Dr. Vladimir Eryomin, Bio-NCP of Russia, email: eryomin@inbi.ras.ru Scientific Officer: Dr. Elisabetta Balzi, email: Elisabetta.Balzi@ec.europa.eu Expected impact: Development of new computational tools for rational enzyme design and improved industrial biocatalysts. Contribution to EU-Russia S&T cooperation.

1. Russian National Contact Point
on «Food, Agriculture, Fisheries & Biotechnology»
(Bio-NCP of Russia on FP6-FP7 Programmes of EC)
Russian Experience in Technology
Platforms Formation (BIO-NCP of Russia)
(BIO-NCP
Vladimir ERYOMIN
Scientific Counsellor of Bio-NCP of Russia
Bach Institute of Biochemistry, RAS
Training Workshop for Russian NCPs
Austrian Research Promotion Agency (FFG)
Vienna, Austria, 1- 5 February 2010 1

2. Presentation outline
Presentation outline
Bio-NCP of Russia
(Basic Information, creation, objectives & tasks, main lines of activities,
etc.)
European and Russian Technology
Platforms on FAFB Priorities
EU-Russia Working Group on Agro-Food-
Biotech Priorities
EU-Russia Co-funded and Coordinated
Calls in FP7 Programme of EC
Russian National Priorities
Prospects for Future EU-Russia RTD Cooperation
2

3. Bio-NCP of Russia
Bio-NCP of Russia
A.N. BACH
A.N. BACH
INSTITUTE OF
INSTITUTE OF
BIOCHEMISTRY
BIOCHEMISTRY
RAS (INBI)
RAS (INBI)
Bio-NCP of Russia (formerly - Food-NCP in FP6) was
established by the Ministry of Science and
Education of the RF on the basis of A.N. Bach
Institute of Biochemistry of Russian Academy of
Sciences in May 2003
The main objective of Bio-NCP of Russia is
promotion of Russian science integration into the
European Research Area («ERA») by participation in
FP6-FP7 Programmes of EC
3

4. Bio-NCP of Russia
Bio-NCP of Russia
Our activity is directed to:
Increasing Russian participation in EC FP7 Programme on
FAFB priorities
Consulting & training organizations and participants,
information assurance and dissemination, accompanying
projects, etc.
Increasing capacity building Russian R&TD community
Consulting and direct contacts with Russian governing bodies
(Government agencies, Ministry of Education &Science of the
RF, stakeholders, multipliers, administration of scientific
Centres and Institutes, SME representatives, etc.) (incl. EU-
Russia Working Group – combining Russian policymakers
and EC Directorate representatives)
Structuring of R&TD community in the Russian Federation
Monitoring and coordination of participation activity in FP7 on
FABF Priorities in the RF
4

5. Bio-NCP of Russia
Bio-NCP of Russia
Main Tasks and Activities
Main Tasks and Activities
Mapping Dissemination All-round help to
Research activities FPs rules, materials EU-Russia Working Group
Revealing and activities and
on Agro-Food-Biotech
Centres of excellence liaison building
(Laboratories, Institutes,
priorities
etc.) , Major R&TD Training & Consulting Communication
infrastructure in Russia Researchers and with EC Directorate
Multipliers and European TP
Revealing Facilitation of
National thematic priorities international contacts, Coordination of R&TD
communications and cooperation
Matching cooperation with other Ministry of Education and
EU and Russian R&TD countries in FPs and Science RF
Priorities Federal Agency for
Structuring Enhancing Science and Innovation
R&TD Community Capacity building NCP,
and acting and potential Participation and holding
Development of bilateral Russian participants of EU-Russia International
collaboration, e.g. with FPs (internal – external) Symposiums, Forums, S&T Events
Germany, … Austria! Co-funded and Coordinated Calls
Involvement and encouragement of acting and potential
Russian participants into FP7 European R&TD Network
5

6. Bio-NCP of Russia
Bio-NCP of Russia
Our activity is directed to:
Studying of European Conception of Technology
Platforms and relevant activity in FAFB Sector of FP7
Revealing Russian National Priorities in FAFB Sector of
FP7
Formation of Russian Technology Platforms in FAFB
Sector of FP7
Coupling of European Conception of Technology
Platforms to development of Technology Platforms in
Russia
Coordination of efforts and activity for Russian participation
in FP7 on FAFB Priorities (EU-Russia Working Group)
Development of joined mechanisms and new ways for RTD
collaboration between EU and Russia (e.g. Co-funded &
co-coordinated Calls, EU-Russia Working Group, and
development of mechanisms for bilateral RTD collaboration) 6

7. European Technology Platforms (TPs)
Technology Platforms (TPs) are the instruments for formation of
priorities for International R&TD co-operation in countries of
the European Union (MS and AC) and other 3-d INCO-
countries co-operating with the EU.
Technology Platforms (TPs) are the practical tools for realization of
FP7 Programme of EC
7

8. Conception of Technology Platforms
Selection of the most strategically important
applied scientific challenges for social and economical
development of EU-countries
Analysis of market needs and available technology
transfers potential for production of consumer’s goods
and service enhancing
Active involvement of all EU-countries and INCO-
countries
Mobilization of public and private financial
resources for FP7 Programme realisation
Mobilization of human resources for implementation
of Projects
8

9. Conception of Technology Platforms
Taking into account all points of view:
(for all interested-in sides)
Government Bodies
Regulatory Bodies
Representatives of Industry
Scientific Communities
SMEs
Multipliers
Consumers and users
The European Conception of
«KNOWLEDGE-BASED BIO-ECONOMY»
9

10. The European Conception of
The European Conception of
«KNOWLEDGE-BASED BIO-ECONOMY»
«KNOWLEDGE-BASED BIO-ECONOMY»
QUALITY ASSURANCE
QUALITY ASSURANCE STABILITY --
STABILITY
STRATEGIES TRACEABILITY,
STRATEGIES TRACEABILITY, SOCIETAL NEEDS
SOCIETAL NEEDS BIODEGRADABILITY
BIODEGRADABILITY
CONSUMER SCIENCE
CONSUMER SCIENCE FUNCTIONALITY
FUNCTIONALITY
Life Sciences &
“Fork to Farm” Biotechnology for
Food, health Sustainable
and well-being non-food products
+ processes
WHITE BIOTECH
ADVANCED FOOD
TECHNOLOGIES, FOOD QUALITY PROCESSING CLEAN BIOPROCESSES
DETERMINANTS, NUTRITION RAW MATERIALS/WASTE
LOW INPUT FARMING -- BIODIVERSITY
LOW INPUT FARMING BIODIVERSITY GREEN/BLUE BIOTECH
GREEN/BLUE BIOTECH
ANIMAL HEALTH -- RURAL DEVT.
ANIMAL HEALTH RURAL DEVT. PRODUCTION OPTIMISED RAW MATERIALS
OPTIMISED RAW MATERIALS
Sustainable production and management of biological resources
from land, forest, and aquatic environments
10
Compiled from Dr. Ch. Patermann presentation

11. European Technology Platforms (TPs)
From: http://cordis.europa.eu/technology-platforms/individual_en.html
11

12. European Technology Platforms (TPs)
TPs of EC are formed on the basis of European
Conception of «Knowledge-Based Bio-Economy»
Food
for Life
Global Animal Bio-Fuels
Health
Knowledge-
Based
Bio-Economy
Forestry Farm Animal
Breeding
Industrial Plants for
Bio-Technology the Future
12

13. Main Activity of Bio-NCP of Russia
in Formation of Russian TPs
Selection of national thematic priorities and national
centres of excellence for formation of Russian TPs
for participation in FP7 Programme of EC
Food Biotechnology
MSU of Applied Biotechnology,
Institute of Nutrition RAMS, etc.
Industrial Biotechnology
Institute Biochemistry RAS, MSU,
Institute of Genetics, etc.
Biotechnology of Plants
Centre of Bio-engineering RAS, etc.
Forestry
MSU of Forest, Centre of Forest
Ecology and Production RAS, etc.
Animal Health
State Institute of Animal Feed, etc. 13

14. Russian TPs on FAFB in FP7
Russian TPs on FAFB in FP7
Russian TPs on FAFB in FP7
Food Quality & Safety
Food Quality & Safety
Industrial Biotechnology
Industrial Biotechnology
Forestry
Forestry
Plants for the Future
Plants for the Future
Animal Health
Animal Health
Fisheries
Fisheries
Bio-fuel
Bio-fuel
14

15. Principles of Russian Technology
Platform Formation
Bio-NCP European
European
Coordinator
Biofuels TP
Biofuels TP
of Russia Centre
Management
Body
Scientific Centre
Scientific Centre Scientific Centre
Scientific Centre Scientific Centre
Scientific Centre Scientific Centre
Scientific Centre
Experts
Experts Experts
Experts Experts
Experts Experts
Experts
Plants for the Future
15

16. Russian Technology Platform
“Food for Life”- STRUCTURE:
Contacts with
BIO-NCP governmental &
of Russia Secretariat legislative
of the Platform bodies
20 members
Research Unions of
Leading food manufacturers Associations
Institutes enterprises in different food of consumers
& Universities industry sectors
Lines of activities:
Food industry Food quality control Healthy nutrition
16

17. Russian Technology Platform
Russian Technology Platform
“Food for Life”- MAIN PARTICIPANTS:
“Food for Life”- MAIN PARTICIPANTS:
MOSCOW STATE
MOSCOW STATE
MOSCOW STATE UNIVERSITY
MOSCOW STATE UNIVERSITY UNIVERSITY
UNIVERSITY
OF APPLIED BIOTECHNOLOGY
OF APPLIED BIOTECHNOLOGY OF FOOD PRODUCTION
OF FOOD PRODUCTION
Institute of MSUFP
Biological Industry
Institute of Fishery Institute of
and Oceanography INSTITUTE OF
INSTITUTE OF A.N. BACH INSTITUTE OF
A.N. BACH INSTITUTE OF Childish Food
NUTRITION
NUTRITION BIOCHEMISTRY RAS
BIOCHEMISTRY RAS
Institute of Institute of Poultry
Processing Industry
Dairy Industry
Institute of Control,
Institute of Standardization, Certifica-
Certifica-
Meat Industry tion of Veterinary
Preparations
17

18. Examples of Russian Consortia
in Technology Platforms
A.N. Bakh Institute Moscow State
GosGNIIgenetika
of Biochemistry, RAS University
Institute
Puschino Research
SME «VOSTOK» of Microbiology
Centre of RAS
of RAS
SME «Rosalko» Institute of Plastics 6 SMEs
Institute of
Centre of Cardiac
Engineering Textile Institute
Surgery RAMS
Ecology
18

19. Structuring of Russian
Biotech Community
19

20. EU-Russia Working Group on
Agro-Food-Biotech Priorities
(Expected or Ideal Structure)
From Russia From EU
Representatives of Ministry Representatives of EC
of Education and Science of Directorate on FAFB priorities
the RF
Representatives of EU
Representatives of Russian
Technology Platforms
Federal Agency for Science
and Innovation
Heads of EU FP6-FP7
Representatives of Bio-NCP Mega-Projects
of Russia
Representatives of European
Representatives of Russian
Bio-NCPs
Technology Platforms
Russian RTD Experts European RTD Experts
(Usually Directors of RTD
Centres)
Secretariat 20

21. EU-Russia Working Group on
Agro-Food-Biotech Priorities
(Scheme of decision making and basic documents)
EU-RF Declaration of Collaboration
RF Topics of Interest EU Topics of Interest
Mutual Topics of Interest
Minutes of WG Meetings
Co-funded and Coordinated Calls
21

22. EC-Russia Coordinated Calls in FP7-TP-FABF
• Date of publication: 30 November 2007 FP7 Call KBBE-2008-2B
• Deadline: 26 February 2008 In Coordination with Russia
• Total budget of call FP7-KBBE-2008-2B: 96.85M€
• Indicative budget dedicated to the coordination activity with Russia: 2+2 M€ (EC+Russia
contribution)
Topic KBBE-2008-3-1-04: Plant-produced vaccines
Topic KBBE-2008-3-2-01: Molecular modelling for rational design of
industrial enzymes
KBBE- Activity 2.3
KBBE-
KBBE- Activity 2.2
KBBE- Biotechnologies 17,56 M €
Food 25,58 M €
KBBE- Activity 2.1
KBBE- KBBE- Activity 2.3
Sustainable Production and Biotechnologies 4 M €
Management of Biological Coordinated & co-funded
Resources 48,21 M €
SCP with Russian
participants
Activity 2.4 - Network of Third
Countries National Information
www.cordis.europa.eu/fp7/kbbe/home_en.htm Points
22
Compiled from Dr. Elisabetta BALZI presentation

23. FABF-TP EC-Russia Coordinated Calls
Date of publication: 30 November 2007
Deadline: 26 February 2008
Indicative budget: 4 M€ (contribution: 2 M€ Russia +2 M€ EC)
Funding Scheme: Small Collaborative Project (SCP)
Topic KBBE-2008-3-1-04:
Plant-Produced Vaccines
(Продуцируемые растениями вакцины)
Topic KBBE-2008-3-2-01:
Molecular Modelling for Rational Design of Industrial
Enzymes (Молекулярное моделирование для рационального дизайна
промышленных ферментов)
All specific arrangements for this particular Call is set out in the relevant Guide
for Applicants
23

24. FABF-TP EC Russia Coordinated Calls
KBBE-2008-3-1-04 : Plant - produced Vaccines
This project will focus on the development of innovative vaccines using plants as
production systems.
Plants offer many advantages over current production platforms by combining the benefits of
traditional fermentor systems (containment, precise growth conditions) with those of plants
(economy, safety, scalability). Specific technologies have been developed recently for the
production of high-value recombinant proteins in plants. Remaining bottlenecks for these
technologies include low yield of recombinant proteins, high production costs and lengthy
development and testing of the plants.
The overall aim of the project will be to identify and establish higher antigen yields
production systems, which are highly controllable and reproducible. This includes the
selection of the most suitable plant species and culture conditions, improved understanding
of antigen presentation and immunity, rapid screening and up-scaling, rapid development of
vaccine variants and novel technologies for improved vaccine production.
Expected impact: High efficiency and low cost production of vaccines. The project is
expected to contribute to the "EU-Russia Common Space for Education and Research" and
to the S&T bilateral agreement between the European Community and the Russian
Federation and to the EU-South Africa dialogue on KBBE on the basis of mutual interest and
shared benefits.
Scientific Officer: Tomasz Calikowski, email: Tomasz.Calikowski@ec.europa.eu 24

25. FABF-TP EC Russia Coordinated Calls
KBBE-2008-3-2-01:
Molecular Modelling for Rational Design of Industrial
Enzymes
Enzymes are increasingly used in the chemical industry. Computational chemistry,
bioinformatics, enzyme structure modelling, molecular docking and dynamics, quantum
chemistry and corresponding hybrid methods have been developed to describe the intimate
details of the bio-catalytic mechanisms.
The objective of the topic is to develop rational enzyme design methods based on molecular
(in-silico) modelling in order to produce a next generation of highly efficient biocatalysts
with an expanded range of substrates, improved enantio-selectivity and enhanced catalytic
activity for industrially important conversions. Optimization of multi-enzyme complexes
should also be considered. Research should address the development of quantitative
parameters which adequately describe the efficiency of the biocatalysts under development.
Improved enzymes are particularly required in certain technological areas, such as fine
organic synthesis, bio-transformations, biomass conversion and the food industry.
Expected impact: Enhance industry's capabilities for rational design of biocatalysts and
their fast quantitative evaluation. The project is expected to contribute to the "EU-Russia
Common Space for Education and Research" and to the bilateral S&T agreement between
the European Community and the Russian Federation, on the basis of mutual interest and 25
shared benefits

26. Indicative Time Table
for EC-Russia Coordinated Calls
EU Russia
Launch of the EC Call 30 November 2007
Launch of the RU Call End of January 2008
Submission deadline EU Call 26 February 2008
Submission Deadline RU Call End of April 2008
Completion of EU evaluation Beginning of April 2008
Completion of RU evaluation Mid of May 2008
End of EU negotiations Mid of July 2008
Signature of EC GA By September 2008
Signature of RU contracts By end of June 2008
Start of projects Starting around the end of 2008
26

27. Call principles
for EC-Russia Coordinated Calls
SMALL COLLABORATIVE PROJECT
Corresponding Joint technical
Russian part in Annex
Integrated
the joint project
Min. 2 RU activities Min. 2-3 MS
participants or AC
participants
Submission
of tender to Submission of
the Russian Joint proposal
< 5% All to FP7 EU-
Call RU of TEC participants
according to participants Russia Call
sign the EU
FASI rules sign a FP7 GA
according to
contract FP7 rules
with FASI
FASI EC
Budget: Budget:
Evaluation EC
Max. 2M€ Max. 2M€
according RU Evaluation
rules EU-RU according
concerted
dialogue
FP7 rules
Compiled from presentation of Gilles Lequeux, European Commission, DG Research
27

28. Overview of the Evaluation Process
EU-RUSSIA Co-ordinated and Co-funded Projects
be ”
ay ote
M m
“re
Individual
Submission Consensus Panel Finalisation
reading
Final
Evaluators Evaluators Evaluators ranking
Full Proposal list
Proposal Rejection list
Criteria Criteria Criteria
forms
Proposals in
Eligibility suggested
priority order
COMMISSION COMMISSION
Role of experts 28

29. FABF-TP EC Russia Coordinated Calls
Minimum Number of Participants:
2 from different EU Member States or FP-Associated
Countries* and
2 from different Federal units (provinces, oblasts,
republics,
territories, districts, Federal cities) from Russia.
* FP-Associated Countries: Croatia, Turkey, Serbia, FYROM, Iceland, Israel, Liechtenstein, Norway,
Switzerland, and as from 01/01/08 Montenegro and Albania
In addition, this research area is particularly well suited for cooperation with other ICPC
countries with bilateral S&T agreements with the European Community** such as South
Africa, and this will be reflected in the evaluation
** ICPC countries with bilateral S&T agreements with the European Community:
Argentina, Brazil, Chile, China, Egypt, India, Mexico, Morocco, Russia, South Africa, Tunisia and Ukraine
29

30. FP7 Funding rules for Collaborative Projects
R&D Activities:
- EU grant up to 50% of the total eligible cost.
- Certain legal entities can receive up to 75% (non-profit
public bodies, Small and Medium Sized Enterprises / SMEs,
higher education establishments).
Demonstration Activities:
- the reimbursement rate may reach 50% of the total eligible cost.
Other activities (consortium management, networking, training,
coordination, dissemination etc. )
- the reimbursement can be up to 100% of the
eligible cost.
30

31. EU‐RUSSIA Symposia
on FP6/7 BIO Priorities
Important instruments to strengthen EU‐
Russian сo‐operation in BIO‐TPs of FP7
‐ I Moscow 2004
‐ II Moscow 2005
‐ III St. Petersburg 2006
‐ IV Suzdal 2007
‐ V Pushchino 2008
‐ German‐Russian Forum in Moscow 2009
31

32. Results of 3 First Calls in FP7 EC
Funded Projects on FAFB Priorities
for 3‐d Countries Participation
11 Projects with Russian Participation
23 Entities from Russia
among them:
2 SICA Calls for Russian Participation
2 EU‐Russia Co‐funded and Coordinated Projects
2007‐2008
32

33. Russian National Priorities
Russian National Priorities in Science, Technology and
Technique Areas:
Biotechnology for life (Industrial Biotechnology for agriculture,
food, forestry, fishery, bio-fuel, etc.)
System Biology (all with –”omics” – genomics, proteomics,
metabolomics, transcritomics, fluxomics, etc.)
Bioengineering technologies
Bio-informatics technologies
Cell technologies including stem cells
Bio-sensing technologies
Biocatalysts and biosynthetic technologies, etc.
Biotechnology for medicine (pharmaceutical, organ therapy, etc.)
Health & Life Sciences (Critical Technologies of the live systems
and in Life Science)
Biomedical technologies for life support and human protection
Genomic and post genomic technologies for drug development
Nanotechnologies and new materials
Information- and telecommunication technologies and electronics
Energy and energy-saving
Advanced and special machinery and equipment development
Environment protection and rational nature management
Security and anti-terrorism activities, etc., etc. 33

34. Prospects for Future EU-Russia Cooperation
Inna Bilenkina, Christian Patermann,
Deputy Head of Russia's Federal Agency for Director of EC Directorate for
Science and Innovation, «Biotechnologies, Agriculture, Fisheries &
CORDIS News interview – «EU and Russia Strengthen Food»
Research Ties» CORDIS Video interview - «Talking about
(http://cordis.europa.eu/fetch?CALLER=KBBENEWS&) FP7» Prospects for Future EU-Russia
Cooperation Initiatives
From 2008, scientific research in Russia will be
Mr. Patermann met his Russian colleagues of
supported from Government by two large scale the EC-Russia Working Group on Agro-Bio-
programmes: Food in Suzdal, Russia and talks about new
First programme is dedicated to the ways in EU-Russia cooperation.
New Materials and Nanotechnologies (~ 40% of Russian funds) (http://cordis.europa.eu/fp7/kbbe/interview_en.
Life Sciences and Biotechnology – (~25%) html)
Energy and Energy Efficiency
Rational Nature Use
Information and Communication Technologies (ICTs).
The second programme is dedicated to the
Industrial Development of Nanotechnologies and New
Materials. 34

35. Russian National Contact Point
on «Food, Agriculture, Fisheries & Biotechnology»
(Bio-NCP of Russia on FP6-FP7 Programmes of EC)
Institute of
Biochemistry
Thank you for your attention
Vladimir ERYOMIN
Scientific Counsellor
(Bio-NCP of Russia)
Institute of Biochemistry, RAS
Leninsky Prospect, 33, 119071 Moscow, RUSSIA
Tel.: +7 (495) 954 44 74
eryomin@inbi.ras.ru
http://www.fp7-bio.ru
35