The Thomas Paul Science Quiz 2015 consists of 20 questions related to physics and chemistry, including topics such as the Bessemer process, the discovery of neutrinos, and significant historical events like the Chernobyl disaster. The quiz rules allow for hints at the quizmaster's discretion and feature star-marked questions for tiebreakers, with the top 6 schools qualifying for the finals. Several scientific discoveries and trivia, including inventions, historical figures, and notable scientific constants, are included in the questions.