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In-situ Particle Sizer
15/08/2016
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 2|
Particle size
analysis
Particle shape
analysis
process
analysis
Particle
quantity
statistics
Online PAT sensor
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 3|
Dry, wet
Integrated
Real time online
measure
high resolution
High-precision
Advantages
Sample original
concentration,
No need to dilute
Customize
Based on statistical analysis, data reliability
Sensors can be loaded directly into the
reactor or pipe
 No need to sample
 Online operation can be applied to the Petri
dish, beaker, reactor etc.
 Process stability control
 Rapid development of new formula
24h high quality production
ADVANTAGES
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 4|
1999
LSRA
Laser scanning
analysis
Fingerprint display,
detection of internal
changes in the
particle system
2000
PMS
Particle monitoring
system
Suitable for process
control and Improvement
50-300 μm
2002
ECA
Emulsion
characteristics analysis
Analysis of liquid
droplets in emulsion or
slurry0.5-125μm
2004
PAT
On-line particle analysis
Depth selective focus,
real-time online
measurement2-
4000μm
Development History
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 5|
IPAS
Year 2006
01
IMAS
Year 2010
02
APAS
Year 2011
03
On-line particle analysis system
Depth selective focus, collect and analyze the particle signal
0.5-2000μm
Online shape analysis system
Particle shape, roughness and particle size measurement are
suitable for dynamic crystallization process and polymerization
process ,0.5-2000 μm
Advanced particle analysis system
On line particle shape, particle size measurement
0.5-4000μm
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 6|
Sensor
1D dynamic scattering system
Technical
Principle
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 7|
Rotating annular focus
2D rotating ring scattering system
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 8|
ORM 3D optical back reflection measurement
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 9|
Multiple zoom scanning
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 10|
flight time ToF
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 11|
Product features
1、 Sapphire Window
2、 focusing lens
3、 Rotating optical system
4、 Coupling lens
5、 single mode fiber
6、 Optical fiber connector
7、 Active focus system
Sensor basic structure
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 12|
Dark particle optics project—— Super Laser
Lifting temperature’s range from 120 ℃ to 300℃
Lifting pressure’s range from vacuum to 300bars
Vibration and ultrasonic dispersion are suitable.
Can be used in high temperature, high pressure and high viscosity
measurement environment, dry wet integrated integration
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 13|
Düsseldorf, 24.02.05
mm a b c d
Sensor 740 332 30 60
Sensor 440 230 30 60
Sensor 375 180 25 53
Sensor 375 180 19 53
Sensor 320 200 7,85 24,5
a
b
c d
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 14|
Parameter Malvern TRILOS
Particle Principle Laser Diffraction 3D optical back
reflection
Shape principle Static automatic
imaging system
Multiple zoom scan
optical system Red Light: Max 4mW
He-Ne,632.8nm
Blue Light: Max 10
mW LED,470 nm
Customizable laser
light source
Particle Size Range 0.1 - 2000 μm 0.12 - 4000 μm
Temperature Range 10 ℃ - 70 ℃ -90 ℃ - 300 ℃
Pressure Range Vaccu-10 bar Vaccu-300 bar
Fiber Length 500m 300m
Technical
Parameter
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 15|
Installation
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 16|
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 17|
Crystallization BioprocessMud / Emulsion
PharmacyFood Fine Chemicals
Application
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 18|
Application
Case
Algal size
distribution
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 19|
Cell viability analysis
Particle Shape analysis——
E. coli and yeast
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 20|
Dispersion stability analysis
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 21|
Dispersion Stability Analysis
Unstable emulsion system stable emulsion system
Application Case
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 22|
Process
monitoring
analysis
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 23|
Different concentrations of
tobacco cell differentiation
15/08/2016 PROPERTY OF TRILOS CORPORATIONS 24|

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Trilos In-situ Particle Sizer

  • 2. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 2| Particle size analysis Particle shape analysis process analysis Particle quantity statistics Online PAT sensor
  • 3. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 3| Dry, wet Integrated Real time online measure high resolution High-precision Advantages Sample original concentration, No need to dilute Customize Based on statistical analysis, data reliability Sensors can be loaded directly into the reactor or pipe  No need to sample  Online operation can be applied to the Petri dish, beaker, reactor etc.  Process stability control  Rapid development of new formula 24h high quality production ADVANTAGES
  • 4. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 4| 1999 LSRA Laser scanning analysis Fingerprint display, detection of internal changes in the particle system 2000 PMS Particle monitoring system Suitable for process control and Improvement 50-300 μm 2002 ECA Emulsion characteristics analysis Analysis of liquid droplets in emulsion or slurry0.5-125μm 2004 PAT On-line particle analysis Depth selective focus, real-time online measurement2- 4000μm Development History
  • 5. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 5| IPAS Year 2006 01 IMAS Year 2010 02 APAS Year 2011 03 On-line particle analysis system Depth selective focus, collect and analyze the particle signal 0.5-2000μm Online shape analysis system Particle shape, roughness and particle size measurement are suitable for dynamic crystallization process and polymerization process ,0.5-2000 μm Advanced particle analysis system On line particle shape, particle size measurement 0.5-4000μm
  • 6. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 6| Sensor 1D dynamic scattering system Technical Principle
  • 7. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 7| Rotating annular focus 2D rotating ring scattering system
  • 8. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 8| ORM 3D optical back reflection measurement
  • 9. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 9| Multiple zoom scanning
  • 10. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 10| flight time ToF
  • 11. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 11| Product features 1、 Sapphire Window 2、 focusing lens 3、 Rotating optical system 4、 Coupling lens 5、 single mode fiber 6、 Optical fiber connector 7、 Active focus system Sensor basic structure
  • 12. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 12| Dark particle optics project—— Super Laser Lifting temperature’s range from 120 ℃ to 300℃ Lifting pressure’s range from vacuum to 300bars Vibration and ultrasonic dispersion are suitable. Can be used in high temperature, high pressure and high viscosity measurement environment, dry wet integrated integration
  • 13. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 13| Düsseldorf, 24.02.05 mm a b c d Sensor 740 332 30 60 Sensor 440 230 30 60 Sensor 375 180 25 53 Sensor 375 180 19 53 Sensor 320 200 7,85 24,5 a b c d
  • 14. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 14| Parameter Malvern TRILOS Particle Principle Laser Diffraction 3D optical back reflection Shape principle Static automatic imaging system Multiple zoom scan optical system Red Light: Max 4mW He-Ne,632.8nm Blue Light: Max 10 mW LED,470 nm Customizable laser light source Particle Size Range 0.1 - 2000 μm 0.12 - 4000 μm Temperature Range 10 ℃ - 70 ℃ -90 ℃ - 300 ℃ Pressure Range Vaccu-10 bar Vaccu-300 bar Fiber Length 500m 300m Technical Parameter
  • 15. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 15| Installation
  • 16. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 16|
  • 17. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 17| Crystallization BioprocessMud / Emulsion PharmacyFood Fine Chemicals Application
  • 18. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 18| Application Case Algal size distribution
  • 19. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 19| Cell viability analysis Particle Shape analysis—— E. coli and yeast
  • 20. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 20| Dispersion stability analysis
  • 21. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 21| Dispersion Stability Analysis Unstable emulsion system stable emulsion system Application Case
  • 22. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 22| Process monitoring analysis
  • 23. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 23| Different concentrations of tobacco cell differentiation
  • 24. 15/08/2016 PROPERTY OF TRILOS CORPORATIONS 24|