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CASE PRESENTATION ON
ACUTE CVA WITH RT FACIO
BRANCHIAL PALSY
PRESENTED BY:
MAHARSHI MALLELA
Y16PHD0815
• Patient’s Name: V
• Sex: MALE
• Age: 66 yrs
• Height: 160cm
• Weight: 54kg
• Physician: DR.C.
• Patient ID: I4000018756
• Date of Admission: XX-XX-XXXX
DEMOGRAPHIC DETAILS
SUBJECTIVE EVIDENCE
• C/O deviation of angle of mouth and tongue to
left side from 3hrs (up to 2hrs)
• C/O slurred speech
• Ex-smoker.
PMx:
• K/C/O Hypertension sine 8yrs
Rx: Tab. Telmisartan 40mg/OD
OBJECTIVE EVIDENCE
VITALS:
• Temp: 98.6F
• RR: 20/min
• PR: 108/min
• BP: 130/80 mm Hg
• P/A: soft
• CVS: S1,S2+
• CNS: Normal
• GCS: E4 V5 M6
ABNORMAL
BIOCHEMICAL TESTS:
1. WBC: 13500* ↑ (4400-
11000)
2. HB: 11.8* ↓ (14-18)
3. PCV: 37* ↓ (42-54)
4. MCHC: 31.8* ↓ (32-37)
5. RDW: 17.2* ↑ (11.6-14)
DIAGNOSTIC PROCEDURES:
 2D-ECHO:
IMP: * LVEF 45%
* CAD
* mild LV dysfunction
*G-I diastolic dysfunction
* 2.9 x 1.6 cm LV apical clot (+)
* Trival MR, TR
 ECG: abnormal
IMP: * SINUS TACHYCARDIA
* ST and T wave abnormality- lateral ischemia
 CAROTID COLOUR DOPPLER STUDY:
IMP: * B/L Intima Media thickening noted (rt- 0.13cm, lt- 0.16cm)
* Focal calcified plaque in lt carotid bulb extending in lt proximal internal
carotid artery. 4x3mm causing 10-20% area stenosis.
 MRI- BRAIN:
IMP: *NO acute infract
? ischemia
ASSESSMENT
CAUSES:
 Age
 Hypertension
 Cigarette smoking
RISK FACTORS:
• Gender, Race, Family history of stroke, Low birth weight
• Atrial fibrillation, Diabetes, Dyslipidemia, Alcohol, Sickle cell
disease, Obesity, Physical inactivity and Diet
COMPLICATIONS:
 Cerebral oedema
 Seizures
 Cardiogenic shock
 Pulmonary embolism, DVT
PLANNING
DRUG CHART:
DRUG NAME DOSE ROA FRQ INDICATION CATEGORY
1. Inj. CLEXANE
(Enoxaparin)
60mg
(6000IU)
S/C BD Prophylactic for
DVT
Anti coagulant-low
molecular weight
heparins
2. Tab. Atorvastatin 40mg P/O OD For lowering lipid
levels (LDL)
HMG CoA reductase
inhibitors or statins
3. Inj. EDASTAR
(Edaravone)
30mg I/V BD For oxidative stress Antioxidants
4. Inj. PANTOCID
(Pantoprazole)
40mg I/V OD Prophylactic use Proton pump
inhibitors (PPIs)
5. Tab. TAZLOC
(Telmisartan)
40mg P/O OD For high blood
pressure
Angiotensin receptor
blockers (ARBs)
6. Tab. RESTYL
(Alprazolam)
0.25mg P/O H/S For anxiety or panic Benzodiazepines
7. Tab. CLOPILET
(Clopidogrel)
75mg P/O BD For stroke Antiplatelets
STANDARD TREATMENT
• Must quickly restore blood flow to the brain
• Emergency treatment:
Tissue plasminogen activator (tPA)- Alteplase
Initial dose: 0.9mg/kg IV bolus over 1hour
Following dose: 0.81mg/kg cont. infusion over 60min
• Antiplate agents and anticoagulants with in 24hrs if alteplase is
not recommended
Aspirin 160-325mg oral with in 48hrs followed by 75-100mg daily
Clopidogrel 75mg oral OD
Combination of aspirin and clopidogrel with in 24hrs upto 21 days
Heparin 70-100units/kg IV bolus
• Medications delivered directly to the brain (catheter)
• Carotid endarterectomy
• Angioplasty and stents
LIFE STYLE MODIFICATIONS
Cerebro-Vascular Accident (CVA)

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Cerebro-Vascular Accident (CVA)

  • 1. CASE PRESENTATION ON ACUTE CVA WITH RT FACIO BRANCHIAL PALSY PRESENTED BY: MAHARSHI MALLELA Y16PHD0815
  • 2. • Patient’s Name: V • Sex: MALE • Age: 66 yrs • Height: 160cm • Weight: 54kg • Physician: DR.C. • Patient ID: I4000018756 • Date of Admission: XX-XX-XXXX DEMOGRAPHIC DETAILS
  • 3. SUBJECTIVE EVIDENCE • C/O deviation of angle of mouth and tongue to left side from 3hrs (up to 2hrs) • C/O slurred speech • Ex-smoker. PMx: • K/C/O Hypertension sine 8yrs Rx: Tab. Telmisartan 40mg/OD
  • 4. OBJECTIVE EVIDENCE VITALS: • Temp: 98.6F • RR: 20/min • PR: 108/min • BP: 130/80 mm Hg • P/A: soft • CVS: S1,S2+ • CNS: Normal • GCS: E4 V5 M6 ABNORMAL BIOCHEMICAL TESTS: 1. WBC: 13500* ↑ (4400- 11000) 2. HB: 11.8* ↓ (14-18) 3. PCV: 37* ↓ (42-54) 4. MCHC: 31.8* ↓ (32-37) 5. RDW: 17.2* ↑ (11.6-14)
  • 5. DIAGNOSTIC PROCEDURES:  2D-ECHO: IMP: * LVEF 45% * CAD * mild LV dysfunction *G-I diastolic dysfunction * 2.9 x 1.6 cm LV apical clot (+) * Trival MR, TR  ECG: abnormal IMP: * SINUS TACHYCARDIA * ST and T wave abnormality- lateral ischemia  CAROTID COLOUR DOPPLER STUDY: IMP: * B/L Intima Media thickening noted (rt- 0.13cm, lt- 0.16cm) * Focal calcified plaque in lt carotid bulb extending in lt proximal internal carotid artery. 4x3mm causing 10-20% area stenosis.  MRI- BRAIN: IMP: *NO acute infract ? ischemia
  • 6. ASSESSMENT CAUSES:  Age  Hypertension  Cigarette smoking RISK FACTORS: • Gender, Race, Family history of stroke, Low birth weight • Atrial fibrillation, Diabetes, Dyslipidemia, Alcohol, Sickle cell disease, Obesity, Physical inactivity and Diet COMPLICATIONS:  Cerebral oedema  Seizures  Cardiogenic shock  Pulmonary embolism, DVT
  • 7. PLANNING DRUG CHART: DRUG NAME DOSE ROA FRQ INDICATION CATEGORY 1. Inj. CLEXANE (Enoxaparin) 60mg (6000IU) S/C BD Prophylactic for DVT Anti coagulant-low molecular weight heparins 2. Tab. Atorvastatin 40mg P/O OD For lowering lipid levels (LDL) HMG CoA reductase inhibitors or statins 3. Inj. EDASTAR (Edaravone) 30mg I/V BD For oxidative stress Antioxidants 4. Inj. PANTOCID (Pantoprazole) 40mg I/V OD Prophylactic use Proton pump inhibitors (PPIs) 5. Tab. TAZLOC (Telmisartan) 40mg P/O OD For high blood pressure Angiotensin receptor blockers (ARBs) 6. Tab. RESTYL (Alprazolam) 0.25mg P/O H/S For anxiety or panic Benzodiazepines 7. Tab. CLOPILET (Clopidogrel) 75mg P/O BD For stroke Antiplatelets
  • 8. STANDARD TREATMENT • Must quickly restore blood flow to the brain • Emergency treatment: Tissue plasminogen activator (tPA)- Alteplase Initial dose: 0.9mg/kg IV bolus over 1hour Following dose: 0.81mg/kg cont. infusion over 60min • Antiplate agents and anticoagulants with in 24hrs if alteplase is not recommended Aspirin 160-325mg oral with in 48hrs followed by 75-100mg daily Clopidogrel 75mg oral OD Combination of aspirin and clopidogrel with in 24hrs upto 21 days Heparin 70-100units/kg IV bolus • Medications delivered directly to the brain (catheter) • Carotid endarterectomy • Angioplasty and stents