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E B O L A 
SRIRAM MOHANAKUMAR 
GROUP:6
WHAT IS EBOLA 
• Ebola, previously known as Ebola haemorrhagic fever, is a 
rare and deadly disease caused by infection with one of the 
Ebola virus strains. 
• Ebola is caused by infection with a virus of the 
family Filoviridae , genus Ebola virus. 
• Ebola viruses are found in several African countries. Ebola 
was first discovered in 1976 near the Ebola River in what is 
now the Democratic Republic of the Congo. Since then, 
outbreaks have appeared sporadically in Africa.
EPIDEMOLOGY 
• The disease typically occurs in 
outbreaks in tropical regions of Sub- 
Saharan Africa. From 1976 (when it 
was first identified) through 2013, 
the World Health Organization 
reported 1,716 confirmed cases. 
• The largest outbreak to date is the 
ongoing 2014 West Africa Ebola virus 
outbreak, which is 
affecting Guinea, Sierra 
Leone, Liberia and Nigeria. 
• As of 25 October 2014, 10,141 
suspected cases and 4,922 deaths 
had been reported.
symptoms 
• Fever 
• Severe headache 
• Muscle pain 
• Weakness 
• Diarrhoea 
• Vomiting 
• Abdominal pain 
• Unexplained haemorrhage (bleeding or 
bruising) 
Symptoms may appear anywhere from 2 
to 21 days after exposure to Ebola, but 
the average is 8 to 10 days.
TRANSMISSION 
Ebola is spread through direct 
contact (through broken skin or 
mucous membranes in, for example, 
the eyes, nose, or mouth) with 
• blood or body fluids (including but 
not limited to urine, saliva, sweat, 
feces, vomit, breast milk, and 
semen) of a person who is sick with 
Ebola 
• objects (like needles and syringes) 
that have been contaminated with 
the virus
TRANSMISSION 
• infected fruit bats or primates 
(apes and monkeys) 
• Ebola is not spread through the 
air or by water, or in general, by 
food. However, in Africa, Ebola 
may be spread as a result of 
handling bush meat (wild 
animals hunted for food) and 
contact with infected bats. 
There is no evidence that 
mosquitos or other insects can 
transmit Ebola virus.
DIAGNOSIS 
• Diagnosing Ebola in an person who has been infected for only a few days 
is difficult, because the early symptoms, such as fever, are nonspecific to 
Ebola infection and are seen often in patients with more commonly 
occurring diseases, such as malaria and typhoid fever. 
• However, if a person has the early symptoms of Ebola and has had contact 
with the blood or body fluids of a person sick with Ebola, contact with 
objects that have been contaminated with the blood or body fluids of a 
person sick with Ebola, or contact with infected animals, they should be 
isolated and public health professionals notified. 
• Samples from the patient can then be collected and tested to confirm 
infection.
Laboratory tests used in diagnosis include:
TREATMENT 
• No FDA-approved vaccine or medicine (e.g., antiviral drug) 
is available for Ebola. 
• Symptoms of Ebola are treated as they appear. The 
following basic interventions, when used early, can 
significantly improve the chances of survival: 
• Providing intravenous fluids (IV)and balancing electrolytes 
(body salts) 
• Maintaining oxygen status and blood pressure 
• Treating other infections if they occur
TREATMENT 
• Experimental vaccines and treatments for Ebola are under 
development, but they have not yet been fully tested for safety or 
effectiveness. 
• Recovery from Ebola depends on good supportive care and the 
patient’s immune response. People who recover from Ebola infection 
develop antibodies that last for at least 10 years, possibly longer. 
• It isn't known if people who recover are immune for life or if they can 
become infected with a different species of Ebola. 
• Some people who have recovered from Ebola have developed long-term 
complications, such as joint and vision problems.
PREVENTION 
• There is no FDA-approved vaccine 
available for Ebola. 
• If you travel to or are in an area 
affected by an Ebola outbreak, 
make sure to do the following: 
• Practice careful hygiene. For 
example, wash your hands with 
soap and water or an alcohol-based 
hand sanitizer and avoid contact 
with blood and body fluids.
PREVENTION 
• Do not handle items that may have 
come in contact with an infected 
person’s blood or body fluids (such 
as clothes, bedding, needles, and 
medical equipment). 
• Avoid funeral or burial rituals that 
require handling the body of 
someone who has died from Ebola. 
• Avoid contact with bats and 
nonhuman primates or blood, 
fluids, and raw meat prepared from 
these animals.
RISK OF EXPOSURE 
• Healthcare providers caring for Ebola patients and the 
family and friends in close contact with Ebola patients are 
at the highest risk of getting sick because they may come in 
contact with the blood or body fluids of sick patients. 
• People also can become sick with Ebola after coming in 
contact with infected wildlife. For example, in Africa, Ebola 
may spread as a result of handling bushmeat (wild animals 
hunted for food) and contact with infected bats. 
• The virus also can be spread through contact with objects 
(like clothes, bedding, needles, syringes/sharps or medical 
equipment) that have been contaminated with the virus or 
with infected animals.
REFERENCES 
• http://www.cdc.gov/vhf/ebola/index.html 
• http://www.uptodate.com/contents/epid 
emiology-pathogenesis-and-clinical-manifestations- 
of-ebola-and-marburg-virus- 
disease 
• http://en.wikipedia.org/wiki/Ebola_virus_ 
disease 
• http://www.ecdc.europa.eu/en/press/ne 
ws/_layouts/forms/News_DispForm.aspx? 
List=8db7286c-fe2d-476c-9133- 
18ff4cb1b568&ID=1042 
• http://www.nhs.uk/conditions/ebola-virus/ 
pages/ebola-virus.aspx
Ebola

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Ebola

  • 1. E B O L A SRIRAM MOHANAKUMAR GROUP:6
  • 2. WHAT IS EBOLA • Ebola, previously known as Ebola haemorrhagic fever, is a rare and deadly disease caused by infection with one of the Ebola virus strains. • Ebola is caused by infection with a virus of the family Filoviridae , genus Ebola virus. • Ebola viruses are found in several African countries. Ebola was first discovered in 1976 near the Ebola River in what is now the Democratic Republic of the Congo. Since then, outbreaks have appeared sporadically in Africa.
  • 3. EPIDEMOLOGY • The disease typically occurs in outbreaks in tropical regions of Sub- Saharan Africa. From 1976 (when it was first identified) through 2013, the World Health Organization reported 1,716 confirmed cases. • The largest outbreak to date is the ongoing 2014 West Africa Ebola virus outbreak, which is affecting Guinea, Sierra Leone, Liberia and Nigeria. • As of 25 October 2014, 10,141 suspected cases and 4,922 deaths had been reported.
  • 4. symptoms • Fever • Severe headache • Muscle pain • Weakness • Diarrhoea • Vomiting • Abdominal pain • Unexplained haemorrhage (bleeding or bruising) Symptoms may appear anywhere from 2 to 21 days after exposure to Ebola, but the average is 8 to 10 days.
  • 5. TRANSMISSION Ebola is spread through direct contact (through broken skin or mucous membranes in, for example, the eyes, nose, or mouth) with • blood or body fluids (including but not limited to urine, saliva, sweat, feces, vomit, breast milk, and semen) of a person who is sick with Ebola • objects (like needles and syringes) that have been contaminated with the virus
  • 6. TRANSMISSION • infected fruit bats or primates (apes and monkeys) • Ebola is not spread through the air or by water, or in general, by food. However, in Africa, Ebola may be spread as a result of handling bush meat (wild animals hunted for food) and contact with infected bats. There is no evidence that mosquitos or other insects can transmit Ebola virus.
  • 7. DIAGNOSIS • Diagnosing Ebola in an person who has been infected for only a few days is difficult, because the early symptoms, such as fever, are nonspecific to Ebola infection and are seen often in patients with more commonly occurring diseases, such as malaria and typhoid fever. • However, if a person has the early symptoms of Ebola and has had contact with the blood or body fluids of a person sick with Ebola, contact with objects that have been contaminated with the blood or body fluids of a person sick with Ebola, or contact with infected animals, they should be isolated and public health professionals notified. • Samples from the patient can then be collected and tested to confirm infection.
  • 8. Laboratory tests used in diagnosis include:
  • 9. TREATMENT • No FDA-approved vaccine or medicine (e.g., antiviral drug) is available for Ebola. • Symptoms of Ebola are treated as they appear. The following basic interventions, when used early, can significantly improve the chances of survival: • Providing intravenous fluids (IV)and balancing electrolytes (body salts) • Maintaining oxygen status and blood pressure • Treating other infections if they occur
  • 10. TREATMENT • Experimental vaccines and treatments for Ebola are under development, but they have not yet been fully tested for safety or effectiveness. • Recovery from Ebola depends on good supportive care and the patient’s immune response. People who recover from Ebola infection develop antibodies that last for at least 10 years, possibly longer. • It isn't known if people who recover are immune for life or if they can become infected with a different species of Ebola. • Some people who have recovered from Ebola have developed long-term complications, such as joint and vision problems.
  • 11. PREVENTION • There is no FDA-approved vaccine available for Ebola. • If you travel to or are in an area affected by an Ebola outbreak, make sure to do the following: • Practice careful hygiene. For example, wash your hands with soap and water or an alcohol-based hand sanitizer and avoid contact with blood and body fluids.
  • 12. PREVENTION • Do not handle items that may have come in contact with an infected person’s blood or body fluids (such as clothes, bedding, needles, and medical equipment). • Avoid funeral or burial rituals that require handling the body of someone who has died from Ebola. • Avoid contact with bats and nonhuman primates or blood, fluids, and raw meat prepared from these animals.
  • 13. RISK OF EXPOSURE • Healthcare providers caring for Ebola patients and the family and friends in close contact with Ebola patients are at the highest risk of getting sick because they may come in contact with the blood or body fluids of sick patients. • People also can become sick with Ebola after coming in contact with infected wildlife. For example, in Africa, Ebola may spread as a result of handling bushmeat (wild animals hunted for food) and contact with infected bats. • The virus also can be spread through contact with objects (like clothes, bedding, needles, syringes/sharps or medical equipment) that have been contaminated with the virus or with infected animals.
  • 14. REFERENCES • http://www.cdc.gov/vhf/ebola/index.html • http://www.uptodate.com/contents/epid emiology-pathogenesis-and-clinical-manifestations- of-ebola-and-marburg-virus- disease • http://en.wikipedia.org/wiki/Ebola_virus_ disease • http://www.ecdc.europa.eu/en/press/ne ws/_layouts/forms/News_DispForm.aspx? List=8db7286c-fe2d-476c-9133- 18ff4cb1b568&ID=1042 • http://www.nhs.uk/conditions/ebola-virus/ pages/ebola-virus.aspx