The document discusses the Royal Society of Chemistry's (RSC) efforts to reflect changes in the digital world through its e-Science initiatives and global chemistry network. It summarizes RSC's work on knowledgebases like ChemSpider, which contains over 29 million chemicals and reactions. It also discusses challenges of big data, text mining, crowdsourcing data quality, and developing new interfaces to improve access and navigation of chemical information online. The goal is to build a global network to share standardized chemistry data and tools to advance science.