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Courtesy Dr. Julie Gralow
1
LO 1 Define neuroscience and explain its contributions to our
understanding of behavior.
LO 2 Label the parts of a neuron and describe an action
potential.
LO 3 Illustrate how neurons communicate with each other.
LO 4 Summarize various neurotransmitters and the roles they
play in human behavior.
LO 5 Recognize the connections between the central and
peripheral nervous systems.
Courtesy Dr. Julie Gralow
LO 6 Evaluate pseudopsychology and its relationship to critical
thinking.
LO 7 Describe how psychologists use the scientific method.
LO 8 Summarize the importance of a random sample.
LO 9 Recognize the forms of descriptive research.
LO 10 Explain how the experimental method relates to cause
and effect.
LO 11 Demonstrate an understanding of research ethics.
Courtesy Dr. Julie Gralow
LO 12 Compare and contrast tools scientists use to study the
brain.
LO 13 Identify the lobes of the cortex and explain their
functions.
LO 14 Recognize the association areas and identify their
functions.
LO 15 Distinguish the structures and functions of the limbic
system.
LO 16 Distinguish the structures and functions of the brainstem
and cerebellum.
Courtesy Dr. Julie Gralow
Biology and Behavior:
Studying the Last Frontier
Neuroscience
Involves study of the brain and nervous system
Biological psychology
Focuses on how the brain and other biological systems influence
human behavior
Contributions
Examination of extent of experience-induced neural plasticity
Courtesy Dr. Julie Gralow
5
Biology and Behavior:
Studying the Last Frontier
Brandon Burns poses for a photo at the Marine Corps Recruit
Depot in Parris Island, South Carolina in the fall of 2003. The
following year, he was shot in the head by an enemy sniper in
the Battle of Fallujah.
Doctors concluded that some parts of his brain were no longer
viable. “They removed part of my skull and dug out the injured
part of my brain,” and now, Brandon says, “one third of my
brain is gone.”
What were the consequences of his injury?
Brandon Burns in the military
Courtesy Dr. Julie Gralow
Neuroscience
Contributions
Biological psychology
6
Courtesy Dr. Julie Gralow
The neuron, the basic building block of the nervous system, has
three main components: (1) the cell body, which contains vital
cellular structures; (2) bushy dendrites that receive messages
from neighboring neurons; and (3) a long, thin axon that sends
messages to other neurons through its branchlike terminal buds.
James Cavallini/Photo Researchers, Inc.
7
Can you identify the structure of a typical neuron?
Courtesy Dr. Julie Gralow
Cell body: Region of the neuron that a nucleus containing DNA,
protein-producing mechanisms, and other structures that nourish
the celi
Dendrites: Tiny, branchlike fibers extending from the cell body
that receive messages from other neurons and send information
in the direction of the cell body
Axon: Skinny tubelike structure of a neuron that extends from
the cell body, and which sends messages to other neurons.
Myeline sheath: Fatty substance that insulates the axon and
speeds the transmission of neural messages.
Synapse: Tiny gap between a terminal bud of one axon and a
neighboring dendrite of the next neuron junction between
neurons where communication occurs.
8
Cell body
Dendrites
Axon
Terminal buds
Myelin sheath
Synapse
Biology and Behavior
Glia to the Rescue
A scanning electron micrograph shows neurons (green) and glia
(orange).
Glial cells serve as the “glue” of the nervous system, providing
cohesion and support for the neurons. Thomas Deerinck,
NCMIR
Some classes of glial cells
Microglia
Astrocytes
Schwann
Thomas Deerinck, NCMIR / Science Source
Courtesy Dr. Julie Gralow
COMMUNICATION WITHIN NEURONS
THE NEURON AT REST
2. THE ACTION POTENTIAL
3. ACTION POTENTIAL TRAVELS LENGTH OF AXON
Courtesy Dr. Julie Gralow
Communication within neurons
Neural communication involves different processes within and
between neurons. In this infographic, we follow the electrical
action that conveys messages within the neuron, from one end
to the other.
1. THE NEURON AT REST
Before communication begins, the neuron is “at rest.” Closed
channels in the cell membrane prevent some positive ions from
entering the cell, and the inside of the cell is slightly more
negative than the charge outside. At –70 mV, the cell is at its
resting potential.
2. THE ACTION POTENTIAL
This graph shows the characteristic electrical trace of the action
potential. When the neuron is stimulated, positive ions enter the
cell, making the axon less negative (A). When the charge
reaches threshold (–55 mV), an action potential is triggered.
Positive ions flood the cell, quickly reversing the charge from
negative to positive (B). Afterward, the cell is restored to
resting potential (C).
ACTION POTENTIAL TRAVELS LENGTH OF AXON
The action potential occurring in one axon segment causes a
voltage change in the next, initiating an entirely new action
potential there. This sequential action travels along the axon
like a wave, carrying the message from axon hillock to terminal
buds.
10
Biology and Behavior:
Studying the Last Frontier
COMMUNICATION WITHIN AND BETWEEN
Resting potential
Electrical potential of cell at rest
Solution
s on either side of the membrane wall come into equilibrium;
slightly more negative charge inside
Courtesy Dr. Julie Gralow
Biology and Behavior:
Studying the Last Frontier
COMMUNICATION WITHIN AND BETWEEN
Action potential
Involves spike in electrical energy that passes through the axon
of a neuron, the purpose of which is to convey information
Is all-or-none
Every time a segment of the axon fires
Positive sodium ions flood in from the outside of the cell, while
the prior segment returns to its resting potential, all along the
length of the axon to its end
Courtesy Dr. Julie Gralow
Biology and Behavior:
Studying the Last Frontier
COMMUNICATION WITHIN AND BETWEEN
Excitatory signals
Occur when enough combine, sending neurons signal the
receiving neuron to pass along message
Inhibitory signals
Inhibit neuron from releasing a signal through the axon
Courtesy Dr. Julie Gralow
Biology and Behavior:
COMMUNICATION WITHIN AND BETWEEN
Myelin sheath insulates and protects the tiny spikes in
electricity happening inside the axon.
Action potential “skips” over the segments of myelin, hopping
from one node to the next, instead of traversing the entire
length of the axon.
MYELIN
Protein that envelops and insulates the axon, facilitating faster
transmission of the impulse.
Jean-Claude Revy, ISM/Phototake
Courtesy Dr. Julie Gralow
Biology and Behavior:
Studying the Last Frontier
COMMUNICATION BETWEEN
Neurotransmitters
Chemical messengers that neurons use to communicate at the
synapse
Receptor sites
Location where neurotransmitters attach on the receiving side of
the synaptic gap
Reuptake
Process by which neurotransmitters are reabsorbed by the
sending terminal bud
Courtesy Dr. Julie Gralow
Biology and Behavior
Axon terminal of a sending neuron interacts with the dendrites
of a receiving neuron by releasing chemical messengers
(neurotransmitters) into the synapse.
Once the neurotransmitters migrate across the gap and latch
onto the dendrite’s receptor sites, the message has been
conveyed.
The Synapse
Carol and Mike Werner/Science Source
Courtesy Dr. Julie Gralow
Biology and Behavior:
Studying the Last Frontier
COMMUNICATION WITHIN AND BETWEEN
Reuptake
Occurs when neurotransmitters are reabsorbed by the sending
bud
Diffusion
Occurs when neurotransmitters are not reabsorbed and drift out
of the synaptic gap
Courtesy Dr. Julie Gralow
Courtesy Dr. Julie Gralow
Biology and Behavior:
Studying the Last Frontier
NEUOTRANSMITTERS
Acetylcholine
Relays messages from motor neurons to muscles, enabling
movement; involved in memory
Too much = spasms; too little = paralysis
Glutamate
Makes neurons fire; central role in memory and learning
Too much = strokes; too little = symptoms of schizophrenia
GABA
Inhibits neurotransmitter firing; contributes to motor control,
vision
Courtesy Dr. Julie Gralow
Biology and Behavior:
Studying the Last Frontier
NEUOTRANSMITTERS
Norepinephrine
Has variety of effects in CNS; helps body prepare for stress
Serotonin
Plays key role in controlling appetite, aggression, and mood;
regulates sleep and breathing
Dopamine
Plays role in modulating mood; plays central role in positive
reinforcement and dependency
Courtesy Dr. Julie Gralow
Biology and Behavior:
Studying the Last Frontier
NEUOTRANSMITTERS
Endorphins
Regulates secretion of other neurotransmitter; naturally
produced opioids; reduces pain and elevates mood
Agonists
Interfere at level of synapse; increase normal neurotransmitter
activity
Antagonists
Interfere at level of synapse; decrease normal neurotransmitter
activity
Courtesy Dr. Julie Gralow
Biology and Behavior
NEUOTRANSMITTERS
Caffeine
Blocks receptors for adenosine
Increases activity in branch of nervous system serving the body
istockphoto/thinkstock
Courtesy Dr. Julie Gralow
1. Many axons are surrounded by a ______ , which is a fatty
substance that insulates the axon.
2. When Brandon was injured, played an important role in his
recovery by defending against infection and inflammation of the
brain, as well as holding neurons together and maintaining the
structure of the nervous system.
a. glial cells
b. dendrites
c. action potentials
d. sodium ions
Courtesy Dr. Julie Gralow
23
3. ________are released into the ________when an action
potential reaches the branches of the terminal buds.
Sodium ions; synaptic gap
Neurotransmitters; synaptic gap
Potassium ions; cell membrane
Neurotransmitters; sodium gates
4. Neural communication is very complicated. Draw a diagram
depicting the process of neural communication, then explain it
to yourself while looking at what you have drawn.
Courtesy Dr. Julie Gralow
24
The Supporting Systems
INFRASTRUCTURE
Brain needs supporting infrastructure to carry out directives and
relay essential information from outside
Central nervous system (CNS)
Peripheral nervous system (PNS)
Courtesy Dr. Julie Gralow
Central nervous system (CNS): A major component of the
human nervous system that includes the brain and spinal cord.
Peripheral nervous system (PNS): The part of the nervous
system that connects the central nervous system to the rest of
the body.
25
THE SUPPORTING SYSTEMS
Overview of the
Nervous System
The nervous system is made up of the central nervous system,
which includes the brain and spinal cord, and the peripheral
nervous system.
moodboard/Alamy
moodboard / Alamy
Courtesy Dr. Julie Gralow
26
The Supporting Systems
Spinal cord
Includes bundle of neurons
Allows communication between the brain and the peripheral
nervous system
Connects with the body’s muscles, glands, and organs
Courtesy Dr. Julie Gralow
The Supporting Systems
Courtesy Dr. Julie Gralow
CONNECTIONS BETWEEN CNS AND PNS
28
Sensory neurons
Receive information about the environment from the sensory
systems and convey this to the brain for processing
Motor neurons
Carry information from CNS to produce movement; provide
mechanism regulated by spinal cord and brain
Interneurons
Resides in brain and spinal cord; act as bridges connecting
sensory and motor neurons
Without any input from the brain, the spinal cord neurons are
capable of creating some simple reflexive behavior.
While the spinal reflex occurs, sensory neurons also send
messages to the brain, letting it know what has happened.
THE SPINAL CORD AND REFLEX ARC
Courtesy Dr. Julie Gralow
Reflex arc: An automatic response to a sensory stimulus, such
as the “knee jerk” reaction; a simple pathway of communication
from sensory neurons through interneurons in the spinal cord
back out through motor neurons.
29
Try This
Test your knowledge of the reflex arc using Brandon as an
example. As you recall, Brandon’s brain injury led to paralysis
on the right side of his body.
What do you think would happen if a doctor tapped on his right
knee—would he experience a reflex?
Courtesy Dr. Julie Gralow
What Lies Beyond:
The Peripheral Nervous System
Peripheral nervous system
Includes all neurons not in CNS
Involves neurons that are bundled together to carry signals
throughout body
Nerves
Act as primary communication system for PNS
Supply CNS with information about body’s environment
Courtesy Dr. Julie Gralow
What Lies Beyond:
The Peripheral Nervous System
SOMATIC NERVOUS SYSTEM
Characteristics
Involves branch of the parasympathetic nervous system
Includes sensory nerves and motor nerves
Gathers information from sensory receptors
Controls the skeletal muscles responsible for voluntary
movement
Courtesy Dr. Julie Gralow
What Lies Beyond:
The Peripheral Nervous System
AUTONOMIC NERVOUS SYSTEM
Characteristics
Regulates involuntary activity
Has two divisions involved in physiological responses to stress
or crisis situations
Sympathetic nervous system
Parasympathetic nervous system
Courtesy Dr. Julie Gralow
Sympathetic nervous system: The division of the autonomic
nervous system that mobilizes the "fight-or-flight” response to
stressful or crisis situations.
Parasympathetic nervous system: The division of the autonomic
nervous system that orchestrates the "rest-anddigest”response to
bring the body back to a noncrisis mode.
33
THE SYMPATHETIC AND PARASYMPATHETIC NERVOUS
SYSTEM
PhotoObjects.net/Thinkstock
Courtesy Dr. Julie Gralow
The autonomic nervous system has two divisions, the
sympathetic and parasympathetic nervous systems.
In a stressful situation, the sympathetic nervous system initiates
the “fight-orflight” response.
The parasympathetic nervous system calms the body when the
stressful situation has passed.
PhotoObjects.net/Thinkstock
34
What Lies Beyond:
The Peripheral Nervous System
TEND AND BEFRIEND
Female response to stress
Many women have inclination to direct energy toward nurturing
and forging social bonds as a stress response
Courtesy Dr. Julie Gralow
Think Again
MALE BRAIN, FEMALE BRAIN
Studies suggest gender stereotypes can influence performance in
math and science.
Research also shows that male and female brains are far more
alike than they are different, but...
Certain regions of the limbic cortex and the frontal lobes were
larger in women
Areas of the parietal cortex, the amygdala, and hypothalamus
were larger in men
So is nature or nurture responsible for gender imbalance in math
and the science?
Courtesy Dr. Julie Gralow
Research shows that male and female brains are far more alike
than they are different, but some anatomical and functional
differences exist.
36
The Endocrine System and Its
Slowpoke Messengers
ENDOCRINE SYSTEM
Hormones
Pituitary gland
Thyroid gland
Adrenal glands
Can you define each of these?
Courtesy Dr. Julie Gralow
Endocrine system: Communication system that uses glands,
rather than neurons to convey messages.
Hormones: Chemical messengers released into the bloodstream
that influence mood, cognition, appetite, and many other
processes and behaviors.
Pituitary gland: The pea-sized gland located in the center of the
brain just under the hypothalamus; secretes hormones that
dictate the release of hormones by other glands; known as the
master gland.
Thyroid gland: Gland of the endocrine system that regulates the
rate of metabolism by secreting thyroxin.
Adrenal glands: Part of the endocrine system involved in
responses to stress as well as the regulation of salt balance.
37
The Endocrine System
left: (face) Hemera/Thinkstock, (body) Yuri Arcurs; right: Asias
elects/Getty Images
Courtesy Dr. Julie Gralow
This system of glands communicates within the body by
secreting hormones directly into the bloodstream. left: (face)
Hemera/Thinkstock, (body) Yuri Arcurs; right:
Asiaselects/Getty Images
38
The Endocrine System and Its
Slowpoke Messengers
OTHER ENDOCRINE GLANDS AND ORGANS
Pineal gland
Secretes melatonin
Pancreas
Secretes insulin
Ovaries and testes
Secrete sex hormones
Courtesy Dr. Julie Gralow
1. ________ carry information from the central nervous system
to activate various parts of the body, such as muscles and
glands.
a. Interneurons
b. Dendrites
c. Sensory neuron
d. Motor neurons
Courtesy Dr. Julie Gralow
40
2. When a stimulus causes an involuntary response, we refer to
it as a reflex arc; the simple communication pathway goes from
a sensory neuron through interneurons in the and back out
through motor neurons.
a. brain
b. spinal cord
c. axon hillock
d. nodes of Ranvier
Courtesy Dr. Julie Gralow
41
3. The ________ gland, located in the center of the brain, just
under the hypothalamus, is in charge of the endocrine system.
4. When confronted with a potentially threatening situation, the
sympathetic nervous system sometimes prepares for “fight or
flight” and/or “tend and befriend.” How would you explain
these two very different responses using the evolutionary
perspective?
Courtesy Dr. Julie Gralow
42
The Hemispheres
RIGHT BRAIN, LEFT BRAIN: THE TWO HEMISPHERES
Cerebrum
Includes largest, most highly developed part of brain
Involved in intelligence, personality, thinking, perceiving,
planning and organization, language, sensation, motor functions
Divided into right and left hemispheres and covered by corpus
callosum
Courtesy Dr. Julie Gralow
Two Hemispheres
The cerebrum looks like a walnut with its two wrinkled halves.
Regions of the left and right hemispheres specialize in different
activities, but the two sides of the brain are constantly
communicating and collaborating.
Science Source/Photo Researchers, Inc. Colorization by: Eric
Cohen
The right hemisphere controls the left side of the body, and the
left hemisphere controls the right.
This explains why Brandon, who was shot on the left side of his
head, suffered paralysis and loss of sensation on the right half
of his body.
Science Source/Photo Researchers, Inc. Colorization by: Eric
Cohe
Courtesy Dr. Julie Gralow
The Hemispheres
HEMISPHERECTOMY
Christina Santhouse relaxes with her mother at Johns Hopkins,
where she had a dramatic brain surgery known as a
hemispherectomy.
Prior to the operation, Christina experienced over 100 seizures a
day.
William Johnson
Courtesy Dr. Julie Gralow
The Hemispheres
SPLIT BRAIN
Hemispherectomies
Exceptionally rare; last resort
Callostomies (Split-brain operations)
Right and left hemisphere disconnected
Both hemispheres
Intact
After
hemispherectomy
MRI SCAN
Medical Body Scans / Science Source
Courtesy Dr. Julie Gralow
The Split-Brain Experiment
The image to the right shows a top view of the corpus callosum,
the bundle of neurons linking the right and left hemispheres.
When the corpus callosum s severed, we can easily see
functional differences between the two sides of the brain.
Studies of people who have undergone this procedure are is
shown here.
Terence H. Williams, Nedzad Gluhbegovic/Wolters Kluwer
1
3
2
Courtesy Dr. Julie Gralow
Information presented to right visual field is processed in left
hemisphere where language processing occurs. Subject can
speak the answer.
2. Information presented to left visual field is processed in right
hemisphere. Subject can’t use language to say what he was
shown.
3. The subject can touch the correct object even if he can’t say
what has been projected in his left visual field. The subject uses
his left hand, which is controlled by the right hemisphere,
where the visual information has been processed.
47
The Hemispheres
LATERALIZATION
Generalization
Left hemisphere plays a crucial role in language processing and
right hemisphere plays a crucial role in managing visual spatial
tasks
But
Hemispheres constantly integrate and share information
Courtesy Dr. Julie Gralow
The Hemispheres
LANGUAGE AND THE LEFT
Handedness and dominance
Left hemisphere controls language in most people; do not
necessarily correspond to handedness
Language dominance
Broca’s area
Wernicke’s area
Speak Again
Brandon works on his pronunciation in front of a mirror during
a speech therapy session at the Memphis VA hospital. You can
see the extent of his injury on the left side of his head. Upon
awaking from his coma, Brandon could not articulate a single
word. Today, he can hold his own in complex conversations.
A.J. Wolfe The Commercial Appeal
Courtesy Dr. Julie Gralow
The Hemispheres
LANGUAGE AREA AND THE BRAIN
Broca’s area
Wernicke’s area
Can you identify the role each structure plays in language
production and comprehension?
Wernicke’s area
Broca’s area
Courtesy Dr. Julie Gralow
Broca’s area: An area of the cortex that is critical for speech
production.
Wernicke’s area: A region of the cortex that plays a pivotal role
in language comprehension.
50
The Hemispheres
THE ROLE OF THE RIGHT
Research: Right hemisphere
More proficient in some visual tasks
Critical for understanding abstract and humorous use of
language
Better for following conversations that change topics
Important for recognizing faces
Courtesy Dr. Julie Gralow
1. The left hemisphere excels in language and the right
hemisphere excels in visual spatial tasks. This specialization of
the two hemispheres is known as:
a. split-brain.
b. callosotomy.
c. hemispherectomy.
d. lateralization.
Courtesy Dr. Julie Gralow
52
2. A man involved in a car accident suffered severe brain
trauma. As he recovered, it became clear he was having
difficulty producing speech, even though he could understand
what people were saying to him. It is very likely he had suffered
damage to the left frontal lobe in a part of the brain referred to
as:
a. Wernicke’s area.
b. Broca’s area.
c. the visual field.
d. the corpus callosum.
Courtesy Dr. Julie Gralow
53
3. On rare occasions, medication does not work for people with
severe seizures. In those cases, doctors might suggest a
procedure known as a , which essentially disconnects the right
and left hemispheres.
4. The corpus callosum enables information sharing between the
two hemispheres. In some cases, surgeons sever the corpus
callosum to prevent seizures from spreading between the two
hemispheres. How would you explain to a middle school student
why this surgical procedure is used and how it is helpful?
Courtesy Dr. Julie Gralow
54
The Amazing Brain
NEUROPLASTICITY
Brain undergoes constant alterations
Physical adaptation and repair—even after hemispherectormy
Growth of new connections and reorganization
Stem cells
Responsible for creating new
neurons
HUMAN STEM CELL
Professor Miodrag Stojkovic / Science Source
Courtesy Dr. Julie Gralow
Because stem cells can differentiate into any type of cell in the
body, they have great therapeutic potential.
The cells pictured here are derived from a human embryo, but
stem cells also reside in various adult tissues such as the brain
and bone marrow.
Professor Miodrag Stojkovic/Science Source
55
Across the World
THE PLASTIC BRAINS OF OUR CHILDREN
Children and music
Chinese parents believe that piano instruction for their
kindergarteners will help school performance.
American parents play classical music to unborn fetuses and
how DVDs to their infant and toddler to promote brain
development.
Are these parents right in their assumptions?
Courtesy Dr. Julie Gralow
People with musical training generally score higher on
language, auditory, and overall IQ tests. (CORRELATIONAL
EVIDENCE)
No data demonstrates that listening to music enhances
intelligence.
56
The Amazing Brain
ALL IN YOUR HEAD
Are you a secretive person? How high is your self-esteem?
The answers to these questions lie on the surface of the skull, or
so claimed 19th century phrenologists.
© North Wind Picture Archives / The Image Works
Courtesy Dr. Julie Gralow
The Amazing Brain
TOOLS FOR STUDYING THE BRAIN
Electroencephalogram (EEG)
Computerized Axial Tomography (CAT scan or CT scan)
Positron Emission Tomography (PET)
Magnetic Resonance Imaging (MRI)
Functional Magnetic Resonance Imaging (fMRI)
What are the strengths and limitations of each of these tools?
Courtesy Dr. Julie Gralow
See Table 2.1 and INFORMATICS 2.3 for additional
information.
58
Social Media and Psychology
FACEBOOK IN THE BRAIN
Facebook friends range from zero to 5000, averaging 245.
A preliminary study suggests friend volume may reflex
something about a user’s brain.
There is a correlation between number of Facebook friends and
density of gray matter in areas of brain known for social
interaction and facial recognition.
So…are your Facebook friends a gray matter?
Courtesy Dr. Julie Gralow
STIMULATING BRAIN CELLS MAY BE TRICKIER THAN
WE THOUGHT
Using a new type of optical imaging, Harvard Medical School
researchers observed neurons as they were stimulated by an
electrode.
Electrodes caused sparse strings of neurons, rather than a small
sphere of surrounding neurons.
Findings suggests a much smaller margin of error during brain
surgery and design of neural prosthetics.
Melinda Wenner. Reproduced with permission. Copyright ˝
2010 Scientific American, a division of NatureAmerica, Inc. All
rights reserved.
Electric Surprise
Courtesy Dr. Julie Gralow
1. Scientists hope that in the future they will be able to discover
how we can use stem cells to help people like Brandon and
Christina. The goal would be for doctors to induce the process
of to restore the lost brain tissue.
a. ablation
b. agonists
c. neurogenesis
d. lateralization
Courtesy Dr. Julie Gralow
61
2. You have been asked to set up an experiment to determine if
playing classical music to infants leads to improved cognitive
abilities. What would your independent anddependent variables
be? How would your experimental and control groups be treated
differently?
3. ________ are responsible for creating new neurons.
Courtesy Dr. Julie Gralow
62
The brain is constantly undergoing alterations in response to
experiences and is capable of a certain degree of physical
adaptation and repair. This ability is known as:
a. neuroplasticity
b. phrenology
c. ablation
d. lateralization
Courtesy Dr. Julie Gralow
63
Courtesy Dr. Julie Gralow
The Cortex: A Peek Beneath the Skull
THE CORTEX
Cerebral cortex
Processes information and surrounds nearly all of the brain
structure
Association areas
Involves region of cortex that integrates information from all
over the brain.
What does it require to study the brain?
Look at the above illustration for clues.
Courtesy Dr. Julie Gralow
Cerebral cortex: The wrinkled outermost layer of the cerebrum,
responsible for higher mental functions, such as decision
making, planning, and processing visual information.
Association areas: Regions of the cortex that integrate
information from all over the brain, allowing us to learn, think
in abstract terms, and carry out other intellectual tasks.
What does it require to study the brain?
In order to study the brain,
we must get to it first. Peel away
the scalp and cut away the bony
skull, and you will find still more
layers of protection. Three thin
membranes—the meninges—
provide a barrier to both
physical injury and infection.
Bypass them, and the outermost
layer of the brain, the cortex,
is revealed.
65
THE LOBES: UP CLOSE AND PERSONAL
Courtesy Dr. Julie Gralow
The Cortex: A Peek Beneath the Skull
Courtesy Dr. Julie Gralow
THE LOBES: UP CLOSE AND PERSONAL
67
Phineas Gage and the frontal lobes
In 1848, Gage was impaled by a 3-foot tamping rod through his
cheek, brain, and skull and caused dramatic changes in his
personality.
Fritsch and Hitzig and the motor cortex
By applying mild shock to dogs’ cortex, researchers
demonstrated that motor cortex region involvement in muscle
movement.
Albert Einstein and the parietal lobes
Postmortem comparison of 35 male brain specimens and
Einstein’s brain and found the region of Einstein’s parietal lobe
responsible for visualspatial cognition and mathematical
thinking was 15 percent larger than those of the control group.
The Cortex: A Peek Beneath the Skull
THE LOBES: UP CLOSE AND PERSONAL
Penfield
Used method similar to Fritsch and Hitzig showing which points
along the motor cortex and somatosensory cortex corresponded
to parts of the body
Developed model that often represented by oversimplified
“homunculus”
Courtesy Dr. Julie Gralow
The Motor and
Somatosensory Cortex
PENFIELD’S
MAP
Courtesy Dr. Julie Gralow
This drawing shows how the motor and somatosensory cortex
correspond to the various regions of the body.
Parts of the body that are shown larger, such as the face and
hands, indicate areas of greater motor control or sensitivity.
The size of each body part reflects the amount of cortex
allocated to it.
69
The Cortex: A Peek Beneath the Skull
THE LOBES: UP CLOSE AND PERSONAL
Occipital lobes
Is initial processing site for visual information
Primary visual cortex
Connects to optic nerve where visual information is received
and interpreted
Courtesy Dr. Julie Gralow
1. The major function of the is to organize information among
the other lobes of the brain.
a. parietal lobes
b. frontal lobes
c. corpus callosum
d. temporal lobes
2. The ________ integrate information from all over the brain,
allowing us to learn, have abstract thoughts, and carry out
complex behaviors.
Courtesy Dr. Julie Gralow
71
3. This section introduces the lobes of the cortex and their
associated functions. Create a way to remember the lobes and
their specific functions using a rhyme or another memorization
technique you know.
Courtesy Dr. Julie Gralow
72
4. Phineas Gage suffered a horrific accident in the mid-1800s,
when an explosion sent a metal rod through his brain and out
the top of his skull. Which of the following caused the sudden
change in his personality following the accident?
a. damage to his occipital lobes
b. damage to his temporal lobes
c. damage to his frontal lobes
d. damage to his somatosensory cortex
Courtesy Dr. Julie Gralow
73
Digging Below the Cortex
DRAMA CENTRAL: THE LIMBIC SYSTEM
Limbic system fuels basic drives and processes emotions and
memories.
Stockbyte/Getty Images
Courtesy Dr. Julie Gralow
Digging Below the Cortex: Identify Functions
Courtesy Dr. Julie Gralow
Hippocampus: A pair of seahorse-shaped structures located in
the limbic system; primarily responsible for creating new
memories.
Amygdala: A pair of almond shaped structures in the limbic
system that processes basic emotions, such as fear and
aggression, as well as associated memories.
Thalamus: A structure in the limbic system that processes and
relays sensory information to the appropriate areas of the
cortex.
Hypothalamus: A small structure located below the thalamus
that maintains a constant internal environment within a healthy
range; helps regulate sleep-wake cycles, sexual behavior, and
appetite.
75
Hippocampus
Amygdala
Thalamus
Hypothalamus
Digging Below the Cortex
DEEPER YET: THE BRAINSTEM AND CEREBELLUM
Brainstem
Includes the brain’s core
Extends from spinal cord to forebrain
Forebrain
Involves largest part of brain and includes cerebral cortex and
limbic system
Midbrain
Involves brain stem part involved in arousal levels, responsible
for generating movement patterns in response to sensory input
Courtesy Dr. Julie Gralow
Digging Below the Cortex
BRAINSTEM AND CEREBELLUM
Reticular formation
Involves network of neurons running through the midbrain
Controls levels of arousal and quickly analyzes sensory
information on its way to the cortex
Hindbrain
Pons
Medulla
Cerebellum
Involves muscle coordination and balance
May also affect fine distinctions in cognition
Courtesy Dr. Julie Gralow
Amazing Brains: Amazing People
Three years after his traumatic
brain injury, Brandon celebrated
his marriage to Laura. The couple
recently had their third child, a
daughter named MacCrea Iona.
With her master’s degree in speech–language pathology,
Christina now works full time in Pennsylvania’s public school
system.
Laura Burns
Courtesy, Bucks County Courier Times
Courtesy Dr. Julie Gralow
1. The represents a group of interconnected structures that
process emotions, memories, and basic drives.
a. left hemisphere
b. limbic system
c. corpus callosum
d. superior temporal sulcus
2. The specific part of the brain that processes basic emotions,
such as fear and aggression and the memories associated with
them, is the ______.
Courtesy Dr. Julie Gralow
79
3. How might the specific structures of the limbic system, the
brainstem, and the cerebellum come into play if you were out on
a first date?
4. The primary role of the thalamus is to:
a. relay sensory information.
b. keep the body’s systems in a steady state.
c. generate movement patterns in response to
sensory input.
d. regulate sleep–wake cycles.
Courtesy Dr. Julie Gralow
80

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Courtesy Dr. Julie Gralow1LO 1 Define neuroscience a.docx

  • 1. Courtesy Dr. Julie Gralow 1 LO 1 Define neuroscience and explain its contributions to our understanding of behavior. LO 2 Label the parts of a neuron and describe an action potential. LO 3 Illustrate how neurons communicate with each other. LO 4 Summarize various neurotransmitters and the roles they play in human behavior. LO 5 Recognize the connections between the central and peripheral nervous systems. Courtesy Dr. Julie Gralow LO 6 Evaluate pseudopsychology and its relationship to critical thinking. LO 7 Describe how psychologists use the scientific method. LO 8 Summarize the importance of a random sample. LO 9 Recognize the forms of descriptive research. LO 10 Explain how the experimental method relates to cause and effect. LO 11 Demonstrate an understanding of research ethics. Courtesy Dr. Julie Gralow LO 12 Compare and contrast tools scientists use to study the brain. LO 13 Identify the lobes of the cortex and explain their functions.
  • 2. LO 14 Recognize the association areas and identify their functions. LO 15 Distinguish the structures and functions of the limbic system. LO 16 Distinguish the structures and functions of the brainstem and cerebellum. Courtesy Dr. Julie Gralow Biology and Behavior: Studying the Last Frontier Neuroscience Involves study of the brain and nervous system Biological psychology Focuses on how the brain and other biological systems influence human behavior Contributions Examination of extent of experience-induced neural plasticity Courtesy Dr. Julie Gralow 5 Biology and Behavior: Studying the Last Frontier Brandon Burns poses for a photo at the Marine Corps Recruit Depot in Parris Island, South Carolina in the fall of 2003. The following year, he was shot in the head by an enemy sniper in the Battle of Fallujah. Doctors concluded that some parts of his brain were no longer viable. “They removed part of my skull and dug out the injured part of my brain,” and now, Brandon says, “one third of my
  • 3. brain is gone.” What were the consequences of his injury? Brandon Burns in the military Courtesy Dr. Julie Gralow Neuroscience Contributions Biological psychology 6 Courtesy Dr. Julie Gralow The neuron, the basic building block of the nervous system, has three main components: (1) the cell body, which contains vital cellular structures; (2) bushy dendrites that receive messages from neighboring neurons; and (3) a long, thin axon that sends messages to other neurons through its branchlike terminal buds. James Cavallini/Photo Researchers, Inc. 7 Can you identify the structure of a typical neuron? Courtesy Dr. Julie Gralow Cell body: Region of the neuron that a nucleus containing DNA, protein-producing mechanisms, and other structures that nourish the celi
  • 4. Dendrites: Tiny, branchlike fibers extending from the cell body that receive messages from other neurons and send information in the direction of the cell body Axon: Skinny tubelike structure of a neuron that extends from the cell body, and which sends messages to other neurons. Myeline sheath: Fatty substance that insulates the axon and speeds the transmission of neural messages. Synapse: Tiny gap between a terminal bud of one axon and a neighboring dendrite of the next neuron junction between neurons where communication occurs. 8 Cell body Dendrites Axon Terminal buds Myelin sheath Synapse
  • 5. Biology and Behavior Glia to the Rescue A scanning electron micrograph shows neurons (green) and glia
  • 6. (orange). Glial cells serve as the “glue” of the nervous system, providing cohesion and support for the neurons. Thomas Deerinck, NCMIR Some classes of glial cells Microglia Astrocytes Schwann Thomas Deerinck, NCMIR / Science Source Courtesy Dr. Julie Gralow COMMUNICATION WITHIN NEURONS THE NEURON AT REST 2. THE ACTION POTENTIAL 3. ACTION POTENTIAL TRAVELS LENGTH OF AXON Courtesy Dr. Julie Gralow Communication within neurons Neural communication involves different processes within and between neurons. In this infographic, we follow the electrical action that conveys messages within the neuron, from one end to the other. 1. THE NEURON AT REST Before communication begins, the neuron is “at rest.” Closed channels in the cell membrane prevent some positive ions from entering the cell, and the inside of the cell is slightly more
  • 7. negative than the charge outside. At –70 mV, the cell is at its resting potential. 2. THE ACTION POTENTIAL This graph shows the characteristic electrical trace of the action potential. When the neuron is stimulated, positive ions enter the cell, making the axon less negative (A). When the charge reaches threshold (–55 mV), an action potential is triggered. Positive ions flood the cell, quickly reversing the charge from negative to positive (B). Afterward, the cell is restored to resting potential (C). ACTION POTENTIAL TRAVELS LENGTH OF AXON The action potential occurring in one axon segment causes a voltage change in the next, initiating an entirely new action potential there. This sequential action travels along the axon like a wave, carrying the message from axon hillock to terminal buds. 10 Biology and Behavior: Studying the Last Frontier COMMUNICATION WITHIN AND BETWEEN Resting potential Electrical potential of cell at rest Solution s on either side of the membrane wall come into equilibrium; slightly more negative charge inside Courtesy Dr. Julie Gralow
  • 8. Biology and Behavior: Studying the Last Frontier COMMUNICATION WITHIN AND BETWEEN Action potential Involves spike in electrical energy that passes through the axon of a neuron, the purpose of which is to convey information Is all-or-none Every time a segment of the axon fires Positive sodium ions flood in from the outside of the cell, while the prior segment returns to its resting potential, all along the length of the axon to its end Courtesy Dr. Julie Gralow Biology and Behavior: Studying the Last Frontier COMMUNICATION WITHIN AND BETWEEN Excitatory signals Occur when enough combine, sending neurons signal the receiving neuron to pass along message Inhibitory signals Inhibit neuron from releasing a signal through the axon
  • 9. Courtesy Dr. Julie Gralow Biology and Behavior: COMMUNICATION WITHIN AND BETWEEN Myelin sheath insulates and protects the tiny spikes in electricity happening inside the axon. Action potential “skips” over the segments of myelin, hopping from one node to the next, instead of traversing the entire length of the axon. MYELIN Protein that envelops and insulates the axon, facilitating faster transmission of the impulse. Jean-Claude Revy, ISM/Phototake Courtesy Dr. Julie Gralow Biology and Behavior: Studying the Last Frontier COMMUNICATION BETWEEN Neurotransmitters Chemical messengers that neurons use to communicate at the synapse
  • 10. Receptor sites Location where neurotransmitters attach on the receiving side of the synaptic gap Reuptake Process by which neurotransmitters are reabsorbed by the sending terminal bud Courtesy Dr. Julie Gralow Biology and Behavior Axon terminal of a sending neuron interacts with the dendrites of a receiving neuron by releasing chemical messengers (neurotransmitters) into the synapse. Once the neurotransmitters migrate across the gap and latch onto the dendrite’s receptor sites, the message has been conveyed. The Synapse Carol and Mike Werner/Science Source Courtesy Dr. Julie Gralow Biology and Behavior:
  • 11. Studying the Last Frontier COMMUNICATION WITHIN AND BETWEEN Reuptake Occurs when neurotransmitters are reabsorbed by the sending bud Diffusion Occurs when neurotransmitters are not reabsorbed and drift out of the synaptic gap Courtesy Dr. Julie Gralow Courtesy Dr. Julie Gralow Biology and Behavior: Studying the Last Frontier NEUOTRANSMITTERS Acetylcholine Relays messages from motor neurons to muscles, enabling movement; involved in memory Too much = spasms; too little = paralysis Glutamate
  • 12. Makes neurons fire; central role in memory and learning Too much = strokes; too little = symptoms of schizophrenia GABA Inhibits neurotransmitter firing; contributes to motor control, vision Courtesy Dr. Julie Gralow Biology and Behavior: Studying the Last Frontier NEUOTRANSMITTERS Norepinephrine Has variety of effects in CNS; helps body prepare for stress Serotonin Plays key role in controlling appetite, aggression, and mood; regulates sleep and breathing Dopamine Plays role in modulating mood; plays central role in positive reinforcement and dependency Courtesy Dr. Julie Gralow Biology and Behavior: Studying the Last Frontier
  • 13. NEUOTRANSMITTERS Endorphins Regulates secretion of other neurotransmitter; naturally produced opioids; reduces pain and elevates mood Agonists Interfere at level of synapse; increase normal neurotransmitter activity Antagonists Interfere at level of synapse; decrease normal neurotransmitter activity Courtesy Dr. Julie Gralow Biology and Behavior NEUOTRANSMITTERS Caffeine Blocks receptors for adenosine Increases activity in branch of nervous system serving the body istockphoto/thinkstock Courtesy Dr. Julie Gralow
  • 14. 1. Many axons are surrounded by a ______ , which is a fatty substance that insulates the axon. 2. When Brandon was injured, played an important role in his recovery by defending against infection and inflammation of the brain, as well as holding neurons together and maintaining the structure of the nervous system. a. glial cells b. dendrites c. action potentials d. sodium ions Courtesy Dr. Julie Gralow 23 3. ________are released into the ________when an action potential reaches the branches of the terminal buds. Sodium ions; synaptic gap Neurotransmitters; synaptic gap Potassium ions; cell membrane Neurotransmitters; sodium gates
  • 15. 4. Neural communication is very complicated. Draw a diagram depicting the process of neural communication, then explain it to yourself while looking at what you have drawn. Courtesy Dr. Julie Gralow 24 The Supporting Systems INFRASTRUCTURE Brain needs supporting infrastructure to carry out directives and relay essential information from outside Central nervous system (CNS) Peripheral nervous system (PNS) Courtesy Dr. Julie Gralow Central nervous system (CNS): A major component of the human nervous system that includes the brain and spinal cord. Peripheral nervous system (PNS): The part of the nervous system that connects the central nervous system to the rest of the body. 25
  • 16. THE SUPPORTING SYSTEMS Overview of the Nervous System The nervous system is made up of the central nervous system, which includes the brain and spinal cord, and the peripheral nervous system. moodboard/Alamy moodboard / Alamy Courtesy Dr. Julie Gralow 26 The Supporting Systems Spinal cord Includes bundle of neurons Allows communication between the brain and the peripheral nervous system Connects with the body’s muscles, glands, and organs
  • 17. Courtesy Dr. Julie Gralow The Supporting Systems Courtesy Dr. Julie Gralow CONNECTIONS BETWEEN CNS AND PNS 28 Sensory neurons Receive information about the environment from the sensory systems and convey this to the brain for processing Motor neurons Carry information from CNS to produce movement; provide mechanism regulated by spinal cord and brain Interneurons
  • 18. Resides in brain and spinal cord; act as bridges connecting sensory and motor neurons Without any input from the brain, the spinal cord neurons are capable of creating some simple reflexive behavior. While the spinal reflex occurs, sensory neurons also send messages to the brain, letting it know what has happened. THE SPINAL CORD AND REFLEX ARC Courtesy Dr. Julie Gralow Reflex arc: An automatic response to a sensory stimulus, such as the “knee jerk” reaction; a simple pathway of communication
  • 19. from sensory neurons through interneurons in the spinal cord back out through motor neurons. 29 Try This Test your knowledge of the reflex arc using Brandon as an example. As you recall, Brandon’s brain injury led to paralysis on the right side of his body. What do you think would happen if a doctor tapped on his right knee—would he experience a reflex? Courtesy Dr. Julie Gralow What Lies Beyond: The Peripheral Nervous System Peripheral nervous system Includes all neurons not in CNS Involves neurons that are bundled together to carry signals throughout body Nerves Act as primary communication system for PNS Supply CNS with information about body’s environment
  • 20. Courtesy Dr. Julie Gralow What Lies Beyond: The Peripheral Nervous System SOMATIC NERVOUS SYSTEM Characteristics Involves branch of the parasympathetic nervous system Includes sensory nerves and motor nerves Gathers information from sensory receptors Controls the skeletal muscles responsible for voluntary movement Courtesy Dr. Julie Gralow What Lies Beyond: The Peripheral Nervous System AUTONOMIC NERVOUS SYSTEM Characteristics Regulates involuntary activity Has two divisions involved in physiological responses to stress or crisis situations Sympathetic nervous system Parasympathetic nervous system
  • 21. Courtesy Dr. Julie Gralow Sympathetic nervous system: The division of the autonomic nervous system that mobilizes the "fight-or-flight” response to stressful or crisis situations. Parasympathetic nervous system: The division of the autonomic nervous system that orchestrates the "rest-anddigest”response to bring the body back to a noncrisis mode. 33 THE SYMPATHETIC AND PARASYMPATHETIC NERVOUS SYSTEM PhotoObjects.net/Thinkstock Courtesy Dr. Julie Gralow The autonomic nervous system has two divisions, the sympathetic and parasympathetic nervous systems. In a stressful situation, the sympathetic nervous system initiates the “fight-orflight” response. The parasympathetic nervous system calms the body when the stressful situation has passed. PhotoObjects.net/Thinkstock
  • 22. 34 What Lies Beyond: The Peripheral Nervous System TEND AND BEFRIEND Female response to stress Many women have inclination to direct energy toward nurturing and forging social bonds as a stress response Courtesy Dr. Julie Gralow Think Again MALE BRAIN, FEMALE BRAIN Studies suggest gender stereotypes can influence performance in math and science. Research also shows that male and female brains are far more alike than they are different, but... Certain regions of the limbic cortex and the frontal lobes were larger in women Areas of the parietal cortex, the amygdala, and hypothalamus were larger in men So is nature or nurture responsible for gender imbalance in math and the science?
  • 23. Courtesy Dr. Julie Gralow Research shows that male and female brains are far more alike than they are different, but some anatomical and functional differences exist. 36 The Endocrine System and Its Slowpoke Messengers ENDOCRINE SYSTEM Hormones Pituitary gland Thyroid gland Adrenal glands Can you define each of these? Courtesy Dr. Julie Gralow Endocrine system: Communication system that uses glands, rather than neurons to convey messages. Hormones: Chemical messengers released into the bloodstream that influence mood, cognition, appetite, and many other
  • 24. processes and behaviors. Pituitary gland: The pea-sized gland located in the center of the brain just under the hypothalamus; secretes hormones that dictate the release of hormones by other glands; known as the master gland. Thyroid gland: Gland of the endocrine system that regulates the rate of metabolism by secreting thyroxin. Adrenal glands: Part of the endocrine system involved in responses to stress as well as the regulation of salt balance. 37 The Endocrine System left: (face) Hemera/Thinkstock, (body) Yuri Arcurs; right: Asias elects/Getty Images Courtesy Dr. Julie Gralow This system of glands communicates within the body by secreting hormones directly into the bloodstream. left: (face) Hemera/Thinkstock, (body) Yuri Arcurs; right: Asiaselects/Getty Images 38 The Endocrine System and Its
  • 25. Slowpoke Messengers OTHER ENDOCRINE GLANDS AND ORGANS Pineal gland Secretes melatonin Pancreas Secretes insulin Ovaries and testes Secrete sex hormones Courtesy Dr. Julie Gralow 1. ________ carry information from the central nervous system to activate various parts of the body, such as muscles and glands. a. Interneurons b. Dendrites c. Sensory neuron d. Motor neurons Courtesy Dr. Julie Gralow 40 2. When a stimulus causes an involuntary response, we refer to
  • 26. it as a reflex arc; the simple communication pathway goes from a sensory neuron through interneurons in the and back out through motor neurons. a. brain b. spinal cord c. axon hillock d. nodes of Ranvier Courtesy Dr. Julie Gralow 41 3. The ________ gland, located in the center of the brain, just under the hypothalamus, is in charge of the endocrine system. 4. When confronted with a potentially threatening situation, the sympathetic nervous system sometimes prepares for “fight or flight” and/or “tend and befriend.” How would you explain these two very different responses using the evolutionary perspective? Courtesy Dr. Julie Gralow
  • 27. 42 The Hemispheres RIGHT BRAIN, LEFT BRAIN: THE TWO HEMISPHERES Cerebrum Includes largest, most highly developed part of brain Involved in intelligence, personality, thinking, perceiving, planning and organization, language, sensation, motor functions Divided into right and left hemispheres and covered by corpus callosum Courtesy Dr. Julie Gralow Two Hemispheres The cerebrum looks like a walnut with its two wrinkled halves. Regions of the left and right hemispheres specialize in different activities, but the two sides of the brain are constantly communicating and collaborating. Science Source/Photo Researchers, Inc. Colorization by: Eric Cohen The right hemisphere controls the left side of the body, and the left hemisphere controls the right.
  • 28. This explains why Brandon, who was shot on the left side of his head, suffered paralysis and loss of sensation on the right half of his body. Science Source/Photo Researchers, Inc. Colorization by: Eric Cohe Courtesy Dr. Julie Gralow The Hemispheres HEMISPHERECTOMY Christina Santhouse relaxes with her mother at Johns Hopkins, where she had a dramatic brain surgery known as a hemispherectomy. Prior to the operation, Christina experienced over 100 seizures a day. William Johnson Courtesy Dr. Julie Gralow The Hemispheres SPLIT BRAIN Hemispherectomies Exceptionally rare; last resort Callostomies (Split-brain operations)
  • 29. Right and left hemisphere disconnected Both hemispheres Intact After hemispherectomy MRI SCAN Medical Body Scans / Science Source Courtesy Dr. Julie Gralow The Split-Brain Experiment The image to the right shows a top view of the corpus callosum, the bundle of neurons linking the right and left hemispheres. When the corpus callosum s severed, we can easily see functional differences between the two sides of the brain. Studies of people who have undergone this procedure are is shown here. Terence H. Williams, Nedzad Gluhbegovic/Wolters Kluwer
  • 30. 1 3 2 Courtesy Dr. Julie Gralow Information presented to right visual field is processed in left hemisphere where language processing occurs. Subject can speak the answer. 2. Information presented to left visual field is processed in right hemisphere. Subject can’t use language to say what he was shown. 3. The subject can touch the correct object even if he can’t say what has been projected in his left visual field. The subject uses his left hand, which is controlled by the right hemisphere, where the visual information has been processed. 47 The Hemispheres LATERALIZATION Generalization Left hemisphere plays a crucial role in language processing and right hemisphere plays a crucial role in managing visual spatial tasks
  • 31. But Hemispheres constantly integrate and share information Courtesy Dr. Julie Gralow The Hemispheres LANGUAGE AND THE LEFT Handedness and dominance Left hemisphere controls language in most people; do not necessarily correspond to handedness Language dominance Broca’s area Wernicke’s area Speak Again Brandon works on his pronunciation in front of a mirror during a speech therapy session at the Memphis VA hospital. You can see the extent of his injury on the left side of his head. Upon awaking from his coma, Brandon could not articulate a single word. Today, he can hold his own in complex conversations. A.J. Wolfe The Commercial Appeal Courtesy Dr. Julie Gralow
  • 32. The Hemispheres LANGUAGE AREA AND THE BRAIN Broca’s area Wernicke’s area Can you identify the role each structure plays in language production and comprehension? Wernicke’s area Broca’s area Courtesy Dr. Julie Gralow Broca’s area: An area of the cortex that is critical for speech production. Wernicke’s area: A region of the cortex that plays a pivotal role in language comprehension. 50 The Hemispheres THE ROLE OF THE RIGHT Research: Right hemisphere More proficient in some visual tasks Critical for understanding abstract and humorous use of language Better for following conversations that change topics
  • 33. Important for recognizing faces Courtesy Dr. Julie Gralow 1. The left hemisphere excels in language and the right hemisphere excels in visual spatial tasks. This specialization of the two hemispheres is known as: a. split-brain. b. callosotomy. c. hemispherectomy. d. lateralization. Courtesy Dr. Julie Gralow 52 2. A man involved in a car accident suffered severe brain trauma. As he recovered, it became clear he was having difficulty producing speech, even though he could understand what people were saying to him. It is very likely he had suffered damage to the left frontal lobe in a part of the brain referred to as:
  • 34. a. Wernicke’s area. b. Broca’s area. c. the visual field. d. the corpus callosum. Courtesy Dr. Julie Gralow 53 3. On rare occasions, medication does not work for people with severe seizures. In those cases, doctors might suggest a procedure known as a , which essentially disconnects the right and left hemispheres. 4. The corpus callosum enables information sharing between the two hemispheres. In some cases, surgeons sever the corpus callosum to prevent seizures from spreading between the two hemispheres. How would you explain to a middle school student why this surgical procedure is used and how it is helpful? Courtesy Dr. Julie Gralow 54
  • 35. The Amazing Brain NEUROPLASTICITY Brain undergoes constant alterations Physical adaptation and repair—even after hemispherectormy Growth of new connections and reorganization Stem cells Responsible for creating new neurons HUMAN STEM CELL Professor Miodrag Stojkovic / Science Source Courtesy Dr. Julie Gralow Because stem cells can differentiate into any type of cell in the body, they have great therapeutic potential. The cells pictured here are derived from a human embryo, but stem cells also reside in various adult tissues such as the brain and bone marrow. Professor Miodrag Stojkovic/Science Source 55
  • 36. Across the World THE PLASTIC BRAINS OF OUR CHILDREN Children and music Chinese parents believe that piano instruction for their kindergarteners will help school performance. American parents play classical music to unborn fetuses and how DVDs to their infant and toddler to promote brain development. Are these parents right in their assumptions? Courtesy Dr. Julie Gralow People with musical training generally score higher on language, auditory, and overall IQ tests. (CORRELATIONAL EVIDENCE) No data demonstrates that listening to music enhances intelligence. 56 The Amazing Brain ALL IN YOUR HEAD Are you a secretive person? How high is your self-esteem? The answers to these questions lie on the surface of the skull, or
  • 37. so claimed 19th century phrenologists. © North Wind Picture Archives / The Image Works Courtesy Dr. Julie Gralow The Amazing Brain TOOLS FOR STUDYING THE BRAIN Electroencephalogram (EEG) Computerized Axial Tomography (CAT scan or CT scan) Positron Emission Tomography (PET) Magnetic Resonance Imaging (MRI) Functional Magnetic Resonance Imaging (fMRI) What are the strengths and limitations of each of these tools? Courtesy Dr. Julie Gralow See Table 2.1 and INFORMATICS 2.3 for additional information. 58 Social Media and Psychology FACEBOOK IN THE BRAIN
  • 38. Facebook friends range from zero to 5000, averaging 245. A preliminary study suggests friend volume may reflex something about a user’s brain. There is a correlation between number of Facebook friends and density of gray matter in areas of brain known for social interaction and facial recognition. So…are your Facebook friends a gray matter? Courtesy Dr. Julie Gralow STIMULATING BRAIN CELLS MAY BE TRICKIER THAN WE THOUGHT Using a new type of optical imaging, Harvard Medical School researchers observed neurons as they were stimulated by an electrode. Electrodes caused sparse strings of neurons, rather than a small sphere of surrounding neurons. Findings suggests a much smaller margin of error during brain surgery and design of neural prosthetics. Melinda Wenner. Reproduced with permission. Copyright ˝ 2010 Scientific American, a division of NatureAmerica, Inc. All rights reserved.
  • 39. Electric Surprise Courtesy Dr. Julie Gralow 1. Scientists hope that in the future they will be able to discover how we can use stem cells to help people like Brandon and Christina. The goal would be for doctors to induce the process of to restore the lost brain tissue. a. ablation b. agonists c. neurogenesis d. lateralization Courtesy Dr. Julie Gralow 61 2. You have been asked to set up an experiment to determine if playing classical music to infants leads to improved cognitive abilities. What would your independent anddependent variables be? How would your experimental and control groups be treated differently?
  • 40. 3. ________ are responsible for creating new neurons. Courtesy Dr. Julie Gralow 62 The brain is constantly undergoing alterations in response to experiences and is capable of a certain degree of physical adaptation and repair. This ability is known as: a. neuroplasticity b. phrenology c. ablation d. lateralization Courtesy Dr. Julie Gralow 63 Courtesy Dr. Julie Gralow The Cortex: A Peek Beneath the Skull
  • 41. THE CORTEX Cerebral cortex Processes information and surrounds nearly all of the brain structure Association areas Involves region of cortex that integrates information from all over the brain. What does it require to study the brain? Look at the above illustration for clues. Courtesy Dr. Julie Gralow Cerebral cortex: The wrinkled outermost layer of the cerebrum, responsible for higher mental functions, such as decision making, planning, and processing visual information. Association areas: Regions of the cortex that integrate information from all over the brain, allowing us to learn, think in abstract terms, and carry out other intellectual tasks.
  • 42. What does it require to study the brain? In order to study the brain, we must get to it first. Peel away the scalp and cut away the bony skull, and you will find still more layers of protection. Three thin membranes—the meninges— provide a barrier to both physical injury and infection. Bypass them, and the outermost layer of the brain, the cortex, is revealed. 65 THE LOBES: UP CLOSE AND PERSONAL Courtesy Dr. Julie Gralow The Cortex: A Peek Beneath the Skull Courtesy Dr. Julie Gralow THE LOBES: UP CLOSE AND PERSONAL
  • 43. 67 Phineas Gage and the frontal lobes In 1848, Gage was impaled by a 3-foot tamping rod through his cheek, brain, and skull and caused dramatic changes in his personality. Fritsch and Hitzig and the motor cortex By applying mild shock to dogs’ cortex, researchers demonstrated that motor cortex region involvement in muscle movement. Albert Einstein and the parietal lobes Postmortem comparison of 35 male brain specimens and Einstein’s brain and found the region of Einstein’s parietal lobe responsible for visualspatial cognition and mathematical
  • 44. thinking was 15 percent larger than those of the control group. The Cortex: A Peek Beneath the Skull THE LOBES: UP CLOSE AND PERSONAL Penfield Used method similar to Fritsch and Hitzig showing which points along the motor cortex and somatosensory cortex corresponded to parts of the body Developed model that often represented by oversimplified “homunculus” Courtesy Dr. Julie Gralow
  • 45. The Motor and Somatosensory Cortex PENFIELD’S MAP Courtesy Dr. Julie Gralow This drawing shows how the motor and somatosensory cortex correspond to the various regions of the body. Parts of the body that are shown larger, such as the face and hands, indicate areas of greater motor control or sensitivity. The size of each body part reflects the amount of cortex allocated to it. 69 The Cortex: A Peek Beneath the Skull THE LOBES: UP CLOSE AND PERSONAL Occipital lobes Is initial processing site for visual information Primary visual cortex Connects to optic nerve where visual information is received and interpreted
  • 46. Courtesy Dr. Julie Gralow 1. The major function of the is to organize information among the other lobes of the brain. a. parietal lobes b. frontal lobes c. corpus callosum d. temporal lobes 2. The ________ integrate information from all over the brain, allowing us to learn, have abstract thoughts, and carry out complex behaviors. Courtesy Dr. Julie Gralow 71 3. This section introduces the lobes of the cortex and their associated functions. Create a way to remember the lobes and their specific functions using a rhyme or another memorization technique you know. Courtesy Dr. Julie Gralow
  • 47. 72 4. Phineas Gage suffered a horrific accident in the mid-1800s, when an explosion sent a metal rod through his brain and out the top of his skull. Which of the following caused the sudden change in his personality following the accident? a. damage to his occipital lobes b. damage to his temporal lobes c. damage to his frontal lobes d. damage to his somatosensory cortex Courtesy Dr. Julie Gralow 73 Digging Below the Cortex DRAMA CENTRAL: THE LIMBIC SYSTEM Limbic system fuels basic drives and processes emotions and memories. Stockbyte/Getty Images Courtesy Dr. Julie Gralow
  • 48. Digging Below the Cortex: Identify Functions Courtesy Dr. Julie Gralow Hippocampus: A pair of seahorse-shaped structures located in the limbic system; primarily responsible for creating new memories. Amygdala: A pair of almond shaped structures in the limbic system that processes basic emotions, such as fear and aggression, as well as associated memories. Thalamus: A structure in the limbic system that processes and relays sensory information to the appropriate areas of the cortex. Hypothalamus: A small structure located below the thalamus that maintains a constant internal environment within a healthy range; helps regulate sleep-wake cycles, sexual behavior, and appetite. 75 Hippocampus Amygdala
  • 49. Thalamus Hypothalamus Digging Below the Cortex DEEPER YET: THE BRAINSTEM AND CEREBELLUM Brainstem Includes the brain’s core Extends from spinal cord to forebrain Forebrain Involves largest part of brain and includes cerebral cortex and limbic system Midbrain
  • 50. Involves brain stem part involved in arousal levels, responsible for generating movement patterns in response to sensory input Courtesy Dr. Julie Gralow Digging Below the Cortex BRAINSTEM AND CEREBELLUM Reticular formation Involves network of neurons running through the midbrain Controls levels of arousal and quickly analyzes sensory information on its way to the cortex Hindbrain Pons Medulla Cerebellum Involves muscle coordination and balance May also affect fine distinctions in cognition Courtesy Dr. Julie Gralow Amazing Brains: Amazing People Three years after his traumatic brain injury, Brandon celebrated
  • 51. his marriage to Laura. The couple recently had their third child, a daughter named MacCrea Iona. With her master’s degree in speech–language pathology, Christina now works full time in Pennsylvania’s public school system. Laura Burns Courtesy, Bucks County Courier Times Courtesy Dr. Julie Gralow 1. The represents a group of interconnected structures that process emotions, memories, and basic drives. a. left hemisphere b. limbic system c. corpus callosum d. superior temporal sulcus 2. The specific part of the brain that processes basic emotions, such as fear and aggression and the memories associated with them, is the ______. Courtesy Dr. Julie Gralow
  • 52. 79 3. How might the specific structures of the limbic system, the brainstem, and the cerebellum come into play if you were out on a first date? 4. The primary role of the thalamus is to: a. relay sensory information. b. keep the body’s systems in a steady state. c. generate movement patterns in response to sensory input. d. regulate sleep–wake cycles. Courtesy Dr. Julie Gralow 80