Explain the relationship between three aspects of science: hypothesis, research/experimentation, and theory. Solution The three methods of science hypothesis, research/experimentation, and theory are parts of scientific method. Hypothesis is a rational prediction of causation among various variables. hypothesis is an explanation which is based on limited evidence as a basis of future research. Research is the next step where the hypothesis is tested and studied. It allows to expand the current knowledge with a specific end goal. A refined hypothesis then becomes the theory.