Single Page Apps or SPAs are rich, responsive web applications built with HTML5, CSS, and JavaScript that load all necessary code at once and persist state on the client without full page reloads. Many popular web apps like Gmail and Facebook use SPA architecture. Frameworks like AngularJS, BackboneJS, and KnockoutJS help build SPAs using common patterns like MVC/MVVM and provide templating, data binding, and other functionality. The document provides an example SPA called SPAtube built with KnockoutJS, jQuery, Bootstrap and other libraries that demonstrates a simple SPA for storing YouTube playlists.