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Organophosphate poisoning

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Kirie Kozanegawa
Kirie Kozanegawa
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ORGANOPHOSPHATE POISONING NOOR HAFIZAH BINTI HASSAN 2007287236
REFERENCES ,[object Object],[object Object]
INTRODUCTION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Distribution of Poisoning Cases by Types of Poison from 2001-2005
PHYSIOLOGY REVISITED
MECHANISM OF ACTION OF ORGANOPHOSPATE POISONING COVALENT BOND AGING
MECHANISM OF ACTION OF ORGANOPHOSPATE POISONING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CLINICAL PRESENTATION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PRINCIPLE OF MANAGEMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],LOADING DOSE: IV 0.5-2 mg over 5-10 min until atropinization achieved MAINTENANCE DOSE: (8 mg mix in 100 mL normal saline) at a rate of 0.02-0.08 mg/kg/hr ,[object Object],[object Object],[object Object]
CASE: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ASSESSMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MANAGEMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]

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Organophosphate poisoning

Editor's Notes

  1. Muscarinic can also be remembered as DUMBELS=diaphoresis/diarrhoea, urination, miosis, bronchorrhoea/bronchospasm/bradycardia, emesis, lacrimation, salivation.
  2. Atropinization=uniform improvement of all 5 observed parameters (miosis/diaphoresis/bradycardia/hypotension/poor air entry) If not improved  double atropine dose and re-assess