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1. Lyme disease vs. Multiple sclerosis
Done By: Dalal F. Alanazi
Medical student at KFU

2. Lyme disease vs. multiple sclerosis
Item Multiple sclerosis Lyme disease
Definition A chronic autoimmune
inflammatory disorder
A bacterial infection
transmitted by a tick.
Cause Multifactorial Borrelia bacteria
Skin - Rash ( early symptom)
Symptoms - Dyarthia, dysphagia,
cognitive impairment.
- Optic neuritis,
nystagmus & diaplopia.
- Spasm & ataxia for
musculoskeletal.
- Headaches, neck stiffness,
malaise, migratory and
intermittent joint pain, and
fatigue.
- Affect the skin, nervous
system, heart.
Systems involved in
symptoms
CNS CNS, PNS (nerves),
Concurrent Versions
System, the liver, the eyes
(causing conjunctivitis) and
joints.

3. Cont..
Item Multiple sclerosis Lyme disease
Signs Upper motor lesions Upper & lower motor
lesions
Investigation - Oligoclonal bands in CSF
the most sensitive
technique.
- Lumbar puncture.
- Enzyme-linked
immunosorbent assay
(ELISA) test.
Detects antibodies to B.
burgdorferi.
Followed by Western blot
test.
- CBC.
Treatment Symptomatic -
“Corticosteroid & Beta
interferons”
Curative - “Doxycycline”