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Howard Look
Founder and CEO

howard@tidepool.org
Aaron Neinstein, MD
Director of Clinical Informatics
UCSF Center for Digital Health Innovation
aaron.neinstein@ucsf.edu
0
50
100
150
200
250
300
350
400
450
500
Noon 1pm 2pm 3pm 4pm
Blood Glucose (mg/dL)
Long term complications:
nerve damage, kidney failure,
blindness, amputation
Acute, short term dangers: 

cognitive impairment,
seizure, coma, death
diaTribe.org/42factors
c X
Tools to
Access
Tools to
View
Canon
Olympus
Kodak
Canon
Olympus
Kodak
Our mission:
Make diabetes data more accessible, actionable, and meaningful by
liberating data from diabetes devices, supporting researchers, and
providing great, free software to the diabetes community.
Proudly non-profit.
Freely available.
Simple and secure.
Open Source.
Our Users
People living
with diabetes
Healthcare
Providers
Academic
& Industry
Researchers
Software
Developers
Tidepool

Uploader
tidepool.org/devices
“Would you like to donate your
anonymized diabetes data to support
academic and industry research?”
The Tidepool

Big Data Donation Project
A Diabetes Community Effort
10% of proceeds are shared with our non-profit partners
Industry Partners
• 2,000+ real-world data donors living with diabetes
• 70,000,000+ CGM data points
• 700+ complete, longitudinal datasets with insulin pump & CGM data
• 1,000+ years of patient data
Donor Age Years since Diagnosis Estimated HbA1c
Insights
• Day-to-day insulin use and glycemic variability
• Patient to patient variation from more than 4,000 “N=1” longitudinal datasets
• Aggregate analysis across age groups, years since diagnosis, and more…
Time in Range Hypoglycemia Estimated HbA1c
More insights at tidepool.org/blog
Tidepool Clinical Study Platform
• Vendor neutral - expedites recruiting
• Upload from clinic and home
• Real-time APIs - real-time

protocol compliance monitoring
• Standardized data model for

pumps, CGMs, and BGMs
“It’s OK to get technical with this crowd…”
• Open Source: github.com/tidepool_org
• HIPAA-compliant Hosting: AWS
• Quality System: Google Drive / Google Docs / Trello
• Web Front-end: React, D3, SVG
• Back end: Go, Node, Mongo
• Tidepool Uploader: (old - Chrome App), New - Electron App
• Tidepool Mobile: (old - native), New - React Native
OAuth, JSON and REST APIs
(and why they matter)
OAuth:

Enable access without sharing your password
JSON - A Lightweight Data Interchange Format
{
"_version": 2,
"createdTime": "2015-08-20T00:10:02.342Z",
"deviceId": “DexG5Rec_SM34733123",
"deviceTime": "2015-08-19T17:04:29",
"id": "3bpd8avtbvj6cva2us08b6cl9sm2goi0",
"payload": {
"internalTime": "2015-08-19T15:02:25",
"trend": "Flat"
},
"time": "2015-08-20T00:04:29.000Z",
"timezoneOffset": -420,
"type": "cbg",
"units": "mg/dL",
"value": 117
},
RESTful URL
RESTful API
https://MyMaps.com/location?37.7686,-122.3953
https://tidepool.org/api/user?3b3d7f/cbg/
startDate=2018-01-31T16:45Z&endDate=2018-02-02T07:15Z
“Teens with T1D Study” at Stanford University
is requesting permission to do the following:

Access my basic information
Includes name, email, birthdate.
Access my diabetes device data
Includes blood glucose and insulin delivery data.
Access my activity and fitness data
Includes activity and fitness data.
Tidepool
Logged in as Jill Jellyfish (Not You?)
Ask your developer.
OAuth
JSON
REST APIs
The Power of a Platform:

A Vibrant Ecosystem of Diabetes Applications
Bolus Calculators
Remote Monitoring
Apps for Teens
Clinical Decision
Support
T1D + Fitness Data
Research Apps
and Interfaces
Apps for Pregnant
Moms with T1D
Apps for Kids
Location-aware
Apps
Contextual Meal
Memory
Psycho-social
Research
Artificial PancreasApps for Elderly
Supply

Management
T1D Triathlete

Trainer
T1D

Telemedicine
Single sign-on & SMART-on-FHIR app launch?
Read & import clinical data from EHR?
Write discrete data to EHR?
Import partial note text to EHR?
Import complete summary note to EHR?
Send messages to “InBasket”?
Modify orders or prescriptions in EHR?
What about FHIR? EHR Integration?
Loop
tidepool.org
@Tidepool_org
howard@tidepool.org
aaron.neinstein@ucsf.edu
Clinical Study Platform: research@tidepool.org
Big Data Project: bigdata@tidepool.org

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Tidepool for ONC Innovator Series

  • 1. Howard Look Founder and CEO
 howard@tidepool.org Aaron Neinstein, MD Director of Clinical Informatics UCSF Center for Digital Health Innovation aaron.neinstein@ucsf.edu
  • 2.
  • 3. 0 50 100 150 200 250 300 350 400 450 500 Noon 1pm 2pm 3pm 4pm Blood Glucose (mg/dL) Long term complications: nerve damage, kidney failure, blindness, amputation Acute, short term dangers: 
 cognitive impairment, seizure, coma, death
  • 5. c X
  • 7. Our mission: Make diabetes data more accessible, actionable, and meaningful by liberating data from diabetes devices, supporting researchers, and providing great, free software to the diabetes community. Proudly non-profit. Freely available. Simple and secure. Open Source.
  • 8. Our Users People living with diabetes Healthcare Providers Academic & Industry Researchers Software Developers
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16. “Would you like to donate your anonymized diabetes data to support academic and industry research?” The Tidepool
 Big Data Donation Project
  • 17. A Diabetes Community Effort 10% of proceeds are shared with our non-profit partners Industry Partners
  • 18. • 2,000+ real-world data donors living with diabetes • 70,000,000+ CGM data points • 700+ complete, longitudinal datasets with insulin pump & CGM data • 1,000+ years of patient data Donor Age Years since Diagnosis Estimated HbA1c
  • 19. Insights • Day-to-day insulin use and glycemic variability • Patient to patient variation from more than 4,000 “N=1” longitudinal datasets • Aggregate analysis across age groups, years since diagnosis, and more… Time in Range Hypoglycemia Estimated HbA1c
  • 20. More insights at tidepool.org/blog
  • 21. Tidepool Clinical Study Platform • Vendor neutral - expedites recruiting • Upload from clinic and home • Real-time APIs - real-time
 protocol compliance monitoring • Standardized data model for
 pumps, CGMs, and BGMs
  • 22. “It’s OK to get technical with this crowd…”
  • 23. • Open Source: github.com/tidepool_org • HIPAA-compliant Hosting: AWS • Quality System: Google Drive / Google Docs / Trello • Web Front-end: React, D3, SVG • Back end: Go, Node, Mongo • Tidepool Uploader: (old - Chrome App), New - Electron App • Tidepool Mobile: (old - native), New - React Native
  • 24.
  • 25.
  • 26. OAuth, JSON and REST APIs (and why they matter)
  • 27. OAuth:
 Enable access without sharing your password
  • 28. JSON - A Lightweight Data Interchange Format { "_version": 2, "createdTime": "2015-08-20T00:10:02.342Z", "deviceId": “DexG5Rec_SM34733123", "deviceTime": "2015-08-19T17:04:29", "id": "3bpd8avtbvj6cva2us08b6cl9sm2goi0", "payload": { "internalTime": "2015-08-19T15:02:25", "trend": "Flat" }, "time": "2015-08-20T00:04:29.000Z", "timezoneOffset": -420, "type": "cbg", "units": "mg/dL", "value": 117 },
  • 30. “Teens with T1D Study” at Stanford University is requesting permission to do the following:
 Access my basic information Includes name, email, birthdate. Access my diabetes device data Includes blood glucose and insulin delivery data. Access my activity and fitness data Includes activity and fitness data. Tidepool Logged in as Jill Jellyfish (Not You?)
  • 32. The Power of a Platform:
 A Vibrant Ecosystem of Diabetes Applications Bolus Calculators Remote Monitoring Apps for Teens Clinical Decision Support T1D + Fitness Data Research Apps and Interfaces Apps for Pregnant Moms with T1D Apps for Kids Location-aware Apps Contextual Meal Memory Psycho-social Research Artificial PancreasApps for Elderly Supply
 Management T1D Triathlete
 Trainer T1D
 Telemedicine
  • 33. Single sign-on & SMART-on-FHIR app launch? Read & import clinical data from EHR? Write discrete data to EHR? Import partial note text to EHR? Import complete summary note to EHR? Send messages to “InBasket”? Modify orders or prescriptions in EHR? What about FHIR? EHR Integration?
  • 34. Loop
  • 35. tidepool.org @Tidepool_org howard@tidepool.org aaron.neinstein@ucsf.edu Clinical Study Platform: research@tidepool.org Big Data Project: bigdata@tidepool.org