1. Phyto-estrogen from natural plant products cures menstrual disorder
Introduction:
Mensuraton is a normal female biological milestone and abnormalities of menstruation are a
major gynecological problem in female. . Menstrual disorders include menstrual irregularity,
menorrhagia, dysmenorrheal, and other related symptoms. Menstrual disorders frequently affect
the quality of life of adolescents and young adult women and can be indicators of serious
underlying problems especially those who suffer dysmenorrheal and heavy menstruation. The
World Health Organization reports that 18 million women aged 30–55 years perceive their
menstrual bleeding to be excessive. Such disorders also have economic consequences in terms of
health care costs due to the consumption of expensive hormonal drugs and laboratory tests. In
addition to health problems other consequences such as limitations on attendance at work and
school which hinder academic achievements and employment prospects.
Menstrual irregularity was reported in 43 to 62% of girls during the first year of menstruation
and in some it persists for 3 to 5 years. 75% of adolescent girls is reported to have menstrual
dysfunction and is known to affect the normal daily chores. Delayed, irregular, painful, and heavy
menstrual bleeding are common occurrence among younger age and are the leading reasons for
physician office visited by adolescents. (Ziv A, Boulet JR, Slap GB. Utilization of physician offices by
adolescents in the United States. Paediatrics.1999;104:35–42. Previous studies have shown a high
prevalence of dysmenorrheal and menstrual irregularity among female students (73% and 65%
respectively) and that these problems affected the women’s social activities and school
attendance. These changes affect their normal functioning and social life. Rigid adherence of traditional
norms and practices, ignorance about menstruation, inadequate health care facilities separately for
unmarried girls etc also restricted their treatment seeking behavior also.
Menopause is a natural event of women’s life’s as they transit from reproductive to non
reproductive stage few years before and after this transition a majority of women encounter
problems like hot flushes, night sweats, palpitations, insomnia, anxiety, irritability, vaginal
dryness, vaginal atrophy, atrophy of cervix and decreases in size of uterus.
Menstruation: Menstruation is the periodic discharge of blood and mucosal tissue from
the inner lining of the uterus through the vagina. It begins with the onset of menarche at or
before sexual maturity and stops at or near menopause.
Menopause: Menopause is defined as the state of an absence of menstrual periods for 12
months. In this state the function of ovary ceases.
Menstrua cycle disorders characterized by Secondary amenorrhoea: (no period during the last 3
months) Oligomenorrhoea (cycle monthly repeated about once every > 32 days), Polymenorrhoea (cycle
repeated about once every ≤ 21 days), Hypomenorrhoea (duration of period < 3 days and slight blood
loss (using < 1 pad), Hypermenorrhoea (duration of period > 7 days and blood loss > 80 mL (using ≥ 5
pads), Dysmenorrhoea (painful menstruation (mild, moderate or severe), PMS (at least 3 of the most
common symptoms occurring 10 days before menstruation and disappearing at the start of
menstruation: painful or tender breasts, bloating or swelling of the abdomen, rapid mood changes,
depressed mood or other (open question).
Man and animals consume plant materials and plant products routinely as part of their
Nutritional requirement. These materials comprise of many known and unknown organic

2. Constituents. The use of naturally occurring substances (natural products) as supplements in the
diet has been under consideration as a possible factor for growth and disease control.
Asparagus (satavari) is a shrub generally used as ayurvedic medicine for giving strength to the
weaker persons/socities, , antioxidant, diuretic, antidepressant, antiepileptic, antitussive, anti-HIV,
immunostimulant, hepato-protective, cardio-protective, antibacterial, anti-ulcerative,
neurodegenerative , person having gastrointenstinal problem, acidity, fever etc. soybean is very
rich in protein, fat, iron etc. adequate amount of soyabean consumption helps in balancing
various hormones.
Objectives:
To regularize the menstrual cycle of young adults.
To increase the iron status in adults.
To overcome the pre-menopausal and post-menopausal symptoms among respective women
Review of literature:
1.According to the author Komal Sharma and Maheep Bhatnagar ,
1
Department of Pharmacology,
B. N. PG College of Pharmacy, Udaipur-313001, Rajasthan, International Journal of
Pharmaceutical & Biological Archives 2011; 2(3):855-863 ,
Asparagus racemosus, traditionally known as shatavari means "who possesses a hundred husbands
or acceptable to many". In Ayurveda it is considered a female tonic. In spite of being a rejuvenating
herb it is beneficial in female infertility, as it increases libido, cures inflammation of sexual organs
and even moistens dry tissues of the sexual organs, enhances folliculogenesis and ovulation, prepares
the womb for conception, prevents miscarriages, acts as post partum tonic by increasing lactation and
normalizing the uterus and the changing hormones. Its use is also advocated in leucorrhoea and
menorrhagia. Shatavari is the main Ayurvedic rejuvenative tonic for the females, as is Withania for
the males.
2. another study has been done by Jhansee Mishra, Alok Kumar Dash,( 1Department of
Pharmacy, Suresh Gyan Vihar University, Jaipur, India. 302025) Suresh Kumar, ,( Department
of Pharmacy, V.B.S.Purvanchal University, Jaunpur,222003), world journal of pharmaceutical
research,. According to the authors Asparagus racemosus is conceivably the best
known as a female rejuvenanitive, used for stimulation of milk production in lactating
women, useful for childlessness, decreased libido, threatened miscarriage, menopause,
leucorrhea and has the capability to balance pH in the cervical area, and as a good remedy for
impotence and general sexual weakness. Asparagus racemosusis mainly known for its
phytoestrogenic properties. With an increasing realization that hormone replacement therapy
with synthetic oestrogens is neither as safe nor as effective as previously envisaged, the interest
in plant-derived oestrogens has increased tremendously making Asparagus racemosus
particularly important.
3.

3. Materials and Methods:
The study will be conducted in Bhubaneswar both in rural and urban area. This will include
female having menstrual problem of age group young adult (18 to 23) and the women of age
(43-53). Total no of 30 subjects will be taken from both the groups. A crossectional survey will
be conducted with a suitable questionnaire. Supplementation will be done to the test group and
the changes will be analyzed stastically to find out the final changes in women subjects.
Criteria for rejection of subjects:
Women having PCOS (Polycystic ovarian syndrome)
Problems at the menarche stage
Bleeding in the clotted forms
Data collection: Data will be collected from the hostel girls regarding various problem like
irregularities of menstruation, cramping, excessive bleeding, duration of cycle, and any other
related health problems.
Expected results: from this study we might get some positive result of curing some of the
symptoms of menstruation disorder by providing supplementation.