Dr. Trenton Smith, from the department of Economics at Otago University recently inaugurated the first in the 2014/15 AFRD seminar series with the talk: 'Does Financial Insecurity Make People Obese?'
1. Biology of Fattening
NLSY & ESI studies
Concluding Remarks
Does Financial Insecurity Make People Obese?
Trenton G. Smith
University of Otago, New Zealand
Department of Economics
15 October 2014
Newcastle University
Trent Smith Obesity & Economic Insecurity 1 / 35
2. Biology of Fattening
NLSY & ESI studies
Concluding Remarks
Introduction: Obesity and Material Constraints
Economic analysis of obesity typically emphasises:
price (of calories, of fat, of physical exercise...) and
income eects (poverty, wealth), perhaps conditioned on
information (nutrition education, food labels, marketing...).
One dimension typically left out is the role of stochastic
nature of economic environments.
I've argued that the extent to which income or
material well-being is uncertain or at risk may well be
more important than conventional explanations.
Motivation is from behavioural biology:
body fat as hedge against food shortage.
Good news: clear theoretical predictions;
opens door to sources of empirical evidence
previously ignored in economics
Bad news: higher moments dicult to measure;
endogeneity (still) a hurdle
Trent Smith Obesity Economic Insecurity 2 / 35
3. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Leptin
Seasonality
Sociality Serotonin
Which of these two mice is starving?
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4. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Leptin
Seasonality
Sociality Serotonin
Endocrinology of Obesity: Leptin
It has long been known that the obese-type mouse carries a recessive
gene that causes it, under free-feeding conditions, to gain weight rapidly
from birth while exhibiting the clinical symptoms of starvation:
hyperphagia
decreased body temperature
lethargy
diminished immune function
infertility
Since 1994 we've known that the ob/ob mouse lacks the gene that codes for
leptin, a peptide hormone secreted by fat cells.
In normal mice, leptin circulates in the bloodstream in proportion to
the amount of body fat, sending a signal to the brain about availability
of energy stores.
Trent Smith Obesity Economic Insecurity 4 / 35
5. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Leptin
Seasonality
Sociality Serotonin
Endocrinology of Obesity: Leptin, Cont'd
The human homologue of the normal gene
for leptin (Ob) and for the leptin receptor
were quickly identi
6. ed.
The mutant (ob) allele is exceedingly rare
but has been medically documented.
Parents of these children say that from
birth they were ...constantly hungry,
demanding food continuously and eating
considerably more than their siblings.
Initial optimism about leptin-based weight
loss drugs has not panned out.
Intriguing implications:
ob eects suggest adaptive (evolutionary)
function for body fat
subjective beliefs encoded in our genes?
Trent Smith Obesity Economic Insecurity 5 / 35
7. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Leptin
Seasonality
Sociality Serotonin
Seasonal Fattening: Siberian Hamsters
Many foraging animals
(e.g., the Siberian hamster)
fatten seasonally.
The key environmental trigger
appears to be photoperiod.
In humans, seasonal aective disorder
characterized by depression,
hypersomnia, hyperphagia, and
weight gain.
Most commonly prescribed treatment:
exposure to arti
8. cial light.
Conversely, summer depression in
humans causes insomnia,
decreased appetite, and weight loss.
Trent Smith Obesity Economic Insecurity 6 / 35
9. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Leptin
Seasonality
Sociality Serotonin
Social Rank and Obesity: Willow Tits
In natural settings, willow tits fall into
stable binary dominance hierarchies that
determine access to food supply.
In spite of restricted access to food
supply, subordinate tits typically fatter
than their dominant counterparts.
Theoretical explanation: fattening is
an optimal response to increased risk
of starvation.
Interesting corollary: if food becomes
scarce enough, direction of the
gradient reverses.
Similar pattern observed in humans?
Trent Smith Obesity Economic Insecurity 7 / 35
10. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Leptin
Seasonality
Sociality Serotonin
SSRIs
The molecular basis for the link between
(indicators of) starvation risk and body weight
are not well understood.
There is suggestive evidence however that the
serotinergic system in the brain is involved.
Serotonin injected directly into (pigeon) brain
suppresses appetite.
SSRIs, widely used as antidepressants, can cause
weight loss (and are sometimes even marketed
as weight loss drugs).
SSRIs (selective serotonin reuptake inhibitors) are
thought to work by increasing levels of serotonin
(5-HT) at neural synapses in the brain.
Trent Smith Obesity Economic Insecurity 8 / 35
11. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Leptin
Seasonality
Sociality Serotonin
Ecstasy as a Weight Loss Drug?
3,4-methylenedioxymethamphetamine
(MDMA or ecstasy) developed by Merck
in 1912 as a weight loss drug
Acts via nicotinic receptor and serotonergic
system
MDMA induces weight loss via hyperthermia,
loss of appetite, peripheral hyperactivity
Never marketed because of adverse side eects:
Feelings of euphoria and empathy, extreme
comfort, belonging, and closeness to others,
which can result in inappropriate and/or
unintended emotional bonding.
Speci
12. city of these eects suggests psychological
state conducive to weight loss?
Trent Smith Obesity Economic Insecurity 9 / 35
13. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Leptin
Seasonality
Sociality Serotonin
Tobacco
Nicotine from tobacco is known to activate
nicotinic receptors in the brain, which in turn
activate the serotinergic system.
Tobacco causes weight loss
(or prevents weight gain).
Smoking associated with unemployment,
14. nancial problems, reduced social contacts, lack
of social support, and antidepressant use
(indeed antidepressants are sometimes marketed
as aids to smoking cessation).
Coincidence of psychological correlates of
economic security with weight loss (via tobacco)
suggestive of a link between the two.
Trent Smith Obesity Economic Insecurity 10 / 35
15. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Leptin
Seasonality
Sociality Serotonin
The Insecurity Hypothesis
Given apparent adaptive function of body fat, and
many parallels between animal and human fattening,
a natural question arises:
Might variation in material risk drive incidence of obesity in
the modern world?
Trent Smith Obesity Economic Insecurity 11 / 35
17. cation in NLSY
The Economic Security Index
Two Sources of Data
A Weighty Problem
The identi
18. cation problem in obesity research is dicult.
individual choices (food, exercise, career choice...) aect BMI
unobserved heterogeneity always a concern
identi
19. cation strategy needed for causal inference
ex: Smith et al. 2009 (FHEP) used local job market conditions
to isolate eect of economic insecurity on body weight
Moreover, economic insecurity is dicult to measure.
(In 2009 study we relied on detailed employment histories to
estimate income-loss risk...leaving us with cross-section only).
Without an appropriate measure of economic insecurity, it is
not possible to address the big question of its role in the
overall trend in obesity.
A new measure has recently become available for the US:
the Economic Security Index (ESI).
Trent Smith Obesity Economic Insecurity 12 / 35
21. cation in NLSY
The Economic Security Index
Two Sources of Data
The Economic Security Index
ESI developed by researchers at Yale's
Institution for Social and Policy Studies.
Uses US Current Population Survey (CPS),
household incomes linked year-to-year by residence.
ESI is de
22. ned as the probability of 25% drop in annual
household income. (Adjusted for household size,
out-of-pocket medical expenses, household debt service,
buering eect of wealth, but excluding retirement events).
ESI is available by gender, race/ethnicity, age, household
structure, geographic (state) location, and year (currently
back to 1986).
Trent Smith Obesity Economic Insecurity 13 / 35
24. cation in NLSY
The Economic Security Index
Two Sources of Data
Empirical Strategy
Our strategy: focus on exogenous demographic
characteristics: age, gender, race/ethnicity.
Obesity data come from US National Health and Nutrition
Examination Surveys (NHANES), which provide nationally
representative repeated cross-sections with measured
height and weight for the civilian population.
NHANES surveys cover 2-3 year periods:
1990 NHANES III (phase 1), 1988{1991
1993 NHANES III (phase 2), 1992{1994
1999 NHANES 1999{2000
2001 NHANES 2001{2002
2003 NHANES 2003{2004
2005 NHANES 2005{2006
2007 NHANES 2007{2008
2009 NHANES 2009{2010
2011 NHANES 2011{2012
Trent Smith Obesity Economic Insecurity 14 / 35
26. cation in NLSY
The Economic Security Index
Two Sources of Data
50
40
30
20
Percent Obese
US Obesity Rates, 18+
1990 1993 1996 1999 2002 2005 2008
year
White NH Men
Black NH Men
Hispanic Men
White NH Women
Black NH Women
Hispanic Women
Source: NHANES
NHANES
Trent Smith Obesity Economic Insecurity 15 / 35
30. cation in NLSY
The Economic Security Index
Two Sources of Data
80
70
60
50
40
30
20
10
0
80
70
60
50
40
30
20
10
0
80
70
60
50
40
30
20
10
0
Age 20-24 Age 25-29 Age 30-34 Age 35-39
Age 40-44 Age 45-49 Age 50-54 Age 55-59
Age 60-64 Age 65-69 Age 70-74 Age 75+
.1 .15 .2 .25 .3 .35 .1 .15 .2 .25 .3 .35 .1 .15 .2 .25 .3 .35 .1 .15 .2 .25 .3 .35
White NH Men Black NH Men Hispanic Men
White NH Women Black NH Women Hispanic Women
Percent Obese
Economic Security Index (ESI)
Trent Smith Obesity Economic Insecurity 17 / 35
34. + ij
where
BMIij is individual i 's obesity status (body mass index 30),
ESIj is individual i 's economic security index, as determined
by year and exogenous demographic characteristics,
Xij is a vector of i 's personal characteristics and exogenous
demographic indicators (possibly including year of survey), and
ij is a disturbance term.
Linear probability model.
Hypothesis of interest: HA : 0
Trent Smith Obesity Economic Insecurity 18 / 35
46. cation in NLSY
The Economic Security Index
Two Sources of Data
Table 4C: Eect of Economic Insecurity on Child BMI z-scores
(1) (2) (3) (4) (5)
ESI 0.631***
ESI*1990 0.593
ESI*1993 1.435**
ESI*1999 0.748*
ESI*2001 -0.118
ESI*2003 0.891
ESI*2005 1.086**
ESI*2007 -0.0730
ESI*2009 -0.0507
ESI*Male 0.174
ESI*Female 1.150***
ESI*Black NH -0.331*
ESI*White NH 2.138***
ESI*Hispanic 0.108
ESI*Other NH 0.770***
ESI*Age 0-4 -0.355
ESI*Age 5-9 0.218
ESI*Age 10-14 1.319**
ESI*Age 15-19 0.997***
Trent Smith Obesity Economic Insecurity 24 / 35
47. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
Whitehall Study Stumbles upon a Natural Experiment
Michael Marmot's Whitehall Study has followed more than 10,000
British civil servants for many years, conducting periodic interviews
and medical exams to better understand the interaction of
socioeconomic and employment experience with health outcomes.
In the early 1990s one of the 19 departments covered by Whitehall
(the Property Services Administration) was privatised.
Because privatisation threatened the job security of PSA employees,
Marmot's group had the opportunity to study the eects of the
threat of insecurity, and then the eects of actual privatisation.
Two eects in particular were noted (any guesses?).
1 An increase in body weight (0.5 kg for men, 1 kg for women).
2 An increase in the odds of sleeping 9 hours per night.
Q: When do you suppose these eects were observed?
(A: On the rumour. The uncertainty, not the change itself,
seems to have triggered the response).
Trent Smith Obesity Economic Insecurity 25 / 35
48. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
% Obese
35
30
25
20
15
10
0 Year
1980 1985 1990 1995 2000 2005
5
Australia
Austria
Canada
Czech Republic
Denmark
England
Finland
France
Iceland
Italy
Japan
Netherlands
New Zealand
Spain
Sweden
Switzerland
United States
Trent Smith Obesity Economic Insecurity 26 / 35
49. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
Economic Policy and Household-Level Risk
Why has the obesity epidemic been more severe in some countries
(US, Iceland, New Zealand, Australia, England, Spain...)
than in others (France, Switzerland, Austria, Japan...)?
Public policy can aect the extent to which households are
subject to
50. nancial risks. In particular, over the past 35 years
many countries have pursued neoliberal economic policies,
characterized by:
expanded international trade
privatisation of state-owned assets
oating exchange rate
monetary policy emphasising price stability
rather than full employment
weakening of social safety net
elimination of labour protections
diminished antitrust enforcement
Could obesity epidemic be an unintended side eect?
Trent Smith Obesity Economic Insecurity 27 / 35
51. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
Australia
Finland
United States
Iceland
Netherlands
Japan
Spain
France
Denmark
New Zealand
Sweden
England
Austria
Switzerland
Italy
Canada
Annual
Growth
in
Obesity
(%)
0 5 10 15 20 25
Revenue from Sales of State-Owned Enterprises (% of 1985 GDP)
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1
Privatization and Obesity in the OECD, 1985-1999
Trent Smith Obesity Economic Insecurity 28 / 35
52. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
Trent Smith Obesity Economic Insecurity 29 / 35
53. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
Trent Smith Obesity Economic Insecurity 30 / 35
54. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
Trent Smith Obesity Economic Insecurity 31 / 35
55. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
America's Great Risk Shift
ESI suggests economic insecurity has risen in the U.S. since
the 1980s. Why?
Some likely culprits:
1974-present Health insurance subscriptions down (Hacker 2006)
1979-present Rising income instability
(Gottschalk and Mott 2009)
1980-present Creative destruction
stemming from decline in antitrust enforcement
(Lynn 2010)
1981-present Pensions: from pooled to individual risk
1994-present NAFTA and outsourcing
1996-present Welfare reform
1999-present Financial deregulation
Trent Smith Obesity Economic Insecurity 32 / 35
56. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
Obesity and Welfare Regimes
Trent Smith Obesity Economic Insecurity 33 / 35
57. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
Summary Re
ections
Obesity and Insecurity
The insecurity hypothesis is broadly consistent with the
incidence of obesity in human populations.
Open questions: particular cues? proximate mechanisms?
Larger issue: does economic liberalisation
(or, more generally, do economic incentives) always imply a
trade-o between eciency insecurity?
(...with opportunity to succeed comes threat of failure...)
Trent Smith Obesity Economic Insecurity 34 / 35
58. Biology of Fattening
NLSY ESI studies
Concluding Remarks
Insecurity and Economic Policy
Conclusion
Worries go down better with soup than without.
{Jewish proverb
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