Das Institut für Integrative und Experimentelle Genomik der Universität zu Lübeck stellt sich vor.

7.  Todesursache Nummer 1 in der westlichen Welt
 200.000 Herzinfarkttote in Deutschland/Jahr

11. ´

14. 


19. 




22. •
•
•
•
•
•

25. Two
risk
variants

26. Two
normal
variants
Two
risk
variants

29. 3 – 6M + 3 – 6 M + 6-8 M + 3-4 M + 12 M + 6-8 M + 10-14 M + 6-12 M
Gene
Symbol
KO Vector KO ESC Chimera Founder Backcross
to B6
Intercross GMC Backcross to
Apoe /Ldlr
Phenotyping
Atherosc /
Neointima
Cxcl12 --- --- --- --- --- lethal
Gucy1A3 --- --- --- --- --- Done in progress in progress
Mras --- --- --- --- Done Done in progress Done in progress
Adamts7 --- Done Done --- Done in progress in progress in progress
Cyp17a1 --- Done Done --- Done in progress in progress
Ppap2b --- Done Done --- lethal
Zc3hc1 --- Done Done --- Done in progress in progress in progress
Phactr1 Done Done in progress

46. 

