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Academia and Industry: Finding the Balance;

      Danish TT and spin-outs based
        on public research results
PRO landscape


                17 PROs – 13 with IP activities:
                - 8 Universities – 7 with IP
                - 5 Regional Hospitals – 4 with IP
                - 4 Gvt. Research Inst. – 2 with IP
Research commercialisation
      Key figures 2010


      328 Invention disclosures




       122 Patent applications




             103 LOAs
            11 spinouts
Direct and Indirect measures from
central administration since 2000
Direct:                                       Indirect

• IP Ownership regime                         • Increased investment in
                                              research base
• Refund of university
patenting costs                               • University management
                                              reform’
• Development of
                               Improved       • Reform of institutional
technology transfer
structures
                              exploitation    structure
                              of university
• Proof of Concept Funding         IP         • University performance
                                              contracts
• Training of technology
transfer officers                             • Individual appraisal and
                                              reward systems
• Guidelines and model IPR-
contracts                                     • Support for universty spin
                                              outs
• Annual commercialisation
survey                                        • IP training for students
Licensing and spinouts
      2000-2010
TTO staff educational profile
                                    2006-2010
   FT E s
70,0
                                                                9,5             10,3
60,0
              9,0            8,0
                                               8,4                              17,9
50,0                         10,3                               19,2
             10,9
40,0                                           15,4
              9,3            13,3
                                                                18,2            20,2
30,0
                                               13,7
20,0
             28,0            26,6
                                               16,7             19,4            20,3
10,0
 0,0
            2006         2007              2008             2009               2010

                    Lawyer          Business          Science          Other
KTO Staff 2008.                                                                                            Other
  (Proton Europe)             EU                   DK              Italy               Spain               countries
                        No. of       % of    No. of      % of     No.     % of       No. of   % of       No. of   % of
                        KTOs         KTOs    KTOs        KTOs     of      KTOs       KTOs     KTOs       KTOs     KTOs
                                                                 KTOs
0-1                       9          6.5%      5         38.5%    3           6.4%     1          1.6%     0          0.%
1-2                      25          18.1%     1         7.7%     17      36.2%        5          7.9%     2      13.3%
2-3                      14          10.1%     1         7.7%     8           17.%     4          6.3%     1          6.7%
3-4                      16          11.6%     2         15.4%    10      21.3%        3          4.8%     1          6.7%
4-5                      12          8.7%      0          0.%     3           6.4%     6          9.5%     3          20.%
5-6                       4          2.9%      0          0.%     1           2.1%     3          4.8%     0          0.%
6-8                      14          10.1%     2         15.4%    2           4.3%     8      12.7%        2      13.3%
8-10                      9          6.5%      1         7.7%     2           4.3%     5          7.9%     1          6.7%
10-15                    14          10.1%     1         7.7%     1           2.1%    12          19.%     0          0.%
15-20                     7          5.1%      0          0.%     0           0.%      6          9.5%     1          6.7%
20-30                     6          4.3%      0          0.%     0           0.%      4          6.3%     2      13.3%
> 30                      8          5.8%      0          0.%     0           0.%      6          9.5%     2      13.3%
Total number of KTOs     138         100.%    13         100.%    47      100.%       63      100.%       15      100.%
Total FTEs                    1,335.0              54.2                179.9               811.2               289.8
Average FTEs per KTOs          9.7                 4.2                  3.8                12.9                19.3
Goal & ressources of Copenhagen Spin-outs
   Overall goal:
     To increase the exploitation of research results and thereby
     increase the number of sustainable biotech companies
     through an intensified collaboration between key players

   Specific goal:
     To deliver 21 sustainable biotech spin-outs by end of 2014
     (double up the national output) [month 10: 21 projects in
     development phase]

   Budget: 5,4 Mill EUR
   [EU Regional fund (2,7 Mill EUR), Growth Forum (1,1 Mill EUR),
                 Partners (1,6 Mill EUR)]
The partner group consists of all TT
         players, from initial idea to spin-out
 Research institutions:
 University of                                           Research parks:
 Copenhagen
                                                    Copenhagen Bio Science
 Capital Region’s                                            Park (COBIS)
 hospitals                                                      Scion DTU
 Technical University of                                          Symbion
 Denmark

Branch organisations:                                         Seed Funds:
Danish Biotech                                                (Investor 2)

The Danish Association
of the Pharmaceutical                                          NOVO SEEDs
Industry (LIF)
                                                               SEED Capital



 Innovation incubators
 (Investor 1):             Mentors:
 CAT Innovation            Volunteer mentors with
 DTU Symbion Innovation    high spin-out
                           competences from the
                           Biotech industry
Phase 2
                                 Securement of IP rights

                                 Assembly of team
                                 Courses, ‘clinics’ (Accelerace)
                                 Establishment of local mini Proof of Concept program
                                 Preparation of Business Plan
Evaluation phase
                                    Commercialisation phase


    0-2 mdr                                             2-30 mdr




                                                 Mentors from
                   TTO Project

                                   Researchers
     Tech Scout




                                                                Investors
                                                   industry
                      Pilot




                        Research                                                        10


                         Parks
5 Points in Academia-Industry
 collaboration adressed by CSO
• Change of mindset among scientists
   – Introduce and support entrepreneurship culture
• Secure resources at the TTO for spin-outs
   – Hire people enough with proper qualifications, long term
     basis.
• Earlier involvement of industry via collaboration
   – Early involvement, but with a clear and transparent policy
• Setting the team and picking the roles in the Spin-out
   – competences, driving factors, expectations
• Keep the pace up and the bureaucracy down
   – Momentum is important as well as diminishing unnecessary
     administration
Thank you for listening




          www.copenhagenspin-outs.dk

Project manager
Gert Vilhelm Balling
gert.balling@adm.ku.dk

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Dr. gert vilhelm balling

  • 1. Academia and Industry: Finding the Balance; Danish TT and spin-outs based on public research results
  • 2. PRO landscape 17 PROs – 13 with IP activities: - 8 Universities – 7 with IP - 5 Regional Hospitals – 4 with IP - 4 Gvt. Research Inst. – 2 with IP
  • 3. Research commercialisation Key figures 2010 328 Invention disclosures 122 Patent applications 103 LOAs 11 spinouts
  • 4. Direct and Indirect measures from central administration since 2000 Direct: Indirect • IP Ownership regime • Increased investment in research base • Refund of university patenting costs • University management reform’ • Development of Improved • Reform of institutional technology transfer structures exploitation structure of university • Proof of Concept Funding IP • University performance contracts • Training of technology transfer officers • Individual appraisal and reward systems • Guidelines and model IPR- contracts • Support for universty spin outs • Annual commercialisation survey • IP training for students
  • 6. TTO staff educational profile 2006-2010 FT E s 70,0 9,5 10,3 60,0 9,0 8,0 8,4 17,9 50,0 10,3 19,2 10,9 40,0 15,4 9,3 13,3 18,2 20,2 30,0 13,7 20,0 28,0 26,6 16,7 19,4 20,3 10,0 0,0 2006 2007 2008 2009 2010 Lawyer Business Science Other
  • 7. KTO Staff 2008. Other (Proton Europe) EU DK Italy Spain countries No. of % of No. of % of No. % of No. of % of No. of % of KTOs KTOs KTOs KTOs of KTOs KTOs KTOs KTOs KTOs KTOs 0-1 9 6.5% 5 38.5% 3 6.4% 1 1.6% 0 0.% 1-2 25 18.1% 1 7.7% 17 36.2% 5 7.9% 2 13.3% 2-3 14 10.1% 1 7.7% 8 17.% 4 6.3% 1 6.7% 3-4 16 11.6% 2 15.4% 10 21.3% 3 4.8% 1 6.7% 4-5 12 8.7% 0 0.% 3 6.4% 6 9.5% 3 20.% 5-6 4 2.9% 0 0.% 1 2.1% 3 4.8% 0 0.% 6-8 14 10.1% 2 15.4% 2 4.3% 8 12.7% 2 13.3% 8-10 9 6.5% 1 7.7% 2 4.3% 5 7.9% 1 6.7% 10-15 14 10.1% 1 7.7% 1 2.1% 12 19.% 0 0.% 15-20 7 5.1% 0 0.% 0 0.% 6 9.5% 1 6.7% 20-30 6 4.3% 0 0.% 0 0.% 4 6.3% 2 13.3% > 30 8 5.8% 0 0.% 0 0.% 6 9.5% 2 13.3% Total number of KTOs 138 100.% 13 100.% 47 100.% 63 100.% 15 100.% Total FTEs 1,335.0 54.2 179.9 811.2 289.8 Average FTEs per KTOs 9.7 4.2 3.8 12.9 19.3
  • 8. Goal & ressources of Copenhagen Spin-outs Overall goal: To increase the exploitation of research results and thereby increase the number of sustainable biotech companies through an intensified collaboration between key players Specific goal: To deliver 21 sustainable biotech spin-outs by end of 2014 (double up the national output) [month 10: 21 projects in development phase] Budget: 5,4 Mill EUR [EU Regional fund (2,7 Mill EUR), Growth Forum (1,1 Mill EUR), Partners (1,6 Mill EUR)]
  • 9. The partner group consists of all TT players, from initial idea to spin-out Research institutions: University of Research parks: Copenhagen Copenhagen Bio Science Capital Region’s Park (COBIS) hospitals Scion DTU Technical University of Symbion Denmark Branch organisations: Seed Funds: Danish Biotech (Investor 2) The Danish Association of the Pharmaceutical NOVO SEEDs Industry (LIF) SEED Capital Innovation incubators (Investor 1): Mentors: CAT Innovation Volunteer mentors with DTU Symbion Innovation high spin-out competences from the Biotech industry
  • 10. Phase 2 Securement of IP rights Assembly of team Courses, ‘clinics’ (Accelerace) Establishment of local mini Proof of Concept program Preparation of Business Plan Evaluation phase Commercialisation phase 0-2 mdr 2-30 mdr Mentors from TTO Project Researchers Tech Scout Investors industry Pilot Research 10 Parks
  • 11. 5 Points in Academia-Industry collaboration adressed by CSO • Change of mindset among scientists – Introduce and support entrepreneurship culture • Secure resources at the TTO for spin-outs – Hire people enough with proper qualifications, long term basis. • Earlier involvement of industry via collaboration – Early involvement, but with a clear and transparent policy • Setting the team and picking the roles in the Spin-out – competences, driving factors, expectations • Keep the pace up and the bureaucracy down – Momentum is important as well as diminishing unnecessary administration
  • 12. Thank you for listening www.copenhagenspin-outs.dk Project manager Gert Vilhelm Balling gert.balling@adm.ku.dk