Preterm Labor, Hyperemesis Gravidarum Pathophysiology

1. Precipitating:
 dehydration
 habitual abortion
 heavy work and long travel to work
Predisposing:
 hx of cone biopsy of the cervix
Congenital uterine or cervical abnormalities
Uterine contraction before end of Sex: female
 hx of genitourinary infections or renal disease
37th week of gestation (persistent Genetics
 hx of induced abortion, preterm delivery, or
uterine contractions 4/20mins) Age
perinatal death
with cervical effacement >80% Race (African-American)
 low socioeconomic class
 maternal under nutrition and inadequate weight
and dilation >1cm
gain during pregnancy
 multiple gestation
 inadequate prenatal care
 single parenthood
 smoking
 substance abuse
 chorioamnionitis
Bleeding Persistent dull, Feeling of Preterm Birth Vaginal Menstrual-like Inc vaginal Intestinal
low backache pelvic spotting, cramping discharge cramping
pressure/ (pink-tinged)
abdominal Primary neonatal
tightening complications:
Respiratory distress
syndrome
Intracranial bleeding
Possible
Chronic lung disease Pathophysiology of diarrhea
Infection
Visual impairment
Preterm Labor
Cerebral palsy.

2. Precipitating Factors: Morning Sickness High levels of hCG or Predisposing Factors:
Pancreatitis estrogen
Biliary tract disease Multiple pregnancies
Dec. secretion of free HCl in the Heredity
stomach Sex: Female
Dec. gastric motility Excessive vomiting Race: White
Drug toxicity
Inflammatory obstructive bowel
disease
Vitamin deficiency (B6)
Psychological factors (neurosis) Appetite disturbance
Weight loss Starvation
Emaciation Dehydration
Pathophysiology of
Hyperemesis
Gravidarum Fluid and electrolyte Fever Dec urine Dry skin
imbalance output
Ketosis Acetonuria Hypokalemia