11. valproic acid during pregnancy for
migraine was category "D" (the
potential benefit of the drug in
pregnant women may be acceptable
despite its potential risks)
12. ⢠use will be changed to "X" (the risk of use
in pregnant women clearly outweighs any
possible benefit of the drug).
⢠Valproate products will remain in
pregnancy category D for treating epilepsy
and manic episodes associated with bipolar
disorder
⢠[posted 6-5-2013]
14. Critically examined
Should meet the following criteria:
1. More than one source should be
used when appropriate.
2. The extent of agreement between
sources should be determined if sources
donât agree , good judgment should be
used.
15. Relevant data
Must be presented in a manner that
applies directly to the circumstances
under consideration (e.g., patient
parameters, therapeutic objectives,
alternative approaches
23. Primary sources
Primary sources are original materials
on which research is based
o represent original thinking
o report on Discoveries
o share new information
24. Primary sources
They are usually the first formal
appearance of results
⢠neither interpreted
⢠nor condensed
⢠nor evaluated by other writers.
28. Secondary sources
⢠are those which review,
compare, contrast, repackage,
reorganize, interpret,
summarize, index or
otherwise âadd valueâ to the
new
31. Tertiary Sources
⢠is a specific subject area, or
materials in which the information
from secondary sources has been
"digested"
⢠reformatted and condensed, to put it
into a convenient, easy-to-read form.
42. WHY DIC?
1-Lack of awareness of the
principles of rational drug use
among healthcare
professionals.
43. WHY DIC?
2-There are more than 20,000
biomedical journals available and
more than 6,000 articles published
everyday. It is not possible for a
person to have access to all the
information
44. WHY DIC?
3-Lack of adequate drug information
due to
ďź limited availability
ďźlack of current literature
ďź poor documentation
ďźpoor funding available.
51. Objectives
4.To provide accurate and unbiased
medicines information service to the
healthcare professionals
4.To provide accurate and unbiased
medicines information service to the
healthcare professionals
4.To provide accurate and unbiased
medicines information service to the
healthcare professionals