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Drug delivery system
1. Drug delivery systems: realistic or optimistic
attitudes
Seyedmohammad Motevalli
Prof. Nie
Spring 2016
2. Drug Delivery System
DDS defined as a formulation
or a device that enables the
introduction of a therapeutic
substance in the body and
improves its efficacy and
safety by controlling the rate,
time and place of release of
drugs in the body.
Jain 2008
6. The primary goals for research of Nano-
biotechnology in drug delivery include:
More specific drug targeting and delivery
Reduction in toxicity while maintaining therapeutic
effects
Greater safety and biocompatibility
Faster development of new safe medicines
23. Late 1970’s Current Era Future
First Nanoscale drug delivery
system was lipid vesicles.
Nowadays, liposomes, cream,
capsule, tablets, gel, aqueous
solution, aerosols/spray are
used as forms of delivery.
Nano enabled technology will
take the maximum share of
the market making up nearly
90% of drug delivery market.
Considered impossible to
administer the
pharmaceuticals suspensions
by intravenous means, due to
obvious risks of embolism.
15% of market uses
nanoparticle for drug delivery
systems.
Safe, Effective and without
side effects. No wastage and
increased bioavailability are
going to be the basis of future
drug delivery.
First paper was published in
1976; it focused on
development of nanoparticle
for vaccine purposes.
More specific for treatment. More-energetic and more-
targeted methods, in which
medications ride passively on
the circulating bloodstream,
where they may or
may not arrive at micro cracks
24. References
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Çağdaş, M., et al. (2014). Liposomes as Potential Drug Carrier Systems for Drug Delivery, INTECH.
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carbon-based drug delivery systems." Science and Technology of Advanced Materials.
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291.
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Chemotherapy of Tumors." Advanced Materials 28(2): 245-253.
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1003.
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therapeutics and diagnostics." Sch. J. App. Med. Sci 2(1C): 328-331.
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References