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MYOCARDIAL PROTECTION IN REDO
SURGERY WITH PATENT LEFT
INTERNAL MAMMARY ARTERY
By
Dr . Vijayanand palanisamy,
Dr . Anbarasu mohanraj
• A very high percentage of patients submitted to coronary
artery bypass grafting (CABG) develop symptomatic aortic
disease requiring surgery upon ageing.
• The widespread use of the LIMA and its high patency rate
have made it quite common to reoperate in the presence of
well-functioning coronary bypass grafts.
CASE REPORT
• CASE 1
Mr.Kathiresan 64 year old gentleman
k/c/o s/p cabg * 4 grafts (2002), Native LM with TVD ,Patent
LIMA ->LAD graft , occluded SVG->RAMUS , SVG ->Distal RCA ,
SVG->OM2 , Severe calcific AS , Mild AR , Mild MR , moderate
PAH , Moderately severe LVD (EF – 35%)
- Patient underwent REDO CABG * 2 GRAFTS (SVG->RAMUS ,
SVG ->PDA) + AVR using 19mm On-X VALVE
Operative details
Median sternotomy
Adhesions released and lima pedicle partial dissection done
carefully
CPB establised through aortic and DSSV cannulation
AXC and transverse aortotomy
Cold antegrade blood cardioplegia given through ostia
intermittently
Moderate hypothermia and systemic hyperkalemia
maintained
LIMA flow left undisturbed
LA vented
Native aortic valve excised and calcium removed carefully
Distal anastomosis done
While replacing aortic valve , due to excess return from Left
main coronary ostia , LIMA is clamped using soft bulldog for a
short interval
AVR done . LIMA clamp released . Aortotomy closed and
proximal anastomosis of vein grafts done onto aorta .
Came off CPB
CPB time : 141 min
AXC : 89 min
• CASE 2
Mr . Subramanian .M 63 year old gentleman k/c/o CCF , CAD
– native TVD , S/p CABG * 3 grafts LIMA -> LAD , SVG -> OM ,
SVG -> RCA-PDA (2011) , Severe calcific AS , Grade II AR , Mild
MR ,Severe LVD EF -33%
-Patient underwent AVR using 21 mm On-X valve
Operative details
Median sternotomy
Adhesions released and lima is not dissected
CPB establised through femoro-femoral bypass
AXC and oblique aortotomy
Cold antegrade blood cardioplegia given through coronary
ostia and venous graft ostia intermittently
Moderate hypothermia and systemic hyperkalemia
maintained
LA vented
Native aortic valve excised and calcium removed carefully
Aortic valve replaced and Aortotomy closed
Came off CPB
CPB time – 62min
AXC time – 30 min
REVIEW OF LITERATURE
Gillinov et al ;
• The traditional approach has been median sternotomy
followed by meticulous dissection and clamping of the IMA ,
however this procedure does carry a small but significant risk
of 5-6 % damage to the artery which can be disastrous
especially in the setting of calcified and poor quality native
coronary arteries
Gonçalo S. Paupério et al;
• Valve surgery was performed with non-dissection of the
internal thoracic artery graft, when patent, and antegrade
cardioplegic arrest of other territories
• Concomitant CABG was always performed prior to AVS, in an
empty beating or fibrillating heart, a technique described in
detail in a previous report by this group, which had also been
used in the original operation (1)
• If collateral backflow out of the left main ostium (from the
patent LITA) obscured the operative field during AVS, pump
flows were temporarily turned down for better visualization,
or the ostium was occluded by placing a cardioplegia cannula.
Savitt et al ;
• An alternative approach that avoids myocardial reperfusion
injury resulting from cardioplegic arrest is to perform beating
heart AVR with continued use of CPB, antegrade and/or
retrograde perfusion, and LIMA unclamped. In a series of 16
patients using this method, Savitt and colleagues reported a
mortality rate of 0%.
• One of the methods described has been cannulating the
coronary ostia and perfusing with oxygenated blood and
aortic valve replacement is done on a beating heart perfusing
any venous grafts if present intermittently.
Byrne et al ; and Lytle et al ;
- open IMA technique with deep hypothermia (20°C ) and aortic
cross
- -useful in minimally invasive surgery where IMA dissection can
be dangerous and time consuming.
Ravishankar Venkataraman et al ;
• alternative methods to avoid dissection of IMA and carry out
AVR by establishing deep hypothermia using axillary artery
cannulation, keeping a hyperkalaemic state and using
retrograde/antegrade cardioplegia for myocardial protection
Theodore Velissaris et al;
• The technique consists of preoperative insertion of a suitably sized
angioplasty balloon catheter into the proximal part of the graft
under fluoroscopic guidance. Intraoperative inflation of the balloon
results in occlusion of the graft during aortic cross-clamping .
1. Antunes PE, Oliveira JF, Antunes MJ. Non-cardioplegic coronary surgery in patients with severe left
ventricular dysfunction. Eur J Cardiothorac Surg 1999;16:331–6.
2. Lytle BW, McElroy D, McCarthy P, Loop FD, Taylor PC, et al. Influence of arterial coronary bypass grafts
on the mortality in coronary reoperation. J Thorac Cardiovasc Surg 1994; 107: 675–83.
3. Akins CW, Hilgenberg AD, Vlahakes GJ, Madsen JC,
MacGillivray TE. Aortic valve replacement in patients
with previous cardiac surgery. J Card Surg 2004; 19:
308–12.
4. Byrne JG, Karavas AN, Filsoufi F, Mihaljevic T,
Aklog L, et al. Aortic valve surgery after previous coronary artery bypass grafting with functioning
internal
mammary artery grafts. Ann Thorac Surg 2002; 73:
779–84.
5. Savitt MA, Singh T, Agrawal S, Choudhary A, Chaugle
H, et al. A simple technique for aortic valve replacement
in patients with a patent left internal mammary artery
bypass graft. Ann Thorac Surg 2002; 74: 1269–70.
6. Gillinov AM, Casselman FP, Lytle BW et al. Injury to a patent left internal thoracic artery graft at
coronary reoperation. Ann Thorac Surg 1999; 67: 382–86
7. Ravishankar Venkataraman et al . Aortic valve surgery in patients with patent internal mammary graft .
Ind J Thorac Cardiovasc Surg, 2007; 23: 211-214
8. Bar-El Y, Kophit A, Cohen O, Kertzman V. Continuous retrograde cardioplegia simplifies aortic valve
replacement in the presence of a patent internal mammary artery. Ann Thorac Surg 2003;76(4):1337-8
9. Gonçalo S. Paupério et al . Aortic valve surgery in patients who had undergone surgical myocardial
revascularization previously . European Journal of Cardio-Thoracic Surgery 42 (2012) 826–831
10. Theodore Velissaris et al , Myocardial Protection during Reoperative Cardiac Surgery Tex Heart Inst J
2010;37(1):75-8
Thank U

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MYOCARDIAL PROTECTION IN REDO SURGERY WITH PATENT LIMA

  • 1. MYOCARDIAL PROTECTION IN REDO SURGERY WITH PATENT LEFT INTERNAL MAMMARY ARTERY By Dr . Vijayanand palanisamy, Dr . Anbarasu mohanraj
  • 2. • A very high percentage of patients submitted to coronary artery bypass grafting (CABG) develop symptomatic aortic disease requiring surgery upon ageing. • The widespread use of the LIMA and its high patency rate have made it quite common to reoperate in the presence of well-functioning coronary bypass grafts.
  • 3. CASE REPORT • CASE 1 Mr.Kathiresan 64 year old gentleman k/c/o s/p cabg * 4 grafts (2002), Native LM with TVD ,Patent LIMA ->LAD graft , occluded SVG->RAMUS , SVG ->Distal RCA , SVG->OM2 , Severe calcific AS , Mild AR , Mild MR , moderate PAH , Moderately severe LVD (EF – 35%) - Patient underwent REDO CABG * 2 GRAFTS (SVG->RAMUS , SVG ->PDA) + AVR using 19mm On-X VALVE
  • 4. Operative details Median sternotomy Adhesions released and lima pedicle partial dissection done carefully CPB establised through aortic and DSSV cannulation AXC and transverse aortotomy Cold antegrade blood cardioplegia given through ostia intermittently Moderate hypothermia and systemic hyperkalemia maintained
  • 5. LIMA flow left undisturbed LA vented Native aortic valve excised and calcium removed carefully Distal anastomosis done While replacing aortic valve , due to excess return from Left main coronary ostia , LIMA is clamped using soft bulldog for a short interval AVR done . LIMA clamp released . Aortotomy closed and proximal anastomosis of vein grafts done onto aorta . Came off CPB CPB time : 141 min AXC : 89 min
  • 6.
  • 7. • CASE 2 Mr . Subramanian .M 63 year old gentleman k/c/o CCF , CAD – native TVD , S/p CABG * 3 grafts LIMA -> LAD , SVG -> OM , SVG -> RCA-PDA (2011) , Severe calcific AS , Grade II AR , Mild MR ,Severe LVD EF -33% -Patient underwent AVR using 21 mm On-X valve
  • 8.
  • 9. Operative details Median sternotomy Adhesions released and lima is not dissected CPB establised through femoro-femoral bypass AXC and oblique aortotomy Cold antegrade blood cardioplegia given through coronary ostia and venous graft ostia intermittently Moderate hypothermia and systemic hyperkalemia maintained
  • 10. LA vented Native aortic valve excised and calcium removed carefully Aortic valve replaced and Aortotomy closed Came off CPB CPB time – 62min AXC time – 30 min
  • 12. Gillinov et al ; • The traditional approach has been median sternotomy followed by meticulous dissection and clamping of the IMA , however this procedure does carry a small but significant risk of 5-6 % damage to the artery which can be disastrous especially in the setting of calcified and poor quality native coronary arteries
  • 13. Gonçalo S. Paupério et al; • Valve surgery was performed with non-dissection of the internal thoracic artery graft, when patent, and antegrade cardioplegic arrest of other territories • Concomitant CABG was always performed prior to AVS, in an empty beating or fibrillating heart, a technique described in detail in a previous report by this group, which had also been used in the original operation (1) • If collateral backflow out of the left main ostium (from the patent LITA) obscured the operative field during AVS, pump flows were temporarily turned down for better visualization, or the ostium was occluded by placing a cardioplegia cannula.
  • 14. Savitt et al ; • An alternative approach that avoids myocardial reperfusion injury resulting from cardioplegic arrest is to perform beating heart AVR with continued use of CPB, antegrade and/or retrograde perfusion, and LIMA unclamped. In a series of 16 patients using this method, Savitt and colleagues reported a mortality rate of 0%. • One of the methods described has been cannulating the coronary ostia and perfusing with oxygenated blood and aortic valve replacement is done on a beating heart perfusing any venous grafts if present intermittently.
  • 15. Byrne et al ; and Lytle et al ; - open IMA technique with deep hypothermia (20°C ) and aortic cross - -useful in minimally invasive surgery where IMA dissection can be dangerous and time consuming.
  • 16. Ravishankar Venkataraman et al ; • alternative methods to avoid dissection of IMA and carry out AVR by establishing deep hypothermia using axillary artery cannulation, keeping a hyperkalaemic state and using retrograde/antegrade cardioplegia for myocardial protection
  • 17. Theodore Velissaris et al; • The technique consists of preoperative insertion of a suitably sized angioplasty balloon catheter into the proximal part of the graft under fluoroscopic guidance. Intraoperative inflation of the balloon results in occlusion of the graft during aortic cross-clamping .
  • 18. 1. Antunes PE, Oliveira JF, Antunes MJ. Non-cardioplegic coronary surgery in patients with severe left ventricular dysfunction. Eur J Cardiothorac Surg 1999;16:331–6. 2. Lytle BW, McElroy D, McCarthy P, Loop FD, Taylor PC, et al. Influence of arterial coronary bypass grafts on the mortality in coronary reoperation. J Thorac Cardiovasc Surg 1994; 107: 675–83. 3. Akins CW, Hilgenberg AD, Vlahakes GJ, Madsen JC, MacGillivray TE. Aortic valve replacement in patients with previous cardiac surgery. J Card Surg 2004; 19: 308–12. 4. Byrne JG, Karavas AN, Filsoufi F, Mihaljevic T, Aklog L, et al. Aortic valve surgery after previous coronary artery bypass grafting with functioning internal mammary artery grafts. Ann Thorac Surg 2002; 73: 779–84. 5. Savitt MA, Singh T, Agrawal S, Choudhary A, Chaugle H, et al. A simple technique for aortic valve replacement in patients with a patent left internal mammary artery bypass graft. Ann Thorac Surg 2002; 74: 1269–70. 6. Gillinov AM, Casselman FP, Lytle BW et al. Injury to a patent left internal thoracic artery graft at coronary reoperation. Ann Thorac Surg 1999; 67: 382–86 7. Ravishankar Venkataraman et al . Aortic valve surgery in patients with patent internal mammary graft . Ind J Thorac Cardiovasc Surg, 2007; 23: 211-214 8. Bar-El Y, Kophit A, Cohen O, Kertzman V. Continuous retrograde cardioplegia simplifies aortic valve replacement in the presence of a patent internal mammary artery. Ann Thorac Surg 2003;76(4):1337-8 9. Gonçalo S. Paupério et al . Aortic valve surgery in patients who had undergone surgical myocardial revascularization previously . European Journal of Cardio-Thoracic Surgery 42 (2012) 826–831 10. Theodore Velissaris et al , Myocardial Protection during Reoperative Cardiac Surgery Tex Heart Inst J 2010;37(1):75-8