This document provides a summary of a presentation on practical MySQL tuning. It discusses measuring critical system resources like CPU, memory, I/O and network usage to identify bottlenecks. It also covers rough tuning of MySQL parameters like the InnoDB buffer pool size, log file size and key buffer size. Further tuning includes application optimizations like query tuning with EXPLAIN, index tuning, and schema design. The presentation also discusses scaling MySQL through approaches like caching, sharding, replication and optimizing architecture and data distribution. Regular performance monitoring is emphasized to simulate increased load and aid capacity planning.