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Aqib Umair
l
MID-3
Uterine Fibroids
LEIOMYOMA
Leiomyoma
 Leimyoma are benign tumors that grow
from the muscular wall Myometrium of the
uterus.
 Leiomyoma are composed of Fibrous tissue
and smooth muscels.
 They are the most common uterine tumors.
Etiology
 Unknown
 There may be genetic predisposition
 Leiomyoma contain estrogen receptors in high
concentration than surrounding myometrium.
 They may increase with estrogen therapy and in
pregnency.
Classification
They are classified on the basis of their location in uterus.
o Submucosal leiomyoma
o Pedunculated intracavity
o Intramural
o Subserous
o Pedunculated abdominal
o Parasitic
o Intraligmentary
o Cervical
Submucosl Leiomyoma
present behind mucous layer
Pedunculated intracavity
behind mucous layer and hanging with a stalk
Intramural leiomyoma
located in the center of uterine wall
Subserosal leiomyoma
 Located behind serosal layer
Pedunculated abdominal
It present outside from uterus, in abdomen.
And attached by a stalk
Cervical fibroids
 Present in the neck of cervix
Clinical Findings
PAIN
 vasscular occlusion > infection,necrosis
 Myometrial contraction to expel fibroid
 If goes to pelvic cause nerve compression
and back pain leading to lower extremities
Abnormal uterine bleeding
 Due to distorsion ang congestion of
surrounding vessels
Pressure Effects
 If large may obstruct the nearby organs like
ureters,bladder,rectum.
 Hydronephrosis
 Frequent urination
 May cause bowel obstruction
Infertility
 Infertility occurs mostly by fibroids pedunculted
in the uterine cavity.
Spontaneous Abortions
 Due to pressure of fibroid on fetus to expel
 Mostly due to fibroids pedunculated in cavity
Overview
 Leiomyoma are benign tumors arise from
muscular layer Myometrium of uterus.
 Etiology is unknows but related to estrogen.
Classification
o Submucosal leiomyoma
o Pedunculated intracavity
o Intramural
o Subserous
o Pedunculated abdominal
o Parasitic
o Intraligmentary
o Cervical
Clinical Findings
 Pain
 Uterine Bleeding
 Pressure Effects
 Infertility
 Spontaneous Abortion

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Uterine Fibroids on Ultrasound