What are the roots of the childhood obesity epidemic? <ul><li>“ Our genes load the gun but our environment pulls the trigg...
All disease epidemics  are … <ul><li>Genetic environmental interactions  </li></ul><ul><li>Exponential in growth unless li...
Mean Body Mass Index of Parents of Four Weight Classes of Adoptees     Stunkard, A., Sorensen, T. Hanis C. Teasdale T., Ch...
“ Genetic influences on BMI and abdominal adiposity are high in children born since the onset of the pediatric obesity epi...
BMI and prevalence of diabetes among Pima Indians Living in  Maycoba, Mexico and Arizona    Pratley R. Gene-environment in...
What does a genetic- environmental action look like? It reminds me of something… G x E = X  ²
Here we go… Percentage of U.S. Children and Adolescents who were overweight 1963-2002   National Center for Health Statist...
What are the causes of obesity besides our genes?   Diet (refined carbohydrates and too many calories) Physical Inactivity...
Intra-uterine programming?!?!? <ul><li>This would be epigenetics: the science of how our genes and environment interact. <...
What this mean?   <ul><li>Obesity is an evolutionary response to chemicals and/or a high caloric/low nutrient diet.    </l...
What we need to do?   <ul><li>Change our habits, diversify our food supply with nutrient rich foods: high in folates, Omeg...
Remember Jamie Oliver’s Food Revolution? <ul><li>What makes the Huntington, West Virginia area so unique?  </li></ul><ul><...
What happens if we do nothing?   Where we are now. 20 15 10 5 % 10 15 20 25 30 35 40 45 50 NHANES  1976-1980 NHANES 2005 -...
If trends continue … 20 15 10 5 % 10 15 20 25 30 35 40 45 50 NHANES  1976-1980 NHANES 2005 -2006 The FUTURE!!! BMI
This can’t happen!   20 15 10 5 % 10 15 20 25 30 35 40 45 50 The FUTURE!!! BMI
I can’t imagine living such a world but let me guess… <ul><li>Diabetes rate 33% or more  </li></ul><ul><li>Fertility rate ...
Since our conventional armed forces will be limited by the epidemic… our only logical option will be…   See: Too Fat to Fi...
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What Are The Roots Of The Childhood Obesity Epidemic

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What Are The Roots Of The Childhood Obesity Epidemic

  1. 1. What are the roots of the childhood obesity epidemic? <ul><li>“ Our genes load the gun but our environment pulls the trigger.” – George Bray </li></ul>
  2. 2. All disease epidemics are … <ul><li>Genetic environmental interactions </li></ul><ul><li>Exponential in growth unless limited by </li></ul><ul><li>death, immunity and/or infertility </li></ul><ul><li>Have a J or S curve </li></ul>
  3. 3. Mean Body Mass Index of Parents of Four Weight Classes of Adoptees Stunkard, A., Sorensen, T. Hanis C. Teasdale T., Chakraborty R., Schull W., Schulsinger F., Adoption Study of Human Obesity, NEJM v. 314 January 23 ,1986 No.4 pp.193-197
  4. 4. “ Genetic influences on BMI and abdominal adiposity are high in children born since the onset of the pediatric obesity epidemic.” … “Targeting the family may be vital for obesity prevention in the earliest years but longer term weight control will require a combination of individual engagement and society wide efforts to modify the environment especially for children at high genetic risk.” Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment -- Wardle et al. 87 (2): 398 – American Journal of Clinical Nutrition
  5. 5. BMI and prevalence of diabetes among Pima Indians Living in Maycoba, Mexico and Arizona Pratley R. Gene-environment interactions in pathogenesis of Type 2 Diabetes Mellitus: lessons learned from the Pima Indians Proceeding of the Nutrition Society 1998, 57, 175 -181
  6. 6. What does a genetic- environmental action look like? It reminds me of something… G x E = X ²
  7. 7. Here we go… Percentage of U.S. Children and Adolescents who were overweight 1963-2002 National Center for Health Statistics
  8. 8. What are the causes of obesity besides our genes? Diet (refined carbohydrates and too many calories) Physical Inactivity Stress Lack of sleep Air conditioning Pollution…Chemicals like- BpA , DDE, PCBs, TCDD and TBT. Neophobia - the fear of new foods Food deserts Safe neighborhoods Screen time on computer and TV Advertising Viral Infections Quit Smoking Aging Intra-uterine programming?!?!? http://slimeasydiet.com/what-causes-obesity / Factors like stress, diet and pollution can lead to a maternal intra-uterine gene programming creating a transgenerational response in your offspring
  9. 9. Intra-uterine programming?!?!? <ul><li>This would be epigenetics: the science of how our genes and environment interact. </li></ul>YouTube - NOVA | Ghost in Your Genes YouTube - The Ghost In Your Genes - Part 1 YouTube - The Ghost In Your Genes - Part 3 YouTube - The Ghost In Your Genes - Part 2 YouTube – BBC Horizon The Ghost in your Genes Part 4 YouTube -BBC Horizon The Ghost in your Genes - Part 5 -
  10. 10. What this mean? <ul><li>Obesity is an evolutionary response to chemicals and/or a high caloric/low nutrient diet. </li></ul>
  11. 11. What we need to do? <ul><li>Change our habits, diversify our food supply with nutrient rich foods: high in folates, Omega 3s and fiber. </li></ul><ul><li>Promote the limitation of refined low nutrient / high calorie foods </li></ul><ul><li>Ban trans fats </li></ul><ul><li>Cut subsidies of unhealthy commodities (like corn, rice and sugar) </li></ul><ul><li>Promote physical activity </li></ul><ul><li>Limit television advertising to kids </li></ul>
  12. 12. Remember Jamie Oliver’s Food Revolution? <ul><li>What makes the Huntington, West Virginia area so unique? </li></ul><ul><li>The answer can found in the movie: “We are Marshall.” </li></ul><ul><li>The loss of the football team in the plane crash amplified the effect of stress and obesity across generations. No one in the community was left unaffected. </li></ul>
  13. 13. What happens if we do nothing? Where we are now. 20 15 10 5 % 10 15 20 25 30 35 40 45 50 NHANES 1976-1980 NHANES 2005 -2006 This chart shows the distribution of BMI between 1976-1980 and 2005-2006 BMI
  14. 14. If trends continue … 20 15 10 5 % 10 15 20 25 30 35 40 45 50 NHANES 1976-1980 NHANES 2005 -2006 The FUTURE!!! BMI
  15. 15. This can’t happen! 20 15 10 5 % 10 15 20 25 30 35 40 45 50 The FUTURE!!! BMI
  16. 16. I can’t imagine living such a world but let me guess… <ul><li>Diabetes rate 33% or more </li></ul><ul><li>Fertility rate falls </li></ul><ul><li>Morality rate rises </li></ul><ul><li>Civil unrest / health care crisis </li></ul><ul><li>Global systemic economic collapse </li></ul><ul><li>Famine </li></ul><ul><li>Large scale natural selection </li></ul><ul><li>And lastly… </li></ul>
  17. 17. Since our conventional armed forces will be limited by the epidemic… our only logical option will be… See: Too Fat to Fight

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