The document discusses factors that increase mother-to-child transmission (MTCT) of HIV and strategies to reduce transmission. It states that MTCT can occur during pregnancy, labor and delivery, or postnatally through breastfeeding. Factors that increase risk include high maternal viral load, low CD4 count, advanced HIV disease, STIs, and certain delivery factors. The four key elements for prevention are preventing HIV infection in women, preventing unintended pregnancies in HIV-infected women, preventing transmission from mother to infant, and supporting mothers and families.