National Institute for Health Research (NIHR)

1. UK-Italy Workshop on Dementia Research
Strategies, Priorities and International Collaboration
January 18 2018
Rome
National Institute for Health
Research (NIHR) Dementia
Research Infrastructure
Martin Rossor
University College London

2. High risk
Pre-
symptomatic
Early
symptomatic
MCI Mild Moderate Severe
IVIIIIII
Basic
Science
CRN
DPUK
Trend to researching earlier populations
Capacity:newtalent,repurposing,incentivisation,citizenscience,datascience Join Dementia
Research
ENRICH
TRC-D
CLAHRCs
DRI
DRI 2020

3. Newcastle Biomedical Research
Centre in Ageing and Long-Term
Conditions
Biomedical
Research Centre
Sheffield
Biomedical Research Centre
Cambridge
Imperial Biomedical Research Centre
Oxford Health Biomedical
Research Centre
Biomedical Research Centre at
South London and Maudsley
NHS Foundation Trust and King’s
College London
University College Hospitals
Biomedical Research Centre
Oxford Biomedical
Research Centre
Dementia Translational Research Collaboration (D-TRC)
The Dementia TRC comprises
eight NIHR Biomedical Research
Centres with dementia-related
research themes.

4. Delivering Clinical Research:
Dementias and Neurodegenerative
Diseases Research Network (DeNDRoN)
• Full national coverage from 15 Local
Clinical Research Networks covering the
whole of England (+ dementia networks
in the devolved nations)
• At both national and local level there are
research delivery divisions, each covering
a set of related specialties
• National co-ordination and leadership

5. Recruitment and number of studies on
the NIHR Portfolio by financial year
0
50
100
150
200
250
300
350
0
5000
10000
15000
20000
25000
30000
35000
40000
2010/11 2011/12 2012/13 2013/14 2014/15 2015/16
DeNDRoN Recruitment Dementia Recruitment DeNDRoN Studies Dementia Studies

6. The ENRICH
toolkit is a
resource to
support
researchers,
care home staff,
residents &
relatives deliver
research in care
homes.
www. enrich.nihr.ac.uk
Enabling Research in Care Homes

7. Early Career Researcher (ECR)
Community Development
• Find a collaborator
• Find funding / job opportunities
• Find supporting tools and
resources
• Peer support
• Share / find sample protocols
• Find events
• Share their work
• Ask an expert
• Find information on
development opportunities
• Network with colleagues
• Journal club
• Access podcasts / webinars
• Get research ideas
• Get support not provided by
smaller institutions

8. Yet still lack of participation
and inequity of access

9. Join Dementia Research
An online and
telephone service that
helps patients and the
public find and take
part in dementia
research studies
Supporting delivery of
Government’s
Challenge on Dementia
2020

10. Multiple registration options

11. Directly connecting volunteers
and researchers

12. Growth since implementation in 2015
31,245
846 183
155 8,12726%

13. Registrants by diagnosis
20%
15%65%
Dementia diagnosis
Memory
problem, no
diagnosis
No memory problem
or diagnosis

14. UK-Italy Workshop on Dementia Research
Strategies, Priorities and International Collaboration
January 18 2018
Rome
National Institute for Health
Research (NIHR) Dementia
Research Infrastructure
Martin Rossor
University College London