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Chem 166 (185) Research Project (Week 9): Synthesis of a Phenothiazine Derivative SbCls
SbCls DCM, 0 °C, 10 min F3C CF3 F3C
Solution
SbCl5 - Antimony pentachloride
Potential Acute Health Effects: Extremely hazardous in case of skin contact (corrosive,
irritant), of eye contact (irritant), of ingestion, of inhalation. Liquid or spray mist may produce
tissue damage particularly on mucous membranes of eyes, mouth and respiratory tract. Skin
contact may produce burns. Inhalation of the spray mist may produce severe irritation of
respiratory tract, characterized by coughing, choking, or shortness of breath. Inflammation of the
eye is characterized by redness, watering, and itching. Skin inflammation is characterized by
itching, scaling, reddening, or, occasionally, blistering.
Potential Chronic Health Effects : Extremely hazardous in case of skin contact (corrosive,
irritant), of eye contact (irritant), of ingestion, of inhalation.
The substance is toxic to lungs, mucous membranes. Repeated or prolonged exposure to the
substance can produce target organs damage. Repeated or prolonged contact with spray mist may
produce chronic eye irritation and severe skin irritation. Repeated or prolonged exposure to spray
mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.
Repeated or prolonged inhalation of vapors may lead to chronic respiratory irritation.

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Chem 166 (185) Research Project (Week 9)- Synthesis of a Phenothiazine.docx

  • 1. Chem 166 (185) Research Project (Week 9): Synthesis of a Phenothiazine Derivative SbCls SbCls DCM, 0 °C, 10 min F3C CF3 F3C Solution SbCl5 - Antimony pentachloride Potential Acute Health Effects: Extremely hazardous in case of skin contact (corrosive, irritant), of eye contact (irritant), of ingestion, of inhalation. Liquid or spray mist may produce tissue damage particularly on mucous membranes of eyes, mouth and respiratory tract. Skin contact may produce burns. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Potential Chronic Health Effects : Extremely hazardous in case of skin contact (corrosive, irritant), of eye contact (irritant), of ingestion, of inhalation. The substance is toxic to lungs, mucous membranes. Repeated or prolonged exposure to the substance can produce target organs damage. Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection. Repeated or prolonged inhalation of vapors may lead to chronic respiratory irritation.