Das Institut für Integrative und Experimentelle Genomik stellt sich vor.

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Das Institut für Integrative und Experimentelle Genomik der Universität zu Lübeck stellt sich vor.

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Das Institut für Integrative und Experimentelle Genomik stellt sich vor.

  1. 1.  Todesursache Nummer 1 in der westlichen Welt  200.000 Herzinfarkttote in Deutschland/Jahr
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  5. 5. • • • • • •
  6. 6. Two risk variants
  7. 7. Two normal variants Two risk variants
  8. 8. 3 – 6M + 3 – 6 M + 6-8 M + 3-4 M + 12 M + 6-8 M + 10-14 M + 6-12 M Gene Symbol KO Vector KO ESC Chimera Founder Backcross to B6 Intercross GMC Backcross to Apoe /Ldlr Phenotyping Atherosc / Neointima Cxcl12 --- --- --- --- --- lethal Gucy1A3 --- --- --- --- --- Done in progress in progress Mras --- --- --- --- Done Done in progress Done in progress Adamts7 --- Done Done --- Done in progress in progress in progress Cyp17a1 --- Done Done --- Done in progress in progress Ppap2b --- Done Done --- lethal Zc3hc1 --- Done Done --- Done in progress in progress in progress Phactr1 Done Done in progress
  9. 9.   

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