Ristomed : New E-service for a dietary approach to the elderly

1. NEWSLETTER n°1 Work Package 5 – D 5.1
RISTOMED NEWSLETTER
New e-Services for a Dietary Approach to the Elderly
I NS I DE T H IS I SS U E :
• The Project………………………………………………………………………………………… PAGE 1
• The Secret of an equilibrated Consortium……………………………………….. PAGE 1
• Kick Off Meeting………………………………………………………………………………… PAGE 2
• Dissemination Events………………………………………………………………………… PAGE 3
• RTD Interview : ARNOZAN HOSPITAL (FRA) …………………………………… PAGE 4
The Project
Over the last decade, a real improvement
of ageing conditions has been made
possible by the progresses of medicine and
an increased commitment of public bodies
to this crucial health issue.
As a matter of fact , the fight against
sedentarity and nutritional disorders (such
as obesity or malnutrition) have been
identified as key study factors to prevent
the signs of ageing such as oxidative stress,
inflammation and gut microbiota disorders;
mechanisms that often are at the origin of
serious pathologies for the elderly.
Made to promote the collaboration between
The Secrets of
European countries on key issues and help an Equilibrated
SMEs to access more scientific knowledge
and give substantiality to their products’ Consortium
related claims, the Seventh Framework For the realization of such a project, 8
Programme has enabled the creation of the partners have entered the RISTOMED
RISTOMED Consortium whose partners - Consortium, spread between Research
composed of SMEs and Universitary Centres and Small and Medium Enterprises.
Research Centres (RTDs) - are specialized The goal was gather on one hand, RTDs
in ageing and nutrition related matters. covering all ageing and nutrition related
stakes and, on another hand, SMEs with
Based on a complete study of the European added value nutraceuticals that could, when
eating habits and the known properties of added to a specific diet, produce beneficial
three different nutraceuticals, the project’s effects on the subjects’ health. Four
goal is to develop a e-service/platform to European Hospitals/Research Centres have
enable the elderly people to reach committed themselves in the Project, all
“successful ageing” through an adapted providing specific fields of expertise to
management of their daily diet, taking into enable an advanced research programme
account their health conditions.
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This document, and information as organized herein are developed by the RISTOMED consortium and are its exclusive property:
Vox Net Soc Coop, Rome University La Sapienza, Bologna University ALMA MATER, Medicine University Charité Hospital Berlin, Gerontologie Clinique Centre Henri Choussat Xavier Arnozan
Hospital – Bordeaux, AISA Therapeutics, ACTIAL Farmaceutica, Maison de l’Argan
Copyright (C) 2009 - 2010

2. NEWSLETTER n°1 Work Package 5 – D 5.1
as well as an accurate interpretation of Sciences) , Prof. Patrizia Hrelia (Dept.
potential results. Pharmacology) and Prof. Silvana Hrelia
(Dept. Biochemistry), the University of
Vox Net Società Cooperativa Bologna has gathered the expertise of 4
ROMA – ITALY Departments of one of the most prestigious
European universities for the realization of
Managed by Fabio Buccolini, the Project’s the Project. Their complementary skills in
Coordinator, Vox Net has developed an nutrition and effects on targeted
advanced expertise in developing websites, pathologies and successful ageing
interactive systems and softwares. They promotion, represent a capital stake for the
specific work consist in converting projects project’s results’ interpretation and use.
to advanced e-tools and platforms. Within
the Ristomed Project, Vox Net will put its CHARITE' Hospital Medicine University
“savoir-faire” to convert the project’s datas BERLIN – GERMANY
into a finished E-Service and put the
technology at the service of medicine
progresses. The Ristomed Platform The Charité Universitätsmedizin Berlin is
developed by Vox Net will also stand as a one of the largest and best-established
central communication point for all the university clinics in Europe today. Under
partners. Prof. Lochs responsibility, Charité will bring
to the study its specific expertise in
University of Rome "SAPIENZA" - malnutrition related diseases in people aged
Medical Physiopathology over the 65s and more precisely the
Department - Nutritional evolution of gastrointestinal flora for these
Science ROMA – ITALY patients.
The Food Sciences and Nutrition Institute, HOPITAL XAVIER ARNOZAN
specialized in the nutrients’ study and BORDEAUX – FRANCE
foodstuffs, epidemiological investigation in
the field of nutrition, food education, Represented by Isabelle BOURDEL
nutritional status, food behaviour, elderly MARCHASSON - from the Department of
malnutrition, has fused the knowledge and Clinical Gerontology - and Mrs Christele
research capacities of 2 nutrition BLANC-MISSON – Biology Researcher – the
specialists, Alessandro Pinto ( Graduated in Henry Choussat Xavier Arnozan
Medicine and Surgery, qualified as a Gerontological Centre stands as a reference
Specialist in Food Sciences and Nutrition) in terms of geriatric care and research.
and Lorenzo Donini (graduated in Medicine They have acquired a serious reputation
and Surgery, Specialist in Nutrition over the years thanks to their expertise in
Sciences). Their collaboration on the project optimizing the nutritional habits and
will aim at elaborating the appropriate physical activities of the elderly, the
health promoting diet for the elderly people preservation and improvement of their
involved in the study. living conditions and study of their typical
pathologies and the way to prevent and
ALMA MATER STUDIORUM cure them.
University of Bologna
Interdepartment Centre AISA Therapeutics – PARIS
L.Galvani BOLOGNA – ITALY
Founded by the Prof. Patrizia d’Alessio, an
Composed of Prof. Claudio Franceschi expert in vascular endothelium and anti-
(Dept. Experimental Pathology), Prof. inflammatory strategies, has developed and
Patrizia Brigidi (Dept. Pharmaceutical patented a fruit based molecula with high
2
This document, and information as organized herein are developed by the RISTOMED consortium and are its exclusive property:
Vox Net Soc Coop, Rome University La Sapienza, Bologna University ALMA MATER, Medicine University Charité Hospital Berlin, Gerontologie Clinique Centre Henri Choussat Xavier Arnozan
Hospital – Bordeaux, AISA Therapeutics, ACTIAL Farmaceutica, Maison de l’Argan
Copyright (C) 2009 - 2010

3. NEWSLETTER n°1 Work Package 5 – D 5.1
anti-inflammatory properties. Willing to After this first step everything is started
push further her researches and open new and is accelerating especially regarding the
therapeutics perspectives to her future nutraceutical packaging and randomization
products, Prof. D’Alessio has committed organization and web platform
herself in the project as an SME but also development.
sharing her knowledge as a recognized Only after this first two steps referring to
Hematologist. WP1 and WP3 the recruitment period is
going to start.
ACTIAL Farmaceutica SA
MADEIRA – PORTUGAL The Consortium has agreed that University
of Rome prepare the Clinical Protocol and
Actial Farmaceutica Lda, a company already will represent a central nutritional link
present worldwide and involved in the between all the partners with a crucial work
production of branded formulations, food on the E-tool for all the Research Centres.
supplements, nutraceuticals is involved in
RISTOMED with its VSL#3® food Finally the Official Project Officer Mrs.
supplement. This is a probiotic product Senem Sanal Erginel attended the KOM and
made to balance the intestinal microflora did a nice and fruitful presentation on the
and prevent inflammatory reactions at EU-Commission actions for SMEs especially
gastrointestinal level. regarding CAPACITIES Programme.
LA MAISON DE L’ARGAN
BORDEAUX - FRANCE
Specialized in the production and marketing
of Argan oil both in its cosmetic and
nutritional form, LA MAISON DE L’ARGAN
has teamed with the leading Professor
Zoubida Charrouf from the Morocco Rabat
University to test the effects of Argan oil –
thus enabling to prove new potential effects
and reinforce the existing literature of this
outstanding natural oil.
Kick Off Meeting-KOM
First Year Project
12-14 Nov. 2008
Dissemination Events
During this first official encounter between
the partners, it a real Consortium is born.
2009
The meeting was focused on all the • Biofach Organic Foods Exhibition
necessary administrative and scientific to (www.biofach.de) 19-22 Feb.09
perform the clinical tests have been • Sunday Lecture 15th March CHARITE’
discussed: the redaction of the Clinical • Rome: i-techpartner Healthcare Biotech
Protocol and Ethical Committee approval, Forum 30 & 31 March
the optimization of resources in terms of • Bordeaux Symposium Nutrition et Santé
number of analysis, the development of 2-3 July in collaboration with University
the web platform for the E-Services. of Laval Quebec – CANADA
• PARIS 8 July – IAGG 2009 Symposium
www.gerontologyparis2009.com
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This document, and information as organized herein are developed by the RISTOMED consortium and are its exclusive property:
Vox Net Soc Coop, Rome University La Sapienza, Bologna University ALMA MATER, Medicine University Charité Hospital Berlin, Gerontologie Clinique Centre Henri Choussat Xavier Arnozan
Hospital – Bordeaux, AISA Therapeutics, ACTIAL Farmaceutica, Maison de l’Argan
Copyright (C) 2009 - 2010

4. NEWSLETTER n°1 Work Package 5 – D 5.1
RTD Interview : ARNOZAN HOSPITAL (FRA)
SUCCESSFUL AGEING - THE VISION OF PROFESSOR ISABELLE BOURDEL
MARCHASSON – HENRY CHOUSSAT XAVIER ARNOZAN GERONTOLOGICAL CENTRE
Belonging to the Gerontological pole of HENRY CHOUSSAT XAVIER ARNOZAN HOSPITAL and
gifted with a long experience in managing clinical studies, Pr. Isabelle Bourdel Marchasson
shares her vision of the crucial stakes related to the RISTOMED project.
“We and more particularly the ageing populations all wish to remain healthy and avoid serious
chronicle illnesses such as Alzheimer other kind of dysfunctions. Nowadays, the fight against
sedentarity and nutritional disorders, obesity of malnutrition, is considered as the key success
factor to avoid ageing related troubles. The concept of “eating well” has evolved a lot over the
last decades, from a purely quantitative vision where the patient is evaluated in function of its
corpulence to a qualitative approach where the content of what has been eaten is carefully
studied and analyzed. As a matter of fact, bad nutritional habits lead to oxidative stress and
micro-inflammation but also an increased exposure to cardiovascular, physiological and mental
diseases.
Micro-inflammation, for example, can be provoked by a gut micro biota disequilibrium. There
are numerous way of “eating well” according to the extreme diversity of food habits amongst
European countries and that are also the reflect of their cultures’ richness. To propose a
European Guideline on this specific question we will have to perform a complete study on
European eating habits and try to elaborate a diet able to have an impact on micro-
inflammation, gut microbiota and cardiovascular diseases “………RISTOMED can be considered
as first step along this complex way.
The Gerontological Centre Xavier Arnozan and general and for the RISTOMED Project will bring
its expertise in ageing mechanisms, related pathologies but also in conducting researches with
elderly patients, whether they are healthy or presenting ageing troubles.
Please visit our site www.ristomed.eu for regular updates.
Contact details
Coordinator:
Fabio Buccolini
R&D - RISTOMED Project Manager
Vox Net Società Cooperativa
Via Paisiello,32 – 00198 ROMA ITALY
www.voxnet.eu
email:fabio.buccolini@ristomed.eu
DISCLAIMER: The sole responsibility for the contents
of this newsletter lies with the authors. It does not
represent the opinion of the European Community.
The European Commission is not responsible for any
use that may be made of the information contained
therein.
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This document, and information as organized herein are developed by the RISTOMED consortium and are its exclusive property:
Vox Net Soc Coop, Rome University La Sapienza, Bologna University ALMA MATER, Medicine University Charité Hospital Berlin, Gerontologie Clinique Centre Henri Choussat Xavier Arnozan
Hospital – Bordeaux, AISA Therapeutics, ACTIAL Farmaceutica, Maison de l’Argan
Copyright (C) 2009 - 2010