www.ophthalclass.blogspot.com has the complete post.
In Part1 the topics discussed are the causes of anterior, intermediate, posterior and panuveitis. There is also a section on the associated features like history, demographics and examination findings that help to narrow down the differential diagnosis.
4. Non-infectious can be considered also as
immune related causes
Masquerade syndromes will be dealt with
separately
Idiopathic cause is included in all the uveitis
www.ophthalclass.blogspot.com
5. Anterior uveitis
Immune
Idiopathic Infectious
related
www.ophthalclass.blogspot.com
6. Intermediate uveitis
Immune
Idiopathic Infectious
related
www.ophthalclass.blogspot.com
7. Posterior uveitis
Immune
Idiopathic Infectious
related
www.ophthalclass.blogspot.com
8. Panuveitis
Immune
Idiopathic Infectious
related
www.ophthalclass.blogspot.com
9. Idiopathic Infectious Immune related
• Most common • Herpes simplex • HLA B27+/
seronegative
• Diagnosis only • Herpes zoster
spondylo-
after other • Tuberculosis
arthropathies
causes are ruled • Syphilis
out • Juvenile
rheumatoid
arthritis (JRA)
• Lens or IOL
related
www.ophthalclass.blogspot.com
10. Immune
Idiopathic Infectious
related
• Most • Tuberculosis • Sarcoidosis
common • Syphilis • Multiple
• Only after sclerosis
• Lyme disease
other causes
are ruled out
www.ophthalclass.blogspot.com
11. Infectious Immune related
Idiopathic
• Less common • Toxoplasmosis • Sarcoidosis
• Toxocariasis • Collagen vascular
diseases
• Herpes
• Retinochoroidop
(ARN/PORN/CMV)
athies
• Tuberculosis,
syphilis
www.ophthalclass.blogspot.com
12. Idiopathic Infectious Immune related
• After ruling out • Tuberculosis, • Sarcoidosis
other causes syphilis • Vogt – Kayanagi
• Lyme disease – Harada
syndrome
• Leptospirosis
• Sympathetic
• Infectious
ophthalmitis
endophthalmitis
• Beh et
syndrome
www.ophthalclass.blogspot.com
13. List of diseases can be very long indeed
Patient is NOT investigated for ALL the
diseases
Narrow down the differential diagnosis
before ordering the lab tests
www.ophthalclass.blogspot.com
14. Narrow down the differential diagnosis with
◦ Time course of disease
◦ Type of inflammation
◦ Characteristic pattern of the lesion
◦ Demographic data – age, sex, race, social history
◦ Associated systemic features
www.ophthalclass.blogspot.com
15. Anterior uveitis is the most common type of
uveitis
Idiopathic form is the most common cause of
anterior uveitis
Infections are more common in posterior
uveitis
Sarcoidosis, tuberculosis and syphilis can
present in any or all locations
www.ophthalclass.blogspot.com
16. Acute
Sudden onset, lasting up to 6 weeks
Chronic
Insiduous onset, lasting longer than 6 weeks
Recurrent
Repeated attacks with disease free intervals
www.ophthalclass.blogspot.com
18. Granulomatous Non-granulomatous
Onset Insiduous Acute
Keratic precipitates Large, greasy Fine
Mutton-fat, white White coloured
Macrophages and Lymphocytes and
epithelioid cells plasma cells
Iris nodules Generally absent
Koeppe (at pupillary
border)
Busacca (on iris
surface)
www.ophthalclass.blogspot.com
19. Granulomatous Non-granulomatous
Fundus Uncommon
Choroidal
nodules/granulomas
Course Chronic Maybe self limited
Posterior synechiae Broad based Fine
Causes Suggestive of few Many anterior uveitic
specific conditions diseases
More commonly Not helpful in
infectious formulating differential
diagnosis
www.ophthalclass.blogspot.com