What is the method of action of aldehydes? They damage proteins They disrupt membranes and DNA They damage nucleic acids They inhibit enzymes. Solution Answer will be 2. Aldehydes disrupts membranes and DNA. Aldehydes like glutaraldehyde and formaldehyde involves a strong association with outer layer of bacterial cells, specifically with unprotonated amines present on the cell surface, representing reactive site. this inhibits transport through the cell leading to inhibition of substrate reaching to rhe enzymes. Action mechanism of aldehydes also include nucleic acid damage by alkylation of amino- , carboxyl- or hydroxyl- group of nucleic acid.