THROMBOPHYAXIS

1. THROMBOPROPHYLAXIS IN
SURGICAL PATIENTS

2. ● Venous thromboembolism (VTE) - preventable cause of mortality
● Thromboprophylaxis comprise :
1. Mechanical interventions - enhance venous blood flow
2. Anti thrombotic medications - most effective approach

6. THROMBOPROPHYLATIC MEASURES
● Mechanical and pharmacologic
agents
● Mechanical methods serve -
promote venous outflow
● Compression elastic stockings and
intermittent pneumatic compression
are the mechanical methods used for
prophylaxis

7. ● Pharmacological methods
- attenuate coagulation
● Unfractioned heparin (UFH),
low-molecular-weight
heparin (LMWH) and
warfarin, or anti-platelet
agents, particularly Aspirin
(Acetyl salicylic acid), are the
pharmacologic agents

10. ● In neurosurgery, intermittent pneumatic compression or low-dose
LMWH is recommended.
● Acute spinal cord injury patients should receive extended LMWH or
warfarin prophylaxis.
● Trauma patients with major trauma and no contraindications should
receive LMWH thromboprophylaxis.

12. THANK YOU

13. UNIT DECISION
DVT prophylaxis in postoperative patient ;
For all major surgeries
1. Mechanical : DVT stockings/ elastic crepe bandage untill patient is mobilised
2. Pharmacological :
Injection LMWH 0.4ml s/c OD to start 6hrs postoperatively
Continue for 3days minimum / till patient mobilised.
3. No oral anticoagulants required