POWER POINT PRESENTATION

1. DNA ReplicationDNA Replication

2. DNA ReplicationDNA Replication
Replication = DNA copies itselfReplication = DNA copies itself exactlyexactly
(Occurs within the nucleus)(Occurs within the nucleus)
 Any mistake in copying =Any mistake in copying = mutationmutation
 DNA mutation = chromosomal mutationDNA mutation = chromosomal mutation

3. A. Basic Facts of DNAA. Basic Facts of DNA
ReplicationReplication
1.1. ComplementaryComplementary
base pairingbase pairing
makesmakes
replication possiblereplication possible
CC -- GG
AA -- TT

4. A. Basic Facts of DNAA. Basic Facts of DNA
ReplicationReplication
2. One side of DNA2. One side of DNA
molecule ismolecule is
aa
templatetemplate
forfor
makingmaking
thethe
other sideother side
(strand)(strand) ?’s 1-3

5. B. Process of DNA ReplicationB. Process of DNA Replication
1.1. Uncoil & unzip DNA moleculeUncoil & unzip DNA molecule
 Enzyme (-ase)Enzyme (-ase) breaksbreaks
weakweak
Hydrogen BondHydrogen Bond
between basesbetween bases

6. B. Process of DNA ReplicationB. Process of DNA Replication
2.2. Enzyme brings in complementary N-basesEnzyme brings in complementary N-bases
DNA Replicase

7. B. Process of DNA ReplicationB. Process of DNA Replication
3.3. Insert N-basesInsert N-bases
DNA Replication TutorialDNA Replication Tutorial
(Go here for on-your-own learning/review)(Go here for on-your-own learning/review)
trc.ucdavis.edu/.../week5/06dnareplication.html

8. Replication MoovieReplication Moovie
CC --
GG
AA -- TT

9. C.C. Semi-conservative replicationSemi-conservative replication
1.1. Each new DNAEach new DNA
moleculemolecule
containscontains
one old strandone old strand
&&
one new strandone new strand
?’s 4-6