A presentation given to human rights and LGBT activists from across Europe in London, September 2010. The conference was organised by the International Lesbian and Gay Association (ILGA)
EEOC and Title VII: Analysis of the EEOC's position on sexual orientation under Title VII, including a discussion of the Supreme Court's same sex marriage ruling in Obergefell v. Hodges and the seemingly competing standards of Title VII.
Recent NLRB Decisions: A discussion of the practical impact of recent NLRB decisions on the day-to-day enforcement of workplace policies, including arbitration agreements, workplace conduct policies, severance agreements and investigation procedures.
Kenya Christian Professionals Forum (KCPF) is an organization founded to support the enhancement of family values in Kenya, with four key pillars namely Life, Family, Religion and Governance. We are an advocacy and networking organization made up of Christian professionals from diverse Christian groups and churches, from diverse professional backgrounds, but all committed to supporting a pro-life, pro-family, pro-religion and good-governance social environment
Rodriguez 1
Diego Rodriguez
Winston Padgett
Government 2305, Sect. 049
Monday, April 14, 2014
Same Sex Marriage: Constitutional and Cultural Considerations Outline
Same sex marriage - is a highly controversial topic in the United States. It impacts our culture and, in many regards to religious beliefs
I. Why and how the U.S. Supreme Court has issued two important rulings that opened up room in constitutional jurisprudence for consideration of gay rights.
A. Yet the vast majority of other states have adopted statutes or constitutional amendments banning same-sex marriage. Do they right to revolt against government tyranny and fight for their rights
B. What states approve of same sex marriage? Which states deny same sex marriage? How has this happen?
II. In this Article, I argue that an individual who marries in her state of domicile and then migrates to a mini-defense of marriage act state has a significant liberty interest under the Fourteenth Amendment's Due Process Clause in the ongoing existence of her marriage.
A. Section 1 ARTICLE IV “Full Faith and Credit shall be given in each State to the public Acts, Records, and judicial Proceedings of every other State. And the Congress may by general Laws prescribe the Manner in which such Acts, Records, and Proceedings shall be proved, and the Effect thereof.”
B. Courts generally agreed right applies to individuals
C. Government permitted to limit some rights of marriage by same sex.
D. Questions today center around: What bans our enforced presently on same sex marriage? Should it be mandatory for gays that want marriage neutral principle grounded in core Due Process Clause values: protection of reasonable expectations and of marital and family privacy, respect for established legal and social practices, and rejection of the idea that a state can sever a legal family relationship merely by operation of law?
III. Court cases outcome for gay marriages
A. The article cites a survey on the constitutional amendment banning gay marriage in the U.S. which found that 50% of the American people are in favor of the amendment banning same-sex marriages while 47% strongly opposed.
B. This survey was conducted by Gallup Poll Ltd. conducted on May 8-11, 2006. Findings also revealed that 66% of the Republicans favor the constitutional amendment defining marriage as a heterosexual institution while 55% of the Democrats opposed the amendment.
C. United States v. Windsor, a narrow majority ruled that Section 3 of the Defense of Marriage Act, which comprehensively defined "marriage" and "spouse" in federal law to exclude same-sex partners, was unconstitutional.
D. In Hollingsworth v. Perry, the Court let stand a trial-court ruling invalidating California's Proposition 8, which outlawed same-sex marriage. Will Fourteenth Amendment still not incorporated to protect gay marriage
IV. There have been and there will continue to be disagreements about the merits of same-sex marriage. But disagree ...
Chapter 2
Contemporary
Ethical Dilemmas
No right is held more sacred, or is more carefully
guarded, by the common law, than the right of
every individual to the possession and control of
his own person, free from all restraint or
interference of others, unless by clear and
unquestioned authority of law.
—Union Pac. Ry. Co. v. Botsford
Learning Objectives (1 of 2)
• Describe various historical events that have had
an impact on the resolution of ethical dilemmas.
• Describe common ethical dilemmas and the
various ethical issues that have in many
instances divided many segments of the
population. Topics include:
– Abortion
– Sterilization
– Artificial insemination
Learning Objectives (2 of 2)
• Topics include:
– Surrogacy
– Organ donations
– Research, experimentation, and clinical
trials
– Human genetics
– Stem cell research
– AIDS
Ethical Dilemmas
• Ethical dilemmas arise in situations where a
choice must be made between unpleasant
alternatives.
• Occur when a choice involves giving up
something good and suffering some bad.
– Should I choose life knowing an unborn child
will be born with severe disabilities?
Noteworthy Historical Events (1 of 11)
58,000–68,000 BC: Neanderthal burial sites
(evidence of belief in an afterlife)
1932–1972: Tuskegee Study of Syphilis
1933–1945: Holocaust
1946: Military Tribunal for War Crimes
1949: International Code of Medical Ethics
1954: Guidelines on Human Experimentation
First kidney transplant
Noteworthy Historical Events (2 of 11)
1960s: Cardiopulmonary resuscitation
1964: WHO guidelines for biomedical research
1968: Harvard Ad Hoc Committee on Brain Death
1970: Patient as a Person
1971: Kennedy Institute of Ethics established
1972: Informed consent (Canterbury v. Spence)
1973: Women’s right to abortion (Roe v. Wade)
Noteworthy Historical Events (4 of 11)
1974: National Research Act
1975: First successful cloning of frogs
1976: Substitute judgment (Karen Ann Quinlan)
First living will legislation enacted
1978: Commission for the Study of Ethical
Problems in Medicine
Noteworthy Historical Events (5 of 11)
1980: Hemlock Society formed to advocate for
physician-assisted dying.
1983: First durable power of attorney legislation
Compassion and Choices
1987: Unethical experiments on children
Noteworthy Historical Events (6 of 11)
1990: Patient Self-Determination Act
Cruzan could have feeding tube removed
Kevorkian assists terminally ill patients in
suicide
Timothy Quill and prescription for death
Derek Humphry’s book Final Exit
Radiation experiments on unknowing
human
subjects
Noteworthy Historical Events (7 of 11)
1993: Patient’s wishes honored
1994: Oregon’s Death with Dignity Act
Michigan makes physician-assisted suicide
illegal
1996: HIPAA
Cloning of Dolly
Fourteenth Amendment and the terminally ill
Noteworthy Historical Events (8 of 11)
1997: Physician-assisted suicide
Kevorki ...
Antimicrobial stewardship to prevent antimicrobial resistanceGovindRankawat1
India is among the nations with the highest burden of bacterial infections.
India is one of the largest consumers of antibiotics worldwide.
India carries one of the largest burdens of drug‑resistant pathogens worldwide.
Highest burden of multidrug‑resistant tuberculosis,
Alarmingly high resistance among Gram‑negative and Gram‑positive bacteria even to newer antimicrobials such as carbapenems.
NDM‑1 ( New Delhi Metallo Beta lactamase 1, an enzyme which inactivates majority of Beta lactam antibiotics including carbapenems) was reported in 2008
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
More Related Content
Similar to The use of litigation to advance trans rights
EEOC and Title VII: Analysis of the EEOC's position on sexual orientation under Title VII, including a discussion of the Supreme Court's same sex marriage ruling in Obergefell v. Hodges and the seemingly competing standards of Title VII.
Recent NLRB Decisions: A discussion of the practical impact of recent NLRB decisions on the day-to-day enforcement of workplace policies, including arbitration agreements, workplace conduct policies, severance agreements and investigation procedures.
Kenya Christian Professionals Forum (KCPF) is an organization founded to support the enhancement of family values in Kenya, with four key pillars namely Life, Family, Religion and Governance. We are an advocacy and networking organization made up of Christian professionals from diverse Christian groups and churches, from diverse professional backgrounds, but all committed to supporting a pro-life, pro-family, pro-religion and good-governance social environment
Rodriguez 1
Diego Rodriguez
Winston Padgett
Government 2305, Sect. 049
Monday, April 14, 2014
Same Sex Marriage: Constitutional and Cultural Considerations Outline
Same sex marriage - is a highly controversial topic in the United States. It impacts our culture and, in many regards to religious beliefs
I. Why and how the U.S. Supreme Court has issued two important rulings that opened up room in constitutional jurisprudence for consideration of gay rights.
A. Yet the vast majority of other states have adopted statutes or constitutional amendments banning same-sex marriage. Do they right to revolt against government tyranny and fight for their rights
B. What states approve of same sex marriage? Which states deny same sex marriage? How has this happen?
II. In this Article, I argue that an individual who marries in her state of domicile and then migrates to a mini-defense of marriage act state has a significant liberty interest under the Fourteenth Amendment's Due Process Clause in the ongoing existence of her marriage.
A. Section 1 ARTICLE IV “Full Faith and Credit shall be given in each State to the public Acts, Records, and judicial Proceedings of every other State. And the Congress may by general Laws prescribe the Manner in which such Acts, Records, and Proceedings shall be proved, and the Effect thereof.”
B. Courts generally agreed right applies to individuals
C. Government permitted to limit some rights of marriage by same sex.
D. Questions today center around: What bans our enforced presently on same sex marriage? Should it be mandatory for gays that want marriage neutral principle grounded in core Due Process Clause values: protection of reasonable expectations and of marital and family privacy, respect for established legal and social practices, and rejection of the idea that a state can sever a legal family relationship merely by operation of law?
III. Court cases outcome for gay marriages
A. The article cites a survey on the constitutional amendment banning gay marriage in the U.S. which found that 50% of the American people are in favor of the amendment banning same-sex marriages while 47% strongly opposed.
B. This survey was conducted by Gallup Poll Ltd. conducted on May 8-11, 2006. Findings also revealed that 66% of the Republicans favor the constitutional amendment defining marriage as a heterosexual institution while 55% of the Democrats opposed the amendment.
C. United States v. Windsor, a narrow majority ruled that Section 3 of the Defense of Marriage Act, which comprehensively defined "marriage" and "spouse" in federal law to exclude same-sex partners, was unconstitutional.
D. In Hollingsworth v. Perry, the Court let stand a trial-court ruling invalidating California's Proposition 8, which outlawed same-sex marriage. Will Fourteenth Amendment still not incorporated to protect gay marriage
IV. There have been and there will continue to be disagreements about the merits of same-sex marriage. But disagree ...
Chapter 2
Contemporary
Ethical Dilemmas
No right is held more sacred, or is more carefully
guarded, by the common law, than the right of
every individual to the possession and control of
his own person, free from all restraint or
interference of others, unless by clear and
unquestioned authority of law.
—Union Pac. Ry. Co. v. Botsford
Learning Objectives (1 of 2)
• Describe various historical events that have had
an impact on the resolution of ethical dilemmas.
• Describe common ethical dilemmas and the
various ethical issues that have in many
instances divided many segments of the
population. Topics include:
– Abortion
– Sterilization
– Artificial insemination
Learning Objectives (2 of 2)
• Topics include:
– Surrogacy
– Organ donations
– Research, experimentation, and clinical
trials
– Human genetics
– Stem cell research
– AIDS
Ethical Dilemmas
• Ethical dilemmas arise in situations where a
choice must be made between unpleasant
alternatives.
• Occur when a choice involves giving up
something good and suffering some bad.
– Should I choose life knowing an unborn child
will be born with severe disabilities?
Noteworthy Historical Events (1 of 11)
58,000–68,000 BC: Neanderthal burial sites
(evidence of belief in an afterlife)
1932–1972: Tuskegee Study of Syphilis
1933–1945: Holocaust
1946: Military Tribunal for War Crimes
1949: International Code of Medical Ethics
1954: Guidelines on Human Experimentation
First kidney transplant
Noteworthy Historical Events (2 of 11)
1960s: Cardiopulmonary resuscitation
1964: WHO guidelines for biomedical research
1968: Harvard Ad Hoc Committee on Brain Death
1970: Patient as a Person
1971: Kennedy Institute of Ethics established
1972: Informed consent (Canterbury v. Spence)
1973: Women’s right to abortion (Roe v. Wade)
Noteworthy Historical Events (4 of 11)
1974: National Research Act
1975: First successful cloning of frogs
1976: Substitute judgment (Karen Ann Quinlan)
First living will legislation enacted
1978: Commission for the Study of Ethical
Problems in Medicine
Noteworthy Historical Events (5 of 11)
1980: Hemlock Society formed to advocate for
physician-assisted dying.
1983: First durable power of attorney legislation
Compassion and Choices
1987: Unethical experiments on children
Noteworthy Historical Events (6 of 11)
1990: Patient Self-Determination Act
Cruzan could have feeding tube removed
Kevorkian assists terminally ill patients in
suicide
Timothy Quill and prescription for death
Derek Humphry’s book Final Exit
Radiation experiments on unknowing
human
subjects
Noteworthy Historical Events (7 of 11)
1993: Patient’s wishes honored
1994: Oregon’s Death with Dignity Act
Michigan makes physician-assisted suicide
illegal
1996: HIPAA
Cloning of Dolly
Fourteenth Amendment and the terminally ill
Noteworthy Historical Events (8 of 11)
1997: Physician-assisted suicide
Kevorki ...
Antimicrobial stewardship to prevent antimicrobial resistanceGovindRankawat1
India is among the nations with the highest burden of bacterial infections.
India is one of the largest consumers of antibiotics worldwide.
India carries one of the largest burdens of drug‑resistant pathogens worldwide.
Highest burden of multidrug‑resistant tuberculosis,
Alarmingly high resistance among Gram‑negative and Gram‑positive bacteria even to newer antimicrobials such as carbapenems.
NDM‑1 ( New Delhi Metallo Beta lactamase 1, an enzyme which inactivates majority of Beta lactam antibiotics including carbapenems) was reported in 2008
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERY
The use of litigation to advance trans rights
1. Use of Litigation in the UK
to advance trans rights
Christine Burns MBE
Friday 24th September 2010
2. About Press for Change
• Formed in 1992
• “To campaign to achieve equality and
human rights for all trans people in the
UK through legislation and social change
• 7 Vice Presidents
• Non-hierarchic, facilitative, approach
• No office, no secretariat. A bedroom-
based campaign
3. Trans rights in the UK in
the early 1990’s
• Unchanged since 1970
• Defined by outcome of Corbett v
Corbett case (April Ashley) in 1970
and R v Tan 1974
• Not affected by Sex Discrimination
Act (1975)
http://www.pfc.org.uk/node/319
4. Trans Rights in 1992
• Change name YES
• Change documents YES
• Change birth certificate NO
• Marry in assigned gender NO
• Employment protection NO
• Goods, services, housing NO
• Rape / sexual offences NO
5. Case 1 – P vs S and
Cornwall County Council
• Unfair dismissal on notification of
intended transition
• Employer believed standard
comparator (man vs woman) meant
there was no sex discrimination
• Employment tribunal sought ECJ
ruling on application of Equal
Treatment Directive
6. Case 1 – Key Points
• Plaintiff anonymity / reporting
restrictions
• Novel comparator
• Advocate Tesauro’s recommendation
(Changing sex is an ‘aspect’ of sex)
See also Diane Schroer v Library of Congress for
very similar circumstances and outcome
7. … to maintain that the unfavourable
treatment suffered by P. was not on grounds
of sex because it was due to her change of
sex or else because in such a case it is not
possible to speak of discrimination between
the two sexes would be a quibbling
formalistic interpretation and a betrayal of
the true essence of that fundamental and
inalienable value which is equality.
from Advocate General Tesauro’s opinion
8. Case 1 – Outcome
• Immediate EC-wide effect
• UK Government amended SDA in 1999
(but note special exceptions)
• Forced employers to address
transition rather than getting rid of
the ‘problem’
• 11 years later, still no evidence of
detriment to society
• Hasn’t eliminated discrimination
9. Case 2 – X, Y & Z vs UK
• Legal parenthood
• Pursuing the right accorded to non-
married cis-gender male partners to
place their name on birth certificate
of female partner’s children
• Case framed around the child’s rights
10. Case 2 – Outcome
• Lost, but… ECHR recognised the
existence of ‘family life’
X, Y & Z v UK held that in determining whether a
relationship can amount to “family life” numerous
factors may be relevant; “including whether a couple
live together, the length of their relationship and
whether they have demonstrated commitment to each
other by having children or by any other means.”
In this case a transsexual man, his female partner
and child constituted “family life” under
Article 8 (1997) 24 EHRR 143.
11. Case 3 – Goodwin & I vs UK
• Article 8 and 12 rights (+14)
• Two cases heard together
• Preceeded by
• Rees vs UK (1985)
• Cossey vs UK (1990)
• Sheffield & Horsham vs UK (1998)
12. Case 3 – Outcome
• Won, unanimously
• Court accepted substantial evidence
of discrimination resulting from
inability to alter birth certificate
and be certain of legal status
• Decision referred to proportionality
• Led to Gender Recognition Act 2004
• Not dependent on specific surgeries
13. Para 83. The Court is not persuaded therefore that the state of
medical science or scientific knowledge provides any determining
argument as regards the legal recognition of transsexuals.
Para 90. In the twenty first century the right of transsexuals to
personal development and to physical and moral security in the full
sense enjoyed by others in society cannot be regarded as a matter
of controversy requiring the lapse of time to cast clearer light on
the issues involved. In short, the unsatisfactory situation in which
post-operative transsexuals live in an intermediate zone as not
quite one gender or the other is no longer sustainable
Para 93. …the Court finds that the respondent Government can no
longer claim that the matter falls within their margin of appreciation,
save as regards the appropriate means of achieving recognition of the
right protected under the Convention. Since there are no significant
factors of public interest to weigh against the interest of this
individual applicant in obtaining legal recognition of her gender re-
assignment, it reaches the conclusion that the fair balance that is
inherent in the Convention now tilts decisively in favour of the
applicant. There has, accordingly, been a failure to respect her right
to private life in breach of Article 8 of the Convention.
14. Domestic Cases
• A vs West Yorkshire Police
• A, D & G vs NW Lancs Health
Authority
• Bellinger v Bellinger
For a full list and judgements see:
http://www.pfc.org.uk/legal
15. Trans Rights in 2010
• Change name YES
• Change documents YES
• Change birth certificate YES
• Marry in assigned gender YES
• Employment protection YES
• Goods, services, housing YES
• Rape / sexual offences YES
16. But remember…
Changing the law by judicial or legislative
means doesn’t prevent discrimination. The
most the law can do is to provide a remedy
after discrimination has taken place, or to
encourage change. REAL CHANGE requires
social campaigning (and time)