Vestibular System Anatomy Function - Dr Rohit Bhaskar
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Vestibular system, apparatus of the inner ear involved in balance. The vestibular system consists of two structures of the bony labyrinth of the inner ear, the vestibule and the semicircular canals, and the structures of the membranous labyrinth contained within them. Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education. Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals. We're committed to being your source for expert health guidance. Bhaskar Health and Medical Education. Source : https://www.bhaskarhealth.com Health Shop: https://www.bhaskarhealth.org @drrohitbhaskar @bhaskarhealth #DrRohitBhaskar #BhaskarHealth #Health #Medical #News #Physiotherapy
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Thyroid Disorders - Dr Rohit Bhaskar
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Typhoid Fever - Dr Rohit Bhaskar
Typhoid fever is a bacterial infection that can spread throughout the body, affecting many organs. Without prompt treatment, it can cause serious complications and can be fatal. It's caused by a bacterium called Salmonella typhi, which is related to the bacteria that cause salmonella food poisoning.
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PIVD (Slipped or Herniated Disc): Physiotherapy Treatment
A prolapsed disc is commonly known as ‘slipped disc’, where a disc does not actually slips but the part of the inner softer part of the disc bulges out or herniates through a weakness in the outer part of the disc.
The prolapsed intervertebral disc is also known as herniated disc.
STAGES OF PIVD:
(1) Bulging: At this early stage, the disc is stretched and doesn’t completely return to its normal shape when pressure is relieved. It retains a slight bulge at one side of the disc. Some of the inner disc fibres could be torn and the soft jelly ( nucleus pulposus ) is spiling outwards into the disc fibres but not out of the disc.
(2) Protrusion: At this stage, the bulge is very prominent and the soft jelly centre has spilled out to the inner edge of the outer fibres, barely held in by the remaining disc fibres.
(3) Extrusion: In the case of a herniated spinal disc, the soft jelly has completely spilled out of the disc and now protruding out of the disc fibres.
(4) Sequestration: Here some of the jelly material is breaking off away from the disc into the surrounding area.
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Thyroid Disorders - Dr Rohit Bhaskar
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
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Health Shop: https://www.bhaskarhealth.org
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#Health #Medical #News #Physiotherapy
Typhoid Fever - Dr Rohit Bhaskar
Typhoid fever is a bacterial infection that can spread throughout the body, affecting many organs. Without prompt treatment, it can cause serious complications and can be fatal. It's caused by a bacterium called Salmonella typhi, which is related to the bacteria that cause salmonella food poisoning.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
We're committed to being your source for expert health guidance. Bhaskar Health and Medical Education.
Source : https://www.bhaskarhealth.com
Health Shop: https://www.bhaskarhealth.org
@drrohitbhaskar @bhaskarhealth
#DrRohitBhaskar #BhaskarHealth
#Health #Medical #News #Physiotherapy
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PIVD (Slipped or Herniated Disc): Physiotherapy Treatment
A prolapsed disc is commonly known as ‘slipped disc’, where a disc does not actually slips but the part of the inner softer part of the disc bulges out or herniates through a weakness in the outer part of the disc.
The prolapsed intervertebral disc is also known as herniated disc.
STAGES OF PIVD:
(1) Bulging: At this early stage, the disc is stretched and doesn’t completely return to its normal shape when pressure is relieved. It retains a slight bulge at one side of the disc. Some of the inner disc fibres could be torn and the soft jelly ( nucleus pulposus ) is spiling outwards into the disc fibres but not out of the disc.
(2) Protrusion: At this stage, the bulge is very prominent and the soft jelly centre has spilled out to the inner edge of the outer fibres, barely held in by the remaining disc fibres.
(3) Extrusion: In the case of a herniated spinal disc, the soft jelly has completely spilled out of the disc and now protruding out of the disc fibres.
(4) Sequestration: Here some of the jelly material is breaking off away from the disc into the surrounding area.
Visit: www.bhaskarhealth.com
#BhaskarHealth
#DrRohitBhaskar
#Physiotherapy
Stroke: Physiotherapy Treatment
A stroke, sometimes called a brain attack, occurs when something blocks blood supply to part of the brain or when a blood vessel in the brain bursts. In either case, parts of the brain become damaged or die. A stroke can cause lasting brain damage, long-term disability, or even death.
Website: https://bhaskarhealth.com/
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Polio (Poliomyelitis): Physiotherapy Treatment
Poliomyelitis (polio) is a highly infectious viral disease that largely affects children under 5 years of age. The virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and cause paralysis.
Parkinson Disease: Physiotherapy Treatment
Parkinson’s disease is a brain disorder that causes unintended or uncontrollable movements, such as shaking, stiffness, and difficulty with balance and coordination.
Symptoms usually begin gradually and worsen over time. As the disease progresses, people may have difficulty walking and talking. They may also have mental and behavioral changes, sleep problems, depression, memory difficulties, and fatigue.
Website: https://bhaskarhealth.com/
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Liver and Gall Bladder - Dr Rohit Bhaskar
The liver and gallbladder are the two accessory organs of the gastrointestinal tract, which carry out a multifunctional role that aids digestion and homeostasis. The liver consists of several lobes and receives its blood supply mainly from the hepatic portal vein. This organ also detoxifies the body, so take good care of it because it is your best friend while celebrating after your exams!
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
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Limbic system - Dr Rohit Bhaskar
The limbic system is a set of structures in the brain that deal with emotions and memory. It regulates autonomic or endocrine function in response to emotional stimuli and also is involved in reinforcing behavior .
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Levers in Human Body ( Physiotherapy ) - Dr Rohit Bhaskar
Muscles and bones act together to form levers. A lever is a rigid rod (usually a length of bone) that turns about a pivot (usually a joint). Levers can be used so that a small force can move a much bigger force. This is called mechanical advantage.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
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Immunity ( Medical ) - Dr Rohit Bhaskar
Immunity can be defined as a complex biological system endowed with the capacity to recognize and tolerate whatever belongs to the self, and to recognize and reject what is foreign (non-self).
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
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Principal’s Of Lifting & Moving Patient - Dr Rohit Bhaskar
Casualty lifting is the first step of casualty movement, an early aspect of emergency medical care. It is the procedure used to put the casualty (the patient) on a stretcher.
Developed emergency services use lifting devices, such as scoop stretchers, that allow secured lifting with minimal personnel. Other methods (explained below) can be used when such devices are not available.
Since only stabilised casualties are moved (except in unusual circumstances), the lifting is usually never performed in emergency; emergency movements are sometimes performed to respect the Golden Hour. This depends on the organisation of the medical services and on the specific circumstances.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
We're committed to being your source for expert health guidance. Bhaskar Health and Medical Education.
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Jaundice - Dr Rohit Bhaskar
Jaundice is a condition in which the skin, whites of the eyes and mucous membranes turn yellow because of a high level of bilirubin, a yellow-orange bile pigment. Jaundice has many causes, including hepatitis, gallstones and tumors. In adults, jaundice usually doesn't need to be treated.
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Hydrotherapy - Dr Rohit Bhaskar
Hydrotherapy is the use of water, both internally and externally and at varying temperatures, for health purposes. Also known as water therapy or "water cures," hydrotherapy includes such therapeutic treatments as saunas, steam baths, foot baths, contrast therapy, sitz baths, and colonic cleansing.
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Gait Cycle - Phases & Analysis - Dr Rohit Bhaskar
Human gait depends on a complex interplay of major parts of the nervous, musculoskeletal and cardiorespiratory systems.
The individual gait pattern is influenced by age, personality, mood and sociocultural factors.
The preferred walking speed in older adults is a sensitive marker of general health and survival.
Safe walking requires intact cognition and executive control.
Gait disorders lead to a loss of personal freedom, falls and injuries and result in a marked reduction in the quality of life.
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Spina Bifida - Dr Rohit Bhaskar
Spina bifida is a birth defect in which an area of the spinal column doesn’t form properly, leaving a section of the spinal cord and spinal nerves exposed through an opening in the back.
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BRACHIAL PLEXUS INJURY - Dr Rohit Bhaskar
A brachial plexus injury (BPI), also known as brachial plexus lesion, is an injury to the brachial plexus, the network of nerves that conducts signals from the spinal cord to the shoulder, arm and hand.
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Female Reproductive System - Dr Rohit Bhaskar
The female reproductive system is designed to carry out several functions. It produces the female egg cells necessary for reproduction, called the ova or oocytes. The system is designed to transport the ova to the site of fertilization. Conception, the fertilization of an egg by a sperm, normally occurs in the fallopian tubes. The next step for the fertilized egg is to implant into the walls of the uterus, beginning the initial stages of pregnancy. If fertilization and/or implantation does not take place, the system is designed to menstruate (the monthly shedding of the uterine lining). In addition, the female reproductive system produces female sex hormones that maintain the reproductive cycle.
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Erythropoiesis - Dr Rohit Bhaskar
Erythropoiesis (from Greek 'erythro' meaning "red" and 'poiesis' meaning "to make") is the process which produces red blood cells (erythrocytes), which is the development from erythropoietic stem cell to mature red blood cell.
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Foot Drop: Causes, Symptoms, and Treatment - Dr Rohit Bhaskar
Foot drop, sometimes called drop foot, is a general term for difficulty lifting the front part of the foot. If you have foot drop, the front of your foot might drag on the ground when you walk. Foot drop isn't a disease. Rather, foot drop is a sign of an underlying neurological, muscular or anatomical problem.
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Enzymes - Structure, Classification, and Function - Dr Rohit Bhaskar
Enzymes are proteins that act as biological catalysts (biocatalysts). Catalysts accelerate chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products.
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Cauda Equina Syndrome - Dr Rohit Bhaskar
➤ Cauda equina syndrome (CES) occurs when the nerve roots of the cauda equina are compressed and disrupt motor and sensory function to the lower extremities and bladder.
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Role of Physiotherapy in Hospital - Dr Rohit Bhaskar
Physiotherapy professionally addresses varied population groups of all ages with various health statuses during hospitalization. The services are provided in the various hospitalization frameworks: in acute states in general hospitals, in departments in rehabilitation, geriatric and long-term hospitals (nursing care, complex nursing care, dementia, prolonged and semi-acute ventilation).
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Diabetes Mellitus - Dr Rohit Bhaskar
Diabetes mellitus is a disorder in which the body does not produce enough or respond normally to insulin, causing blood sugar (glucose) levels to be abnormally high. Urination and thirst are increased, and people may lose weight even if they are not trying to.
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Stroke: Physiotherapy Treatment
A stroke, sometimes called a brain attack, occurs when something blocks blood supply to part of the brain or when a blood vessel in the brain bursts. In either case, parts of the brain become damaged or die. A stroke can cause lasting brain damage, long-term disability, or even death.
Website: https://bhaskarhealth.com/
#DrRohitBhaskar
#BhaskarHealth
Polio (Poliomyelitis): Physiotherapy Treatment
Poliomyelitis (polio) is a highly infectious viral disease that largely affects children under 5 years of age. The virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and cause paralysis.
Parkinson Disease: Physiotherapy Treatment
Parkinson’s disease is a brain disorder that causes unintended or uncontrollable movements, such as shaking, stiffness, and difficulty with balance and coordination.
Symptoms usually begin gradually and worsen over time. As the disease progresses, people may have difficulty walking and talking. They may also have mental and behavioral changes, sleep problems, depression, memory difficulties, and fatigue.
Website: https://bhaskarhealth.com/
#DrRohitBhaskar
#BhaskarHealth
Liver and Gall Bladder - Dr Rohit Bhaskar
The liver and gallbladder are the two accessory organs of the gastrointestinal tract, which carry out a multifunctional role that aids digestion and homeostasis. The liver consists of several lobes and receives its blood supply mainly from the hepatic portal vein. This organ also detoxifies the body, so take good care of it because it is your best friend while celebrating after your exams!
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Limbic system - Dr Rohit Bhaskar
The limbic system is a set of structures in the brain that deal with emotions and memory. It regulates autonomic or endocrine function in response to emotional stimuli and also is involved in reinforcing behavior .
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Levers in Human Body ( Physiotherapy ) - Dr Rohit Bhaskar
Muscles and bones act together to form levers. A lever is a rigid rod (usually a length of bone) that turns about a pivot (usually a joint). Levers can be used so that a small force can move a much bigger force. This is called mechanical advantage.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
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Immunity ( Medical ) - Dr Rohit Bhaskar
Immunity can be defined as a complex biological system endowed with the capacity to recognize and tolerate whatever belongs to the self, and to recognize and reject what is foreign (non-self).
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
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Principal’s Of Lifting & Moving Patient - Dr Rohit Bhaskar
Casualty lifting is the first step of casualty movement, an early aspect of emergency medical care. It is the procedure used to put the casualty (the patient) on a stretcher.
Developed emergency services use lifting devices, such as scoop stretchers, that allow secured lifting with minimal personnel. Other methods (explained below) can be used when such devices are not available.
Since only stabilised casualties are moved (except in unusual circumstances), the lifting is usually never performed in emergency; emergency movements are sometimes performed to respect the Golden Hour. This depends on the organisation of the medical services and on the specific circumstances.
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Jaundice - Dr Rohit Bhaskar
Jaundice is a condition in which the skin, whites of the eyes and mucous membranes turn yellow because of a high level of bilirubin, a yellow-orange bile pigment. Jaundice has many causes, including hepatitis, gallstones and tumors. In adults, jaundice usually doesn't need to be treated.
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Hydrotherapy - Dr Rohit Bhaskar
Hydrotherapy is the use of water, both internally and externally and at varying temperatures, for health purposes. Also known as water therapy or "water cures," hydrotherapy includes such therapeutic treatments as saunas, steam baths, foot baths, contrast therapy, sitz baths, and colonic cleansing.
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Gait Cycle - Phases & Analysis - Dr Rohit Bhaskar
Human gait depends on a complex interplay of major parts of the nervous, musculoskeletal and cardiorespiratory systems.
The individual gait pattern is influenced by age, personality, mood and sociocultural factors.
The preferred walking speed in older adults is a sensitive marker of general health and survival.
Safe walking requires intact cognition and executive control.
Gait disorders lead to a loss of personal freedom, falls and injuries and result in a marked reduction in the quality of life.
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Spina Bifida - Dr Rohit Bhaskar
Spina bifida is a birth defect in which an area of the spinal column doesn’t form properly, leaving a section of the spinal cord and spinal nerves exposed through an opening in the back.
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BRACHIAL PLEXUS INJURY - Dr Rohit Bhaskar
A brachial plexus injury (BPI), also known as brachial plexus lesion, is an injury to the brachial plexus, the network of nerves that conducts signals from the spinal cord to the shoulder, arm and hand.
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Female Reproductive System - Dr Rohit Bhaskar
The female reproductive system is designed to carry out several functions. It produces the female egg cells necessary for reproduction, called the ova or oocytes. The system is designed to transport the ova to the site of fertilization. Conception, the fertilization of an egg by a sperm, normally occurs in the fallopian tubes. The next step for the fertilized egg is to implant into the walls of the uterus, beginning the initial stages of pregnancy. If fertilization and/or implantation does not take place, the system is designed to menstruate (the monthly shedding of the uterine lining). In addition, the female reproductive system produces female sex hormones that maintain the reproductive cycle.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
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Erythropoiesis - Dr Rohit Bhaskar
Erythropoiesis (from Greek 'erythro' meaning "red" and 'poiesis' meaning "to make") is the process which produces red blood cells (erythrocytes), which is the development from erythropoietic stem cell to mature red blood cell.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
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Foot Drop: Causes, Symptoms, and Treatment - Dr Rohit Bhaskar
Foot drop, sometimes called drop foot, is a general term for difficulty lifting the front part of the foot. If you have foot drop, the front of your foot might drag on the ground when you walk. Foot drop isn't a disease. Rather, foot drop is a sign of an underlying neurological, muscular or anatomical problem.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
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Enzymes - Structure, Classification, and Function - Dr Rohit Bhaskar
Enzymes are proteins that act as biological catalysts (biocatalysts). Catalysts accelerate chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
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Cauda Equina Syndrome - Dr Rohit Bhaskar
➤ Cauda equina syndrome (CES) occurs when the nerve roots of the cauda equina are compressed and disrupt motor and sensory function to the lower extremities and bladder.
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We're committed to being your source for expert health guidance. Bhaskar Health and Medical Education.
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Role of Physiotherapy in Hospital - Dr Rohit Bhaskar
Physiotherapy professionally addresses varied population groups of all ages with various health statuses during hospitalization. The services are provided in the various hospitalization frameworks: in acute states in general hospitals, in departments in rehabilitation, geriatric and long-term hospitals (nursing care, complex nursing care, dementia, prolonged and semi-acute ventilation).
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
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Diabetes Mellitus - Dr Rohit Bhaskar
Diabetes mellitus is a disorder in which the body does not produce enough or respond normally to insulin, causing blood sugar (glucose) levels to be abnormally high. Urination and thirst are increased, and people may lose weight even if they are not trying to.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
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We're committed to being your source for expert health guidance. Bhaskar Health and Medical Education.
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Foot Drop: Causes, Symptoms, and Treatment - Dr Rohit Bhaskar
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Enzymes - Structure, Classification, and Function - Dr Rohit Bhaskar
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Non-respiratory Functions of the Lungs.pdf
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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BENIGN PROSTATIC HYPERPLASIA.BPH. BPHpdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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The Normal Electrocardiogram - Part I of II
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
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Hemodialysis: Chapter 3, Dialysis Water Unit - Dr.Gawad
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- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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Physiology of Chemical Sensation of smell.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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