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Herbal Drug
Technology
Prepared By: Ms. Sweta Kamboj
Assistant Professor
GGSCOP
Herbs As
Raw
Materials
• Introduction:
• The interest of people in herbal
medicines has increased significantly
in both developing and developed
countries.
• There is a great demand for these
herbs, hence there is a need to adopt
systematic scientific methods for
their selection, cultivation,
collection, processing and ensure the
quality, purity, safety, potency and
develop modern methods for their
quality control so that maximum
benefit is obtained from these herbal
medicines.
Herb
• It consist of a plant or any part of the plant
• Which include entire aerial part leaf, flower, fruit, seed, bark, root,
rhizome, tuber or other plant parts.
• Herbal Medicine
• The definition of herbal medicine is the use of plants to prevent and treat
an illness, or to achieve good health as well as the drugs or a plant or plant
part or an extract or mixture of these and tinctures that are used.
Herbal
Medicinal
Products
• These are the medicinal products
which contain exclusive herbal
drugs or herbal drug preparations
which are made from one or more
herbs.
• Where the active ingredient consists
exclusively of herbal substances or
herbal preparations
• The term herbal substances denotes
whole or parts of plants, algae,
fungi. The material is usually dried
but sometimes fresh, and is defined
by specifying the species full
scientific name and the plant part
used.
Herbal Drug
Preparations
• Herbal preparations are the basis for finished herbal products and may
include comminuted or powdered herbal materials, or extracts, tinctures
and fatty oils of herbal materials.
• They are produced by extraction with various solvents (polar to non-polar)
• Purification
• Fractionation
• Concentration and other physical and biological process
Processing
of Herbal
Materials
Collection of
drugs
Time of collection
Harvesting
SOURCES OF HERBS SELECTION, IDENTIfiCATION
AND AUTHENTICATION OF
HERBAL MATERIALS
PROCESSING OF HERBAL
RAW MATERIAL
Sources
of Herbs
• Wild source
• Cultivated
source
Wild
Source
Forests
Plains
river banks
Advantages
Obtaining herbs from wild source is easy
Economical
Less time consuming
Low cost of Labour
Disadvantages
• Unpredictable quality
• The plants are not uniform in their
growth and yielding characteristics
• Modern techniques cannot be applied
for increasing the yield Chances of
depletion of raw material from the field.
Cultivated source
• In cultivation we can apply modern techniques such as-
• Tissue culture
• Genetic engineering
• Hybridization
• Germ plasm
Advantages
Quality and purity is ensured
Better yield and more profit
Ensure regular supply of raw
material
Application of modern
scientific technique is possible
Selection
of herbal
materials
Techniques and methods for
selecting herbal materials-
Randomised approach
Ecological approach
Chemosystematic approach
Ethnoguided approach
Identification of
herbal materials
• Botanical identity
• Specimens
• Seeds and other propagation materials
• Macroscopic characters
• Microscopic characters
• Chromatographic procedures
• Chemical reaction
Authentication of
herbal materials
The steps involved in authentication
are:
• Taxonomic method
• Herbarium coupon sample
• Macroscopic method
• Microscopic method
• Physicochemical method
• Spectroscopic method
• Chromatographic method
• Chemical fingerprinting
• Molecular markers
Processing
of Herbal
Raw
Material
 Primary Processing
• Garbling
• Washing
• Parboiling
• Leaching
• Drying
 Secondary Processing
• Cutting
• Baking
• Boiling
• Stir Frying
• Fumigation
• Extraction
Biodynamic
Agriculture(Organic
Farming Technique)
• GAP- Good Agriculture practices
in which we increase the
productivity of medicinal plants
and crop.
The main objective of GAP
• To improve the quality, safety and
effectiveness of final herbal
product.
• Guide the formation of national
monograph for medicinal plant and
related standard operating
procedure.
• Support cultivation and collection
of medicinal plant of good quality
in order to respect and support the
protection of medicinal plant and
environment.
Guidelines
for GAP of
Medicinal
Plants
Seeds and Propagation material
• Identified botanically, indicating
plant verity, cultivar, chemo type
and its origin
• Material should be 100% traceable
• The parent material of vegetative
part used in organic production
should be certified and
authentically organic
Cultivation
• Depending upon the method of
cultivation
• To avoid environmental
disturbance care should be taken
• Soil and Fertilization
• Medicinal and Aromatic plants should not be
grown in soils that are contaminated by the
sludge.
• The soil should not contaminate by Heavy
metals, pesticidal residues and other
unnatural chemicals
• The use of fertilizers should be minimum.
Irrigation
• Irrigation should be minimized as much as
possible and only applied as per the need of
the plants
• Irrigation water should be free from
contaminants
Crop maintenance
• Tillage should be adapted to enable
good plant growth and must be carried
out whenever required.
• Pesticides and herbicides should be
avoided as far as possible.
Harvesting
• Harvesting should take place when the
plants are of best possible quality,
according to their different utilizations.
Primary Processing: After harvest
includes such processing steps as
washing, freezing, drying etc.
Packaging
• The product should be packed in clean,
dry, bags or cases.
• Label must be clear, permanently fixed
and made from non-toxic material.
Storage and Transport
• Packaged dried materials should be
stored in a dry and well aerated
buildings.
• Fresh product should be stored between
1 to 5ºC
• Frozen products should be stored below
-18ºC or below -20ºC for long term
storage.
Staff Requirements
• The staff who works with the plant
material must have a high degree
of personal hygiene.
• Staff with infectious disease
should not be allowed into the
rooms in which they can come into
contact with the plant.
Documentation
• All the propagation material and
steps in the production process
must be documented.
• All the starting materials,
processing steps including location
of cultivation have to be
documented
Quality
assurance
• Consultation and feedback should
be taken from buyers of medicinal
and aromatic plants regarding the
quality and other properties of
plant material and have an
agreement have to be made.
Pest and Pest
Management
in Medicinal
Plants
Pest is an undesired Animal or Plant
which causes loss of cultivated plants.
Types of Pests
Fungi/Viruses
Insects
Weeds
Non-Insect Pests
Insects
Flies, moth, cutworms,
grasshoppers, spiders, termite etc.
Weeds
A Weed is an undesired plant
They causes depletion and
shortage of nutrients, water,
light, space to the cultivated
plants.
Non insect pests
Vertebrates: Monkeys, rats,
rabbits, squirrels, birds etc.
Invertebrates: Crab's snails,
mites, nematodes etc.
Fungi/Viruses
Ascochyta atropae causes necrosis of
leaf
Cercospora atropae produces leaf spot
disease
METHODS
OF PEST
CONTROL
Mechanical
Method
Agricultural
Method
Biological
Method
Chemical
Method
Biopesticides/Bioinsecticides
for pest Management
These pesticides obtained from natural sources like
microorganisms, plants, animals, insects and certain minerals.
Advantages
They are non-toxic to plants as well as humans
They are biodegradable and do not leave any toxic residues.
They are safe to handle
They are eco-friendly and do not affect soil fertility
They are less expensive
Types of
Biopesticides
Microbial pesticides
Biochemical
pesticides
Plant pesticides
•Thank
You

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Herbs as Raw Materials

  • 1. Herbal Drug Technology Prepared By: Ms. Sweta Kamboj Assistant Professor GGSCOP
  • 2. Herbs As Raw Materials • Introduction: • The interest of people in herbal medicines has increased significantly in both developing and developed countries. • There is a great demand for these herbs, hence there is a need to adopt systematic scientific methods for their selection, cultivation, collection, processing and ensure the quality, purity, safety, potency and develop modern methods for their quality control so that maximum benefit is obtained from these herbal medicines.
  • 3. Herb • It consist of a plant or any part of the plant • Which include entire aerial part leaf, flower, fruit, seed, bark, root, rhizome, tuber or other plant parts. • Herbal Medicine • The definition of herbal medicine is the use of plants to prevent and treat an illness, or to achieve good health as well as the drugs or a plant or plant part or an extract or mixture of these and tinctures that are used.
  • 4. Herbal Medicinal Products • These are the medicinal products which contain exclusive herbal drugs or herbal drug preparations which are made from one or more herbs. • Where the active ingredient consists exclusively of herbal substances or herbal preparations • The term herbal substances denotes whole or parts of plants, algae, fungi. The material is usually dried but sometimes fresh, and is defined by specifying the species full scientific name and the plant part used.
  • 5. Herbal Drug Preparations • Herbal preparations are the basis for finished herbal products and may include comminuted or powdered herbal materials, or extracts, tinctures and fatty oils of herbal materials. • They are produced by extraction with various solvents (polar to non-polar) • Purification • Fractionation • Concentration and other physical and biological process
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  • 13. SOURCES OF HERBS SELECTION, IDENTIfiCATION AND AUTHENTICATION OF HERBAL MATERIALS PROCESSING OF HERBAL RAW MATERIAL
  • 14. Sources of Herbs • Wild source • Cultivated source
  • 15. Wild Source Forests Plains river banks Advantages Obtaining herbs from wild source is easy Economical Less time consuming Low cost of Labour
  • 16. Disadvantages • Unpredictable quality • The plants are not uniform in their growth and yielding characteristics • Modern techniques cannot be applied for increasing the yield Chances of depletion of raw material from the field.
  • 17. Cultivated source • In cultivation we can apply modern techniques such as- • Tissue culture • Genetic engineering • Hybridization • Germ plasm
  • 18. Advantages Quality and purity is ensured Better yield and more profit Ensure regular supply of raw material Application of modern scientific technique is possible
  • 19. Selection of herbal materials Techniques and methods for selecting herbal materials- Randomised approach Ecological approach Chemosystematic approach Ethnoguided approach
  • 20. Identification of herbal materials • Botanical identity • Specimens • Seeds and other propagation materials • Macroscopic characters • Microscopic characters • Chromatographic procedures • Chemical reaction
  • 21. Authentication of herbal materials The steps involved in authentication are: • Taxonomic method • Herbarium coupon sample • Macroscopic method • Microscopic method • Physicochemical method • Spectroscopic method • Chromatographic method • Chemical fingerprinting • Molecular markers
  • 22. Processing of Herbal Raw Material  Primary Processing • Garbling • Washing • Parboiling • Leaching • Drying  Secondary Processing • Cutting • Baking • Boiling • Stir Frying • Fumigation • Extraction
  • 23. Biodynamic Agriculture(Organic Farming Technique) • GAP- Good Agriculture practices in which we increase the productivity of medicinal plants and crop. The main objective of GAP • To improve the quality, safety and effectiveness of final herbal product. • Guide the formation of national monograph for medicinal plant and related standard operating procedure. • Support cultivation and collection of medicinal plant of good quality in order to respect and support the protection of medicinal plant and environment.
  • 24. Guidelines for GAP of Medicinal Plants Seeds and Propagation material • Identified botanically, indicating plant verity, cultivar, chemo type and its origin • Material should be 100% traceable • The parent material of vegetative part used in organic production should be certified and authentically organic Cultivation • Depending upon the method of cultivation • To avoid environmental disturbance care should be taken
  • 25. • Soil and Fertilization • Medicinal and Aromatic plants should not be grown in soils that are contaminated by the sludge. • The soil should not contaminate by Heavy metals, pesticidal residues and other unnatural chemicals • The use of fertilizers should be minimum. Irrigation • Irrigation should be minimized as much as possible and only applied as per the need of the plants • Irrigation water should be free from contaminants
  • 26. Crop maintenance • Tillage should be adapted to enable good plant growth and must be carried out whenever required. • Pesticides and herbicides should be avoided as far as possible. Harvesting • Harvesting should take place when the plants are of best possible quality, according to their different utilizations. Primary Processing: After harvest includes such processing steps as washing, freezing, drying etc.
  • 27. Packaging • The product should be packed in clean, dry, bags or cases. • Label must be clear, permanently fixed and made from non-toxic material. Storage and Transport • Packaged dried materials should be stored in a dry and well aerated buildings. • Fresh product should be stored between 1 to 5ºC • Frozen products should be stored below -18ºC or below -20ºC for long term storage.
  • 28. Staff Requirements • The staff who works with the plant material must have a high degree of personal hygiene. • Staff with infectious disease should not be allowed into the rooms in which they can come into contact with the plant. Documentation • All the propagation material and steps in the production process must be documented. • All the starting materials, processing steps including location of cultivation have to be documented
  • 29. Quality assurance • Consultation and feedback should be taken from buyers of medicinal and aromatic plants regarding the quality and other properties of plant material and have an agreement have to be made.
  • 30. Pest and Pest Management in Medicinal Plants Pest is an undesired Animal or Plant which causes loss of cultivated plants. Types of Pests Fungi/Viruses Insects Weeds Non-Insect Pests
  • 32. Weeds A Weed is an undesired plant They causes depletion and shortage of nutrients, water, light, space to the cultivated plants. Non insect pests Vertebrates: Monkeys, rats, rabbits, squirrels, birds etc. Invertebrates: Crab's snails, mites, nematodes etc.
  • 33. Fungi/Viruses Ascochyta atropae causes necrosis of leaf Cercospora atropae produces leaf spot disease
  • 35. Biopesticides/Bioinsecticides for pest Management These pesticides obtained from natural sources like microorganisms, plants, animals, insects and certain minerals. Advantages They are non-toxic to plants as well as humans They are biodegradable and do not leave any toxic residues. They are safe to handle They are eco-friendly and do not affect soil fertility They are less expensive