Before 3rd monthof IUL: PGC’S undergo mitosis to form
oogonia.
Before7th month of IUL: oogonia multiply mitotically to form
primary oocytes and surrounding by epithelial cells.
7 th month - birth :primary oocytes complete prophase I of
meiotic division and arrested at dictyotene ( diplotene ) stage by
oocyte maturation inhibitor factor till puberty
From birth to puberty follicles are in dormant stage.
6.
After puberty:
● Primaryoocytes undergo maturation and increase in size.
● When the surrounding falt cells converted into cuboid cells it is called
as primary follicle.
● Follicular cells multiply to form multilayered granulosa layer then this
follicle is called secondary follicle.
● When fluid filled cavity ( follicular antrum) appears in the follicular
cells it is called as teritary follicle.
● Tertiary follicle is called matured graffian follicle when it is surrounded
by stromal cells which are condensed to form :
1) Outer fibrous layer-theca externa
2) Inner vascular layer-theca interna
After fertilisation
● Ifovum is fertilized secondary oocyte completes second
meiotic division.
● During second meiosis secondary oocyte pushes second
polar body into perivitalline space.
● If fertilization does not occur secondary oocyte does not
under go meiotic division and under go degeneration in 24
hrs.
● After fertilisation graffian follicle forms into corpus luteum.