifiable data
HIPAA - protects patients
from inappropriate
disclosures of "Protected
Health Information" (PHI)
من
العلمي البحث أخالقيات
v
المصداقية
(Truthfulness)
v
المهنية
)
Professionalism
(
v
السالمة
(Safety)
v
الثقة
(Trust)
v
الموافقة
Consent)
(
22. Definitions
Privacy –
about people and our sense of being in
control of others access to ourselves or to
information about ourselves with others.
Confidentiality –
treatment of identifiable, private
information that has been disclosed to
others.
من
العلمي البحث أخلقيات
v
المصداقية
(Truthfulness)
v
المهنية
)
Professionalism
(
v
السلمة
(Safety)
v
الثقة
(Trust)
v
الموافقة
Consent)
(
v
الدقة
)
Accuracy
(
v
المسؤولية
)
(Responsibility)
v
االمانة
العلمية
)
(Integrity)
v
التعاون
)
Collaboration
(
v
المعلومات سرية
Confidentiality
)
(
v
الموضوعية
)
Objectivity
(
أخالقيات
البحث
العلمي
23. Informed Consent
NOT just a signed document
NOT a one time event
A process of shared
decision-making
between subject
and investigator.
• Consent- is An
Autonomous
authorization of
a medical
intervention
by… individual
patients-
(Beauchamp
(2004)
24. Parties of Research Ethics
REC or IRB
Researcher
Sponsor
Community representative
26. Scientific correctness العلمية الناحية
Appropriate informed consent المتنورة الموافقة
Confidentiality protection السرية
Compliance with the protocol البحث متابعة
Respect the research integrity البحث مجموعة وتناسق عن مسؤول
Compliance with REC (IRB ) requirements البحوث بأخالقيات الخاصة اللجنة مع التواصل
Responsible for writing and publication of the Research -Post-study duties
P .I Primary investigator
Responsibilities الرئيس الباحث
27.
28. “Misconduct in Science means fabrication, falsification,
plagiarism or other practices that seriously deviate
from commonly accepted within the scientific
community for proposing, conducting, or reporting
research.”
US federal policy, 42 CFR 50.102
Definition of Scientific Misconduct (
(
السلوك سوء
-
السرقات
29. It does not include honest error or
honest differences in
interpretations or judgment of data
Definition of Scientific Misconduct
30. Scientific Misconduct – 1 -
•1- Research Fraud ( البحثي أإلحتيال )
•Fabrication – making it up
• (
التلفيق
-
أصال موجدة غير معلومات
)
• Falsification – changing the true description
التزييف
/
التزوير
-
الموجودة المعلومات تغيير
) )
• 2- Plagiarism السرقة – taking the words and ideas of
others without citation (
انتحال
وسرقة
الكلمات أو اآلراء
) that
seriously deviate from the Reality .
31. Scientific Misconduct – 2 -
•.
•3- Other Misconduct
• self plagiarism -
• add my name to Research without any participation .
• salami publication أبحاث لعدة البيانات نفس استخدام .
•change in scientific certifications .
• cheating in Exam .
•conflict of interest .
•Publishing in fake ( not real Journals )
32. DOCUMENTATION
التوثيق
-
بمصدره النص إلحاق عملية هو
القارئ إمداد و واضحة بصورة االصلي
المصدر لتتبع كافية بمعلومات
Reference المصادر قائمة
A reference is the bibliographic information
33. Survey of College Students
(200) students assignments
75 % admit to some cheating.
41 % have Plagiarized through the Internet.
The Center for Academic Integrity, 2002.
34. Types of Misconduct Total %
Fabrication 18
Falsification 64
Plagiarism 8
Fabrication/Falsification 47
Other 13
*Adapted from report of Office of Research Integrity, Scientific Misconduct Investigations
(ORI,)
Type of Misconduct in other study
in 150 Cases: of student's report
35. It is making up data or results and
recording or reporting them.
( Creation of data without proper experimentation
or changing the numbers to improve the results).
Fabrication التلفيق
-
معلومات
المعلومات موجودة غير
36. Misconduct – Examples:
Fabrication:
• Creating records/ Filling up missing data.
• Making up progress reports
• Creating records of calls and follow-up
(ORI web-site of Office of Research Integrity, )
37. Manipulating research materials,
equipment, or processes, or changing or
omitting data or results such that the
research is not accurately represented in
the research record.
Falsification -
التزييف
/
التزوير
-
تغيير
المعلومات
38. Fraud or Falsification
Fraud means: االنتحال أو التزييف
Turning in someone else's writing as your
own;
Inventing statistics or sources that do not
exist;
Falsifying evidence.
العلمي السطو تهمة في الوقوع
39. Misconduct – Examples:
Falsifications:
Subject substitution one for another.
False reporting of data.
Altering results of subject’s eligibility visit.
Altering dates on screening.
Failing to update subject’s record when it is
required.
Altering tests on blood samples.
Falsifying the times that blood samples were
drawn from human subjects.
42. “the appropriation of another person’s
ideas, processes, results, or words
without giving appropriate credit.”
Plagiarism الكلمات أو اآلراء انتحال
43. Plagiarism
Plagiarism
Is the presentation of words, ideas, images, or
creative works without
giving proper credit to their originators.
It is an academic crime—even when
plagiarism is unintentional.
العلمي للسطو مبسط تعريف
44. Misconduct – Examples:
Plagiarism:
Copycat (verbatim) of large portions of
another publication without attribution.
Rephrasing of an original idea as one’s own
original idea without attribution.
Lack of acknowledgement of previous work.
- نفسه الشخص عمل من السرقة
- ( self plagiarism).
45. Duplication of publication
Repeat publication or
publication of the same work
in a different journal or forum.
Occasionally, an article may be a
chapter in another book or
symposium.
46. • Money
• Reputation
• Fame (International recognition/Nobel Prize .
• Conflict of Interest
• Promotion
• Pressure to produce
• Poor Training
• Complex research environment/competition
Factors Contributing and
supporting Scientific Misconduct
52. Who Can Be Cited For
Misconduct
Primary Investigator
(He-She is responsible for all study activities)
Sub Investigators
Research Staff
53. Plagiarism Detection Tools
During the 20 years that OSI/ORI have existed,
investigators have developed a number of computer-
assisted tools and approaches to help strengthen
institutional findings. As
grammerly programmer
Research by ORI (office of Research Integrity)
54. Many FREE Plagiarism Detection Tools
Anti-Plagiarism
Anti-Plagiarism is a software designed to effectively detect and thereby prevent
plagiarism.
DupliChecker
PaperRater
Paper Rater offers three tools: Grammar Checking, Plagiarism Detection and Writing
Suggestions.
Plagiarisma.net
PlagiarismChecker
PlagiarismChecker.com makes it simple for educators to check whether a student's
paper has been copied from the Internet.
Plagium
PlagTracker
56. How to Prevent It
Training, training, and
more
والتدريب المعرفة
للجميع والتعليم
57.
58.
59. - FINAL SUMMARY
Scientific Misconduct Definition
• Fabrication – making it up
• (
التلفيق
-
أصال موجدة غير معلومات
)
• Falsification – changing the true description
التزييف
/
التزوير
-
الموجودة المعلومات تغيير
) )
• Plagiarism – taking the words and ideas of others
without citation (
انتحال
وسرقة
الكلمات أو اآلراء
)
•that seriously deviate from the Reality
•Other – self plagiarism - add may name to Research
without any participation , change in scientific
certifications , cheating in Exam )